小脑性共济失调疾病与其眼神经病表现

神经眼科是一门交叉学科,横跨了眼科、神经内科和神经外科。很多神经系统疾病都会有其相对应的眼神经病表现。神经内科和神经外科临床医生对这些眼神经病表现进行学习,有助于解决因缺乏神经眼科知识而延误与神经疾病相关眼神经病的诊断及治疗困难的难题。文中主要介绍了5种小脑性共济失调疾病与其眼神经病表现。

糖尿病的眼部神经病变

糖尿病的眼部神经病变是糖尿病最常见的并发症之一，临床上时有所见。现将我院1987～1997年遇到的病例报告如下。

中西医结合治疗糖尿病眼部神经病变16例临床体会

目的应用美国礼来公司生产的优沁林30R与自拟中药益气活血通络汤治疗糖尿病眼部神经病变。方法 16例糖尿病眼部神经病变患者均采用美国产优泌林30R控制血糖,每天2次于早、晚餐前皮下注射,同时采用自拟中药益气活血通络汤治疗眼部神经病变。结果症状全部消失,患眼完全恢复正常14例,占87%,好转,患眼上、下视运动障碍有所减轻2例,占12.5%。结论在治疗方面我们采用了中西医结合的方法取得了满意的疗效。

Peripheral Nerve and Transgene Cells Transplantation in the Treatment of Experimental Neuropathy of SD Rats

Purpose: To observe whether optic nerve can regenerate by peripheral nerve transplantation and GDNF gene transfer.Methods: Optic nerve was transected about 2 mm posterior to the eye to establish experimental models of optic neuropathy. Sciatic nerve was sutured to the sheath of injury optic nerve by a 10 - 0 nylon, pcDNA3-GDNF was smeared to the joint and injected to the vitreous cavity. The regenerated retinal ganglion cells axons were observed by HRP. The retina and optic nerve were observed by pathohistological methods.Results: Some retinal ganglion cells with regenerated axons could be seen a week after transplantation with large cell bodies. The cells could be identified by HRP. The regenerated nerve fibers grew to the transplanted sciatic nerve. Then the number of retinal ganglion cells with regenerated axons increased with time going. Only a few regenerated retinal ganglion cells could be seen two months after transplantation. The large retinal ganglion cells were seen to have plenty of

Optic neuropathy and increased retinal glial fibrillary acidic protein due to microbead-induced ocular hypertension in the rabbit

AIMTo 描绘有 intraocular 压力( IOP )的长期的举起的一个绿内障模型是否能被 microbeads 的前面的房间注射在 rabbits.METHODSIn 顺序劝诱屏蔽 microbead 的最佳的剂量注射， IOP 被测量为用在 10 的单个 intracameral 注射以后的手持 applanation 音调测定器的 4wk 的每 3d 吗？