Purpose: To report periocular linear basal cell carcinoma (BCC) as a distinct clinical entity,and to highlight its existence in the ophthalmic literature. Design: Retrospective,noncomparative,multicenter,interventiona...Purpose: To report periocular linear basal cell carcinoma (BCC) as a distinct clinical entity,and to highlight its existence in the ophthalmic literature. Design: Retrospective,noncomparative,multicenter,interventional small case series. Participants: Four patients with linear BCC in the periocular region. Intervention: All patients underwent margin-controlled excision,3 utilizing Mohs’ micrographic surgery and 1 using frozen section. Main Outcome Measures: Age,gender,location,preoperative tumor size,histological growth pattern,presence of perineural invasion,number of Mohs’ levels used to obtain histologic clearance,postoperative defect size,and recurrence. Results: In all 4 cases,the site of occurrence was in the lower eyelid and cheek. Histology revealed pigmented nodular BCC with an infiltrative component in 2 cases and nodular BCC in the remaining 2 cases. No perineural invasion was noted in any of the cases. Two Mohs’ levels were required for complete excision in 3 patients. Conclusions: Linear BCC is a distinct clinical entity. Presence of the tumor along relaxing skin tension lines,increase in subclinical extension,and aggressive tumor behavior are reported observations. Because of these observations,it is suggested that margin-controlled excision should be considered for linear BCC.展开更多
文摘Purpose: To report periocular linear basal cell carcinoma (BCC) as a distinct clinical entity,and to highlight its existence in the ophthalmic literature. Design: Retrospective,noncomparative,multicenter,interventional small case series. Participants: Four patients with linear BCC in the periocular region. Intervention: All patients underwent margin-controlled excision,3 utilizing Mohs’ micrographic surgery and 1 using frozen section. Main Outcome Measures: Age,gender,location,preoperative tumor size,histological growth pattern,presence of perineural invasion,number of Mohs’ levels used to obtain histologic clearance,postoperative defect size,and recurrence. Results: In all 4 cases,the site of occurrence was in the lower eyelid and cheek. Histology revealed pigmented nodular BCC with an infiltrative component in 2 cases and nodular BCC in the remaining 2 cases. No perineural invasion was noted in any of the cases. Two Mohs’ levels were required for complete excision in 3 patients. Conclusions: Linear BCC is a distinct clinical entity. Presence of the tumor along relaxing skin tension lines,increase in subclinical extension,and aggressive tumor behavior are reported observations. Because of these observations,it is suggested that margin-controlled excision should be considered for linear BCC.