9918748 眼附件的淋巴增殖性病损:112例分析/Coupland S E∥J Am Acad Ophthalmol.-1998,105(8).-1430～1441 北医图 9918749 Sjogren综合征患者睑板腺功能不全/Shimazaki J∥J Am Acad Ophthalmol.-1998,105(8).-1485～1488
Background: The concomitant occurrence of both intraocular and periocular lymp homas is extremely rare. Periocular involvement by lymphoproliferative disease r anges from benign lymphoid hyperplasia to malignant lymph...Background: The concomitant occurrence of both intraocular and periocular lymp homas is extremely rare. Periocular involvement by lymphoproliferative disease r anges from benign lymphoid hyperplasia to malignant lymphoma. Intraocular lympho mas usually appear in conjunction with primary central nervous system lymphoma. Case Reports: We describe clinical characteristics, standardized A-and B-scan ultrasonography, colour Doppler, computerized tomographic and magnetic resonance imaging, and immunohistological findings in three cases of concurrent choroidal and periocular involvement of lymphoma. Discussion: The clinical presentation o f diffuse choroidal tumours may be variable, making diagnosis of intraocular lym phoma troublesome on clinical grounds alone. The high accuracy of colour Doppler imaging is known to be effective in differentiating the benign from the maligna nt and adds valuable information in the differential diagnosis of a low reflecti ve lesion. We suggest the use of auxiliary examinations such as ultrasonography and colour Doppler imaging to help in the differential diagnosis of choroidal an d orbital tumours.展开更多
Purpose: To investigate whether activated B lymphocytes ( CD23 ) , activated T lymphocytes (CD25) ,macrophages(CD68) and human leucocyte antigen class II antigen (HLA- DR) were existed in epiretinal membranes (ERMs) a...Purpose: To investigate whether activated B lymphocytes ( CD23 ) , activated T lymphocytes (CD25) ,macrophages(CD68) and human leucocyte antigen class II antigen (HLA- DR) were existed in epiretinal membranes (ERMs) and subretinal membranes (SRMs) of prolif-erative intraocular disorders (PID).Methods : Twenty specimens of ERMs from rhegmatogenous retinal detachment with prolifera-tive vitreoretinopathy( PVR), traumatic PVR and secondary traction retinal detachment, and two specimens of SRMs from rhegmatogenous retinal detachment with PVR and traumatic PRV were studied using immunohistochemical staining.Results: CD68 and HLA - DR were found in all specimens, CD23 and CD25 in 4 cases of ERMs and in 1 case of SRMs, respectively.Conclusions : 1. The ERMs and SRMs of different etiology shared a common basis of inflammation and immunopathology. 2. There would be secondary cellular and humoral immunity in the ERMs and the SRMs of PID. Eye Science 1998; 14:35 - 40.展开更多
文摘9918748 眼附件的淋巴增殖性病损:112例分析/Coupland S E∥J Am Acad Ophthalmol.-1998,105(8).-1430～1441 北医图 9918749 Sjogren综合征患者睑板腺功能不全/Shimazaki J∥J Am Acad Ophthalmol.-1998,105(8).-1485～1488
文摘Background: The concomitant occurrence of both intraocular and periocular lymp homas is extremely rare. Periocular involvement by lymphoproliferative disease r anges from benign lymphoid hyperplasia to malignant lymphoma. Intraocular lympho mas usually appear in conjunction with primary central nervous system lymphoma. Case Reports: We describe clinical characteristics, standardized A-and B-scan ultrasonography, colour Doppler, computerized tomographic and magnetic resonance imaging, and immunohistological findings in three cases of concurrent choroidal and periocular involvement of lymphoma. Discussion: The clinical presentation o f diffuse choroidal tumours may be variable, making diagnosis of intraocular lym phoma troublesome on clinical grounds alone. The high accuracy of colour Doppler imaging is known to be effective in differentiating the benign from the maligna nt and adds valuable information in the differential diagnosis of a low reflecti ve lesion. We suggest the use of auxiliary examinations such as ultrasonography and colour Doppler imaging to help in the differential diagnosis of choroidal an d orbital tumours.
文摘Purpose: To investigate whether activated B lymphocytes ( CD23 ) , activated T lymphocytes (CD25) ,macrophages(CD68) and human leucocyte antigen class II antigen (HLA- DR) were existed in epiretinal membranes (ERMs) and subretinal membranes (SRMs) of prolif-erative intraocular disorders (PID).Methods : Twenty specimens of ERMs from rhegmatogenous retinal detachment with prolifera-tive vitreoretinopathy( PVR), traumatic PVR and secondary traction retinal detachment, and two specimens of SRMs from rhegmatogenous retinal detachment with PVR and traumatic PRV were studied using immunohistochemical staining.Results: CD68 and HLA - DR were found in all specimens, CD23 and CD25 in 4 cases of ERMs and in 1 case of SRMs, respectively.Conclusions : 1. The ERMs and SRMs of different etiology shared a common basis of inflammation and immunopathology. 2. There would be secondary cellular and humoral immunity in the ERMs and the SRMs of PID. Eye Science 1998; 14:35 - 40.
