动物界“睡神”

什么是“神”？其实就是人，只不过他能做到一般人做不到的事情，下面要出场的这几位，虽然不是人，但同样能做到咱们人类力所不能及的事情。

保护“睡神”

人们极少见到睡鼠的最重要原因是它们几乎总在睡大觉。没错，在深秋、冬季以及春季大部分时间里，睡鼠都处于冬眠状态。即使不是在冬眠的季节，它们也用大量时间呼呼大睡。一只睡鼠的寿命是五年，在其中四分之三的时间里都在睡觉。哈哈，堪称“睡神”。

“睡神”齐元琨

齐元琨长得非常结实，他留着小平头，皮肤黑黑的，细长的眼睛，脾气特别好。一次旅游，我和齐元琨成了好朋友。

当睡神听见“啪”的一声

高中的时候，我们班有俩睡神，姑且叫他们睡神甲和睡神乙吧。睡神甲是个女生，主要表现为下课就睡。感觉她就像一个插了电才醒着的人，老师一说下课．相当于把电源给拔了，然后她“整个人生”立马就瘫在了桌子上。

睡神同桌

我的同桌早睡晚起，是传说中的“睡神”。睡神的脾气阴晴不定，没睡醒的时候要是被人烦着了，就暴躁得要命，可要是遇到他清醒而且心情好的时候，他就会乖乖的，绝不轻易招惹别人。就说上星期吧，轮到我们组打扫卫生，大家都想快点干完活，然后去吃饭。可睡神一直处于梦游状态，我们都快干完了，他还在原地没动过。

“睡神”传奇

我们班的阿P外号“睡神”，他嗜睡如命是举世共知的，照阿P的“睡觉哲学”来推断，一年365天天天睡都是有道理的，所以，有同学就别出心裁地称他为“睡神”了。

动物睡神

现代生活压力很大，逢年过节不少人的愿望就是好好睡个懒觉。相比之下，某些动物令人羡慕，它们每天有70％甚至更长的时间在梦乡中度过，堪称“睡神”。

我的同桌是“睡神”

“……啪!”全班同学眼睁睁地看着小包老师那一千度的眼镜儿跌到地上碎成一片片。

睡神的假期

“黑夜女神的后裔，请将我和他的命运联系在一起。”黑暗的森林……跑……一定要跑，哪怕是感到心脏都要跳出来，哪怕是肺部灼烧得再厉害也要赶紧跑。有什么东西在后面追逐着，可怕的、恐怖的、未知的东西，隐藏在无边无际的森林迷雾之中。

“睡神”小琨

以前我跟小琨不太熟，这次一起去旅游，一下就成为了好朋友。小琨长得非常结实，比我大一个月，理个小平头，皮肤黑黑的，细长的眼睛，特别爱笑，脾气也特别好。为什么我要叫他“睡神”呢？听我细细道来。

ADJUSTING EFFECTS OF APPLICATION OF GARLIC PASTE AT SHNQU (神阙 CV8) ON THE CIRCADIAN RHYTHM OF BODY TEMPERATURE INDUCED BY SLEEP DEPRIVATION

Objective To observe the effect of application of garlic paste at Shenque （神阙 CV8） on the circadian rhythm in sleep deprivation young students. Metheds Twenty healthy volunteer young male students from Southern Medical University were randomly divided into three groups： normal group （A）, sleep deprivation group （B） and treatment group （C）. Volunteers in group B and C received 48 h sleep deprivation （SD）, and in the mean time volunteers in group C were treated by garlic paste at Shenque （神阙 CV8）, while those in group A had no any treatment. The body temperature of all the volunteers was detected at 6：00 am, 12：00 am, 6：00 pm and 0：00 am, respectively, after the treatment. Results The mean body temperature values in group A and C both were highest at 6： 00 pm and lowest at 6： 00 am which had a significant difference in each group （P〈0.01）; in group B, the mean body temperature was highest at 0：00 am and lowestat 6：00 am, no significant difference was found between them （P〉0.05）. Results of cosine analysis showed that in subjects of group B the circadian rhythm of body temperature still kept going well after SD, but the peak amplitude and amplitude of vibration were higher than those of group A, and the acrophase of group B was obviously lower than that of group C and A. The 3 indexes of group C were similar to those of group A, denoting that garlic paste application of Shenque （神阙 CV8） could prevent disorders of circadian rhythm of the body temperature. Conclusion The garlic paste application at Shenque （神阙 CV8） can adjust circadian rhythm and accelerate the recovery processes of circadian rhythm in SD young students.

多一把尺子!

同事们建议我读一读学校的教育教学管理格言,或许会有新的认识,从执拗于批评落后学生,教训落后学生的循环中走出来。学校教育教学管理格言中有这样一句吸引了我——多一把尺子衡量孩子,就会多一个优秀的孩子。

Memory consolidation during sleep and adult hippocampal neurogenesis

In anticipation of the massive burden of neurodegenerative disease within super-aged societies, great efforts have been made to utilize neural stem and progenitor cells for regenerative medicine. The capacity of intrinsic neural stem and progenitor cells to regenerate damaged brain tissue remains unclear, due in part to the lack of knowledge about how these newly born neurons integrate into functional circuitry. As sizable integration of adult-born neurons naturally occurs in the dentate gyrus region of the hippocampus, clarifying the mechanisms of this process could provide insights for applying neural stem and progenitor cells in clinical settings. There is convincing evidence of functional correlations between adult-born neurons and memory consolidation and sleep; therefore, we describe some new advances that were left untouched in our recent review.

Clinical observation of auricular needle-embedding therapy for primary insomnia

Objective:To observe the clinical efficacy of auricular needle-embedding therapy for treating primary insomnia.Methods:A total of 63 patients were randomly divided into a conventional acupuncture group and an auricular needleembedding group.The conventional acupuncture group received acupuncture at meridian points,while the auricular needle-embedding group received acupuncture at auricular points.Treatments were given once a day for 6 consecutive days,followed by a 1-day break,as a course of treatment.Both groups were treated for 2 courses.Before treatment,and after 1 course and 2 courses of treatment,the Pittsburgh sleep quality index(PSQI)score was assessed,and the efficacy was evaluated.Results:The cured and markedly effective rate and total effective rate of the auricular needle-embedding group were higher than those of the conventional acupuncture group,but there was no significant difference between the two groups(P>0.05).After 1 course of treatment,the PSQI global score and the scores of subjective sleep quality,sleep latency,sleep duration,habitual sleep efficiency,and daytime dysfunction of both groups decreased compared with those before treatment(P<0.01);there was no statistical significance in comparing the PSQI global score and individual component scores between the two groups(P>0.05).After 2 courses of treatment,the PSQI global score and the scores of sleep latency and habitual sleep efficiency of the auricular needle-embedding group decreased compared with those after 1 course of treatment(P<0.01 or P<0.05),while only the score of sleep latency of the conventional acupuncture group decreased compared with that after 1 course of treatment(P<0.05);the PSQI global score and the scores of subjective sleep quality and sleep latency of the auricular needle-embedding group were lower than those of the conventional acupuncture group(P<0.05).Conclusion:Both therapies can improve insomnia.Compared to conventional acupuncture,auricular needleembedding therapy demonstrates a therapeutic advantage in improving sleep latency and sleep quality,making it worthy of clinical promotion.

时间

我们戏班都靠团长养活，可他外出办事已经一个星期了，仍不见人影。这天，高木打开团长留下的提包，里面竟一无所有。看来团长扔下我们跑了。房租怎么办？大家一时没了主意。我只好代表大伙向客栈求情，说过几天会汇钱来等等，好说歹说，总算可以暂时住下去。然而，每次汇...

Acupuncture combined with ear point taping and pressing for sleep disturbance in 30 children with mental retardation

Objective To observe the therapeutic effect of acupuncture combined with ear point taping and pressing on sleep disturbance of the children with mental retardation. Method Thirty children of mental retardation with sleep disturbance were treated with acupuncture combined with ear point taping and pressing therapy, Sìshénzhēn （四神针）, Nǎosānzhēn （脑三针）, Zhìsānzhēn （智三针）, Nièsānzhēn （颞三针）, Shǒuzhìzhēn （手智针） were selected as main acupoints, and adjunct points were used according to symptoms and syndrome differentiation. For ear point taping and pressing, ěrshénmén （耳神门 MA-TF1）, Pízhìxià （皮质下 MA–AT1）, Jiāogǎn （交感 MA-AH7）, Xīn （心, heart）, Shèn （肾 kidney）, Pí （脾 spleen） were selected. The treatment was given two therapeutic courses, thrice each week, 36 sessions constituted one course. Child Sleep Habit Questionnaire （CSHQ） scale was used for assessment of sleep state before and after the treatment. Results After the treatment, among the 30 cases, 11 cases were markedly effective, 16 cases were effective and 3 cases were failed, the total effective rate was 90.0%; after the treatment, the children had significant improvement in the total time of sleep, the time of going to bed for sleep, sleep habit, sleep behavior, awaking state at night, getting-up state in the morning, sleep state in the daytime and the total score （P0.01, P0.001）. Conclusion Acupuncture combined with ear point taping and pressing therapy has a positive therapeutic effect on sleep disturbance and increases sleep quality in varying degrees in children with mental retardation.

事说

你的同桌是什么类型？ 1．“睡神”型：课表里只有补觉课。 2“吃货”型：上课下课总在吃。 3．“寄生虫”型：不带课本，总是蹭你的用。

Clinical study on acupoint massage in improving cognitive function and sleep quality of elderly patients with hypertension

Objective：To investigate the effects of acupoint massage on cognitive function and sleep quality in elderly patients with hypertension. Methods：A total of 68 elderly patients with hypertension were enrolled, and their ages were all over 60 years old. They were divided into a control group and a treatment group by simple random method, with 34 cases in each group. Patients in the control group were treated by routine psychological health guidance and sleep knowledge education, while patients in the treatment group were treated by acupoint massage on the base of the interventions given to the control group. Both of their treatment courses were 3 months. Pittsburgh sleep quality index （PSQI） scores and mini-mental state examination （MMSE） scores before and after treatment were recorded and compared. Results：Two groups’ PSQI scores before treatment had no significant difference （P〉0.05）. After 3 months of treatment, their PSQI scores were statistically different （P〈0.05）. There was also no between-group statistical difference in MMSE score before treatment （P〉0.05）, but there was a significant difference after treatment （P〈0.05）. Conclusion：Acupoint massage for elderly patients with primary hypertension can improve their sleep quality and enhance their cognitive function, thus it is worthy of being applied in clinical nursing work.

Effect of moxa smoke produced during combustion of Aiye(Folium Artemisiae Argyi) on behavioral changes in mice inhaling the smoke

OBJECTIVE: To evaluate the effects that inhalation of the combustion products of the traditional Chinese herb Aiye(Folium Artemisiae Argyi) has on the central nervous system.METHODS: Forty Kunming mice(half male) were randomly assigned(n = 10/group) to a control group(C) or one of three moxa smoke concentration groups(% opacity): low(L1; 0.4%), medium(M1; 2%), and high(H1; 15%). Mice in the latter three groups were exposed to moxa smoke in a dynamic gas exposure cabinet for 20 min per day for7 days. Mice in control group were placed in the same cabinet without any intervention. For the sleep experiments, another 50 mice were divided into five groups of 10 mice each: a saline-injected control group, L1 + pentobarbital sodium(PS)-injected group, M1+PS group, H1(15%)+PS group,and a positive control group(10 mg/kg, chlorpromazine, p.o.). The weight, general activities, locomotor activities, rotarod performance, sleep duration,and sleeping rate induced by a subthreshold dose of pentobarbital sodium were recorded in the mice,and the composition of moxa smoke was analyzed using headspace gas chromatography(GC-HS).RESULTS: A low concentration of smoke significantly decreased the frequency of locomotor activities and the time for which the mice remaining on the rotarod; however, a high smoke concentration significantly prolonged the pentobarbital-induced sleeping time and sleeping rate.CONCLUSION: The concentration-dependent relaxing effects of moxa smoke on the Central Nervous System(CNS) were confirmed. Moreover, GC-HS analysis showed that the component present in the highest concentration in moxa smoke was eucalyp-tol, an essential oil well recognized for its soothing effects on the CNS. This may therefore be accountable for the sedative effects of moxa smoke.

Anticonvulsant and hypnotic effects of amiodarone

Amiodarone hydrochloride is a potent anti-arrhythmic agent, known as a multiple ion-channel blocker in the heart. Although it has been detected in the rat brain, there are no data related to its central nervous system （CNS） effects. In this study, we evaluated anticonvulsant and hypnotic effects of amiodarone. Convulsions were induced by phentylenetetrazole （PTZ） （100 mg/kg） or caffeine （300 mg/kg） in mice. In both models, amiodarone prolonged both latency period and time to death, and acted as an anticonvulsant drug. It was found to be more effective in the PTZ model than in the caffeine model; none of the animals treated with 150 mg/kg dose amiodarone had died in the PTZ model. For hypnotic effect, sleeping was induced with pentobarbital （35 mg/kg） in rats. Amiodarone dose-dependently increased the sleeping time （677.7%-725.9%）. In the sleeping test, all rats in 200 mg/kg amiodarone group died. In conclusion, anticonvulsant and hypnotic effects of amiodarone have shown the depressant effects on CNS. These effects may be dependent on its pharmacological properties.