In the present work the cosmic ray intensity data recorded with ground-based neutron monitor at Deep River has investigated taking into account the associated interplanetary magnetic field and solar wind plasma data d...In the present work the cosmic ray intensity data recorded with ground-based neutron monitor at Deep River has investigated taking into account the associated interplanetary magnetic field and solar wind plasma data during 1981—1994.A large number of days having abnormally high/low amplitudes for successive number of five or more days as compared to annual average amplitude of diurnal anisotropy have been taken as high/low amplitude anisotropic wave train events(HAE/LAE).The amplitude of the diurnal anisotropy of these events is found to increase on the days of magnetic cloud as compared to the days prior to the event and it found to decrease during the later period of the event as the cloud passes the Earth.The High-Speed Solar Wind Streams(HSSWS)do not play any significant role in causing these types of events. The interplanetary disturbances(magnetic clouds)are also effective in producing cosmic ray decreases.Hαsolar flares have a good positive correlation with both amplitude and direction of the anisotropy for HAEs, whereas PMSs have a good positive correlation with both amplitude and direction of the anisotropy for LAEs. The source responsible for these unusual anisotropic wave trains in CR has been proposed.展开更多
AIM：To evaluate the method of noninvasive transient elastography for assessment of histological stage of liver fibrosis in patients with chronic hepatitis C （CHC）.METHODS： Two hundred and thirty-seven patients wit...AIM：To evaluate the method of noninvasive transient elastography for assessment of histological stage of liver fibrosis in patients with chronic hepatitis C （CHC）.METHODS： Two hundred and thirty-seven patients with CHC were included in this study. Liver biopsy was performed under ultrasonography on 217 of the patients, excluding twenty with clear clinical evidence of liver cirrhosis. Fifty subjects without liver disease were enrolled as a control group （stage 0）. Twentyfive patients with sustained virological response （SVR） to interferon （IFN） therapy were also enrolled. These patients underwent liver biopsy before IFN therapy. Examination of liver stiffness （LS） was performed by elastography.RESISTS： Medians （50% levels） of LS were 4.1 （3.5-4.9）, 6.3 （4.8-8.5）, 8.8 （6.8-12.0）, 14.6 （10.5-18.6）, and 22.2 （15.4-28.0）, respectively, in the fibrosis stages 0-4 （P 〈 0.001）. LS was significantly correlated with four serum fibrosis markers. LS values in patients with SVR were 3.8 （3.5-5.6）, 5.2 （4.4-6.8）, 6.8 （6.1-7.6）, and 6.1 （3.6-7.9）, respectively, in the fibrosis stages 1-4. In all stages, LS for patients with SVR was significantly lower than that for patients who did not undergo IFN therapy. LS was significantly correlated with serum concentrations of hyaluronic acid, type Ⅳ collagen, type Ⅳ collagen 7S, and type Ⅲ procollagen N peptide.CONCLUSION： LS correlated well with the histological stage of fibrosis. Changes in liver fibrosis stage may thus be estimated noninvasively using transient elastography.展开更多
An investigation of the characteristics of flowrate transientswithin slug flow was conducted in a large- scale outdoor testingfacility. The test section consisted of a 378 m long, 7.62 cmdiameter stainless steel pipe....An investigation of the characteristics of flowrate transientswithin slug flow was conducted in a large- scale outdoor testingfacility. The test section consisted of a 378 m long, 7.62 cmdiameter stainless steel pipe. Air and water were used as the testfluids. The response to a change of flowrate of either phase or twophases Was measured using a series of pressure transducers anddifferential pressure transducers. An increase or decrease In gasflowrate caused a pressure overshoot above the value at new steadystate or led to a pressure undershoot To form a temporary stratifiedflow.展开更多
文摘In the present work the cosmic ray intensity data recorded with ground-based neutron monitor at Deep River has investigated taking into account the associated interplanetary magnetic field and solar wind plasma data during 1981—1994.A large number of days having abnormally high/low amplitudes for successive number of five or more days as compared to annual average amplitude of diurnal anisotropy have been taken as high/low amplitude anisotropic wave train events(HAE/LAE).The amplitude of the diurnal anisotropy of these events is found to increase on the days of magnetic cloud as compared to the days prior to the event and it found to decrease during the later period of the event as the cloud passes the Earth.The High-Speed Solar Wind Streams(HSSWS)do not play any significant role in causing these types of events. The interplanetary disturbances(magnetic clouds)are also effective in producing cosmic ray decreases.Hαsolar flares have a good positive correlation with both amplitude and direction of the anisotropy for HAEs, whereas PMSs have a good positive correlation with both amplitude and direction of the anisotropy for LAEs. The source responsible for these unusual anisotropic wave trains in CR has been proposed.
文摘AIM：To evaluate the method of noninvasive transient elastography for assessment of histological stage of liver fibrosis in patients with chronic hepatitis C （CHC）.METHODS： Two hundred and thirty-seven patients with CHC were included in this study. Liver biopsy was performed under ultrasonography on 217 of the patients, excluding twenty with clear clinical evidence of liver cirrhosis. Fifty subjects without liver disease were enrolled as a control group （stage 0）. Twentyfive patients with sustained virological response （SVR） to interferon （IFN） therapy were also enrolled. These patients underwent liver biopsy before IFN therapy. Examination of liver stiffness （LS） was performed by elastography.RESISTS： Medians （50% levels） of LS were 4.1 （3.5-4.9）, 6.3 （4.8-8.5）, 8.8 （6.8-12.0）, 14.6 （10.5-18.6）, and 22.2 （15.4-28.0）, respectively, in the fibrosis stages 0-4 （P 〈 0.001）. LS was significantly correlated with four serum fibrosis markers. LS values in patients with SVR were 3.8 （3.5-5.6）, 5.2 （4.4-6.8）, 6.8 （6.1-7.6）, and 6.1 （3.6-7.9）, respectively, in the fibrosis stages 1-4. In all stages, LS for patients with SVR was significantly lower than that for patients who did not undergo IFN therapy. LS was significantly correlated with serum concentrations of hyaluronic acid, type Ⅳ collagen, type Ⅳ collagen 7S, and type Ⅲ procollagen N peptide.CONCLUSION： LS correlated well with the histological stage of fibrosis. Changes in liver fibrosis stage may thus be estimated noninvasively using transient elastography.
基金Supported by the National Natural Science Foundation of China (No.59995462) and the National Science Foundation of China for distinguished Young Scientists (No. 59725616).
文摘An investigation of the characteristics of flowrate transientswithin slug flow was conducted in a large- scale outdoor testingfacility. The test section consisted of a 378 m long, 7.62 cmdiameter stainless steel pipe. Air and water were used as the testfluids. The response to a change of flowrate of either phase or twophases Was measured using a series of pressure transducers anddifferential pressure transducers. An increase or decrease In gasflowrate caused a pressure overshoot above the value at new steadystate or led to a pressure undershoot To form a temporary stratifiedflow.
