Objective: The aim of this study was to determine differing reactions of the l eft and right eyes with regard to pupillary light reflex (PLR) parameters. Metho ds: All together 90 healthy subjects were included. In th...Objective: The aim of this study was to determine differing reactions of the l eft and right eyes with regard to pupillary light reflex (PLR) parameters. Metho ds: All together 90 healthy subjects were included. In the first test series, 34 subjects were investigated on both eyes (left eye was tested first, three tests per day and one reliability test). In the second test series, 32 subjects were studied while changing the beginning side. In the last test series, 29 subjects were investigated 12 times each within 1 h (beginning side changed, without spok en advice).Infrared pupillometry was used to study pupil diameter, latency time, relative amplitude, contraction/dilation velocity, and pupil redilation time. R esults: The study demonstrated significant differences of PLR parameters between both eyes. In contrast to the pupil diameter of the left eye the papasympatheti cally dominated right eye was not influenced by vocal instructions or by changin g the beginning side. Conclusions: PLR parameters might indicate functional late ralization of autonomic functionin the central nervous system. High sensitivity of the procedure(arousal due to spoken advice, time of day) is advantageous for various psychophysiological investigations. Significance:Differences between bot h eyes might point towards cortical lateralization of central autonomic function .展开更多
建立了一种基于图像处理的快速瞳孔直径检测算法,运用此算法提取了反映阿片类药物成瘾人员与正常人对瞳孔光反射变化差异的3个特征值:绝对收缩幅度(absolute amplitude of contraction,AAC)、相对收缩幅度(relative amplitude of contra...建立了一种基于图像处理的快速瞳孔直径检测算法,运用此算法提取了反映阿片类药物成瘾人员与正常人对瞳孔光反射变化差异的3个特征值:绝对收缩幅度(absolute amplitude of contraction,AAC)、相对收缩幅度(relative amplitude of contraction,RAC)和收缩斜率(SCV,slope of contraction velocity);分别研究了成瘾、性别、近视、年龄、睡眠剥夺等因素对于这3个特征值的影响。不同性别、近视人员、睡眠剥夺人员与正常人之间的3个特征值均无显著差异,成瘾人员与之对比均显著减小。老年人相对于正常青年人,3个特征值都明显减小;与成瘾人员相比,仅在RAC值上有显著差异。结果表明,阿片类药物成瘾人员除了与正常人外,也与其他具有潜在影响瞳孔变化因素的非阿片成瘾人员在瞳孔对光反射的特征值上具有显著差异。该研究的实验数据为进一步建立基于检测瞳孔对光反射其直径发生变化的方法来快速、非接触地鉴别出阿片类药物成瘾人员提供了可靠的依据。展开更多
Background: Relative afferent pupillary defects are typically related to ipsil ateral lesions within the anterior visual pathways. Objective: To describe a pat ient who had a workup for headache and was found to have ...Background: Relative afferent pupillary defects are typically related to ipsil ateral lesions within the anterior visual pathways. Objective: To describe a pat ient who had a workup for headache and was found to have an isolated left relati ve afferent pupillary defect without any other neurological findings. Design: We review the neuroanatomy of the pupillary light reflex pathway and emphasize the nasotemporal bias of decussating fiber projections, which accounts for the rela tive afferent pupillary defect contralateral to the described lesion. Result: Ma gnetic resonance imaging of the brain revealed a pineal tumor compressing the ri ght rostral midbrain. Conclusion: While rare, a relative afferent pupillary defe ct can occasionally occur secondary to lesions in the postchiasmal pathways. In these circumstances, the pupillary defect will be observed to be contralateral t o the side of the lesion.展开更多
文摘Objective: The aim of this study was to determine differing reactions of the l eft and right eyes with regard to pupillary light reflex (PLR) parameters. Metho ds: All together 90 healthy subjects were included. In the first test series, 34 subjects were investigated on both eyes (left eye was tested first, three tests per day and one reliability test). In the second test series, 32 subjects were studied while changing the beginning side. In the last test series, 29 subjects were investigated 12 times each within 1 h (beginning side changed, without spok en advice).Infrared pupillometry was used to study pupil diameter, latency time, relative amplitude, contraction/dilation velocity, and pupil redilation time. R esults: The study demonstrated significant differences of PLR parameters between both eyes. In contrast to the pupil diameter of the left eye the papasympatheti cally dominated right eye was not influenced by vocal instructions or by changin g the beginning side. Conclusions: PLR parameters might indicate functional late ralization of autonomic functionin the central nervous system. High sensitivity of the procedure(arousal due to spoken advice, time of day) is advantageous for various psychophysiological investigations. Significance:Differences between bot h eyes might point towards cortical lateralization of central autonomic function .
文摘建立了一种基于图像处理的快速瞳孔直径检测算法,运用此算法提取了反映阿片类药物成瘾人员与正常人对瞳孔光反射变化差异的3个特征值:绝对收缩幅度(absolute amplitude of contraction,AAC)、相对收缩幅度(relative amplitude of contraction,RAC)和收缩斜率(SCV,slope of contraction velocity);分别研究了成瘾、性别、近视、年龄、睡眠剥夺等因素对于这3个特征值的影响。不同性别、近视人员、睡眠剥夺人员与正常人之间的3个特征值均无显著差异,成瘾人员与之对比均显著减小。老年人相对于正常青年人,3个特征值都明显减小;与成瘾人员相比,仅在RAC值上有显著差异。结果表明,阿片类药物成瘾人员除了与正常人外,也与其他具有潜在影响瞳孔变化因素的非阿片成瘾人员在瞳孔对光反射的特征值上具有显著差异。该研究的实验数据为进一步建立基于检测瞳孔对光反射其直径发生变化的方法来快速、非接触地鉴别出阿片类药物成瘾人员提供了可靠的依据。
文摘Background: Relative afferent pupillary defects are typically related to ipsil ateral lesions within the anterior visual pathways. Objective: To describe a pat ient who had a workup for headache and was found to have an isolated left relati ve afferent pupillary defect without any other neurological findings. Design: We review the neuroanatomy of the pupillary light reflex pathway and emphasize the nasotemporal bias of decussating fiber projections, which accounts for the rela tive afferent pupillary defect contralateral to the described lesion. Result: Ma gnetic resonance imaging of the brain revealed a pineal tumor compressing the ri ght rostral midbrain. Conclusion: While rare, a relative afferent pupillary defe ct can occasionally occur secondary to lesions in the postchiasmal pathways. In these circumstances, the pupillary defect will be observed to be contralateral t o the side of the lesion.
