Creatinine, urea, uric acid, water and electrolytes renal handling in the healthy oldest old

Renal physiology in the healthy oldest old has the fol-lowing characteristics, in comparison with the renal physiology in the young： a reduced creatinine clear-ance, tubular pattern of creatinine back-fltration, pre-served proximal tubule sodium reabsorption and uric acid secretion, reduced sodium reabsorption in the thick ascending loop of Henle, reduced free water clear-ance, increased urea excretion, presence of medulla hypotonicity, reduced urinary dilution and concentra-tion capabilities, and fnally a reduced collecting tubules response to furosemide which expresses a reduced potassium excretion in this segment due to a sort of aldosterone resistance. All physiological changes of the aged kidney are the same in both genders.

Effects of Equilibrium Therapy Exercise on Dysmenorrhea in Nursing Students

The purpose of this pre-experimental research （one-group pretest-posttest design） was to study the ettects ot the 4 Basics Exercise Model on dysmenorrhea for structural equilibrium changes in nursing students at Phachomklao College of Nursing, Phetchaburi Province, who were divided the 4 Basics Exercise Model for dysmenorrhea into pre- and post-test experimental groups. The sample group was composed of 31 persons, using the 4 Basics Exercise Model over three months for 30 minutes per day on Sundays, Tuesdays, and Thursdays. Data were collected on personal information, dysmenorrhea pain scores, and satisfaction in the 4 Basics Exercise Model for dysmenorrhea records. According to the research findings, the level of dysmenorrhea pain was significantly decreased in the experimental group for one, two, and three months post-exercise. In addition, the comparison of decreases in the dysmenorrhea pain of experimental group was significantly different at two and three months post-exercise at .01. The exception was at one month post-exercise when there was no statistically significant difference. According to the findings of the study, the 4 Basics Exercise Model for dysmenorrhea effectively decreased dysmenorrhea and the duration of menstrual periods with improving signs of menstruation. Therefore, nurses who provide gynecological care should learn and have knowledge regarding the 4 Basics Exercise Model to help relieve menstrual pain.

Investigation of TCM constitution in 138 patients with primary biliary cholangitis (PBC)

OBJECTIVE: To analyze the distribution and characteristics of TCM constitution in patients with primary biliary cholangitis(PBC). METHODS: 138 PBC patients who met the inclusion criteria were divided into 3 groups according to the stage of disease development: group A(group of basic normal), group B(group of symptom stage) and group C(group of decompensation stage). Each group collected 46 cases, and every patient was reexamined, which included blood routine examination, liver function test, image ultrasound examination, autoantibody examination and immunoglobulin test. Then, the patients' clinical symptoms were observed and recorded, and their constitution of traditional Chinese medicine were classified. RESULTS:(1) For 138 patients with PBC, their TCM constitution was characterized by biased constitution, among which constitution of Qi stagnation(19.57%) was the majority, which was followed by constitution of Qi asthenia(15.94%), constitution of Yin asthenia(15.94%) and constitution of damp-heat(14.49%). There was no significant correlation between the type of constitution and the age of onset(P>0.05).(2) The constitution types of group A and B were mainly constitution of Qi stagnation, constitution of Qi asthenia and constitution of damp-heat, while group C was mainly composed of constitution of blood stasis, constitution of Yin asthenia and constitution of Yang asthenia.(3) The highest positive rate of autoantibodies in patients with PBC was constitution of Qi stagnation, which was followed by constitution of damp-heat, constitution of Yin asthenia and constitution of Qi asthenia. The most abnormal liver function and immunoglobulin were constitution of Qi stagnation, which was followed by constitution of Qi asthenia, constitution of Yin asthenia, constitution of damp-heat.CONCLUSION: Constitution of Qi stagnation, constitution of Qi asthenia, constitution of damp-heat and constitution of Yin asthenia were the susceptible constitutions of PBC patients.

Mechanism of sex hormone level in biological clock disorder induced acne and analysis of TCM Pathogenesis

Acne vulgaris is a common chronic inflammatory disease of pilosebaceous units. And sex hormone level disorder has became a hot research topic in the pathogenesis of acne. Studies show that the biological clock disorder can result in the disorder of sex hormone levels which causes or aggravates acne. Biological clock disorder coincides naturally with "sleep rhythm disorder" in Traditional Chinese Medicine(TCM). In this paper, we will discuss the modern medical mechanism of the biological clock disorder resulting in acne from the angle of sex hormones, and analyze the TCM pathogenesis of the disease caused by the disorder of the biological clock.

The progress of treatment of children＇s psoriasis

Psoriasis is a chronic recurrent inflammatory skin disease, with erythema based on silver-white scales as the main clinical features. The incidence of psoriasis in children has gradually increased, and the clinical manifestations are not typical. Moreover, the drug sensitivity and tolerance of children are different with that of adults. This article reviews the treatment of children's psoriasis in China and abroad.

糖尿病病友不能忽视的方方面面

我是已有二十年病史的糖尿病患者，走过了不少艰难、曲折、痛苦的道路。但通过长期学习糖尿病的有关知识，并善于积累和总结，终于从失败中爬起来。如今我已66岁，心脏还很健康，眼底非常正常，血压长期稳定在105～115／70～75mmHg。下面是我多年积累的成功经验，希望能给病友们一些启发。