The structures of the space switching and the wavelength switching optical cross connect (OXC) nodes which are based on the arrayed waveguide grating (AWG) multiplexer are analyzed.By the matrix transformation relatio...The structures of the space switching and the wavelength switching optical cross connect (OXC) nodes which are based on the arrayed waveguide grating (AWG) multiplexer are analyzed.By the matrix transformation relation between the input and output wavelengths of the AWG multiplexer, the wavelength transmission routings of the space switching and wavelength switching OXC nodes are determined.展开更多
A new method for analyzing high-speed circuit systems is presented. The method adds transmission line end currents to the circuit variables of the classical modified nodal approach. Then the matrix equation describing...A new method for analyzing high-speed circuit systems is presented. The method adds transmission line end currents to the circuit variables of the classical modified nodal approach. Then the matrix equation describing high-speed circuit system can be formulated directly and analyzed conveniently for its normative form. A time-domain analysis method for transmission lines is also introduced. The two methods are combined together to efficiently analyze high-speed circuit systems having general transmission lines. Numerical experiment is presented and the results are compared with that calculated by Hspice.展开更多
Aiming at the problem that some existing traffic flow prediction models are only for a single road segment and the model input data are not pre-processed,a heuristic threshold algorithm is used to de-noise the origina...Aiming at the problem that some existing traffic flow prediction models are only for a single road segment and the model input data are not pre-processed,a heuristic threshold algorithm is used to de-noise the original traffic flow data after wavelet decomposition.The correlation coefficients of road traffic flow data are calculated and the data compression matrix of road traffic flow is constructed.Data de-noising minimizes the interference of data to the model,while the correlation analysis of road network data realizes the prediction at the road network level.Utilizing the advantages of long short term memory(LSTM)network in time series data processing,the compression matrix is input into the constructed LSTM model for short-term traffic flow prediction.The LSTM-1 and LSTM-2 models were respectively trained by de-noising processed data and original data.Through simulation experiments,different prediction times were set,and the prediction results of the prediction model proposed in this paper were compared with those of other methods.It is found that the accuracy of the LSTM-2 model proposed in this paper increases by 10.278%on average compared with other prediction methods,and the prediction accuracy reaches 95.58%,which proves that the short-term traffic flow prediction method proposed in this paper is efficient.展开更多
This paper presents an analog circuit built-in-test (BIT) structure based on boundary scan and realizes the BI'I. It predigests the test process and improves the test precision by taking the rectangular pulse as st...This paper presents an analog circuit built-in-test (BIT) structure based on boundary scan and realizes the BI'I. It predigests the test process and improves the test precision by taking the rectangular pulse as stimulator and analog switch as auxiliary bridge. The experiment of uA741 shows that the design is feasible. Compared with the traditional test method, it is better regarding reliability and measurability of the analog circuit system.展开更多
Shape coexistence and band structure near yrast line of the Z = N doubly magic nucleus 40Ca have been investigated by the configuration-dependent cranked Nilsson-Strutinsky approach. The observed normal deformed and ...Shape coexistence and band structure near yrast line of the Z = N doubly magic nucleus 40Ca have been investigated by the configuration-dependent cranked Nilsson-Strutinsky approach. The observed normal deformed and superdeformed bands are explained and the terminating states are confirmed by the calculations. The transition quadrupole moment Qt of the calculated superdeformed band is in good agreement with the observed one at high spin. There is shape coexistence within the same configuration. Possible normal deformed and superdeformed bands with rotation around the intermediate axis in several interesting configurations of40Ca are discussed. Possible favored superdeformed band terminations in 38Ca and 38Ar are predicted. The experimental results in 38Ar are discussed simply.展开更多
To achieve sparse sampling on a coded ultrasonic signal,the finite rate of innovation(FRI)sparse sampling technique is proposed on a binary frequency-coded(BFC)ultrasonic signal.A framework of FRI-based sparse samplin...To achieve sparse sampling on a coded ultrasonic signal,the finite rate of innovation(FRI)sparse sampling technique is proposed on a binary frequency-coded(BFC)ultrasonic signal.A framework of FRI-based sparse sampling for an ultrasonic signal pulse is presented.Differences between the pulse and the coded ultrasonic signal are analyzed,and a response mathematical model of the coded ultrasonic signal is established.A time-domain transform algorithm,called the high-order moment method,is applied to obtain a pulse stream signal to assist BFC ultrasonic signal sparse sampling.A sampling of the output signal with a uniform interval is then performed after modulating the pulse stream signal by a sampling kernel.FRI-based sparse sampling is performed using a self-made circuit on an aluminum alloy sample.Experimental results show that the sampling rate reduces to 0.5 MHz,which is at least 12.8 MHz in the Nyquist sampling mode.The echo peak amplitude and the time of flight are estimated from the sparse sampling data with maximum errors of 9.324%and 0.031%,respectively.This research can provide a theoretical basis and practical application reference for reducing the sampling rate and data volume in coded ultrasonic testing.展开更多
The hybrid routing protocol has received more attention recently than the proactive and the reactive, especially for large-scale and highly dynamic connection,in mobile ad hoc network. A crucial reason is that zone-la...The hybrid routing protocol has received more attention recently than the proactive and the reactive, especially for large-scale and highly dynamic connection,in mobile ad hoc network. A crucial reason is that zone-layered is being utilized in the complex systems.A hybrid routing algorithm which is layered zone based on adjacency connection(LZBAC) is put forward under the background of a few members in network with steady position and link. The algorithm modifies storage structure of nodes and improves routing mechanism. The theoretical analysis and simulation testing testify that the algorithm costs shorter time of route finding and less delay than others.展开更多
Symbolic analysis has many applications in the design of analog circuits. Existing approaches rely on two forms of symbolic-expression representation: expanded sum-of-product form and arbitrarily nested form. Expanded...Symbolic analysis has many applications in the design of analog circuits. Existing approaches rely on two forms of symbolic-expression representation: expanded sum-of-product form and arbitrarily nested form. Expanded form suffers the problem that the number of product terms grows exponentially with the size of a circuit. Nested form is neither canonical nor amenable to symbolic manipulation. In this paper, we present a new approach to exact and canonical symbolic analysis by exploiting the sparsity and sharing of product terms. This algorithm, called totally coded method (TCM), consists of representing the symbolic determinant of a circuit matrix by code series and performing symbolic analysis by code manipulation. We describe an efficient code-ordering heuristic and prove that it is optimum for ladder-structured circuits. For practical analog circuits, TCM not only covers all advantages of the algorithm via determinant decision diagrams (DDD) but is more simple and efficient than DDD method.展开更多
The behavior of matrix converter(MC) drive systems under the condition of MC short-circuit faults is comprehensively investigated. Two isolation strategies using semiconductors and high speed fuses(HSFs) for MC short-...The behavior of matrix converter(MC) drive systems under the condition of MC short-circuit faults is comprehensively investigated. Two isolation strategies using semiconductors and high speed fuses(HSFs) for MC short-circuit faults are examined and their performances are compared. The behavior of MC drive systems during the fuse action time under different operating conditions is explored. The feasibility of fault-tolerant operation during the fuse action time is also studied. The basic selection laws for the HSFs and the requirements for the passive components of the MC drive system from the point view of short-circuit faults are also discussed. Simulation results are used to demonstrate the feasibility of the proposed isolation strategies.展开更多
A traffic matrix is a necessary parameter fornetwork management functions,and itsupplies a flow-level view of a largescale IP-over-WDM backbone network.This paper studies the problem of traffic matrix estimationand pr...A traffic matrix is a necessary parameter fornetwork management functions,and itsupplies a flow-level view of a largescale IP-over-WDM backbone network.This paper studies the problem of traffic matrix estimationand proposes an exact traffic matrix estimation approach based on network tomography techniques.The traditional network tomography model is extended to make it compatible with compressive sensing constraints.First,a stochastic perturbation is introduced in the traditional network tomography inference model.Then,an algorithm is proposed to achieve additional optical link observations via optical bypass techniques.The obtained optical link observations are used as extensions for the perturbed network tomography model to ensure that the synthetic model can meetcompressive sensing constraints.Finally,the traffic matrix is estimated from the synthetic model by means of a compressive sensing recovery algorithm.展开更多
Circuits with switched current are described by an admittance matrix and seeking current transfers then means calculating the ratio of algebraic supplements of this matrix. As there are also graph methods of circuit a...Circuits with switched current are described by an admittance matrix and seeking current transfers then means calculating the ratio of algebraic supplements of this matrix. As there are also graph methods of circuit analysis in addition to algebraic methods, it is clearly possible in theory to carry out an analysis of the whole switched circuit in two-phase switching exclusively by the graph method as well. For this purpose it is possible to plot a Mason graph of a circuit, use transformation graphs to reduce Mason graphs for all the four phases of switching, and then plot a summary graph from the transformed graphs obtained this way. First the author draws nodes and possible branches, obtained by transformation graphs for transfers of EE (even-even) and OO (odd-odd) phases. In the next step, branches obtained by transformation graphs for EO and OE phase are drawn between these nodes, while their resulting transfer is 1 multiplied by z^1/2. This summary graph is extended by two branches from input node and to output node, the extended graph can then be interpreted by the Mason's relation to provide transparent current transfers. Therefore it is not necessary to compose a sum admittance matrix and to express this consequently in numbers, and so it is possible to reach the final result in a graphical way.展开更多
With the increasing necessities for reliable printed circuit board(PCB) product, there has been a considerable demand for high speed and high precision vision positioning system. To locate a rectangular lead component...With the increasing necessities for reliable printed circuit board(PCB) product, there has been a considerable demand for high speed and high precision vision positioning system. To locate a rectangular lead component with high accuracy and reliability, a new visual positioning method was introduced. Considering the limitations of Ghosal sub-pixel edge detection algorithm, an improved algorithm was proposed, in which Harris corner features were used to coarsely detect the edge points and Zernike moments were adopted to accurately detect the edge points. Besides, two formulas were developed to determine the edge intersections whose sub-pixel coordinates were calculated with bilinear interpolation and conjugate gradient method. The last experimental results show that the proposed method can detect the deflection and offset, and the detection errors are less than 0.04° and 0.02 pixels.展开更多
This work proposes a map-based control method to improve a vehicle's lateral stability, and the performance of the proposed method is compared with that of the conventional model-referenced control method. Model-r...This work proposes a map-based control method to improve a vehicle's lateral stability, and the performance of the proposed method is compared with that of the conventional model-referenced control method. Model-referenced control uses the sliding mode method to determine the compensated yaw moment; in contrast, the proposed map-based control uses the compensated yaw moment map acquired by vehicle stability analysis. The vehicle stability region is calculated by a topological method based on the trajectory reversal method. A 2-DOF vehicle model and Pacejka's tire model are used to evaluate the proposed map-based control method. The properties of model-referenced control and map-based control are compared under various road conditions and driving inputs. Model-referenced control uses a control input to satisfy the linear reference model, and it generates unnecessary tire lateral forces that may lead to worse performance than an uncontrolled vehicle with step steering input on a road with a low friction coefficient. However, map-based control determines a compensated yaw moment to maintain the vehicle within the stability region,so the typical responses of vehicle enable to converge rapidly. The simulation results with sine and step steering show that map-based control provides better the tracking responsibility and control performance than model-referenced control.展开更多
VFT (variable frequency transformer) has been recently used as art alternative to HVDC (high voltage direct current) to control power flow between asynchronous networks. VFT consumes less reactive power than a bac...VFT (variable frequency transformer) has been recently used as art alternative to HVDC (high voltage direct current) to control power flow between asynchronous networks. VFT consumes less reactive power than a back-to-back HVDC system, provides faster initial transient recovery, and has better natural damping capability. VFT is simply a DFIM (doubly-fed induction machine) where the machine torque controls the power flow from stator to rotor and vice versa. The main disadvantage of this VFT is the slip rings and brushes required for the rotor circuit, especially in bulk power transmission. The BDFM (brushless doubly-fed machine) with nested cage rotor machine is proved to be a comparable alternative to conventional DFIM in many applications with the advantage that all windings being in the stator frame with fixed output terminals. In this paper, the BDFM is used as a BVFT (brushless variable frequency transformer). A prototype machine is designed and simulated to verify the system validity.展开更多
AIM:To clarify the role of activated Notch2 in the invasiveness of gastric cancer.METHODS:To investigate the invasiveness of silencing Notch2 gene expression,we established a Notch2small interfering RNA(siRNA) tra...AIM:To clarify the role of activated Notch2 in the invasiveness of gastric cancer.METHODS:To investigate the invasiveness of silencing Notch2 gene expression,we established a Notch2small interfering RNA(siRNA) transfected cell line using the MKN-45 gastric cancer cell line.After the successful transfection confirmed by real-time reverse transcription-polymerase chain reaction(RT-PCR) and Western blotting,migration and invasion assays were employed to evaluate the aggressiveness of the gastric cancer.RT-PCR and Western blottings were employed to confirm the down-regulation of Notch2 and to evaluate the expression of epithelial mesenchymal transition-related gene matrix metallopeptidase 9(MMP9),Akt,p-Akt.To confirm the relationship between PI3KAkt and MMP9,the PI3K inhibitor LY294002 was used to treat MKN-45 cells.RESULTS:Notch2 expression was dramatically decreased after Notch2 siRNA transfection(100.00% ± 9.74% vs 11.61% ± 3.85%,P 〈 0.01 by qRT-PCR).There was also a marked reduction of Notch target gene Hes1(100.00% ± 4.74% vs 61.61% ± 3.58%,P 〈 0.05) at the mRNA,indicating an inhibition of Notch signaling.Inhibition of Notch signaling was also confirmed by the marked reduction of Notch2 intracellular domain at the protein levels(100.00% ± 9.74% vs 65.61% ± 7.58%,P 〈 0.05).Down-regulation of Notch2 by siRNA enhanced tumor cell invasion(100.00% ± 21.64% vs 162.22% ± 16.84%,P 〈 0.05) and expression of MMP9(1.56 fold,P 〈 0.05),and activated the pro-MMP9 protein to its active form(1.48 fold,P 〈 0.05).There was no significant difference in the protein levels of Akt between the two groups(100.00% ± 10.87% vs 96.61% ± 7.33%,P 〉 0.05),while down-regulation of Notch2 elevated p-Akt expression(100.00% ± 9.87% vs 154.61% ± 13.10%,P 〈 0.05).Furthermore,p-Akt and MMP9 was down-regulated in response to the inhibitor LY294002(p-Akt 100.00% ± 8.87% vs 58.27% ± 5.01%,P 〈 0.05;MMP9 100.00% ± 9.17% vs 50.03% ± 4.88%,P 〈 0.05).CONCLUSION:Notch2 may negatively regulate cell invasion by inhibiting the PI3K-Akt signaling pathway展开更多
基金NationalKeyLabofBroadBandFiberTransmissionandCommunicatonSystemTechnology ElectronicUniversityofScienceandTechnology China
文摘The structures of the space switching and the wavelength switching optical cross connect (OXC) nodes which are based on the arrayed waveguide grating (AWG) multiplexer are analyzed.By the matrix transformation relation between the input and output wavelengths of the AWG multiplexer, the wavelength transmission routings of the space switching and wavelength switching OXC nodes are determined.
文摘A new method for analyzing high-speed circuit systems is presented. The method adds transmission line end currents to the circuit variables of the classical modified nodal approach. Then the matrix equation describing high-speed circuit system can be formulated directly and analyzed conveniently for its normative form. A time-domain analysis method for transmission lines is also introduced. The two methods are combined together to efficiently analyze high-speed circuit systems having general transmission lines. Numerical experiment is presented and the results are compared with that calculated by Hspice.
基金National Natural Science Foundation of China(No.71961016)Planning Fund for the Humanities and Social Sciences of the Ministry of Education(Nos.15XJAZH002,18YJAZH148)Natural Science Foundation of Gansu Province(No.18JR3RA125)。
文摘Aiming at the problem that some existing traffic flow prediction models are only for a single road segment and the model input data are not pre-processed,a heuristic threshold algorithm is used to de-noise the original traffic flow data after wavelet decomposition.The correlation coefficients of road traffic flow data are calculated and the data compression matrix of road traffic flow is constructed.Data de-noising minimizes the interference of data to the model,while the correlation analysis of road network data realizes the prediction at the road network level.Utilizing the advantages of long short term memory(LSTM)network in time series data processing,the compression matrix is input into the constructed LSTM model for short-term traffic flow prediction.The LSTM-1 and LSTM-2 models were respectively trained by de-noising processed data and original data.Through simulation experiments,different prediction times were set,and the prediction results of the prediction model proposed in this paper were compared with those of other methods.It is found that the accuracy of the LSTM-2 model proposed in this paper increases by 10.278%on average compared with other prediction methods,and the prediction accuracy reaches 95.58%,which proves that the short-term traffic flow prediction method proposed in this paper is efficient.
文摘This paper presents an analog circuit built-in-test (BIT) structure based on boundary scan and realizes the BI'I. It predigests the test process and improves the test precision by taking the rectangular pulse as stimulator and analog switch as auxiliary bridge. The experiment of uA741 shows that the design is feasible. Compared with the traditional test method, it is better regarding reliability and measurability of the analog circuit system.
文摘Shape coexistence and band structure near yrast line of the Z = N doubly magic nucleus 40Ca have been investigated by the configuration-dependent cranked Nilsson-Strutinsky approach. The observed normal deformed and superdeformed bands are explained and the terminating states are confirmed by the calculations. The transition quadrupole moment Qt of the calculated superdeformed band is in good agreement with the observed one at high spin. There is shape coexistence within the same configuration. Possible normal deformed and superdeformed bands with rotation around the intermediate axis in several interesting configurations of40Ca are discussed. Possible favored superdeformed band terminations in 38Ca and 38Ar are predicted. The experimental results in 38Ar are discussed simply.
基金The National Natural Science Foundation of China (No.51375217)。
文摘To achieve sparse sampling on a coded ultrasonic signal,the finite rate of innovation(FRI)sparse sampling technique is proposed on a binary frequency-coded(BFC)ultrasonic signal.A framework of FRI-based sparse sampling for an ultrasonic signal pulse is presented.Differences between the pulse and the coded ultrasonic signal are analyzed,and a response mathematical model of the coded ultrasonic signal is established.A time-domain transform algorithm,called the high-order moment method,is applied to obtain a pulse stream signal to assist BFC ultrasonic signal sparse sampling.A sampling of the output signal with a uniform interval is then performed after modulating the pulse stream signal by a sampling kernel.FRI-based sparse sampling is performed using a self-made circuit on an aluminum alloy sample.Experimental results show that the sampling rate reduces to 0.5 MHz,which is at least 12.8 MHz in the Nyquist sampling mode.The echo peak amplitude and the time of flight are estimated from the sparse sampling data with maximum errors of 9.324%and 0.031%,respectively.This research can provide a theoretical basis and practical application reference for reducing the sampling rate and data volume in coded ultrasonic testing.
基金This work was supported in part by Research fund from Educational Committee of China (No104086)
文摘The hybrid routing protocol has received more attention recently than the proactive and the reactive, especially for large-scale and highly dynamic connection,in mobile ad hoc network. A crucial reason is that zone-layered is being utilized in the complex systems.A hybrid routing algorithm which is layered zone based on adjacency connection(LZBAC) is put forward under the background of a few members in network with steady position and link. The algorithm modifies storage structure of nodes and improves routing mechanism. The theoretical analysis and simulation testing testify that the algorithm costs shorter time of route finding and less delay than others.
文摘Symbolic analysis has many applications in the design of analog circuits. Existing approaches rely on two forms of symbolic-expression representation: expanded sum-of-product form and arbitrarily nested form. Expanded form suffers the problem that the number of product terms grows exponentially with the size of a circuit. Nested form is neither canonical nor amenable to symbolic manipulation. In this paper, we present a new approach to exact and canonical symbolic analysis by exploiting the sparsity and sharing of product terms. This algorithm, called totally coded method (TCM), consists of representing the symbolic determinant of a circuit matrix by code series and performing symbolic analysis by code manipulation. We describe an efficient code-ordering heuristic and prove that it is optimum for ladder-structured circuits. For practical analog circuits, TCM not only covers all advantages of the algorithm via determinant decision diagrams (DDD) but is more simple and efficient than DDD method.
基金Project(50807002) supported by the National Natural Science Foundation of ChinaProject(SKLD10KM05) supported by Opening Fund of State Key Laboratory of Power System and Generation EquipmentsProject(201206025007) supported by the National Scholarship Fund,China
文摘The behavior of matrix converter(MC) drive systems under the condition of MC short-circuit faults is comprehensively investigated. Two isolation strategies using semiconductors and high speed fuses(HSFs) for MC short-circuit faults are examined and their performances are compared. The behavior of MC drive systems during the fuse action time under different operating conditions is explored. The feasibility of fault-tolerant operation during the fuse action time is also studied. The basic selection laws for the HSFs and the requirements for the passive components of the MC drive system from the point view of short-circuit faults are also discussed. Simulation results are used to demonstrate the feasibility of the proposed isolation strategies.
基金supported in part by the National Natural Science Foundation of China(Nos.61571104,61071124,61501105)the General Project of Scientific Research of the Education Department of Liaoning Province(No.L20150174)+2 种基金the Program for New Century Excellent Talents in University(No.NCET-11-0075)the Fundamental Research Funds for the Central Universities(Nos.N150402003,N120804004,N130504003,N150404018)the State Scholarship Fund(201208210013)
文摘A traffic matrix is a necessary parameter fornetwork management functions,and itsupplies a flow-level view of a largescale IP-over-WDM backbone network.This paper studies the problem of traffic matrix estimationand proposes an exact traffic matrix estimation approach based on network tomography techniques.The traditional network tomography model is extended to make it compatible with compressive sensing constraints.First,a stochastic perturbation is introduced in the traditional network tomography inference model.Then,an algorithm is proposed to achieve additional optical link observations via optical bypass techniques.The obtained optical link observations are used as extensions for the perturbed network tomography model to ensure that the synthetic model can meetcompressive sensing constraints.Finally,the traffic matrix is estimated from the synthetic model by means of a compressive sensing recovery algorithm.
文摘Circuits with switched current are described by an admittance matrix and seeking current transfers then means calculating the ratio of algebraic supplements of this matrix. As there are also graph methods of circuit analysis in addition to algebraic methods, it is clearly possible in theory to carry out an analysis of the whole switched circuit in two-phase switching exclusively by the graph method as well. For this purpose it is possible to plot a Mason graph of a circuit, use transformation graphs to reduce Mason graphs for all the four phases of switching, and then plot a summary graph from the transformed graphs obtained this way. First the author draws nodes and possible branches, obtained by transformation graphs for transfers of EE (even-even) and OO (odd-odd) phases. In the next step, branches obtained by transformation graphs for EO and OE phase are drawn between these nodes, while their resulting transfer is 1 multiplied by z^1/2. This summary graph is extended by two branches from input node and to output node, the extended graph can then be interpreted by the Mason's relation to provide transparent current transfers. Therefore it is not necessary to compose a sum admittance matrix and to express this consequently in numbers, and so it is possible to reach the final result in a graphical way.
基金Project(51175242)supported by the National Natural Science Foundation of ChinaProject(BA2012031)supported by the Jiangsu Province Science and Technology Foundation of China
文摘With the increasing necessities for reliable printed circuit board(PCB) product, there has been a considerable demand for high speed and high precision vision positioning system. To locate a rectangular lead component with high accuracy and reliability, a new visual positioning method was introduced. Considering the limitations of Ghosal sub-pixel edge detection algorithm, an improved algorithm was proposed, in which Harris corner features were used to coarsely detect the edge points and Zernike moments were adopted to accurately detect the edge points. Besides, two formulas were developed to determine the edge intersections whose sub-pixel coordinates were calculated with bilinear interpolation and conjugate gradient method. The last experimental results show that the proposed method can detect the deflection and offset, and the detection errors are less than 0.04° and 0.02 pixels.
基金supported by a grant from Research year of Inje University in 2008(0001200811700)
文摘This work proposes a map-based control method to improve a vehicle's lateral stability, and the performance of the proposed method is compared with that of the conventional model-referenced control method. Model-referenced control uses the sliding mode method to determine the compensated yaw moment; in contrast, the proposed map-based control uses the compensated yaw moment map acquired by vehicle stability analysis. The vehicle stability region is calculated by a topological method based on the trajectory reversal method. A 2-DOF vehicle model and Pacejka's tire model are used to evaluate the proposed map-based control method. The properties of model-referenced control and map-based control are compared under various road conditions and driving inputs. Model-referenced control uses a control input to satisfy the linear reference model, and it generates unnecessary tire lateral forces that may lead to worse performance than an uncontrolled vehicle with step steering input on a road with a low friction coefficient. However, map-based control determines a compensated yaw moment to maintain the vehicle within the stability region,so the typical responses of vehicle enable to converge rapidly. The simulation results with sine and step steering show that map-based control provides better the tracking responsibility and control performance than model-referenced control.
文摘VFT (variable frequency transformer) has been recently used as art alternative to HVDC (high voltage direct current) to control power flow between asynchronous networks. VFT consumes less reactive power than a back-to-back HVDC system, provides faster initial transient recovery, and has better natural damping capability. VFT is simply a DFIM (doubly-fed induction machine) where the machine torque controls the power flow from stator to rotor and vice versa. The main disadvantage of this VFT is the slip rings and brushes required for the rotor circuit, especially in bulk power transmission. The BDFM (brushless doubly-fed machine) with nested cage rotor machine is proved to be a comparable alternative to conventional DFIM in many applications with the advantage that all windings being in the stator frame with fixed output terminals. In this paper, the BDFM is used as a BVFT (brushless variable frequency transformer). A prototype machine is designed and simulated to verify the system validity.
基金Supported by The National Natural Science Foundation of China,No. 30870364Fund for Key Laboratory of Digestive System Tumors,Gansu Province,No. lzujbky-2011-t03
文摘AIM:To clarify the role of activated Notch2 in the invasiveness of gastric cancer.METHODS:To investigate the invasiveness of silencing Notch2 gene expression,we established a Notch2small interfering RNA(siRNA) transfected cell line using the MKN-45 gastric cancer cell line.After the successful transfection confirmed by real-time reverse transcription-polymerase chain reaction(RT-PCR) and Western blotting,migration and invasion assays were employed to evaluate the aggressiveness of the gastric cancer.RT-PCR and Western blottings were employed to confirm the down-regulation of Notch2 and to evaluate the expression of epithelial mesenchymal transition-related gene matrix metallopeptidase 9(MMP9),Akt,p-Akt.To confirm the relationship between PI3KAkt and MMP9,the PI3K inhibitor LY294002 was used to treat MKN-45 cells.RESULTS:Notch2 expression was dramatically decreased after Notch2 siRNA transfection(100.00% ± 9.74% vs 11.61% ± 3.85%,P 〈 0.01 by qRT-PCR).There was also a marked reduction of Notch target gene Hes1(100.00% ± 4.74% vs 61.61% ± 3.58%,P 〈 0.05) at the mRNA,indicating an inhibition of Notch signaling.Inhibition of Notch signaling was also confirmed by the marked reduction of Notch2 intracellular domain at the protein levels(100.00% ± 9.74% vs 65.61% ± 7.58%,P 〈 0.05).Down-regulation of Notch2 by siRNA enhanced tumor cell invasion(100.00% ± 21.64% vs 162.22% ± 16.84%,P 〈 0.05) and expression of MMP9(1.56 fold,P 〈 0.05),and activated the pro-MMP9 protein to its active form(1.48 fold,P 〈 0.05).There was no significant difference in the protein levels of Akt between the two groups(100.00% ± 10.87% vs 96.61% ± 7.33%,P 〉 0.05),while down-regulation of Notch2 elevated p-Akt expression(100.00% ± 9.87% vs 154.61% ± 13.10%,P 〈 0.05).Furthermore,p-Akt and MMP9 was down-regulated in response to the inhibitor LY294002(p-Akt 100.00% ± 8.87% vs 58.27% ± 5.01%,P 〈 0.05;MMP9 100.00% ± 9.17% vs 50.03% ± 4.88%,P 〈 0.05).CONCLUSION:Notch2 may negatively regulate cell invasion by inhibiting the PI3K-Akt signaling pathway