Liver fibrosis is an important pathological precondition for hepatocellular carcinoma.The degree of hepatic fibrosis is positively correlated with liver cancer.Liver fibrosis is a series of pathological and physiologi...Liver fibrosis is an important pathological precondition for hepatocellular carcinoma.The degree of hepatic fibrosis is positively correlated with liver cancer.Liver fibrosis is a series of pathological and physiological process related to liver cell necrosis and degeneration after chronic liver injury,which finally leads to extracellular matrix and collagen deposition.The early detection and precise staging of fibrosis and cirrhosis are very important for early diagnosis and timely initiation of appropriate therapeutic regimens.The risk of severe liver fibrosis finally progressing to liver carcinoma is＆gt;50%.It is known that biopsy is the gold standard for the diagnosis and staging of liver fibrosis.However,this method has some limitations,such as the potential for pain,sampling variability,and low patient acceptance.Furthermore,the necessity of obtaining a tissue diagnosis of liver fibrosis still remains controversial.An increasing number of reliable non-invasive approaches are now available that are widely applied in clinical practice,mostly in cases of viral hepatitis,resulting in a significantly decreased need for liver biopsy.In fact,the noninvasive detection and evaluation of liver cirrhosis now has good accuracy due to current serum markers,ultrasound imaging,and magnetic resonance imaging quantification techniques.A prominent advantage of the non-invasive detection and assessment of liver fibrosis is that liver fibrosis can be monitored repeatedly and easily in the same patient.Serum biomarkers have the advantages of high applicability（〉95%）and good reproducibility.However,their results can be influenced by different patient conditions because none of these markers are liver-specific.The most promising techniques appear to be transient elastography and magnetic resonance elastography because they provide reliable results for the detection of fibrosis in the advanced stages,and future developments promise to increase the reliability and accuracy of the staging of hepatic fibrosis.This article aims to describe the recent progress in the development of non-invasive assessment methods for the staging of liver fibrosis,with a special emphasize on computer-aided quantitative and deep learning methods.展开更多
Let ARDkCS（v） denote an almost resolvable directed k-cycle system of order v. It is clear that a necessary condition for the existence of an ARDkCS（v） is v=1（mod k）. For k：3,4,5 and 6, the existence of an ARDk...Let ARDkCS（v） denote an almost resolvable directed k-cycle system of order v. It is clear that a necessary condition for the existence of an ARDkCS（v） is v=1（mod k）. For k：3,4,5 and 6, the existence of an ARDkCS （v） had been completely solved. This paper shows that there exists an ARD7CS（v） if and only if v≡1 （rood 7） and v≥8.展开更多
In this paper,by applying Lasalle's in variance principle and some results about the trace of a matrix,we propose a method for estimating the topological structure of a discrete dynamical network based on the dyna...In this paper,by applying Lasalle's in variance principle and some results about the trace of a matrix,we propose a method for estimating the topological structure of a discrete dynamical network based on the dynamicalevolution of the network.The network concerned can be directed or undirected,weighted or unweighted,and the localdynamics of each node can be nonidentical.The connections among the nodes can be all unknown or partially known.Finally,two examples,including a Henon map and a central network,are illustrated to verify the theoretical results.展开更多
The stabilization with receding horizon control （RHC） of It5 stochastic time-varying systems is studied in this paper. Based on monotonically non-increasing of optimal cost and stochastic Lyapunov stability theory, ...The stabilization with receding horizon control （RHC） of It5 stochastic time-varying systems is studied in this paper. Based on monotonically non-increasing of optimal cost and stochastic Lyapunov stability theory, a necessary and sufficient stabilization condition on the terminal weighting matrix is proposed, which guarantees the mean-square stability of the closed-loop system. The explicit receding horizon controller is obtained by employing stochastic maximum principle. Simulations demonstrate the effectiveness of the proposed method.展开更多
Discerning electromagnetically induced transparency(EIT) from Autler–Townes splitting(ATS) is a significant issue in quantum optics and has attracted wide attention in various three-level configurations. Here we pres...Discerning electromagnetically induced transparency(EIT) from Autler–Townes splitting(ATS) is a significant issue in quantum optics and has attracted wide attention in various three-level configurations. Here we present a detailed study of EIT and ATS in a five-level atomic system considered to be composed of a four-level Y-type subsystem and a three-level Λ-type subsystem. In our theoretical calculations with standard density matrix formalism and steadystate approximation, we obtain the general analytical expression of the first-order matrix element responsible for the probe-field absorption. In light of the well-known three-level EIT and ATS criteria, we numerically show an intersection of EIT with ATS for the Y-type subsystem. Furthermore, we show that an EIT dip is sandwiched between two ATS dips(i.e., multi-dip mixture of EIT and ATS) in the absorption line for the five-level system, which can be explained by the dressed-state theory and Fano interference.展开更多
文摘Liver fibrosis is an important pathological precondition for hepatocellular carcinoma.The degree of hepatic fibrosis is positively correlated with liver cancer.Liver fibrosis is a series of pathological and physiological process related to liver cell necrosis and degeneration after chronic liver injury,which finally leads to extracellular matrix and collagen deposition.The early detection and precise staging of fibrosis and cirrhosis are very important for early diagnosis and timely initiation of appropriate therapeutic regimens.The risk of severe liver fibrosis finally progressing to liver carcinoma is＆gt;50%.It is known that biopsy is the gold standard for the diagnosis and staging of liver fibrosis.However,this method has some limitations,such as the potential for pain,sampling variability,and low patient acceptance.Furthermore,the necessity of obtaining a tissue diagnosis of liver fibrosis still remains controversial.An increasing number of reliable non-invasive approaches are now available that are widely applied in clinical practice,mostly in cases of viral hepatitis,resulting in a significantly decreased need for liver biopsy.In fact,the noninvasive detection and evaluation of liver cirrhosis now has good accuracy due to current serum markers,ultrasound imaging,and magnetic resonance imaging quantification techniques.A prominent advantage of the non-invasive detection and assessment of liver fibrosis is that liver fibrosis can be monitored repeatedly and easily in the same patient.Serum biomarkers have the advantages of high applicability（〉95%）and good reproducibility.However,their results can be influenced by different patient conditions because none of these markers are liver-specific.The most promising techniques appear to be transient elastography and magnetic resonance elastography because they provide reliable results for the detection of fibrosis in the advanced stages,and future developments promise to increase the reliability and accuracy of the staging of hepatic fibrosis.This article aims to describe the recent progress in the development of non-invasive assessment methods for the staging of liver fibrosis,with a special emphasize on computer-aided quantitative and deep learning methods.
基金Natural Science Research Leading Item ofJiangsu (No.04 DJ110144) Natural Out-standing Younger Science Foundation(No.60225007)and Postdoctoral ScienceFoundation of China(No.20020248024)
文摘Let ARDkCS（v） denote an almost resolvable directed k-cycle system of order v. It is clear that a necessary condition for the existence of an ARDkCS（v） is v=1（mod k）. For k：3,4,5 and 6, the existence of an ARDkCS （v） had been completely solved. This paper shows that there exists an ARD7CS（v） if and only if v≡1 （rood 7） and v≥8.
基金Supported by the Foundation of Jiangsu Polytechnic University under Grant No.JS200805National Natural Science Foundation of China under Grant No.10672146Shanghai Leading Academic Discipline Project under Grant No.S30104
文摘In this paper,by applying Lasalle's in variance principle and some results about the trace of a matrix,we propose a method for estimating the topological structure of a discrete dynamical network based on the dynamicalevolution of the network.The network concerned can be directed or undirected,weighted or unweighted,and the localdynamics of each node can be nonidentical.The connections among the nodes can be all unknown or partially known.Finally,two examples,including a Henon map and a central network,are illustrated to verify the theoretical results.
基金supported by the Taishan Scholar Construction Engineering by Shandong Governmentthe National Natural Science Foundation of China under Grant Nos.61120106011 and 61573221
文摘The stabilization with receding horizon control （RHC） of It5 stochastic time-varying systems is studied in this paper. Based on monotonically non-increasing of optimal cost and stochastic Lyapunov stability theory, a necessary and sufficient stabilization condition on the terminal weighting matrix is proposed, which guarantees the mean-square stability of the closed-loop system. The explicit receding horizon controller is obtained by employing stochastic maximum principle. Simulations demonstrate the effectiveness of the proposed method.
基金Supported by the National Natural Science Foundation of China under Grant Nos.11274132,11547208the Science Foundation of China Three Gorges University
文摘Discerning electromagnetically induced transparency(EIT) from Autler–Townes splitting(ATS) is a significant issue in quantum optics and has attracted wide attention in various three-level configurations. Here we present a detailed study of EIT and ATS in a five-level atomic system considered to be composed of a four-level Y-type subsystem and a three-level Λ-type subsystem. In our theoretical calculations with standard density matrix formalism and steadystate approximation, we obtain the general analytical expression of the first-order matrix element responsible for the probe-field absorption. In light of the well-known three-level EIT and ATS criteria, we numerically show an intersection of EIT with ATS for the Y-type subsystem. Furthermore, we show that an EIT dip is sandwiched between two ATS dips(i.e., multi-dip mixture of EIT and ATS) in the absorption line for the five-level system, which can be explained by the dressed-state theory and Fano interference.
