短暂性全面性遗忘症（Transient global amnesia syndrome．TGA）临床较为少见，其特点为突然发生的短暂性近事遗忘的临床综合征，发作持续时间1～24小时不等。发作时患者不能记忆新事物，伴有不同程度的远近记忆丧失，但自知力、书写...短暂性全面性遗忘症（Transient global amnesia syndrome．TGA）临床较为少见，其特点为突然发生的短暂性近事遗忘的临床综合征，发作持续时间1～24小时不等。发作时患者不能记忆新事物，伴有不同程度的远近记忆丧失，但自知力、书写、谈话、计算能力保持良好。现将我科2例此类病人报告如下：展开更多
OBJECTIVE: To study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA). METHODS: Three patients with TGA were given mini-mental state examination (MMSE), revised Wechsler...OBJECTIVE: To study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA). METHODS: Three patients with TGA were given mini-mental state examination (MMSE), revised Wechsler memory scale (WMS-R) examination and magnetic resonance imaging (MRI) scans after they had been diagnosed as TGA. Using (18)F labelled deoxyglucose as tracer, patients were given a positron emission tomography (PET) examination at different periods during recovery. RESULTS: No obvious abnormality was found in MMSE and MRI scans in the three patients. However, WMS-R examination and cerebral PET imaging displayed cognitive dysfunction of varying degrees and low metabolism in local areas related to memory in 2 of 3 patients. CONCLUSIONS: In TGA patients, cognitive function and cerebral metabolic levels are closely correlated with duration of symptoms. It is necessary to stop the TGA attack as quickly as possible early time.展开更多
文摘短暂性全面性遗忘症（Transient global amnesia syndrome．TGA）临床较为少见，其特点为突然发生的短暂性近事遗忘的临床综合征，发作持续时间1～24小时不等。发作时患者不能记忆新事物，伴有不同程度的远近记忆丧失，但自知力、书写、谈话、计算能力保持良好。现将我科2例此类病人报告如下：
文摘OBJECTIVE: To study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA). METHODS: Three patients with TGA were given mini-mental state examination (MMSE), revised Wechsler memory scale (WMS-R) examination and magnetic resonance imaging (MRI) scans after they had been diagnosed as TGA. Using (18)F labelled deoxyglucose as tracer, patients were given a positron emission tomography (PET) examination at different periods during recovery. RESULTS: No obvious abnormality was found in MMSE and MRI scans in the three patients. However, WMS-R examination and cerebral PET imaging displayed cognitive dysfunction of varying degrees and low metabolism in local areas related to memory in 2 of 3 patients. CONCLUSIONS: In TGA patients, cognitive function and cerebral metabolic levels are closely correlated with duration of symptoms. It is necessary to stop the TGA attack as quickly as possible early time.
