针对性护理干预在胃癌化疗患者中的应用效果及其对患者短期生活质量的影响评价

目的探讨针对性护理干预在胃癌化疗患者中的应用效果及其对患者短期生活质量的影响评价。方法选取2010年4月~2011年12月间我院诊治的胃癌化疗患者,共计88例。随机分成两组,分别为试验组和对照组。试验组采用针对性护理,对照组采用常规护理。比较两组的应用效果。对比试验组与对照组应用效果和短期生活质量。结果试验组与对照组相比较,试验组的应用效果明显比对照组好,两者有显著差异,差异有统计学意义。在短期生活质量方面,对照组在短期生活质量明显低于试验组,两组有显著差异,差异具有统计学意义。结论针对性护理在治疗胃癌化疗患者中有很显著的疗效,能改善胃癌患者的营养不良状况,提高患者的生活质量与生存率,有一定的临床意义。

预防性造口对腹腔镜直肠癌低位前切除术后短期生活质量的影响分析

比较分析预防性造口对于腹腔镜直肠癌低位前切除术后患者短期生活质量产生的主要影响,借此优化诊疗服务效果,并为患者生活质量、康复质量的提高起到一定的促进作用。方法:从 2019 年 10 月 -2020 年 10 月间在我院接受腹腔镜低位前切除术的直肠癌患者中随机抽选 100 例,利用数字分组法分成对照组 50 例和观察组 50 例。对照组实行常规化的诊疗操作,观察组则实行预防性回肠造口。观察比较两组患者康复质量、短期生活质量的综合评分指标,通过发放调查问卷,统计分析两组患者的诊疗服务满意度、术后并发症发生率。结果:观察组腹腔镜直肠癌低位前切除术患者的短期生活质量明显提高,术后康复质量的综合评分指标均优于对照组;观察组腹腔镜直肠癌低位前切除术患者的诊疗服务满意度高达(96.26%),对照组腹腔镜直肠癌低位前切除术患者的诊疗服务满意度仅为(69.89%);观察组腹腔镜直肠癌低位前切除术后患者并发症的发生率普遍低于对照组。结论:预防性造口是促进腹腔镜直肠癌低位前切除术患者康复质量及短期生活质量不断提高的关键所在,能够降低患者术后并发症的发生率,提升患者的诊疗服务满意度,避免不良症状加重,直接威胁患者的生命安全。

Short and long-term efficacy of combining Fuzhengliqi mixture with acupuncture in treatment of functional constipation

OBJECTIVE: To explore the short and long-term efficacy of combining Fuzhengliqi mixture (FLM) with acupuncture in treating functional constipation (FC). METHODS: The 560 patients with confirmed diagnosis of FC were randomly assigned to four groups: FLM group, acupuncture group, combined therapy group, and control group. There were 140 cases in each group. The FLM group was administered FLM 60 mL twice a day, while the acupuncture group was treated with acupuncture at acupoints Tianshu (ST 25), Shangjuxu (ST 37), Zusanli (ST 36), Dachangshu (BL 25), and Zhigou (TE 6) twice a day, the combined therapy group with FLM and acupuncture, and the control group was administered mosapride (5 mg thrice a day) and Macrogol 4000 (10 g twice a day). The treatment lasted 6 weeks. The defecation interval, stool property, constipation symptoms, and accompanying symptomswere recorded, graded, and scored.The gastrointestinal transit time (GITT) and motilin (MTL) level in serum and life quality score were detected at three time points (pre-treatment, at the end of treatment, and 60 weeks post-treatment). Moreover, the adverse reactions were also observed. RESULTS: In the FLM group 2 cases were eliminated for not taking medication strictly according to the research plan and 1 case was lost to follow-up, while 2 cases in the acupuncture group and 2 cases in the combined therapy group were lost to follow-up. Compared with those detected pre-treat- ment, the defecation interval, stool property, consti- pation symptom grade, accompanying symptom grade, and GITT were all decreased markedly at the end of treatment in every group, while the MTL levels in serum and life quality score were increased markedly (P<0.01), the above-mentioned detecting indices were better in the combined therapy group than those in other groups (P<0.05). Compared with the end of treatment, above-mentioned detecting indices all recurred significantly in the FLM group and control group 60 weeks post-treatment (P>0.05), but these indices recurred insignificantly in the acupuncture and combined therapy groups (P>0.05). The short and long-term total effective rates in the combined therapy group were significantly different from those in other groups (P<0.05 or P<0.01). No serious adverse reactions were found in four groups. CONCLUSION: Both FLM and acupuncture can significantly shorten the defecation interval and GITT, increase MTL levels in serum, decrease the scores of stool property, constipation symptoms, and accompanying symptoms in patients with FC to increase their life quality. The combined therapy is much better in long-term efficacy and the safety is also good, worth spreading in clinical practice.