短期饮食控制对妊娠期糖尿病患者血糖波动的疗效观察

目的:分析短期饮食控制对妊娠期糖尿病患者血糖波动和生活质量的影响。方法:2018年8月-2019年8月收治妊娠期糖尿病患者92例,根据护理措施不同分为两组,各46例。参照组接受常规护理;试验组接受短期饮食控制护理。比较两组患者血糖指标水平及生活质量评分。结果:试验组护理后空腹血糖(FBG)、餐后2 h血糖(2hPBG)及糖化血红蛋白(HbA1c)水平均低于参照组,差异有统计学意义(P<0.05);试验组生活质量各项评分均高于参照组,差异有统计学意义(P<0.05)。结论:妊娠期糖尿病患者采用短期饮食控制护理,可有效降低血糖指标水平,提高患者生活质量。

2型糖尿病住院患者短期饮食、运动跟踪指导临床观察

目的:通过对2型糖尿病住院患者短期饮食、运动跟踪指导,观察其日后自我管理血糖的能力。方法将我院内分泌科住院的2型糖尿病患者60例,均无严重并发症,肝肾功能正常,随机分为实验组30例和对照组30例,数据采用SPSS19.0软件进行统计学分析。结果接受短期饮食、运动跟踪指导的患者2月后FPG、2hPPG、HbA1c较未接受指导者显著降低(P<0.01)。结论短期饮食、运动跟踪指导能提高住院糖尿病患者日后自我管理能力。

短期限制饮食对糖尿病患者脂肪分泌激素与胃肠激素的影响

目的 探讨短期限制饮食对糖尿病患者脂肪分泌激素与胃肠激素的影响.方法 选取2015年2月至2016年1月糖尿病患者72例,对其进行短期限制饮食,比较限制饮食前后患者一般代谢指标、糖代谢指标及脂肪分泌激素、胃肠激素变化.结果 限制饮食后,糖尿病患者的体质量、体质量指数、腰围、脂肪含量及脂肪百分比低于限制饮食前,差异有统计学意义（P＜0.05）.限制饮食后,糖尿病患者空腹血糖、空腹胰岛素、糖化血红蛋白及HOMA-IR水平低于限制饮食前,差异有统计学意义（P＜0.05）.限制饮食后,糖尿病患者的瘦素[（7.4±2.4）μg/L]、抵抗素[（14.8±5.3）μg/L]、胰岛淀粉样多肽[（19.2±8.2）pg/ml]低于限制饮食前,胃促生长素[（20.6±6.7）pg/ml]高于限制饮食前,差异有统计学意义（P＜0.05）.结论 短期限制饮食能够明显改善糖尿病患者的糖代谢,降低脂肪含量,促进胃促生长素分泌.

Effects of the Modified Linggui Zhugan Decoction(加味苓桂术甘汤) Combined with Short-term Very Low Calorie Diets on Glycemic Control in Newly Diagnosed Type 2 Diabetics

Objective:To evaluate the effects of the modified Linggui Zhugan Decoction(加味苓桂术甘汤) combined with short-term very low calorie diets(VLCDs) on glycemic control in newly diagnosed type 2 diabetes mellitus(T2DM) patients.Methods:A total of 20 subjects with newly diagnosed T2DM were treated with the modified Linggui Zhugan Decoction(one-month administration) combined with short-term VLCDs(5 days),and 3-months follow-up.A standard 75-g oral-glucose-tolerance test(OGTT) indexes fasting plasma glucose(FPG),post-prandial 0.5 h and 2 h plasma glucose(P0.5hPG,P2hPG),glycated hemoglobin A1C(GHbA1C),body weight,body mass index(BMI),insulin function,insulin resistance index,incidence of hypoglycemia,and the liver and renal functions were evaluated before and after treatment.Correlations of BMI with insulin function and insulin resistance were also assessed.Results:After the treatment,the patients' plasma glucose decreased steadily,FPG decreased from 5.8±0.9 mmol/L at pre-treatment to 5.0±0.6 mmol/L at 3-months follow-up(P<0.05),and P2hPG decreased from 11.7±3.8 mmol/L at pre-treatment to 6.9±0.9 mmol/L at 3-months follow-up(P<0.01).The level of GHbA1C declined from(6.47±1.24)% at pre-treatment to(6.14±0.99)% at 3-months follow-up(P<0.01).Body weight and BMI also declined significantly.Insulin resistance index was improved obviously and no event of hypoglycemia occurred.Part of the patients companied with fatty liver had a transient increase in hepatic transaminase during the treatment,but it turned to normal after the treatment.Conclusions:The modified Linggui Zhugan Decoction combined with short-term VLCDs can be safely implemented for steady glycemic control in newly diagnosed T2DM patients.

Protective effects of Modified Linggui Zhugan Decoction combined with short-term very low calorie diets on cardiovascular risk factors in obese patients with impaired glucose tolerance

OBJECTIVE:To observe the protective effects of modified Linggui Zhugan Decoction combined with short-term very low calorie diets(VLCDs) on cardiovascular risk factors in obese patients with impaired glucose tolerance(IGT).METHODS:Eighty-five obese patients with IGT of spleen hypofunction and dampness accumulation type were randomly divided into treated group(n=45)and control group(n=40).The treated group was given Linggui Zhugan Decoction combined short-term VLCDs.The control group was given basic weight-reduction treatment.The total course was 6 months.Changes of fasting plasma glucose(FPG),2-hour postprandial blood glucose(2hPG),glycosylated hemoglobin(HbA1c),fasting insulin(FINS),lipid metabolism,blood pressure,body mass index(BMI) and waist circumference(WC) were observed,and the outcomes were reviewed after the treatment.RESULTS:Compared with the control group,the levels of FPG,2hPG,HbA1c,FINS,HOMA-IR decreased significantly(P<0.05),and the indexes of total cholesterol(TC),triglyceride(TG),low-density lipoprotein(LDL),systolic blood pressure(SBP),diastolic blood pressure(DBP),BMI and WC were improved significantly(P<0.05) in the treated group.The transformation rate of normal glucose tolerance(NGT) was higher in treatment group than control group(P<0.01).No severe adverse reaction was found in the therapeutic course.CONCLUSION:The modified Linggui Zhugan Decoction combined with short-term VLCDs has good protective effects on cardiovascular risk factors as a treatment intervention for IGT with obesity,as it could improve glycometabolism,significantly decrease the levels of blood pressure,blood lipids,BMI,WC and effectively cut-off and reverse the development of diabetes mellitus.