The research reviewed biological characters and nutritional value of Chenopodium quinoa and concluded status quo of domestic cultivation and problems at promotion, as wel as application prospect in order to provide re...The research reviewed biological characters and nutritional value of Chenopodium quinoa and concluded status quo of domestic cultivation and problems at promotion, as wel as application prospect in order to provide references for re-search and development of Chenopodium quinoa.展开更多
In traditional folk music research, when many questions can not be answered from the literature.Please go to the fields and go to the places where these folk music used to be or is being spread. In the fields, we can ...In traditional folk music research, when many questions can not be answered from the literature.Please go to the fields and go to the places where these folk music used to be or is being spread. In the fields, we can objectively record the traces of the artists 'activities with words, images, or videos. After careful analysis and consideration of the folk tunes while they performed in musician's mouth and hands, we will get unexpected results."Hai Zhou Five Main Tunes (HZFMT)"is a typical case. If you only look at the literature, it is only a local folk narrative tunes. It is not uncommon throughout the country. However, if we go deep into the field investigation, after comparison and analysis, we can see that some of the singles music is the art of Sanqu singing that did not disappear from the Ming and Qing dynasties. These tunes are not lost, but they are handed down from generation to generation in the art population. It is also an art treasure created by the salt merchant culture展开更多
The Federal Commission for Protection against Health Risks in Mexico (COFEPRIS) is responsible for the regulation and health promotion of the production, commercialization, import, export, publicity or involuntary e...The Federal Commission for Protection against Health Risks in Mexico (COFEPRIS) is responsible for the regulation and health promotion of the production, commercialization, import, export, publicity or involuntary exposure of medicines and technologies for health. For its part, the Mexican Institute of Industrial Property (IMPI) is a decentralized public body with legal personality, own property and legal authority to administer the industrial property system in our country. In the year 2000, on September 19, the official journal published the linking of patents related to allopathic medicines and the sanitary registry. Objectives: To publicize the process of linking the Sanitary-Patent Registry as a case study to delimit the scope of the new pharmaceutical products. Methodology: Request the information to COFEPRIS for the registration of a new pharmaceutical product; Establish flow diagrams for the registration of: innovative products, generic products, biotech products and bio similar products; Integrate the documents in the dossier of the pharmaceutical product for sanitary registration; Elaborate sworn letter of non-invasion of patents and study of patents; Submit the Health Registry; Intergovernmental consultation. Sanitary Registry Results: Search of patents in databases to elaborate state of the art, to write letter under protest to say truth that is not invading any patent, when developing a composition of cetuximab, as generic product since the patent molecule expired in 2016 and 11 patents related to compositions, preparations and finished product preparation processes. Conclusions: COFEPRIS will determine through intergovernmental consultation with the IMPI whether or not a patent is invaded, according to the case it will grant the registration or send the corresponding prevention for cetuximab, in case that invading can also be a refusal of grant.展开更多
Through the in vitro cell-based assay, a series of experiments to investigate the efficacy of "space ginseng yeast", which were obtained from space breeding technology and modern fermentation engineering wer...Through the in vitro cell-based assay, a series of experiments to investigate the efficacy of "space ginseng yeast", which were obtained from space breeding technology and modern fermentation engineering were conducted in order to provide theoretical basis and scientific guide for the potential applications in cosmetic areas from various aspects. The results have shown that this active ingredient can improve the proliferation, colony forming efficiency and Scratch repair ability of human primary keratinocytes. Moreover, it can significantly increase the expression of Perlecan which is key protein in the basal layer of the skin. Meanwhile, "space ginseng yeast" can help the cell morphology recovery and improve Perlecan, collagen I and elastin expression on the fibroblasts after heavy ion irradiation. All of these results showed that the "space ginseng yeast" displays potential applications on skin regeneration in cosmetic industry.展开更多
With the continuous development of human society, the damage to the natural environment is becoming increasingly large, causing crisis events to occur frequently. In recent years, the study of community resilience is ...With the continuous development of human society, the damage to the natural environment is becoming increasingly large, causing crisis events to occur frequently. In recent years, the study of community resilience is becoming popular among scholars because of its perspective on disaster prevention and mitigation. In this study, we apply database retrieval to untangle community resilience-related papers from multiple directions. We analyze the connotation, attribute, and composition of community, resilience, and community resilience comprehensively by summarizing important issues and research progress in community resilience. Challenges and shortcomings faced by community resilience development are also determined. Moreover, we put forward the research directions that future research can focus on. Through literature review, current research on community resilience focuses on the following aspects: "infrastructure construction," "crowd in the community," "economic resilience,""social capital," and "measurement of community resilience." Such research is not yet systematic and relatively decentralized. The attention to collective resilience in the community is relatively weak, which makes achieving the goal of "people-oriented and systematic control" difficult.Therefore, this study states that the development of future community resilience should stand from the perspective of"system of system" and build on knowledge and tools of various relevant domains. Therefore, public needs and participation are highlighted as breakthrough points. The research should integrate infrastructure and economic resilience, social resource allocation, network connection,and other aspects to build a holistic and functional resilient community.展开更多
Let F be a pure quintic field. In this paper, we present some results for the p-rank of K2OF, where p is an odd prime number. In particular, the 5-rank of K20F is studied by the reflection theorem. Some explicit resul...Let F be a pure quintic field. In this paper, we present some results for the p-rank of K2OF, where p is an odd prime number. In particular, the 5-rank of K20F is studied by the reflection theorem. Some explicit results on the 5-rank of K20F are given in some special cases.展开更多
基金Supported by Coarse Cereal Innovation Team of Shandong Province Modern Agricultural Technology SystemYouth Foundation of Shandong Academy of Agricultural Sciences(2014QNM09)~~
文摘The research reviewed biological characters and nutritional value of Chenopodium quinoa and concluded status quo of domestic cultivation and problems at promotion, as wel as application prospect in order to provide references for re-search and development of Chenopodium quinoa.
文摘In traditional folk music research, when many questions can not be answered from the literature.Please go to the fields and go to the places where these folk music used to be or is being spread. In the fields, we can objectively record the traces of the artists 'activities with words, images, or videos. After careful analysis and consideration of the folk tunes while they performed in musician's mouth and hands, we will get unexpected results."Hai Zhou Five Main Tunes (HZFMT)"is a typical case. If you only look at the literature, it is only a local folk narrative tunes. It is not uncommon throughout the country. However, if we go deep into the field investigation, after comparison and analysis, we can see that some of the singles music is the art of Sanqu singing that did not disappear from the Ming and Qing dynasties. These tunes are not lost, but they are handed down from generation to generation in the art population. It is also an art treasure created by the salt merchant culture
文摘The Federal Commission for Protection against Health Risks in Mexico (COFEPRIS) is responsible for the regulation and health promotion of the production, commercialization, import, export, publicity or involuntary exposure of medicines and technologies for health. For its part, the Mexican Institute of Industrial Property (IMPI) is a decentralized public body with legal personality, own property and legal authority to administer the industrial property system in our country. In the year 2000, on September 19, the official journal published the linking of patents related to allopathic medicines and the sanitary registry. Objectives: To publicize the process of linking the Sanitary-Patent Registry as a case study to delimit the scope of the new pharmaceutical products. Methodology: Request the information to COFEPRIS for the registration of a new pharmaceutical product; Establish flow diagrams for the registration of: innovative products, generic products, biotech products and bio similar products; Integrate the documents in the dossier of the pharmaceutical product for sanitary registration; Elaborate sworn letter of non-invasion of patents and study of patents; Submit the Health Registry; Intergovernmental consultation. Sanitary Registry Results: Search of patents in databases to elaborate state of the art, to write letter under protest to say truth that is not invading any patent, when developing a composition of cetuximab, as generic product since the patent molecule expired in 2016 and 11 patents related to compositions, preparations and finished product preparation processes. Conclusions: COFEPRIS will determine through intergovernmental consultation with the IMPI whether or not a patent is invaded, according to the case it will grant the registration or send the corresponding prevention for cetuximab, in case that invading can also be a refusal of grant.
文摘Through the in vitro cell-based assay, a series of experiments to investigate the efficacy of "space ginseng yeast", which were obtained from space breeding technology and modern fermentation engineering were conducted in order to provide theoretical basis and scientific guide for the potential applications in cosmetic areas from various aspects. The results have shown that this active ingredient can improve the proliferation, colony forming efficiency and Scratch repair ability of human primary keratinocytes. Moreover, it can significantly increase the expression of Perlecan which is key protein in the basal layer of the skin. Meanwhile, "space ginseng yeast" can help the cell morphology recovery and improve Perlecan, collagen I and elastin expression on the fibroblasts after heavy ion irradiation. All of these results showed that the "space ginseng yeast" displays potential applications on skin regeneration in cosmetic industry.
基金funded by the National Key R&D Program of China(Grant No.2017YFC0803308)Humanities and Social Science Foundation of the Ministry of Education of China(Grant No.13YJCZH129)+1 种基金National Natural Science Foundation of China(Grant Nos.U1709212,71741023 and 71741025)Tsinghua University Initiative Scientific Research Program(Grant Nos.2014z21050 and 2015THZ0)
文摘With the continuous development of human society, the damage to the natural environment is becoming increasingly large, causing crisis events to occur frequently. In recent years, the study of community resilience is becoming popular among scholars because of its perspective on disaster prevention and mitigation. In this study, we apply database retrieval to untangle community resilience-related papers from multiple directions. We analyze the connotation, attribute, and composition of community, resilience, and community resilience comprehensively by summarizing important issues and research progress in community resilience. Challenges and shortcomings faced by community resilience development are also determined. Moreover, we put forward the research directions that future research can focus on. Through literature review, current research on community resilience focuses on the following aspects: "infrastructure construction," "crowd in the community," "economic resilience,""social capital," and "measurement of community resilience." Such research is not yet systematic and relatively decentralized. The attention to collective resilience in the community is relatively weak, which makes achieving the goal of "people-oriented and systematic control" difficult.Therefore, this study states that the development of future community resilience should stand from the perspective of"system of system" and build on knowledge and tools of various relevant domains. Therefore, public needs and participation are highlighted as breakthrough points. The research should integrate infrastructure and economic resilience, social resource allocation, network connection,and other aspects to build a holistic and functional resilient community.
基金This paper was partially supported by National Natural Science Foundation of China under Grant 11301071 and 11471162.
文摘Let F be a pure quintic field. In this paper, we present some results for the p-rank of K2OF, where p is an odd prime number. In particular, the 5-rank of K20F is studied by the reflection theorem. Some explicit results on the 5-rank of K20F are given in some special cases.