In this work study, we investigated possibility of modifying the new Michaelis Allen, Milobendzky-Shulgin, Michaelis-Becker, Raymond reactions with organic compounds of arsenic, antimony and bismuth is discovered. A n...In this work study, we investigated possibility of modifying the new Michaelis Allen, Milobendzky-Shulgin, Michaelis-Becker, Raymond reactions with organic compounds of arsenic, antimony and bismuth is discovered. A new mechanism for possible reactions has been proposed.展开更多
It is discovered a new three-, four-component Petasis, Passerini, Hantzsch, Kabachnic-Fields, Ugi reactions with of arsine, stibine and bismuthine in organometallic chemistry. Modifications were replaced to a nitrogen...It is discovered a new three-, four-component Petasis, Passerini, Hantzsch, Kabachnic-Fields, Ugi reactions with of arsine, stibine and bismuthine in organometallic chemistry. Modifications were replaced to a nitrogen atom of classical reactions of atoms of phosphorus, arsenic, antimony and bismuth. It has been proposed a new mechanism for possible reactions.展开更多
A new approach modification reactions Atherton-Todd, Betty, Mannich and Doebner reactions with of arsine, stibine and bismuthine have been proposed in organometallic chemistry of these elements. These new reactions ca...A new approach modification reactions Atherton-Todd, Betty, Mannich and Doebner reactions with of arsine, stibine and bismuthine have been proposed in organometallic chemistry of these elements. These new reactions can be used for the synthesis of drugs and biologically active organic compound of arsenic, antimony and bismuth. A possible new mechanism of the reaction is proposed.展开更多
Trivalent organoarsenic compounds have attracted a great deal of interest because of their potential antineoplastic activities. In this work, we synthesized a series of arsenic-containing amino acid analogues by intro...Trivalent organoarsenic compounds have attracted a great deal of interest because of their potential antineoplastic activities. In this work, we synthesized a series of arsenic-containing amino acid analogues by introducing the structure of 1-arsino-2,6,7- trithiobicyclo[2.2.2]octane to the side chain of modified amino acid derivatives. The protected amino acid （6a） as a typical objective compound was applied in peptide synthesis via the classic procedures for the formation of peptide bond or removal of protecting groups. Our results showed that the application of compound 6a （or 5a） in the peptide chemistry was satisfactory.展开更多
文摘In this work study, we investigated possibility of modifying the new Michaelis Allen, Milobendzky-Shulgin, Michaelis-Becker, Raymond reactions with organic compounds of arsenic, antimony and bismuth is discovered. A new mechanism for possible reactions has been proposed.
文摘It is discovered a new three-, four-component Petasis, Passerini, Hantzsch, Kabachnic-Fields, Ugi reactions with of arsine, stibine and bismuthine in organometallic chemistry. Modifications were replaced to a nitrogen atom of classical reactions of atoms of phosphorus, arsenic, antimony and bismuth. It has been proposed a new mechanism for possible reactions.
文摘A new approach modification reactions Atherton-Todd, Betty, Mannich and Doebner reactions with of arsine, stibine and bismuthine have been proposed in organometallic chemistry of these elements. These new reactions can be used for the synthesis of drugs and biologically active organic compound of arsenic, antimony and bismuth. A possible new mechanism of the reaction is proposed.
文摘Trivalent organoarsenic compounds have attracted a great deal of interest because of their potential antineoplastic activities. In this work, we synthesized a series of arsenic-containing amino acid analogues by introducing the structure of 1-arsino-2,6,7- trithiobicyclo[2.2.2]octane to the side chain of modified amino acid derivatives. The protected amino acid （6a） as a typical objective compound was applied in peptide synthesis via the classic procedures for the formation of peptide bond or removal of protecting groups. Our results showed that the application of compound 6a （or 5a） in the peptide chemistry was satisfactory.
