椎板切除术是治疗腰椎疾病最常用的手术方法之一。而椎板切除术后硬膜周围纤维化与瘢痕组织的形成，可引起硬膜和神经根周围广泛的粘连，从而导致硬膜受压和神经根活动受限。硬膜受压和神经根活动受限是导致下腰椎术后失败综合征（faild...椎板切除术是治疗腰椎疾病最常用的手术方法之一。而椎板切除术后硬膜周围纤维化与瘢痕组织的形成，可引起硬膜和神经根周围广泛的粘连，从而导致硬膜受压和神经根活动受限。硬膜受压和神经根活动受限是导致下腰椎术后失败综合征（faild back surgery syndrome，FBSS）的主要原因之一，且此类患者再手术治疗疗效差，因此防止下腰椎手术术后粘连，提高治愈率和降低复发率，展开更多
Based on histological and immunohistochemical exami- nation of various organs of patients with autoimmune pancreatitis （AIP）, a novel clinicopathological entity of IgG4-related sclerosing disease has been proposed. ...Based on histological and immunohistochemical exami- nation of various organs of patients with autoimmune pancreatitis （AIP）, a novel clinicopathological entity of IgG4-related sclerosing disease has been proposed. This is a systemic disease that is characterized by extensive IgG4-positive plasma cells and T-lymphocyte infiltration of various organs. Clinical manifestations are apparent in the pancreas, bile duct, gallbladder, salivary gland, retroperitoneum, kidney, lung, and prosrate, in which tissue fibrosis with obliterative phlebitis is pathologically induced. AlP is not simply pancreatitis but, in fact, is a pancreatic disease indicative of IgG4- related sclerosing diseases. This disease includes AlP, sclerosing cholangitis, cholecystitis, sialadenitis, retro-peritoneal fibrosis, tubulointerstitial nephritis, interstitial pneumonia, prostatitis, inflammatory pseudotumor and lymphadenopathy, all IgG4-related. Most IgG4-related sclerosing diseases have been found to be associated with AlP, but also those without pancreatic involvement have been reported. In some cases, only one or two organs are clinically involved, while in others, three or four organs are affected. The disease occurs predominantly in older men and responds well to steroid therapy. Serum IgG4 levels and immunos-taining with anti-IgG4 antibody are useful in making the diagnosis. Since malignant tumors are frequently suspected on initial presentation, IgG4-related sclerosing disease should be considered in the differential diagnosis to avoid unnecessary surgery.展开更多
文摘椎板切除术是治疗腰椎疾病最常用的手术方法之一。而椎板切除术后硬膜周围纤维化与瘢痕组织的形成，可引起硬膜和神经根周围广泛的粘连，从而导致硬膜受压和神经根活动受限。硬膜受压和神经根活动受限是导致下腰椎术后失败综合征（faild back surgery syndrome，FBSS）的主要原因之一，且此类患者再手术治疗疗效差，因此防止下腰椎手术术后粘连，提高治愈率和降低复发率，
文摘Based on histological and immunohistochemical exami- nation of various organs of patients with autoimmune pancreatitis （AIP）, a novel clinicopathological entity of IgG4-related sclerosing disease has been proposed. This is a systemic disease that is characterized by extensive IgG4-positive plasma cells and T-lymphocyte infiltration of various organs. Clinical manifestations are apparent in the pancreas, bile duct, gallbladder, salivary gland, retroperitoneum, kidney, lung, and prosrate, in which tissue fibrosis with obliterative phlebitis is pathologically induced. AlP is not simply pancreatitis but, in fact, is a pancreatic disease indicative of IgG4- related sclerosing diseases. This disease includes AlP, sclerosing cholangitis, cholecystitis, sialadenitis, retro-peritoneal fibrosis, tubulointerstitial nephritis, interstitial pneumonia, prostatitis, inflammatory pseudotumor and lymphadenopathy, all IgG4-related. Most IgG4-related sclerosing diseases have been found to be associated with AlP, but also those without pancreatic involvement have been reported. In some cases, only one or two organs are clinically involved, while in others, three or four organs are affected. The disease occurs predominantly in older men and responds well to steroid therapy. Serum IgG4 levels and immunos-taining with anti-IgG4 antibody are useful in making the diagnosis. Since malignant tumors are frequently suspected on initial presentation, IgG4-related sclerosing disease should be considered in the differential diagnosis to avoid unnecessary surgery.
