Molecular iodine was first utilized for direct oxidation of a-isophorone （α-IP） to ketoisophorone （KIP） with molecule oxygen at room temperature and the effects of amount of iodine, solvents and reaction time wer...Molecular iodine was first utilized for direct oxidation of a-isophorone （α-IP） to ketoisophorone （KIP） with molecule oxygen at room temperature and the effects of amount of iodine, solvents and reaction time were investigated extensively. The optimized result shows that 70.2% conversion of a-isophorone and 82.6% selectivity of ketoisophorone are obtained with 15% iodine （molar fraction） in acetonitrile under photoirradiation for 5 h. Moreover, the possible mechanism is proposed.展开更多
The oxidative coupling of methylarenes and N,N-dialkylformamides was developed, and the appropriate reaction conditions were established. By using I2 as the catalyst, and tert-butyl hydroperoxide(TBHP) as the oxidant,...The oxidative coupling of methylarenes and N,N-dialkylformamides was developed, and the appropriate reaction conditions were established. By using I2 as the catalyst, and tert-butyl hydroperoxide(TBHP) as the oxidant, the reaction provided N,N-dialkylamides or N-alkylamides with moderate yields via multiple sp3 C-H bonds activation of methylarenes in aqueous and metal-free conditions.展开更多
基金Project(21071152) supported by the National Natural Science Foundation of China
文摘Molecular iodine was first utilized for direct oxidation of a-isophorone （α-IP） to ketoisophorone （KIP） with molecule oxygen at room temperature and the effects of amount of iodine, solvents and reaction time were investigated extensively. The optimized result shows that 70.2% conversion of a-isophorone and 82.6% selectivity of ketoisophorone are obtained with 15% iodine （molar fraction） in acetonitrile under photoirradiation for 5 h. Moreover, the possible mechanism is proposed.
基金This work was supported by the National Natural Science Foundation of China(21272117,20972068)the Priority Academic Program Development of Jiangsu Higher Education Institutions.
文摘The oxidative coupling of methylarenes and N,N-dialkylformamides was developed, and the appropriate reaction conditions were established. By using I2 as the catalyst, and tert-butyl hydroperoxide(TBHP) as the oxidant, the reaction provided N,N-dialkylamides or N-alkylamides with moderate yields via multiple sp3 C-H bonds activation of methylarenes in aqueous and metal-free conditions.
