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Tris对高LET碳重离子辐照下质粒DNA链断裂的保护作用
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作者 劳文艳 胡文涛 《激光生物学报》 CAS CSCD 2009年第6期751-754,共4页
利用100 keV/μm碳离子束(初始能量为290 MeV/u)照射溶解于纯水、10 mmol/L Tris、1 mmol/L EDTA及TE缓冲液中的pUC19质粒DNA。通过琼脂糖凝胶电泳技术分析了不同溶液中各种形态DNA分子所占份额,并计算得到不同剂量下平均每个质粒分子... 利用100 keV/μm碳离子束(初始能量为290 MeV/u)照射溶解于纯水、10 mmol/L Tris、1 mmol/L EDTA及TE缓冲液中的pUC19质粒DNA。通过琼脂糖凝胶电泳技术分析了不同溶液中各种形态DNA分子所占份额,并计算得到不同剂量下平均每个质粒分子中单链断裂(SSB)及双链断裂(DSB)的数目。发现Tris通过抑制SSB和DSB的产生对碳重离子辐照下的质粒DNA有明显的保护作用,而EDTA能够加剧SSB的产生而抑制DSB的形成。 展开更多
关键词 TRIS 碳重离子 辐照 质粒DNA SSB DSB
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3.0TMRI对重离子治疗Ⅱ~Ⅳ期胰腺癌的初期疗效评估
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作者 关钊钰 王建花 +1 位作者 赵致平 张雁山 《甘肃医药》 2023年第9期804-808,共5页
目的:研究Ⅱ~Ⅳ期胰腺癌患者经重离子放疗或放疗联合化疗的MRI影像学资料,以评估疗效。方法:回顾性分析我院收治的经碳离子治疗的49例Ⅱ~Ⅳ期胰腺癌患者的肿瘤轴位面积及DWI弥散加权成像中的ADC值,以治疗前数值为基线,与治疗后第1个月及... 目的:研究Ⅱ~Ⅳ期胰腺癌患者经重离子放疗或放疗联合化疗的MRI影像学资料,以评估疗效。方法:回顾性分析我院收治的经碳离子治疗的49例Ⅱ~Ⅳ期胰腺癌患者的肿瘤轴位面积及DWI弥散加权成像中的ADC值,以治疗前数值为基线,与治疗后第1个月及第3~7个月复查时的肿瘤轴位面积及ADC值进行对比。结果:在重离子放疗后第1个月复查,瘤灶面积较治疗前明显缩小,差异有统计学意义(P<0.05);分析了11例患者治疗后第3~7个月复查的轴位面积,发现瘤灶面积较治疗后第1月复查缩小(P=0.01);而重离子放疗后第1个月复查,与治疗前肿瘤ADC值相比明显升高(P<0.01)。胰腺癌经碳离子治疗前后病灶面积与ADC值的ROC曲线显示,病灶面积基线期与治疗后1个月、治疗后3~7月比较,AUC分别为0.567、0.858,提示用第3~7个月时复查瘤灶面积缩小预测重离子放疗胰腺癌有效的准确率更高。结论:重离子放疗联合化疗或单独使用治疗不能手术中晚期胰腺癌患者,初期复查疗效显著,3.0 T MRI可对重离子治疗胰腺癌患者进行疗效评估。 展开更多
关键词 胰腺癌 重离子(离子)放疗 MRI 面积 ADC
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碳离子治疗结直肠癌的基础与临床研究进展
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作者 任祥清 黄田 +2 位作者 王玉平 胡泽楠 周永宁 《中华放射肿瘤学杂志》 CSCD 北大核心 2024年第1期67-71,共5页
结直肠癌是临床常见的恶性肿瘤,放射治疗作为结直肠癌的主要治疗方法,对肿瘤进展有较好的抑制作用。近年来,碳离子因其良好的物理学及生物学优势,在对结直肠癌局部复发或者远处转移的治疗中,表现出比传统放疗更好的临床效果。本文主要... 结直肠癌是临床常见的恶性肿瘤,放射治疗作为结直肠癌的主要治疗方法,对肿瘤进展有较好的抑制作用。近年来,碳离子因其良好的物理学及生物学优势,在对结直肠癌局部复发或者远处转移的治疗中,表现出比传统放疗更好的临床效果。本文主要回顾了近年来碳离子治疗结直肠癌复发的相关基础与临床研究,以期为预防和减少结直肠癌患者放疗后不良反应及延长患者生存期提供理论依据。 展开更多
关键词 重离子放射疗法 离子 结直肠肿瘤 肿瘤复发 自噬 放疗增敏 P53基因 肠道菌群
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Hydrochemical characteristics of aquifers in Northern Gezira State,Central Sudan
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作者 Adil Elkrail 束龙仓 +1 位作者 Omer Kheir 郝振纯 《Journal of Southeast University(English Edition)》 EI CAS 2003年第3期270-274,共5页
This paper presents an assessment of the hydrochemical characteristics of groundwater in Northern Gezira State, Central Sudan. The approaches followed here include the chemical analyses for major ions chemistry and co... This paper presents an assessment of the hydrochemical characteristics of groundwater in Northern Gezira State, Central Sudan. The approaches followed here include the chemical analyses for major ions chemistry and construction of hydrochemical maps of total dissolved solids (TDS), sodium (Na +), bicarbonate (HCO 3 -), and chloride (Cl -) ions. The hydrochemical characteristics of the groundwater in each aquifer and management consideration are discussed. Sources of major ions in groundwater are analyzed. The hydrochemical maps of important species are constructed. The relationship of groundwater to use is elaborated. High concentrations of the chemical and hydrochemical constituents and the occurrence of calcretes (CaCO 3) in upper zones suggest a long history of evaporation and increasing leachates. 展开更多
关键词 total dissolved solids HARDNESS AQUIFER chemical constituents
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ORIGIN FOR IRRADIATION EFFECT OF 0.56 GeV C^(6+) ON CaVSn:YIG
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作者 熊宏齐 夏元复 侯明东 《Nuclear Science and Techniques》 SCIE CAS CSCD 1995年第1期9-13,共5页
This paper presents numerous physical characteristics of Ca, V, Sn doped yttrium iron garnet (CaVSn:YIG) irradiated with 0.56GeV carbon ions delivered by the Heavy Ion Research Facility of Lanzhou (HIRFL). The reason... This paper presents numerous physical characteristics of Ca, V, Sn doped yttrium iron garnet (CaVSn:YIG) irradiated with 0.56GeV carbon ions delivered by the Heavy Ion Research Facility of Lanzhou (HIRFL). The reason for change of the magnetic properties of the samples induced by energetic carbon ions bombardment is discussed. By comparison of this results with the irradiation effects of YIG induced by energetic argon, krypton and xenon obtained on the GANIL, Caen,France, it is concluded that the irradiation effect of 0.56 GeV C6+ on CaVSn.YIG arises from the electronic energy losses. 展开更多
关键词 Energetic carbon ion Yttrium iron garnet Irradiation effect Electronicenergy losses
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Removal of toxic metal ions using chitosan coated carbon nanotube composites for supercapacitors 被引量:2
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作者 Pin Hao Xiaoye Ma +6 位作者 Junfeng Xie Fengcai Lei Liyi Li Wenqian Zhu Xin Cheng Guanwei Cui Bo Tang 《Science China Chemistry》 SCIE EI CAS CSCD 2018年第7期797-805,共9页
Environmental pollution and energy crisis are two major global challenges to human beings.Recovering energy from wastewater is considered to be one of the effective approaches to address these two issues synchronously... Environmental pollution and energy crisis are two major global challenges to human beings.Recovering energy from wastewater is considered to be one of the effective approaches to address these two issues synchronously.As the main pollutants in wastewater,toxic heavy metal ions are the potential candidates for energy storage devices with pseudocapacitive behaviors.In this study,toxic metal ions of Cr(VI)and Cu(II)are removed efficiently by chitosan coated oxygen-containing functional carbon nanotubes,and the corresponding equilibrium adsorption capacity is 142.1 and 123.7 mg g^(-1).Followed by carbonization of metal ions-adsorbed adsorbents,Cu-and Cr N-loaded carbon composites can be obtained.Electrochemical measurements show that the supercapacitor electrodes based on Cu-and Cr N-loaded carbon composites have specific capacitance of 144.9 and 114.9 F g^(-1)at2 m V s^(-1),with superior electrochemical properties to pure chitosan coated carbon nanotubes after carbonization.This work demonstrates a new strategy for the resource-utilization of other heavy metal ions for energy devices,and also provides a new way to turn environmental pollutants into clean energy. 展开更多
关键词 heavy metal ions adsorption chitosan coated carbon nanotube supercapacitor
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