Electromagnetic signals may be a promising precursor to seismic activity which has been observed in many case studies in past decades.However,the correlation and causation between the electromagnetic signals and the s...Electromagnetic signals may be a promising precursor to seismic activity which has been observed in many case studies in past decades.However,the correlation and causation between the electromagnetic signals and the seismic activity are still unclear without intensive observation network.In order to find seismoelectromagnetic phenomenon,we deployed AETA(acoustic and electromagnetic testing all-in-one system),a high-density multi-component seismic monitoring system in the China Earthquake Science Experiment site(CESE,in Sichuan Province and Yunnan Province,China)and the capital circle(areas with a distance which is≤200 km from Beijing),to record electromagnetic and geo-acoustic data across 0.1 Hz−10 kHz.In the course of data collection,we discovered an electromagnetic waveform that occurs on a daily basis.Because the signal generally coincides with sunrise and sunset,we named this phenomenon the SRSS(Sunrise-Sunset)waveform.After conducting three statistical tests based on seismicity and SRSS,we determined that the SRSS waveform is roughly correlated with the onset of seismic activity.It generally occurs at the regions where seismicity occurs.This discovery might have significant implications with respect to the future of earthquake prediction.展开更多
AIM:To detect of colorectal cancer(CRC) circulating tumour cells(CTCs) surface antigens,we present an assay incorporating cadmium selenide quantum dots(QDs) in these paper.METHODS:The principle of the assay is the imm...AIM:To detect of colorectal cancer(CRC) circulating tumour cells(CTCs) surface antigens,we present an assay incorporating cadmium selenide quantum dots(QDs) in these paper.METHODS:The principle of the assay is the immunomagnetic separation of CTCs from body fluids in conjunction with QDs,using specific antibody biomarkers:epithelial cell adhesion molecule antibody,and monoclonal cytokeratin 19 antibody.The detection signal was acquired from the fluorescence signal of QDs.For the evaluation of the performance,the method under study was used to isolate the human colon adenocarcinoma cell line(DLD-1) and CTCs from CRC patients' peripheral blood.RESULTS:The minimum detection limit of the assay was defined to 10 DLD-1 CRC cells/mL as fluorescence was measured with a spectrofluorometer.Fluorescenceactivated cell sorting analysis and Real Time RT-PCR,they both have also been used to evaluate the performance of the described method.In conclusion,we developed a simple,sensitive,efficient and of lower cost(than the existing ones) method for the detection of CRC CTCs in human samples.We have accomplished these results by using magnetic bead isolation and subsequent QD fluorescence detection.CONCLUSION:The method described here can be easily adjusted for any other protein target of either the CTC or the host.展开更多
In order to research the danger caused by the rockburst, the electromagnetic emission （EME） in the coal rock was monitored and analyzed. The higher the stress in the coal is, the stronger the deformation and the fai...In order to research the danger caused by the rockburst, the electromagnetic emission （EME） in the coal rock was monitored and analyzed. The higher the stress in the coal is, the stronger the deformation and the failure are, and also the signal of the EME will be. The EME is increased by a relatively large margin before the slight shock and rockburst break out at spot. Therefore, some methods to monitor and forecast the danger of rockburst were proposed, including the critical point and devia- tion values, which was by non-contract method. In the end, the observation of EME in Xingfu was used to analyze and forecast the danger level by the rockburst. Then, the measures were proposed to prevent and cure the rockburst.展开更多
A versatile DNA recognition system using cadmium sulfide nanoparticles (CdS NPs) as labels was proposed for ultrasensitive detection of specific sequence DNA based on target recycling. This strategy utilized the magne...A versatile DNA recognition system using cadmium sulfide nanoparticles (CdS NPs) as labels was proposed for ultrasensitive detection of specific sequence DNA based on target recycling. This strategy utilized the magnetic particles (MNPs) for the immobilization of linker DNA and CdS NPs and the subsequent target DNA hybridization. Using the unique characteristic of nicking endonuclease for cutting one specific strand of double strand DNA (ds DNA), the linker DNA could be transected and the target DNA could be liberated for re-hybridization and hence the amount of released CdS NPs was enhanced. Due to the advantage of the MNPs and signal amplification from the target recycling, the analyte DNA could be detected by the square-wave stripping voltammetry (SWV) in a wide linear range from 0.4 fM to 100 fM with the detection limit down to 0.08 fM. The proposed DNA detection strategy possesses high sensitivity, satisfactory reproducibility and excellent stability, which might have potential in other DNA biological assays.展开更多
Superconductivity on the border of the long-range magnetic order has been discovered in Mn P under high pressures. In order to investigate the nature of the magnetic properties adjacent to the superconducting state, w...Superconductivity on the border of the long-range magnetic order has been discovered in Mn P under high pressures. In order to investigate the nature of the magnetic properties adjacent to the superconducting state, we performed zero-field 31 P NMR for Mn P single crystal under ambient and hydrostatic pressure of 2 GPa, respectively. Radio frequency power level was used to determine whether NMR signal originates from a helical state or not. When 2 GPa pressure was applied, the signal from helical state exists even above 160 K, while that from the ferromagnetic phase was not observed. Our NMR results indicate that the magnetic phase which is adjacent to the superconducting state is in a helical magnetic structure.展开更多
基金Projects(KJYY20170721151955849,JCYJ20190808161401653)supported by Fundamental Research Grant from Shenzhen Science&Technology,China。
文摘Electromagnetic signals may be a promising precursor to seismic activity which has been observed in many case studies in past decades.However,the correlation and causation between the electromagnetic signals and the seismic activity are still unclear without intensive observation network.In order to find seismoelectromagnetic phenomenon,we deployed AETA(acoustic and electromagnetic testing all-in-one system),a high-density multi-component seismic monitoring system in the China Earthquake Science Experiment site(CESE,in Sichuan Province and Yunnan Province,China)and the capital circle(areas with a distance which is≤200 km from Beijing),to record electromagnetic and geo-acoustic data across 0.1 Hz−10 kHz.In the course of data collection,we discovered an electromagnetic waveform that occurs on a daily basis.Because the signal generally coincides with sunrise and sunset,we named this phenomenon the SRSS(Sunrise-Sunset)waveform.After conducting three statistical tests based on seismicity and SRSS,we determined that the SRSS waveform is roughly correlated with the onset of seismic activity.It generally occurs at the regions where seismicity occurs.This discovery might have significant implications with respect to the future of earthquake prediction.
基金Supported by The John S Latsis Public Benefit FoundationThe Hellenic Society of Medical Oncology
文摘AIM:To detect of colorectal cancer(CRC) circulating tumour cells(CTCs) surface antigens,we present an assay incorporating cadmium selenide quantum dots(QDs) in these paper.METHODS:The principle of the assay is the immunomagnetic separation of CTCs from body fluids in conjunction with QDs,using specific antibody biomarkers:epithelial cell adhesion molecule antibody,and monoclonal cytokeratin 19 antibody.The detection signal was acquired from the fluorescence signal of QDs.For the evaluation of the performance,the method under study was used to isolate the human colon adenocarcinoma cell line(DLD-1) and CTCs from CRC patients' peripheral blood.RESULTS:The minimum detection limit of the assay was defined to 10 DLD-1 CRC cells/mL as fluorescence was measured with a spectrofluorometer.Fluorescenceactivated cell sorting analysis and Real Time RT-PCR,they both have also been used to evaluate the performance of the described method.In conclusion,we developed a simple,sensitive,efficient and of lower cost(than the existing ones) method for the detection of CRC CTCs in human samples.We have accomplished these results by using magnetic bead isolation and subsequent QD fluorescence detection.CONCLUSION:The method described here can be easily adjusted for any other protein target of either the CTC or the host.
文摘In order to research the danger caused by the rockburst, the electromagnetic emission （EME） in the coal rock was monitored and analyzed. The higher the stress in the coal is, the stronger the deformation and the failure are, and also the signal of the EME will be. The EME is increased by a relatively large margin before the slight shock and rockburst break out at spot. Therefore, some methods to monitor and forecast the danger of rockburst were proposed, including the critical point and devia- tion values, which was by non-contract method. In the end, the observation of EME in Xingfu was used to analyze and forecast the danger level by the rockburst. Then, the measures were proposed to prevent and cure the rockburst.
基金supported by the National Natural Science Foundation of China (21025522 & 20890021)the National Natural Science Foundation of China for Creative Research Groups (20821063)the National Basic Research Program of China (2007CB936404)
文摘A versatile DNA recognition system using cadmium sulfide nanoparticles (CdS NPs) as labels was proposed for ultrasensitive detection of specific sequence DNA based on target recycling. This strategy utilized the magnetic particles (MNPs) for the immobilization of linker DNA and CdS NPs and the subsequent target DNA hybridization. Using the unique characteristic of nicking endonuclease for cutting one specific strand of double strand DNA (ds DNA), the linker DNA could be transected and the target DNA could be liberated for re-hybridization and hence the amount of released CdS NPs was enhanced. Due to the advantage of the MNPs and signal amplification from the target recycling, the analyte DNA could be detected by the square-wave stripping voltammetry (SWV) in a wide linear range from 0.4 fM to 100 fM with the detection limit down to 0.08 fM. The proposed DNA detection strategy possesses high sensitivity, satisfactory reproducibility and excellent stability, which might have potential in other DNA biological assays.
基金supported by the National Basic Research Program of China(Grant No.2015CB921300)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB07020200)
文摘Superconductivity on the border of the long-range magnetic order has been discovered in Mn P under high pressures. In order to investigate the nature of the magnetic properties adjacent to the superconducting state, we performed zero-field 31 P NMR for Mn P single crystal under ambient and hydrostatic pressure of 2 GPa, respectively. Radio frequency power level was used to determine whether NMR signal originates from a helical state or not. When 2 GPa pressure was applied, the signal from helical state exists even above 160 K, while that from the ferromagnetic phase was not observed. Our NMR results indicate that the magnetic phase which is adjacent to the superconducting state is in a helical magnetic structure.
