The airborne electromagnetic (AEM) method has a high sampling rate and survey flexibility. However, traditional numerical modeling approaches must use high-resolution physical grids to guarantee modeling accuracy, e...The airborne electromagnetic (AEM) method has a high sampling rate and survey flexibility. However, traditional numerical modeling approaches must use high-resolution physical grids to guarantee modeling accuracy, especially for complex geological structures such as anisotropic earth. This can lead to huge computational costs. To solve this problem, we propose a spectral-element (SE) method for 3D AEM anisotropic modeling, which combines the advantages of spectral and finite-element methods. Thus, the SE method has accuracy as high as that of the spectral method and the ability to model complex geology inherited from the finite-element method. The SE method can improve the modeling accuracy within discrete grids and reduce the dependence of modeling results on the grids. This helps achieve high-accuracy anisotropic AEM modeling. We first introduced a rotating tensor of anisotropic conductivity to Maxwell's equations and described the electrical field via SE basis functions based on GLL interpolation polynomials. We used the Galerkin weighted residual method to establish the linear equation system for the SE method, and we took a vertical magnetic dipole as the transmission source for our AEM modeling. We then applied fourth-order SE calculations with coarse physical grids to check the accuracy of our modeling results against a 1D semi-analytical solution for an anisotropic half-space model and verified the high accuracy of the SE. Moreover, we conducted AEM modeling for different anisotropic 3D abnormal bodies using two physical grid scales and three orders of SE to obtain the convergence conditions for different anisotropic abnormal bodies. Finally, we studied the identification of anisotropy for single anisotropic abnormal bodies, anisotropic surrounding rock, and single anisotropic abnormal body embedded in an anisotropic surrounding rock. This approach will play a key role in the inversion and interpretation of AEM data collected in regions with anisotropic geology.展开更多
Objective To investigate the influence of vitamin D receptor (VDR) gene polymorphisms on susceptibility to type 1 diabetes mellitus (T1DM) in the Chinese Han population. Method One hundred and thirty-six Chinese ...Objective To investigate the influence of vitamin D receptor (VDR) gene polymorphisms on susceptibility to type 1 diabetes mellitus (T1DM) in the Chinese Han population. Method One hundred and thirty-six Chinese Han people, including 54 T1DM patients and 82 unrelated healthy subjects as control were genotyped by polymerase chain reaction-restriction fragment length polymorphism for three restriction sites in the VDR gene, which were ApaI, TaqI, and BamL Results The frequency of B allele of BsmI site in VDR gene was significantly higher in T1DM patients than in healthy subjects ( P = 0. 033 ) while no difference was found between the two groups in the distribution of ApaI and TaqI polymorphisms. Conclusion The BsmI polymorphism of VDR gene may be associated with the susceptibihty to T1DM in the Chinese Han population of Beijing.展开更多
The magnetic behavior of the mixed ferro-ferrimagnetie alloy with (Aa Bb Cc)y D structure composed of Ising spins SA=1, SB = 5/2, SC= 2, and SD = 3/2 in the presence of the external magnetic field is investigated by...The magnetic behavior of the mixed ferro-ferrimagnetie alloy with (Aa Bb Cc)y D structure composed of Ising spins SA=1, SB = 5/2, SC= 2, and SD = 3/2 in the presence of the external magnetic field is investigated by the use of the effective field theory. The role of concentration b is discussed in this system in detail. Results show that for a =0.4, only when the concentration b is in the region 0.60 ≥b 〉 0.34 can the ferrimagnetic behavior be seen. Otherwise, the alloy shows ferromagnetic behavior.展开更多
AIM: To investigate the correlation between C/T single nucleotide polymorphism (SNP) in the promoter of the DNA methyltransferase 3B (D/VMT3B) gene and risk for development and progression of primary hepatocellul...AIM: To investigate the correlation between C/T single nucleotide polymorphism (SNP) in the promoter of the DNA methyltransferase 3B (D/VMT3B) gene and risk for development and progression of primary hepatocellular carcinoma (HCC). METHODS: One hundred case subjects were selected consecutively from Tongji Hospital (Wuhan, China). from March to November 2006. They did not receive radiotherapy or chemotherapy for newly diagnosed and histopathologically confirmed HCC. One hundred and forty control subjects having no history of cancerous or genetic diseases were healthy volunteers to Wuhan Blood Center in the same period. Frequency was matched for sex, age, alcohol consumption and cigarette smoking status of the case subjects. C/T polymorphism of the DNMT3B promoter was analyzed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and sequencing analysis. The association between genotypes of DNMT3B and clinicopathological parameters among cases was also studied. RESULTS: The CC genotype HCC patients and controls. was not detected in both In control subjects, the frequency of TT and CT genotypes was 99.3% and 0.7% respectively, and that of T and C alleles was 99.6% and 0.4% respectively. The frequency of CT genotype was higher in HCC (3.0%). The frequency of T and C alleles was 98.5% and 1.5% respectively. However, the genotype and allelotype distribution in HCC patients was not significantly different from that in controls. CONCLUSION: C/T polymorphism is not associated with the increased risk of HCC. DNMT3B genetic polymorphism is variable in different races, ethnic groups or geographic areas. Further study is needed to clarify the role of DNMT3B SNP in the development of HCCamong other populations.展开更多
In this work,the chromium aluminum nitride(CrAlN)coatings were prepared on TC11 titanium alloy by composite magnetic field cathodic arc ion plating with controllable pulse electromagnetic combined with permanent magne...In this work,the chromium aluminum nitride(CrAlN)coatings were prepared on TC11 titanium alloy by composite magnetic field cathodic arc ion plating with controllable pulse electromagnetic combined with permanent magnet.The effects of electromagnetic frequency on the morphology,microstructure,nano-hardness and elastic modulus of the coatings were investigated by scanning electron microscope(SEM),X-ray diffraction(XRD)and nano-indenter.This paper has mainly studied the influence of CrAlN coatings which are prepared at various electromagnetic frequencies on the wear and erosion resistance through a series of wear and solid particle erosion experiments.It was found that the deposition rate of CrAlN coatings increases with the increase of electromagnetic frequency.And CrAlN coatings all preferentially grew along the(111)crystal plane.At 16.7 Hz,with the increase of pulsed electromagnetic frequency,the hardness is the highest(23.6 GPa)and the adhesion is the highest(41.5 N).In addition,the coating deposition exhibited the best wear and solid erosion resistance at 16.7 Hz and 33.3 Hz,the friction coefficient is about 0.35,and the erosion rate is about 0.2μm/g at 30°and less than 1μm/g at 90°,respectively.These results indicate that the CrAlN coating formed at an appropriate pulsed electromagnetic frequency can achieve excellent mechanical properties,wear and solid erosion resistance.展开更多
In order to develop the applications of ore tailings, the glass ceramics were prepared by using a conventional melting-quenching-sintering process. The phase component, microstructures, magnetic properties and thermal...In order to develop the applications of ore tailings, the glass ceramics were prepared by using a conventional melting-quenching-sintering process. The phase component, microstructures, magnetic properties and thermal conductivities of the prepared glass ceramics were investigated by using X-ray diffractometer, scanning electron microscopy, vibrating sample magnetometer and thermophysical properties tester, respectively. The results show that orthorhombic olivine-type phase and triclinic sunstone-type phase formed when the glass was annealed at 700 oC, the concentration of olivine-type and sunstone-type phases decreased, the spinel-type cubic phase occurred and the amount increased when the annealing temperatures increased. The magnetic properties from the cubic spinel ferrites were detected in the glass ceramics, and the related saturation magnetization increased with the annealing temperature increasing. The porous glass ceramics with magnetic property showed much lower thermal conductivity, compared with the non-magnetic porous glass-ceramic and the dense glass-ceramics.展开更多
The effects of solidification rate and excessive Fe on phase formation and magnetocaloric properties of LaFe11.6xSi1.4(x=1.1,1.2)were investigated by XRD,SEM and VSM measurements.The XRD results show that the amount o...The effects of solidification rate and excessive Fe on phase formation and magnetocaloric properties of LaFe11.6xSi1.4(x=1.1,1.2)were investigated by XRD,SEM and VSM measurements.The XRD results show that the amount of LaFeSi phase in the as-cast melt-spun ribbons prepared by a copper wheel at a speed of10m/s is less than that in the as-cast arc melting buttons with the same x values.The annealed melt-spun ribbons contain smaller amount of La(Fe,Si)13(1:13)phase than the corresponding annealed arc melting buttons.Although the melt-spun sample has finer crystalline grains ofα-Fe,as indicated by SEM analysis,its crystalline size has not reached nano-scale.Therefore,the magnetic exchange-coupling between1:13phase andα-Fe phase has not been observed in melt-spun ribbons.Further,the maximum negative magnetic entropy change(?SMax)and relative cooling power(RCP)of annealed melt-spun ribbons under a field change of0?2T are weaker than those of the corresponding annealed arc melting buttons.展开更多
Although the study of TM(Thermo Mechanics),HM(Hydraulic-Mechanics) and THM(Thermo-Hydraulic-Mechanics) coupling under a loading test have been under development,rock failure analysis under THM coupling and unloading i...Although the study of TM(Thermo Mechanics),HM(Hydraulic-Mechanics) and THM(Thermo-Hydraulic-Mechanics) coupling under a loading test have been under development,rock failure analysis under THM coupling and unloading is an emerging topic.Based on a high temperature triaxial unloading seep test for phyllite,this paper discusses the deformation and failure mechanism of phyllites under the "H M,T→H,T→M" incomplete coupling model with unloading conditions.The results indicate that the elastic modulus and initial permeability decrease and the Poisson's ratio increases with increasing temperature;the elastic modulus decreases and the Poisson's ratio and initial permeability increase with increasing water pressure.During the unloading process,rock penetrability is small at the initial elastic deformation phase,but the penetrability increases near the end of the elastic deformation phase;mechanisms involving temperature and water pressure affect penetrability differently.Phyllite failure occurs from the initial thermal damage of the rock materials,splitting and softening(which is caused by pore water pressure),and the pressure difference which is formed from the loading axial pressure and unloading confining pressure.The phyllite failure mechanism is a transtensional(tension-shearing) failure.展开更多
基金financially supported by the Key Program of National Natural Science Foundation of China(No.41530320)China Natural Science Foundation for Young Scientists(No.41404093)+1 种基金Key National Research Project of China(Nos2016YFC0303100 and 2017YFC0601900)China Natural Science Foundation(No.41774125)
文摘The airborne electromagnetic (AEM) method has a high sampling rate and survey flexibility. However, traditional numerical modeling approaches must use high-resolution physical grids to guarantee modeling accuracy, especially for complex geological structures such as anisotropic earth. This can lead to huge computational costs. To solve this problem, we propose a spectral-element (SE) method for 3D AEM anisotropic modeling, which combines the advantages of spectral and finite-element methods. Thus, the SE method has accuracy as high as that of the spectral method and the ability to model complex geology inherited from the finite-element method. The SE method can improve the modeling accuracy within discrete grids and reduce the dependence of modeling results on the grids. This helps achieve high-accuracy anisotropic AEM modeling. We first introduced a rotating tensor of anisotropic conductivity to Maxwell's equations and described the electrical field via SE basis functions based on GLL interpolation polynomials. We used the Galerkin weighted residual method to establish the linear equation system for the SE method, and we took a vertical magnetic dipole as the transmission source for our AEM modeling. We then applied fourth-order SE calculations with coarse physical grids to check the accuracy of our modeling results against a 1D semi-analytical solution for an anisotropic half-space model and verified the high accuracy of the SE. Moreover, we conducted AEM modeling for different anisotropic 3D abnormal bodies using two physical grid scales and three orders of SE to obtain the convergence conditions for different anisotropic abnormal bodies. Finally, we studied the identification of anisotropy for single anisotropic abnormal bodies, anisotropic surrounding rock, and single anisotropic abnormal body embedded in an anisotropic surrounding rock. This approach will play a key role in the inversion and interpretation of AEM data collected in regions with anisotropic geology.
文摘Objective To investigate the influence of vitamin D receptor (VDR) gene polymorphisms on susceptibility to type 1 diabetes mellitus (T1DM) in the Chinese Han population. Method One hundred and thirty-six Chinese Han people, including 54 T1DM patients and 82 unrelated healthy subjects as control were genotyped by polymerase chain reaction-restriction fragment length polymorphism for three restriction sites in the VDR gene, which were ApaI, TaqI, and BamL Results The frequency of B allele of BsmI site in VDR gene was significantly higher in T1DM patients than in healthy subjects ( P = 0. 033 ) while no difference was found between the two groups in the distribution of ApaI and TaqI polymorphisms. Conclusion The BsmI polymorphism of VDR gene may be associated with the susceptibihty to T1DM in the Chinese Han population of Beijing.
基金The project supported by Shanghai Leading Academic Discipline Project under Grant,No.T0104
文摘The magnetic behavior of the mixed ferro-ferrimagnetie alloy with (Aa Bb Cc)y D structure composed of Ising spins SA=1, SB = 5/2, SC= 2, and SD = 3/2 in the presence of the external magnetic field is investigated by the use of the effective field theory. The role of concentration b is discussed in this system in detail. Results show that for a =0.4, only when the concentration b is in the region 0.60 ≥b 〉 0.34 can the ferrimagnetic behavior be seen. Otherwise, the alloy shows ferromagnetic behavior.
文摘AIM: To investigate the correlation between C/T single nucleotide polymorphism (SNP) in the promoter of the DNA methyltransferase 3B (D/VMT3B) gene and risk for development and progression of primary hepatocellular carcinoma (HCC). METHODS: One hundred case subjects were selected consecutively from Tongji Hospital (Wuhan, China). from March to November 2006. They did not receive radiotherapy or chemotherapy for newly diagnosed and histopathologically confirmed HCC. One hundred and forty control subjects having no history of cancerous or genetic diseases were healthy volunteers to Wuhan Blood Center in the same period. Frequency was matched for sex, age, alcohol consumption and cigarette smoking status of the case subjects. C/T polymorphism of the DNMT3B promoter was analyzed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and sequencing analysis. The association between genotypes of DNMT3B and clinicopathological parameters among cases was also studied. RESULTS: The CC genotype HCC patients and controls. was not detected in both In control subjects, the frequency of TT and CT genotypes was 99.3% and 0.7% respectively, and that of T and C alleles was 99.6% and 0.4% respectively. The frequency of CT genotype was higher in HCC (3.0%). The frequency of T and C alleles was 98.5% and 1.5% respectively. However, the genotype and allelotype distribution in HCC patients was not significantly different from that in controls. CONCLUSION: C/T polymorphism is not associated with the increased risk of HCC. DNMT3B genetic polymorphism is variable in different races, ethnic groups or geographic areas. Further study is needed to clarify the role of DNMT3B SNP in the development of HCCamong other populations.
基金Projects(2017GDAS CX-0202,2017GDAS CX-0111,2018 GDAS CX-0402) supported by Guangdong Academy of Science’ Special Project of Science and Technology Development,ChinaProject(2014B070705007) supported by Guangdong Science and Technology Plan Project,China+1 种基金Project(2016A030312015) supported by Scientific Research Fund of Guangdong Province,ChinaProject(2017A070701027) supported by Guangdong Science and Technology Program,China。
文摘In this work,the chromium aluminum nitride(CrAlN)coatings were prepared on TC11 titanium alloy by composite magnetic field cathodic arc ion plating with controllable pulse electromagnetic combined with permanent magnet.The effects of electromagnetic frequency on the morphology,microstructure,nano-hardness and elastic modulus of the coatings were investigated by scanning electron microscope(SEM),X-ray diffraction(XRD)and nano-indenter.This paper has mainly studied the influence of CrAlN coatings which are prepared at various electromagnetic frequencies on the wear and erosion resistance through a series of wear and solid particle erosion experiments.It was found that the deposition rate of CrAlN coatings increases with the increase of electromagnetic frequency.And CrAlN coatings all preferentially grew along the(111)crystal plane.At 16.7 Hz,with the increase of pulsed electromagnetic frequency,the hardness is the highest(23.6 GPa)and the adhesion is the highest(41.5 N).In addition,the coating deposition exhibited the best wear and solid erosion resistance at 16.7 Hz and 33.3 Hz,the friction coefficient is about 0.35,and the erosion rate is about 0.2μm/g at 30°and less than 1μm/g at 90°,respectively.These results indicate that the CrAlN coating formed at an appropriate pulsed electromagnetic frequency can achieve excellent mechanical properties,wear and solid erosion resistance.
基金Project(51172287)supported by the National Natural Science Foundation of ChinaProject(2012-2013)supported by the Laboratory Research Fund of the State Key Laboratory of Powder Metallurgy,China
文摘In order to develop the applications of ore tailings, the glass ceramics were prepared by using a conventional melting-quenching-sintering process. The phase component, microstructures, magnetic properties and thermal conductivities of the prepared glass ceramics were investigated by using X-ray diffractometer, scanning electron microscopy, vibrating sample magnetometer and thermophysical properties tester, respectively. The results show that orthorhombic olivine-type phase and triclinic sunstone-type phase formed when the glass was annealed at 700 oC, the concentration of olivine-type and sunstone-type phases decreased, the spinel-type cubic phase occurred and the amount increased when the annealing temperatures increased. The magnetic properties from the cubic spinel ferrites were detected in the glass ceramics, and the related saturation magnetization increased with the annealing temperature increasing. The porous glass ceramics with magnetic property showed much lower thermal conductivity, compared with the non-magnetic porous glass-ceramic and the dense glass-ceramics.
基金Project (16ZB0301) supported by the Research Program of Sichuan Provincial Education Department,China
文摘The effects of solidification rate and excessive Fe on phase formation and magnetocaloric properties of LaFe11.6xSi1.4(x=1.1,1.2)were investigated by XRD,SEM and VSM measurements.The XRD results show that the amount of LaFeSi phase in the as-cast melt-spun ribbons prepared by a copper wheel at a speed of10m/s is less than that in the as-cast arc melting buttons with the same x values.The annealed melt-spun ribbons contain smaller amount of La(Fe,Si)13(1:13)phase than the corresponding annealed arc melting buttons.Although the melt-spun sample has finer crystalline grains ofα-Fe,as indicated by SEM analysis,its crystalline size has not reached nano-scale.Therefore,the magnetic exchange-coupling between1:13phase andα-Fe phase has not been observed in melt-spun ribbons.Further,the maximum negative magnetic entropy change(?SMax)and relative cooling power(RCP)of annealed melt-spun ribbons under a field change of0?2T are weaker than those of the corresponding annealed arc melting buttons.
基金supported by National Natural Science Foundation of China (Grant No. 41102189,No. 41002110 and No. 41230635)Projects of State Key Laboratory of Geohazard Prevention and Geoenvironment Protection(Grant No. SKLGP2009Z002,No. SKLGP2009Z012)Research Fund for the Doctoral Program of Higher Education of China(Grant No. 20105122110008)
文摘Although the study of TM(Thermo Mechanics),HM(Hydraulic-Mechanics) and THM(Thermo-Hydraulic-Mechanics) coupling under a loading test have been under development,rock failure analysis under THM coupling and unloading is an emerging topic.Based on a high temperature triaxial unloading seep test for phyllite,this paper discusses the deformation and failure mechanism of phyllites under the "H M,T→H,T→M" incomplete coupling model with unloading conditions.The results indicate that the elastic modulus and initial permeability decrease and the Poisson's ratio increases with increasing temperature;the elastic modulus decreases and the Poisson's ratio and initial permeability increase with increasing water pressure.During the unloading process,rock penetrability is small at the initial elastic deformation phase,but the penetrability increases near the end of the elastic deformation phase;mechanisms involving temperature and water pressure affect penetrability differently.Phyllite failure occurs from the initial thermal damage of the rock materials,splitting and softening(which is caused by pore water pressure),and the pressure difference which is formed from the loading axial pressure and unloading confining pressure.The phyllite failure mechanism is a transtensional(tension-shearing) failure.