Through investigating ten recreational marine beaches in China, we aimed to detect the occurrence of human enteric viruses in coastal bathing beaches and find a correlationship, if any, between the presence of enteric...Through investigating ten recreational marine beaches in China, we aimed to detect the occurrence of human enteric viruses in coastal bathing beaches and find a correlationship, if any, between the presence of enteric viruses in surface seawater and the concentrations of fecal coliforms, the conventional indicator of fecal pollution. In this study, twenty seawater samples were assayed for fecal coliforms and human pathogenic enteric viruses (hepatitis A viruses, rotaviruses, polioviruses) analysis. Enteric viruses were detected by RT-PCR, in 20 sample sites, 5%, 40%, 40% were positive for the presence of human hepatitis A viruses, rotaviruses, polioviruses, respectively. Seven of 20 sites are suffering from severe fecal contamination, based on traditional plate counts of fecal coliform outnumbering the established thresholds for recreation. Additionally, statistical analysis presented that no correlation was found between bacterial indicators and viruses in surface seawaters. The data confirmed that indicator bacteria in water are not reflective of the presence of enteric viruses in marine waters. Thus, current recreational water quality standards of both bacterial and viral indices should be reevaluated.展开更多
The flow through a rotating U bend duct is investigated by means of visualization. The U bend duct has a cross section of 50 mm×50 mm and a ratio of bend mean radius R c to hydraulic diameter of the duct D of ...The flow through a rotating U bend duct is investigated by means of visualization. The U bend duct has a cross section of 50 mm×50 mm and a ratio of bend mean radius R c to hydraulic diameter of the duct D of 0.65. The rotation axis is parallel with the bend axis. Three cases with rotation number of Ro=-0.2, 0 and 0.2, respectively, are studied at a Reynolds number of 100 000. The results show that the combined effect of rotation and bend curvature strongly influences the flow field, especially in the downstream region of the bend. The evident difference among the flow patterns with different rotation number shows that the secondary flow induced by Coriolis force takes an important role in determining the flow structure.展开更多
Multiple constraints for schematic road network map cartographic design are analyzed and summarized. Based on this, a set of quantitative criteria are set up and a new road network generalization method including prog...Multiple constraints for schematic road network map cartographic design are analyzed and summarized. Based on this, a set of quantitative criteria are set up and a new road network generalization method including progressive selection and displacement is proposed. Furthermore, topological checking methods for road networks are researched. Based on these constraints, the points in a road network are classified, and a satisfactory and effective schematic map is designed in a con- crete experiment while maintaining topological consistency of the road network between the original and the schematic map展开更多
Rice stripe virus (RSV) infects rice and is transmitted in a propagative manner by the small brown planthopper. How RSV enters an insect cell to initiate the infection cycle is poorly understood. Sequence analysis rev...Rice stripe virus (RSV) infects rice and is transmitted in a propagative manner by the small brown planthopper. How RSV enters an insect cell to initiate the infection cycle is poorly understood. Sequence analysis revealed that the RSV NSvc2 protein was similar to the membrane glycoproteins of several members in the family Bunyaviridae and might induce cell membrane fusion. To conveniently study the membrane fusion activity of NSvc2, we constructed cell surface display vectors for expressing Nsvc2 on the insect cell surface as the membrane glycoproteins of the enveloped viruses. Our results showed that NSvc2 was successfully expressed and displayed on the surface of insect Sf9 cells. When induced by low pH, the membrane fusion was not observed in the cells that expressed NSvc2. Additionally, the membrane fusion was also not detected when co-expressing Nsvc2 and the viral capsid protein on insect cell surface. Thus, RSV NSvc2 is probably different from the phlebovirus counterparts, which could suggest different functions. RSV might enter insect cells other than by fusion with plasma or endosome membrane.展开更多
The location, intensity and scope of concentrated leakage must be determined in order to repair earth-Dam scoured by the leakage. In this paper, firstly, heat tracer theory and distribution laws of temperature in soil...The location, intensity and scope of concentrated leakage must be determined in order to repair earth-Dam scoured by the leakage. In this paper, firstly, heat tracer theory and distribution laws of temperature in soil body with leakage are discussed. Then temperature tracer model is established according to stable heat conduction theory. In such model, the concentrated seepage passage is simplified into a circular pipe as a boundary condition. The location, scope and flow-velocity of the concentrated leakage are estimated via ichnography of the lowest temperature based on temperature data from detecting wells by quantitative computation and qualitative analysis. In case study, the distribution characteristic of temperature (including temperature data of water in reservoir, drainage pipes and tail pond) can be interpreted by this model. A modified model is also set up, applied for detected data at different cross-sections of the leakage passage, in which the temperature data are rectified according to distances from data locations to calculating section. Finally, the model is solved by numerical iterative method, and the possible error of this theoretical model is discussed. The permeability coefficient in leakage area is identical with that of normal soil in magnitude after anti-seepage repairing accomplished, which indicates this model is effective.展开更多
AIM:To investigate the feasibility and the effectiveness of ileoileostomy in the region adjacent to the ileocecal valve,which can retain the ileocecal valve in infants.METHODS:This is a retrospective review of 48 pati...AIM:To investigate the feasibility and the effectiveness of ileoileostomy in the region adjacent to the ileocecal valve,which can retain the ileocecal valve in infants.METHODS:This is a retrospective review of 48 patients who underwent ileoileostomy in the region adjacent to the ileocecal valve(group 1) and 34 patients who underwent ileocecal resections and ileotransversanastomosis(group 2).Patients were monitored for the time to flatus,resumption of eating,length of hospital stay after surgery,serum total bile acid,vitamin B12 and postoperative complications.RESULTS:The time to flatus,time until resumption of eating and post-operative length of hospital stay showed no statistically significant differences between the two groups.Serum total bile acid and vitamin B12were not significantly different between the two groups at post-operative day 1 and day 3,but were significantly decreased at 1 wk after operation in group 2.None of the patients died or suffered from stomal leak in these two groups.However,the incidence of diarrhea,intestinal infection,disturbance of acid-base balance and water-electrolytes in group 1 was lower than in group 2.CONCLUSION:Ileoileostomy in the region adjacent to the ileocecal valve is safe and results in fewer complications than ileotransversanastomosis in infants.展开更多
The Ordovician karst groundwater in the Qiligou basin is an important water supply source. This groundwater has been seriously contaminated in recent years by Cfl4 from a pesticide plant located in the recharge area. ...The Ordovician karst groundwater in the Qiligou basin is an important water supply source. This groundwater has been seriously contaminated in recent years by Cfl4 from a pesticide plant located in the recharge area. The highest concentration of CCl4 in the groundwater is 3909.2μg/L. Large scale tracer experiments were carried out to study the conveying conduits for Cfl4 in the basin on May 1-6, 2005. Nontoxic, edible glucose was used as a tracer and it was detected by spectrophotometric techniques. Well area of the basin, was employed for injecting the tracer X-61, located near the pesticide plant in the southern recharge Ten wells widely located in the groundwater runoff area were used as observing and sampling wells. The results show that the migration of the pollutants is controlled by the water hydrodynamic field and by the development of karst conduits. The tracer did not enter the up-drainage wells, X-49 and X-47, near the injection point because the water levels at these wells are higher than at the injection point. The adjacent well X-62 is close to the injection site, but the tracer reached the well after eleven hours. Wells X-43, X-59, X-58, YY-1 and X-57, located in the syncline axis runoff area, are respectively 2.5, 3.5, 4.33, 4.38 and 5.44 kilometers from the in- jection site. The time for initial appearance of tracer was 4, 4, 2, 6 and 4 hours, respectively. The maximum runoff velocity (well X-58) is over two kilometers per hour, indicating that the karst conduits are well developed along the syncline basin axis. These conduits are the main conveying conduits for groundwater and Cfl4. Closer wells were not necessarily the first to receive tracer. This shows the inhomogeneity in karst development which causes complex runoff, and pollutant migration, patterns.展开更多
It is well known that for non-linear Hamiltonian systems there exist ordered regions with quasi-periodic orbits and regions with chaotic orbits. Usually, these regions are distributed in the phase space in very compli...It is well known that for non-linear Hamiltonian systems there exist ordered regions with quasi-periodic orbits and regions with chaotic orbits. Usually, these regions are distributed in the phase space in very complicated ways, which often makes it very difficult to distinguish between them, especially when we are dealing with many degrees of freedom. Recently, a new, very fast and easy to compute indicator of the chaotic or ordered nature of orbits has been introduced by Zotos (2012), the so-called "Fast Norm Vector Indicator (FNV1)". Using the double pendulum system, in the paper we present a detailed numerical study comporting the advantages and the drawbacks of the FNVI to those of the Smaller Alignment Index (SALI), a reliable indicator of chaos and order in Hamiltonian systems. Our effort was focused both on the traditional behavior of the FNVI for regular and fully developed chaos but on the "sticky" orbits and on the quantitative criterion proposed by Zotos, too.展开更多
This paper presents a joint method of Doppler Beam Sharpen (DBS) imaging and Signal Subspace Processing (SSP) to achieve Ground Moving Target Indication(GMTI) for along- track dual-antenna airborne radar. When the err...This paper presents a joint method of Doppler Beam Sharpen (DBS) imaging and Signal Subspace Processing (SSP) to achieve Ground Moving Target Indication(GMTI) for along- track dual-antenna airborne radar. When the error of the two antennas (also refers to channels) changes pulse to pulse, the method SSP is used to precisely calibrate the two antennas’ DBS images, then to detect the ground moving targets in the difference image of the two calibrated images. The method DBS-SSP is proved to offer performance improvement on the actually measured data and simulated data.展开更多
We present a rare case of a 50-year old lady who presented with pain abdomen and bleeding per vaginum of 3 months duration. Per vaginal examination revealed an exophytic growth arising from vault. Histopathological ex...We present a rare case of a 50-year old lady who presented with pain abdomen and bleeding per vaginum of 3 months duration. Per vaginal examination revealed an exophytic growth arising from vault. Histopathological examination of the vault biopsy showed malignant neoplasm with features suggestive of carcinosarcoma of vault with immunohistochemistry showing stromal cells positive for CD10 and negative for SMA. Ki67 index was 40%-50%. She received external beam radiotherapy to pelvis 50.4 Gy/25 fractions but did not respond to the same. The lesion was not surgically resectable and hence referred to the division of medical oncology for chemotherapy. She was started on ifosphamide with cisplatin with growth factor support. It was planned to do a reassessment after 3 cycles of chemotherapy, but patient succumbed to the illness.展开更多
With the deployment of small cells and device to device communications in future heterogeneous networks,in many situations we would encounter mobile radio channels with partly blocked line of sight component,which are...With the deployment of small cells and device to device communications in future heterogeneous networks,in many situations we would encounter mobile radio channels with partly blocked line of sight component,which are well modeled by the Rician shadowed(RS) fading channel.In this paper,by the usage of Kummer transformation,a simplified representation of the RS fading channel with integral fading parameter is given.It is a finite series representation involving only exponential function and low order polynomials.This allows engineers not only the closed-form expressions for exact performance analysis over RS fading channel,but also the insights on the system design tactics.展开更多
AIM To identify whether chitinase 3-like 1(CHI3 L1) serves as a suitable biomarker for the prognosis of esophageal squamous cell carcinoma(ESCC) and to analyze this protein's cellular source.METHODS An ELISA was c...AIM To identify whether chitinase 3-like 1(CHI3 L1) serves as a suitable biomarker for the prognosis of esophageal squamous cell carcinoma(ESCC) and to analyze this protein's cellular source.METHODS An ELISA was conducted to detect the concentration of CHI3 L1 in the serum of 150 ESCC patients diagnosed between January 2001 and February 2005. The prognostic relevance of CHI3 L1 was evaluated by a Kaplan-Meier and Cox regression analysis. The immunohistochemistry was reanalyzed,and fluorescent staining was utilized to explore the cellular origins of CHI3 L1. We stimulated monocyte-derived macrophages(MDMs) with either IL-6 or the supernatant of the ESCC cell line Eca-109 and later investigated the level of CHI3 L1 by q PCR and ELISA.RESULTS The level of serum CHI3 L1 was higher in older patients(≥ 60) than in patients under the age of 60(P = 0.001). The patients with higher levels of CHI3 L1 had a significantly shorter overall survival,whereas the traditional markers,carcinoembryonic antigen and squamous cell carcinoma antigen,were less effective(P > 0.05). A multivariate Cox analysis(P = 0.001) indicated that CHI3 L1 was an independent prognostic factor for ESCC patients. Peritumoral macrophages in ESCC exhibited high levels of CHI3 L1. Interleukin-6(IL-6) and the supernatant of Eca-109 containing IL-6 stimulated MDMs to secrete CHI3 L1. The serum concentration of CHI3 L1 in the ESCC patients showed a weak correlation with the laboratory inflammatory parameters neutrophil(NEU,P = 0.045),neutrophil/lymphocyte rate(NLR,P = 0.016),and C-reactive protein(CRP,P < 0.001).CONCLUSION Our study first established a connection between the pretreated CHI3 L1 and patients with ESCC,and the serum CHI3 L1 was primarily secreted by ESCC-surrounded macrophages.展开更多
AIM: To study the association between inflammatory bowel disease (IBD) and genetic variations in eosinophil protein X (EPX) and eosinophil cationic protein (ECP). METHODS: DNA was extracted from ethylene diami...AIM: To study the association between inflammatory bowel disease (IBD) and genetic variations in eosinophil protein X (EPX) and eosinophil cationic protein (ECP). METHODS: DNA was extracted from ethylene diamine tetraacetic acid blood of 587 patients with Crohn's disease (CD), 592 with ulcerative colitis (UC) and 300 healthy subjects. The EPX405 (G 〉 C, rs2013109), ECP434 (G 〉 C, rs2073342) and ECP562 (G 〉 C, rs2233860) gene polymorphisms were analysed, by the 5'-nuclease allelic discrimination assay. For de- termination of intracellular content of EPX and ECP in granulocytes, 39 blood samples was collected and extracted with a buffer containing cetyltrimethylam- monium bromide. The intracellular content of EPX was analysed using an enzyme-linked immunosorbent as- say. The intracellular content of ECP was analysed with the UniCAP system as described by the manufacturer. Statistical tests for calculations of results were χ2 test, Fisher's exact test, ANOVA, Student-Newman-Keuls test, and Kaplan-Meier survival curve with Log-rank test for trend, the probability values of P 〈 0.05 were considered statistically significant.RESULTS: The genotype frequency for males with UC and with an age of disease onset of ≥ 45 years (n = 57) was for ECP434 and ECP562, GG = 37%, GC = 60%, CC = 4% and GG = 51%, GC = 49%, CC = 0% respectively. This was significantly different from the healthy subject's genotype frequencies of ECP434 (GG = 57%, GC = 38%, CC = 5%; P = 0.010) and ECP562 (GG = 68%, GC = 29%,CC = 3%; P = 0.009). The genotype frequencies for females, with an age of dis- ease onset of ≥ 45 years with CD (n = 62), was for the ECP434 and ECP562 genotypes GG = 37%, GC =52%, CC = 11% and GG = 48%, GC = 47% and CC = 5% respectively. This was also statistically different from healthy controls for both ECP434 (P = 0.010) and ECP562 (P = 0.013). The intracellular protein concen- tration of EPX and ECP was calculated in μg/10^6 eosi- nophils and then correlated to the EPX 405 genotypes. The protein content of EPX was highest in the patients with the CC genotype of EPX405 (GG = 4.65, GC = 5.93, and CC = 6.57) and for ECP in the patients with the GG genotype of EPX405 (GG = 2.70, GC = 2.47 and CC = 1.90). ANOVA test demonstrated a difference in intracellular protein content for EPX (P = 0.009) and ECP (P = 0.022). The age of disease onset was linked to haplotypes of the EPX405, ECP434 and ECP562 genotypes. Kaplan Maier curve showed a difference be- tween haplotype distributions for the females with CD (P = 0.003). The highest age of disease onset was seen in females with the EPX405CC, ECP434GC, ECP562CC haplotype (34 years) and the lowest in females with the EPX405GC, ECP434GC, ECP562GG haplotype (21 years). For males with UC there was also a difference between the highest and lowest age of the disease on- set (EPX405CC, ECP434CC, ECP562CC, mean 24 years vs EPX405GC, ECP434GC, ECP562GG, mean 34 years, P = 0.0009). The relative risk for UC patients with ECP434 or ECP562-GC/CC genotypes to develop dys- plasia/cancer was 2.5 (95%CI: 1.2-5.4, P = 0.01) and 2.5 (95%CI: 1.1-5.4, P = 0.02) respectively, compared to patients carrying the GG-genotypes.展开更多
Pragmatic vagueness is a manifestation that language has elasticity and is one of attributes of nature language. Pragmatic vagueness phenomenon exists in news report, law version and commerce report. Nowadays in adver...Pragmatic vagueness is a manifestation that language has elasticity and is one of attributes of nature language. Pragmatic vagueness phenomenon exists in news report, law version and commerce report. Nowadays in adverting creations, advertisers take pragmatic vagueness as the strategy in order to make the most effective to strengthen the advertising attention, memory and persuasion in the limited time and space. At the same time, the pragmatic vagueness strategy also strengthens the advertising flexibility and appropriateness, compresses information and produces advertising aesthetic effect. In most circumstances, advertising companies use pragmatic vagueness to realize their advertising purpose and pragmatic vagueness offers strangely psychological hint to customers. This paper will firstly state pragmatic vagueness and advertising activities, and then analysis the function of pragmatic vagueness in advertisements.展开更多
The detailed structures of the volcanic edifice and plumbing system of the early Permian Tarim flood basalt were investigated by three-dimensional seismic imaging. The images show that the Tarim flood basalt erupted f...The detailed structures of the volcanic edifice and plumbing system of the early Permian Tarim flood basalt were investigated by three-dimensional seismic imaging. The images show that the Tarim flood basalt erupted from central volcanoes distributed along major faults. The uppermost magma formed a single lava lobe with a volume of *0.74 km3 and an aspect ratio of 50,implying a sheet flow eruption with a high effusion rate. At the subsurface level, all central volcanoes, irrespective of size, had a separate pipe-like feeder vent. Only thirteen dikes were identified at shallow depths of \100 m below the lava surface; deeper dikes were even rarer. The pipelike plumbing system and the paucity of dilational dikes were different from the typical plumbing system of flood basalt provinces on Earth, which are normally buoyancycontrolled dike–sill networks. A gas-driven vigorous eruption can be inferred from the imaged structure, which means that the Tarim flood basalt may have carried and released a large proportion of volcanic gas, similar to some mafic volcaniclastic deposit-bearing continental flood basalt provinces.展开更多
The planning Yalong-River water transfer project will transfer 5.65 billion cubic meters water from the Yalong River into the Yellow River per year.The Yalong River will be dramatically impacted hydrologically and eco...The planning Yalong-River water transfer project will transfer 5.65 billion cubic meters water from the Yalong River into the Yellow River per year.The Yalong River will be dramatically impacted hydrologically and ecologically because more than 60% of the runoff will be diverted.An ecohydrological model was used to evaluate the impacts of the project on river corridor and wetland in this study.Schizothorax is a typical plateau river species and was used as the indicator species for assessment of the impact of water transfer project.The model simulated the habitat area of Schizothorax in the reach between the Reba Dam and the Ganzi Hydrology Station on the Yalong River.The Reba Dam,A'an Dam and Renda Dam will be constructed in the Yalong River for enhancing the water level for water diversion into the Yellow River.The velocity,channel width,runoff,and water depth will be reduced due to the water transfer,especially during flood season.The reduction in the velocity,channel width,runoff and water depth will occur mainly in the reach near the three dams and the reduction will be reduced to a minimum level in a distance about 100 km downstream of the dams.The maximum net water loss of Kasha Lake is only 1197200 m3,only 0.3% of runoff flowing into the lake.The project cannot bring adverse effect on the lake.The habitat area of Schizothorax in the Yalong River might be reduced if the water was transferred from the Reba Dam.The habitat area of this species will be reduced more than 40%.展开更多
We use induced orbit covers to define induced orbit data.By studying the space of regular functions on orbit cover,we know that the induced representation has close connection with the induced orbit datum under the me...We use induced orbit covers to define induced orbit data.By studying the space of regular functions on orbit cover,we know that the induced representation has close connection with the induced orbit datum under the meaning of Vogan’s conjecture.Therefore,when verifying Vogan’s conjecture,many cases can be reduced to the case of rigid orbit data.展开更多
基金provided by the National High Technology Research and Development Program("863"Program)of China,grant no.2006AA09Z162the National Key Scientific and Technological Project,grant no.908-01-ZH3
文摘Through investigating ten recreational marine beaches in China, we aimed to detect the occurrence of human enteric viruses in coastal bathing beaches and find a correlationship, if any, between the presence of enteric viruses in surface seawater and the concentrations of fecal coliforms, the conventional indicator of fecal pollution. In this study, twenty seawater samples were assayed for fecal coliforms and human pathogenic enteric viruses (hepatitis A viruses, rotaviruses, polioviruses) analysis. Enteric viruses were detected by RT-PCR, in 20 sample sites, 5%, 40%, 40% were positive for the presence of human hepatitis A viruses, rotaviruses, polioviruses, respectively. Seven of 20 sites are suffering from severe fecal contamination, based on traditional plate counts of fecal coliform outnumbering the established thresholds for recreation. Additionally, statistical analysis presented that no correlation was found between bacterial indicators and viruses in surface seawaters. The data confirmed that indicator bacteria in water are not reflective of the presence of enteric viruses in marine waters. Thus, current recreational water quality standards of both bacterial and viral indices should be reevaluated.
文摘The flow through a rotating U bend duct is investigated by means of visualization. The U bend duct has a cross section of 50 mm×50 mm and a ratio of bend mean radius R c to hydraulic diameter of the duct D of 0.65. The rotation axis is parallel with the bend axis. Three cases with rotation number of Ro=-0.2, 0 and 0.2, respectively, are studied at a Reynolds number of 100 000. The results show that the combined effect of rotation and bend curvature strongly influences the flow field, especially in the downstream region of the bend. The evident difference among the flow patterns with different rotation number shows that the secondary flow induced by Coriolis force takes an important role in determining the flow structure.
基金Supported by the National Natural Science Foundation of China(No.40571133).
文摘Multiple constraints for schematic road network map cartographic design are analyzed and summarized. Based on this, a set of quantitative criteria are set up and a new road network generalization method including progressive selection and displacement is proposed. Furthermore, topological checking methods for road networks are researched. Based on these constraints, the points in a road network are classified, and a satisfactory and effective schematic map is designed in a con- crete experiment while maintaining topological consistency of the road network between the original and the schematic map
基金Natural Science Foundation of China Grants (30970138)the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Rice stripe virus (RSV) infects rice and is transmitted in a propagative manner by the small brown planthopper. How RSV enters an insect cell to initiate the infection cycle is poorly understood. Sequence analysis revealed that the RSV NSvc2 protein was similar to the membrane glycoproteins of several members in the family Bunyaviridae and might induce cell membrane fusion. To conveniently study the membrane fusion activity of NSvc2, we constructed cell surface display vectors for expressing Nsvc2 on the insect cell surface as the membrane glycoproteins of the enveloped viruses. Our results showed that NSvc2 was successfully expressed and displayed on the surface of insect Sf9 cells. When induced by low pH, the membrane fusion was not observed in the cells that expressed NSvc2. Additionally, the membrane fusion was also not detected when co-expressing Nsvc2 and the viral capsid protein on insect cell surface. Thus, RSV NSvc2 is probably different from the phlebovirus counterparts, which could suggest different functions. RSV might enter insect cells other than by fusion with plasma or endosome membrane.
基金Financial support from the National Nature Science Foundation of China(50179009)National Nature Science Foundation of China for important project(50139030)
文摘The location, intensity and scope of concentrated leakage must be determined in order to repair earth-Dam scoured by the leakage. In this paper, firstly, heat tracer theory and distribution laws of temperature in soil body with leakage are discussed. Then temperature tracer model is established according to stable heat conduction theory. In such model, the concentrated seepage passage is simplified into a circular pipe as a boundary condition. The location, scope and flow-velocity of the concentrated leakage are estimated via ichnography of the lowest temperature based on temperature data from detecting wells by quantitative computation and qualitative analysis. In case study, the distribution characteristic of temperature (including temperature data of water in reservoir, drainage pipes and tail pond) can be interpreted by this model. A modified model is also set up, applied for detected data at different cross-sections of the leakage passage, in which the temperature data are rectified according to distances from data locations to calculating section. Finally, the model is solved by numerical iterative method, and the possible error of this theoretical model is discussed. The permeability coefficient in leakage area is identical with that of normal soil in magnitude after anti-seepage repairing accomplished, which indicates this model is effective.
基金Supported by National Natural Science Foundation of China,No. 81100318a grant from Nanjing Medical University,No. 2010NJMU118
文摘AIM:To investigate the feasibility and the effectiveness of ileoileostomy in the region adjacent to the ileocecal valve,which can retain the ileocecal valve in infants.METHODS:This is a retrospective review of 48 patients who underwent ileoileostomy in the region adjacent to the ileocecal valve(group 1) and 34 patients who underwent ileocecal resections and ileotransversanastomosis(group 2).Patients were monitored for the time to flatus,resumption of eating,length of hospital stay after surgery,serum total bile acid,vitamin B12 and postoperative complications.RESULTS:The time to flatus,time until resumption of eating and post-operative length of hospital stay showed no statistically significant differences between the two groups.Serum total bile acid and vitamin B12were not significantly different between the two groups at post-operative day 1 and day 3,but were significantly decreased at 1 wk after operation in group 2.None of the patients died or suffered from stomal leak in these two groups.However,the incidence of diarrhea,intestinal infection,disturbance of acid-base balance and water-electrolytes in group 1 was lower than in group 2.CONCLUSION:Ileoileostomy in the region adjacent to the ileocecal valve is safe and results in fewer complications than ileotransversanastomosis in infants.
基金Project 40373044 supported by the National Natural Science Foundation of China
文摘The Ordovician karst groundwater in the Qiligou basin is an important water supply source. This groundwater has been seriously contaminated in recent years by Cfl4 from a pesticide plant located in the recharge area. The highest concentration of CCl4 in the groundwater is 3909.2μg/L. Large scale tracer experiments were carried out to study the conveying conduits for Cfl4 in the basin on May 1-6, 2005. Nontoxic, edible glucose was used as a tracer and it was detected by spectrophotometric techniques. Well area of the basin, was employed for injecting the tracer X-61, located near the pesticide plant in the southern recharge Ten wells widely located in the groundwater runoff area were used as observing and sampling wells. The results show that the migration of the pollutants is controlled by the water hydrodynamic field and by the development of karst conduits. The tracer did not enter the up-drainage wells, X-49 and X-47, near the injection point because the water levels at these wells are higher than at the injection point. The adjacent well X-62 is close to the injection site, but the tracer reached the well after eleven hours. Wells X-43, X-59, X-58, YY-1 and X-57, located in the syncline axis runoff area, are respectively 2.5, 3.5, 4.33, 4.38 and 5.44 kilometers from the in- jection site. The time for initial appearance of tracer was 4, 4, 2, 6 and 4 hours, respectively. The maximum runoff velocity (well X-58) is over two kilometers per hour, indicating that the karst conduits are well developed along the syncline basin axis. These conduits are the main conveying conduits for groundwater and Cfl4. Closer wells were not necessarily the first to receive tracer. This shows the inhomogeneity in karst development which causes complex runoff, and pollutant migration, patterns.
文摘It is well known that for non-linear Hamiltonian systems there exist ordered regions with quasi-periodic orbits and regions with chaotic orbits. Usually, these regions are distributed in the phase space in very complicated ways, which often makes it very difficult to distinguish between them, especially when we are dealing with many degrees of freedom. Recently, a new, very fast and easy to compute indicator of the chaotic or ordered nature of orbits has been introduced by Zotos (2012), the so-called "Fast Norm Vector Indicator (FNV1)". Using the double pendulum system, in the paper we present a detailed numerical study comporting the advantages and the drawbacks of the FNVI to those of the Smaller Alignment Index (SALI), a reliable indicator of chaos and order in Hamiltonian systems. Our effort was focused both on the traditional behavior of the FNVI for regular and fully developed chaos but on the "sticky" orbits and on the quantitative criterion proposed by Zotos, too.
文摘This paper presents a joint method of Doppler Beam Sharpen (DBS) imaging and Signal Subspace Processing (SSP) to achieve Ground Moving Target Indication(GMTI) for along- track dual-antenna airborne radar. When the error of the two antennas (also refers to channels) changes pulse to pulse, the method SSP is used to precisely calibrate the two antennas’ DBS images, then to detect the ground moving targets in the difference image of the two calibrated images. The method DBS-SSP is proved to offer performance improvement on the actually measured data and simulated data.
文摘We present a rare case of a 50-year old lady who presented with pain abdomen and bleeding per vaginum of 3 months duration. Per vaginal examination revealed an exophytic growth arising from vault. Histopathological examination of the vault biopsy showed malignant neoplasm with features suggestive of carcinosarcoma of vault with immunohistochemistry showing stromal cells positive for CD10 and negative for SMA. Ki67 index was 40%-50%. She received external beam radiotherapy to pelvis 50.4 Gy/25 fractions but did not respond to the same. The lesion was not surgically resectable and hence referred to the division of medical oncology for chemotherapy. She was started on ifosphamide with cisplatin with growth factor support. It was planned to do a reassessment after 3 cycles of chemotherapy, but patient succumbed to the illness.
基金sponsored by the National Natural Science Foundation of China under grant No.61171089the Training Program of the Major Research Plan of the National Natural Science Foundation of China under grant No.91438104
文摘With the deployment of small cells and device to device communications in future heterogeneous networks,in many situations we would encounter mobile radio channels with partly blocked line of sight component,which are well modeled by the Rician shadowed(RS) fading channel.In this paper,by the usage of Kummer transformation,a simplified representation of the RS fading channel with integral fading parameter is given.It is a finite series representation involving only exponential function and low order polynomials.This allows engineers not only the closed-form expressions for exact performance analysis over RS fading channel,but also the insights on the system design tactics.
文摘AIM To identify whether chitinase 3-like 1(CHI3 L1) serves as a suitable biomarker for the prognosis of esophageal squamous cell carcinoma(ESCC) and to analyze this protein's cellular source.METHODS An ELISA was conducted to detect the concentration of CHI3 L1 in the serum of 150 ESCC patients diagnosed between January 2001 and February 2005. The prognostic relevance of CHI3 L1 was evaluated by a Kaplan-Meier and Cox regression analysis. The immunohistochemistry was reanalyzed,and fluorescent staining was utilized to explore the cellular origins of CHI3 L1. We stimulated monocyte-derived macrophages(MDMs) with either IL-6 or the supernatant of the ESCC cell line Eca-109 and later investigated the level of CHI3 L1 by q PCR and ELISA.RESULTS The level of serum CHI3 L1 was higher in older patients(≥ 60) than in patients under the age of 60(P = 0.001). The patients with higher levels of CHI3 L1 had a significantly shorter overall survival,whereas the traditional markers,carcinoembryonic antigen and squamous cell carcinoma antigen,were less effective(P > 0.05). A multivariate Cox analysis(P = 0.001) indicated that CHI3 L1 was an independent prognostic factor for ESCC patients. Peritumoral macrophages in ESCC exhibited high levels of CHI3 L1. Interleukin-6(IL-6) and the supernatant of Eca-109 containing IL-6 stimulated MDMs to secrete CHI3 L1. The serum concentration of CHI3 L1 in the ESCC patients showed a weak correlation with the laboratory inflammatory parameters neutrophil(NEU,P = 0.045),neutrophil/lymphocyte rate(NLR,P = 0.016),and C-reactive protein(CRP,P < 0.001).CONCLUSION Our study first established a connection between the pretreated CHI3 L1 and patients with ESCC,and the serum CHI3 L1 was primarily secreted by ESCC-surrounded macrophages.
基金Supported by Grants from the Swedish Research Council-Medicinethe Hedlunds Foundation and from the Medical Faculty,Uppsala University,Uppsala,Sweden
文摘AIM: To study the association between inflammatory bowel disease (IBD) and genetic variations in eosinophil protein X (EPX) and eosinophil cationic protein (ECP). METHODS: DNA was extracted from ethylene diamine tetraacetic acid blood of 587 patients with Crohn's disease (CD), 592 with ulcerative colitis (UC) and 300 healthy subjects. The EPX405 (G 〉 C, rs2013109), ECP434 (G 〉 C, rs2073342) and ECP562 (G 〉 C, rs2233860) gene polymorphisms were analysed, by the 5'-nuclease allelic discrimination assay. For de- termination of intracellular content of EPX and ECP in granulocytes, 39 blood samples was collected and extracted with a buffer containing cetyltrimethylam- monium bromide. The intracellular content of EPX was analysed using an enzyme-linked immunosorbent as- say. The intracellular content of ECP was analysed with the UniCAP system as described by the manufacturer. Statistical tests for calculations of results were χ2 test, Fisher's exact test, ANOVA, Student-Newman-Keuls test, and Kaplan-Meier survival curve with Log-rank test for trend, the probability values of P 〈 0.05 were considered statistically significant.RESULTS: The genotype frequency for males with UC and with an age of disease onset of ≥ 45 years (n = 57) was for ECP434 and ECP562, GG = 37%, GC = 60%, CC = 4% and GG = 51%, GC = 49%, CC = 0% respectively. This was significantly different from the healthy subject's genotype frequencies of ECP434 (GG = 57%, GC = 38%, CC = 5%; P = 0.010) and ECP562 (GG = 68%, GC = 29%,CC = 3%; P = 0.009). The genotype frequencies for females, with an age of dis- ease onset of ≥ 45 years with CD (n = 62), was for the ECP434 and ECP562 genotypes GG = 37%, GC =52%, CC = 11% and GG = 48%, GC = 47% and CC = 5% respectively. This was also statistically different from healthy controls for both ECP434 (P = 0.010) and ECP562 (P = 0.013). The intracellular protein concen- tration of EPX and ECP was calculated in μg/10^6 eosi- nophils and then correlated to the EPX 405 genotypes. The protein content of EPX was highest in the patients with the CC genotype of EPX405 (GG = 4.65, GC = 5.93, and CC = 6.57) and for ECP in the patients with the GG genotype of EPX405 (GG = 2.70, GC = 2.47 and CC = 1.90). ANOVA test demonstrated a difference in intracellular protein content for EPX (P = 0.009) and ECP (P = 0.022). The age of disease onset was linked to haplotypes of the EPX405, ECP434 and ECP562 genotypes. Kaplan Maier curve showed a difference be- tween haplotype distributions for the females with CD (P = 0.003). The highest age of disease onset was seen in females with the EPX405CC, ECP434GC, ECP562CC haplotype (34 years) and the lowest in females with the EPX405GC, ECP434GC, ECP562GG haplotype (21 years). For males with UC there was also a difference between the highest and lowest age of the disease on- set (EPX405CC, ECP434CC, ECP562CC, mean 24 years vs EPX405GC, ECP434GC, ECP562GG, mean 34 years, P = 0.0009). The relative risk for UC patients with ECP434 or ECP562-GC/CC genotypes to develop dys- plasia/cancer was 2.5 (95%CI: 1.2-5.4, P = 0.01) and 2.5 (95%CI: 1.1-5.4, P = 0.02) respectively, compared to patients carrying the GG-genotypes.
文摘Pragmatic vagueness is a manifestation that language has elasticity and is one of attributes of nature language. Pragmatic vagueness phenomenon exists in news report, law version and commerce report. Nowadays in adverting creations, advertisers take pragmatic vagueness as the strategy in order to make the most effective to strengthen the advertising attention, memory and persuasion in the limited time and space. At the same time, the pragmatic vagueness strategy also strengthens the advertising flexibility and appropriateness, compresses information and produces advertising aesthetic effect. In most circumstances, advertising companies use pragmatic vagueness to realize their advertising purpose and pragmatic vagueness offers strangely psychological hint to customers. This paper will firstly state pragmatic vagueness and advertising activities, and then analysis the function of pragmatic vagueness in advertisements.
基金supported by the National Basic Research Program of China(2010CB808906)the National Natural Science Foundation of China(41272368)to WT
文摘The detailed structures of the volcanic edifice and plumbing system of the early Permian Tarim flood basalt were investigated by three-dimensional seismic imaging. The images show that the Tarim flood basalt erupted from central volcanoes distributed along major faults. The uppermost magma formed a single lava lobe with a volume of *0.74 km3 and an aspect ratio of 50,implying a sheet flow eruption with a high effusion rate. At the subsurface level, all central volcanoes, irrespective of size, had a separate pipe-like feeder vent. Only thirteen dikes were identified at shallow depths of \100 m below the lava surface; deeper dikes were even rarer. The pipelike plumbing system and the paucity of dilational dikes were different from the typical plumbing system of flood basalt provinces on Earth, which are normally buoyancycontrolled dike–sill networks. A gas-driven vigorous eruption can be inferred from the imaged structure, which means that the Tarim flood basalt may have carried and released a large proportion of volcanic gas, similar to some mafic volcaniclastic deposit-bearing continental flood basalt provinces.
基金supported by the National Natural Science Foundation of China (Grant Nos. 51027006,51109224)the National Key Basic Research Program of China ("973" Program) (Grant No. 2010CB951102)the National Key Project of Scientific and Technical Supporting Program (Grant No. 2006BAB04A08)
文摘The planning Yalong-River water transfer project will transfer 5.65 billion cubic meters water from the Yalong River into the Yellow River per year.The Yalong River will be dramatically impacted hydrologically and ecologically because more than 60% of the runoff will be diverted.An ecohydrological model was used to evaluate the impacts of the project on river corridor and wetland in this study.Schizothorax is a typical plateau river species and was used as the indicator species for assessment of the impact of water transfer project.The model simulated the habitat area of Schizothorax in the reach between the Reba Dam and the Ganzi Hydrology Station on the Yalong River.The Reba Dam,A'an Dam and Renda Dam will be constructed in the Yalong River for enhancing the water level for water diversion into the Yellow River.The velocity,channel width,runoff,and water depth will be reduced due to the water transfer,especially during flood season.The reduction in the velocity,channel width,runoff and water depth will occur mainly in the reach near the three dams and the reduction will be reduced to a minimum level in a distance about 100 km downstream of the dams.The maximum net water loss of Kasha Lake is only 1197200 m3,only 0.3% of runoff flowing into the lake.The project cannot bring adverse effect on the lake.The habitat area of Schizothorax in the Yalong River might be reduced if the water was transferred from the Reba Dam.The habitat area of this species will be reduced more than 40%.
基金supported by National Natural Science Foundation of China(Grant No.10971103)
文摘We use induced orbit covers to define induced orbit data.By studying the space of regular functions on orbit cover,we know that the induced representation has close connection with the induced orbit datum under the meaning of Vogan’s conjecture.Therefore,when verifying Vogan’s conjecture,many cases can be reduced to the case of rigid orbit data.