患者女,59岁,双下肢反复疼痛1个月;1年前接受腹膜后肿物切除术,病理诊断为弥漫大B细胞淋巴瘤(diffuse large Bcelllymphoma,DLBCL)(非生发中心来源),术后接受6个疗程R-CHOP方案化学治疗。查体:下腹部见14cm切口瘢痕,愈合良好;双下肢活...患者女,59岁,双下肢反复疼痛1个月;1年前接受腹膜后肿物切除术,病理诊断为弥漫大B细胞淋巴瘤(diffuse large Bcelllymphoma,DLBCL)(非生发中心来源),术后接受6个疗程R-CHOP方案化学治疗。查体:下腹部见14cm切口瘢痕,愈合良好;双下肢活动稍受限,拉塞格征阳性。展开更多
Objective: The aim of our study was to investigate the treatment of recurrent central nervous system lymphoma. Methods: A case of recurrent central nervous system lymphoma in a 46-year-old male was treated with temo...Objective: The aim of our study was to investigate the treatment of recurrent central nervous system lymphoma. Methods: A case of recurrent central nervous system lymphoma in a 46-year-old male was treated with temozolomide 150 mg/m2 per day for 5 days; rituximab 750 mg/m2 on dl and d8, injected from Ommaya capsule to lateral ventricle, cycles were repeated every 28 days. Results: The patient achieved complete remission and the side effects was light after the treatment. Conclusion: Using this therapy method had certain curative effect on recurrent central nervous system lymphoma. Further studies should be needed on its indication.展开更多
文摘患者女,59岁,双下肢反复疼痛1个月;1年前接受腹膜后肿物切除术,病理诊断为弥漫大B细胞淋巴瘤(diffuse large Bcelllymphoma,DLBCL)(非生发中心来源),术后接受6个疗程R-CHOP方案化学治疗。查体:下腹部见14cm切口瘢痕,愈合良好;双下肢活动稍受限,拉塞格征阳性。
文摘Objective: The aim of our study was to investigate the treatment of recurrent central nervous system lymphoma. Methods: A case of recurrent central nervous system lymphoma in a 46-year-old male was treated with temozolomide 150 mg/m2 per day for 5 days; rituximab 750 mg/m2 on dl and d8, injected from Ommaya capsule to lateral ventricle, cycles were repeated every 28 days. Results: The patient achieved complete remission and the side effects was light after the treatment. Conclusion: Using this therapy method had certain curative effect on recurrent central nervous system lymphoma. Further studies should be needed on its indication.