设计了便携式离子电渗装置 ,采用石墨材料作电极 ,可以输出恒定的和不同频率、不同波形的脉冲直流电流 ,电渗时间和停药时间可以预先设置。研制了 L HRH的 PVA水凝胶贴片 ,进行了大鼠在体恒定和脉冲离子电渗透皮给药 ,结果表明离子电渗...设计了便携式离子电渗装置 ,采用石墨材料作电极 ,可以输出恒定的和不同频率、不同波形的脉冲直流电流 ,电渗时间和停药时间可以预先设置。研制了 L HRH的 PVA水凝胶贴片 ,进行了大鼠在体恒定和脉冲离子电渗透皮给药 ,结果表明离子电渗技术可以促进凝胶贴片中 L HRH的透皮转运 ,持续实验的 2 4h内 ,血清中可以维持平稳的 L HRH水平 ,从而诱导大鼠体内分泌的 L H水平有较明显的提高。通过电场的反转和中断可以模拟体内周期性的 L HRH分泌。展开更多
In order to improve the wear resistance of titanium alloys,the potential of the plasma nitriding process with a cathode assiting discharge setup was examined.Ti6Al4V alloy was nitrided by the cathode assiting discharg...In order to improve the wear resistance of titanium alloys,the potential of the plasma nitriding process with a cathode assiting discharge setup was examined.Ti6Al4V alloy was nitrided by the cathode assiting discharge nitriding(CAN) and conventional DC plasma nitriding(CPN) methods,respectively.The micro-topography,phase composition and cross-sectional microhardness distribution of two nitriding layers were studied comparatively.The sliding wear resistance of the nitriding layers was examined by a ball-on-disk test against Si3N4 balls.The results indicated that the surface roughness Ra of the CAN layer was about 1 order less than that of the CPN layer.In addition,the CAN surfaces possessed significantly greater wear resistance than the CPN layer at higher loads,and increased the wear resistance of Ti6Al4V alloy by about 2 orders due to the higher loading bearing ability,higher rate of TiN phase,greater surface microhardness and bigger microhardness improving depth.This is because the double glow discharge effect in CAN strengthened the density of the active nitrogen atoms and the nitriding efficiency.Moreover,the ion bombardment effect on the surface of the nitriding titanium alloy was reduced obviously.展开更多
文摘设计了便携式离子电渗装置 ,采用石墨材料作电极 ,可以输出恒定的和不同频率、不同波形的脉冲直流电流 ,电渗时间和停药时间可以预先设置。研制了 L HRH的 PVA水凝胶贴片 ,进行了大鼠在体恒定和脉冲离子电渗透皮给药 ,结果表明离子电渗技术可以促进凝胶贴片中 L HRH的透皮转运 ,持续实验的 2 4h内 ,血清中可以维持平稳的 L HRH水平 ,从而诱导大鼠体内分泌的 L H水平有较明显的提高。通过电场的反转和中断可以模拟体内周期性的 L HRH分泌。
基金supported by the National Natural Science Foundation of China (Grant Nos. 51171154,51101127)
文摘In order to improve the wear resistance of titanium alloys,the potential of the plasma nitriding process with a cathode assiting discharge setup was examined.Ti6Al4V alloy was nitrided by the cathode assiting discharge nitriding(CAN) and conventional DC plasma nitriding(CPN) methods,respectively.The micro-topography,phase composition and cross-sectional microhardness distribution of two nitriding layers were studied comparatively.The sliding wear resistance of the nitriding layers was examined by a ball-on-disk test against Si3N4 balls.The results indicated that the surface roughness Ra of the CAN layer was about 1 order less than that of the CPN layer.In addition,the CAN surfaces possessed significantly greater wear resistance than the CPN layer at higher loads,and increased the wear resistance of Ti6Al4V alloy by about 2 orders due to the higher loading bearing ability,higher rate of TiN phase,greater surface microhardness and bigger microhardness improving depth.This is because the double glow discharge effect in CAN strengthened the density of the active nitrogen atoms and the nitriding efficiency.Moreover,the ion bombardment effect on the surface of the nitriding titanium alloy was reduced obviously.
