[ Objective] The aim of this study was to evaluate the clinical effect of the inactivated vaccine in oil emulsion against Newcastle disease and Fowl cholera, and provide conditions for combined prevention and control ...[ Objective] The aim of this study was to evaluate the clinical effect of the inactivated vaccine in oil emulsion against Newcastle disease and Fowl cholera, and provide conditions for combined prevention and control of Newcastle disease and Fowl cholera. [ Method] The mixture of avian pasteurella multocida （type A） virulent strain 1502 and Newcastle disease virus attenuated strain La Sota was prepared into five batches of the inactivated vaccine in oil emulsion to use in the field test for assessing its safety and effects on immune protection of chicken, duck and goose. [ Result] The field safety test showed that there was no adverse reaction in the vaccinated chickens, ducks and geese. The field test of immune effect for chickens suggested that the titers of hemagglutination inhibition antibody for Nescastle disease virus （ ND-HI ） in 7 - 14 day- old chickens and 60 -90 day-old young chickens were 2 -3 log2 higher than the control group after being vaccinated for 3 weeks, which could last for more than 4 months. The protection rate against avian pasteurella multocida was over 75.0% and its immune effect could last for 6 months. The field test of immune effect for duck and goose indicated that the titers of ND-HI antibody were all higher than 4.2 log2 in vaccinated ducks and geese while lower than 2 log2 in the control group after being vaccinated for 3 weeks. The protection rate against avian pasteurella multocida in vaccinated ducks and geese was higher than 75.0% and 62.5% respectively. [ Conclusion] The binary vaccine is safe for poultry and has good immune effects.展开更多
Vaccines are used in integrated control strategies to guard poultry against H5N1 high-pathogenicity avian influenza （AI）. This study was to evaluate the efficacy of AI vaccine against AI in poultry. About 400 serum ...Vaccines are used in integrated control strategies to guard poultry against H5N1 high-pathogenicity avian influenza （AI）. This study was to evaluate the efficacy of AI vaccine against AI in poultry. About 400 serum samples were collected from the selected 130 farms located at Rajshahi region, Bangladesh. The study was carried out from January, 2013 to January, 2015. The AI vaccine titres were compared in different breed of layer, environmental temperature, feed and egg production. Result showed that the value of titres （mean ± SD） in Hyline brown, Hyline white, Bovans white and Novogen white were 6.71 ± 0.05, 6.67 ± 0.06, 6.79 ± 0.03 and 6.43 ± 0.04, respectively. The highest serum antibody titres were 6.61 ± 0.24 against AI antibody in 〉 26 ℃ environment temperature. The highest and lowest serum antibody value of AI against feed brand （nutrient） were 7.75 ± 0.08 and 5.58 ± 0.22 for Aftab and Quality brand feed, respectively.展开更多
文摘[ Objective] The aim of this study was to evaluate the clinical effect of the inactivated vaccine in oil emulsion against Newcastle disease and Fowl cholera, and provide conditions for combined prevention and control of Newcastle disease and Fowl cholera. [ Method] The mixture of avian pasteurella multocida （type A） virulent strain 1502 and Newcastle disease virus attenuated strain La Sota was prepared into five batches of the inactivated vaccine in oil emulsion to use in the field test for assessing its safety and effects on immune protection of chicken, duck and goose. [ Result] The field safety test showed that there was no adverse reaction in the vaccinated chickens, ducks and geese. The field test of immune effect for chickens suggested that the titers of hemagglutination inhibition antibody for Nescastle disease virus （ ND-HI ） in 7 - 14 day- old chickens and 60 -90 day-old young chickens were 2 -3 log2 higher than the control group after being vaccinated for 3 weeks, which could last for more than 4 months. The protection rate against avian pasteurella multocida was over 75.0% and its immune effect could last for 6 months. The field test of immune effect for duck and goose indicated that the titers of ND-HI antibody were all higher than 4.2 log2 in vaccinated ducks and geese while lower than 2 log2 in the control group after being vaccinated for 3 weeks. The protection rate against avian pasteurella multocida in vaccinated ducks and geese was higher than 75.0% and 62.5% respectively. [ Conclusion] The binary vaccine is safe for poultry and has good immune effects.
文摘Vaccines are used in integrated control strategies to guard poultry against H5N1 high-pathogenicity avian influenza （AI）. This study was to evaluate the efficacy of AI vaccine against AI in poultry. About 400 serum samples were collected from the selected 130 farms located at Rajshahi region, Bangladesh. The study was carried out from January, 2013 to January, 2015. The AI vaccine titres were compared in different breed of layer, environmental temperature, feed and egg production. Result showed that the value of titres （mean ± SD） in Hyline brown, Hyline white, Bovans white and Novogen white were 6.71 ± 0.05, 6.67 ± 0.06, 6.79 ± 0.03 and 6.43 ± 0.04, respectively. The highest serum antibody titres were 6.61 ± 0.24 against AI antibody in 〉 26 ℃ environment temperature. The highest and lowest serum antibody value of AI against feed brand （nutrient） were 7.75 ± 0.08 and 5.58 ± 0.22 for Aftab and Quality brand feed, respectively.
