成长之美,培育之乐——浅谈我园的“种子文化”

近年来，我园提出了“种子文化”的理念——即把每个孩子都视为一颗珍贵的种子，种子的成长需要肥沃的土壤，需要阳光、空气、水等一切生长要素。我们将蕴含童趣的物质文化视为种子成长的肥沃土壤，将彰显和谐的精神文化视为种子成长的各类生长要素，以此来阐述种子的成长之美与园丁的培育之乐!

种子的成长

“孩子。离开后．要努力吸收你周围的养分，努力成长．成为一颗高大的白杨树。” 这是小种子听到妈妈说的最后一句话，之后．她就被小鸟带走了．

制度创新:只为人的发展

制度是学校文化的基石,文化立校需要以制度创新为抓手。在学校各项制度进行修正、完善与革新时,需要唤醒每一个人内心成长的"种子",实现每一个人的参与合作与智慧共享,形成自己的文化表达和实践样式,这样才能建设属于自己的文化,实现文化立校。

Effects of the anti-tumor composition ofthe acetoacetate extract of vitex negundoseed on the growth of human cervical carcinomaxenografts in nude mice

Objective： The aim of our study was to investigate the effects of the anti-tumor composition of the acetoacetate extract of Vitex Negundo Seed （EVn-50） on the growth of human cervical carcinoma HeLa cells xenografts in nude mica and its possible molecular mechanism. Methods： Models of human cervical cancer HeLa cells xenografts transplanted subcuta- neously in nude mice were established and randomly divided into 7 groups （each group including 5 nude mice）： saline group, Taxol group, EVn-50 group, comp-6 group, comp-7 group, comp-8 group and comp-10 group. The volume and weight of Xe- nograts were observed and compared. The alteration of the weight of nude mice, and the change of serum levels ofLDH, ALT, Cr and WBC counts were examined and compared. The apoptotic rate of human cervical carcinoma HeLa cells xenografts was analyzed by FCM. The expressions of P53 and Bcl-2 proteins of HeLa cells xenografts were determined by Western blot- ting. Results： EVn-50 and its fractionated extracts could significantly suppress the increasing volume and weight of human cervical carcinoma HeLa cells xenografts in nude mice models in time-dependent manner, yet had no significant effect on the weight of nude mice, the serum levels of LDH, ALT, Cr and WBC were counted. When the xenografts were treated with EVn-50 and its fractionated extracts for 16 days, the apoptotic rate of xenografts cells were significantly increased, and the expression of P53 protein was up-regulated and protein level of Bcl-2 was decreased. Conclusion： EVn-50 and its fractionated extracts could suppress the growth of human cervical carcinoma HeLa cells xenografts in nude mice, which may be related to its pro- motion on xenografts cells apoptosis through down-regulation of Bcl-2 expressionPand activation of P53 expression.

Herbicidal Activities of Seven Native Plants on the Germination and Growth of Phalaris minor, Echinochloa crusgalli, Portulaca oleracea and Lactuca sativa

Plant extracts could turn out to be herbicides used in weed control. We evaluated the herbicidal effect of seven plants from the Al-Qassim Region of Saudi Arabia on germination and growth of Phalaris minor, Echinochloa crusgalli, Portulaca oleracea and Lactuca sativa. In the laboratory, plant extracts at 5, 10, 20 and 40 g/L inhibited the germination and seedling growth of test seeds. P. minor and P. oleracea were more sensitive to the extracts than L. sativa and E. crusgalli. The germination of either P. minor or P. oleracea were completely inhibited by Prosopisjuliflora at 10 g/L and by Rumex vesicarius and Teucrium baccatus at 20 g/L. Extract of Pulicaria undulate completely inhibited germination of target seeds at concentrations ranged from l 0 g/L to 40 g/L. The rank order of bioactivity was Prosopis jul（17ora 〉 Pulicaria undulata 〉 Rumex vesicarius 〉 Withania somnifera 〉 Teucrium baccatus 〉 Artemisia monosperma 〉 Anvillea garcinii. In the greenhouse trial, the extracts of seven plant species at 30, 60 and 90 g/L reduced growth of six-weeks-old target plants. Anvillea garcinii and Prosopisjuliflora showed the greatest effects. At 90 g/L, the reduction in the growth of target species reached between 20% and 30% for Anvillea garcinii and between I 1% and 25% for Prosopis juliflora. Overall, Prosopis juliflora, Pulicaria undulata, Anvillea garcinii and Rumex vesicarius had potential for use as natural herbicides or for development as novel plant-derived herbicides.