Ningza No.21, a new hybrid rapeseed cultivar, was used as the test mate-rial in this study. The common planting models in large-scale production （3 trans-planting models and 2 direct-seeding models） were adopted. Ba...Ningza No.21, a new hybrid rapeseed cultivar, was used as the test mate-rial in this study. The common planting models in large-scale production （3 trans-planting models and 2 direct-seeding models） were adopted. Based on the high-yield cultivation, the yield and economic benefits of different planting models were investi-gated. ln addition, the labor costs, agricultural production materials costs and agri-cultural machinery costs of different planting model were analyzed to explore the low-costs and high-economic benefits planting model. The results showed the yields of the 5 planting models were al relatively high with average yield of 3 282.30 kg/hm2, ranging from 2 899.50 to 3 642.00 kg/hm2. Although the average yield and output value of transplanting models were higher than that of direct-seedling models by 429.25 kg/hm2 and 2 189.18 yuan/hm2 respectively, the production costs of trans-planting models were higher than that of direct-seedling model by 2 098.81 yuan/hm2 and the economic benefits were basical y equal. Among the costs of rapeseed pro-duction, the labor costs accounted for more than 60%. ln the labor costs, the har-vesting labor costs represented about 50%. Therefore, under current production con-ditions, the direct seeding and mechanized harvesting should be adopted in the rapeseed production to reduce production costs and improve economic benefits.展开更多
Filgrastim is used to accelerate hematopoietic recovery after ABMT （allogeneic bone marrow transplantation）. Its impact on the total cost of patient care remains to be explored. We therefore undertook a cost effecti...Filgrastim is used to accelerate hematopoietic recovery after ABMT （allogeneic bone marrow transplantation）. Its impact on the total cost of patient care remains to be explored. We therefore undertook a cost effectiveness analysis in the context of a randomized single blinded clinical trial of Filgrastim versus placebo in post ABMT. A primary endpoint, duration of myelosuppression, and three secondary end points （number of days of fever, length of hospital stay, survival at one hundred days） were used to assess efficacy. Direct costs were evaluated and allowed the calculation of the ICER （incremental cost-effectiveness ratios） for the major endpoint of the trial. Sixteen patients were included in the study. The duration of myelosuppression was significantly decreased in the Filgrastim arm with medians of 15 days vs. 19 days in the placebo arm （p = 0.023）. Cost analysis showed no statistically significant difference between the two arms. According to the calculation of ICER, Filgrastim was more costly and more effective than placebo for the number of days of aplasia avoided and the number of days with fever avoided. Placebo strictly dominated filgrastim for days of hospitalization avoided. Filgrastim has proven effective in reducing the duration of aplasia without increasing costs.展开更多
基金Supported by National Key Technology Research and Development Program(2010BAD01B06)Jiangsu Province Science and Technology Support Program(BE2012327)Jiangsu Agricultural Science and Technology Innovation Fund(CX(14)2003)~~
文摘Ningza No.21, a new hybrid rapeseed cultivar, was used as the test mate-rial in this study. The common planting models in large-scale production （3 trans-planting models and 2 direct-seeding models） were adopted. Based on the high-yield cultivation, the yield and economic benefits of different planting models were investi-gated. ln addition, the labor costs, agricultural production materials costs and agri-cultural machinery costs of different planting model were analyzed to explore the low-costs and high-economic benefits planting model. The results showed the yields of the 5 planting models were al relatively high with average yield of 3 282.30 kg/hm2, ranging from 2 899.50 to 3 642.00 kg/hm2. Although the average yield and output value of transplanting models were higher than that of direct-seedling models by 429.25 kg/hm2 and 2 189.18 yuan/hm2 respectively, the production costs of trans-planting models were higher than that of direct-seedling model by 2 098.81 yuan/hm2 and the economic benefits were basical y equal. Among the costs of rapeseed pro-duction, the labor costs accounted for more than 60%. ln the labor costs, the har-vesting labor costs represented about 50%. Therefore, under current production con-ditions, the direct seeding and mechanized harvesting should be adopted in the rapeseed production to reduce production costs and improve economic benefits.
文摘Filgrastim is used to accelerate hematopoietic recovery after ABMT （allogeneic bone marrow transplantation）. Its impact on the total cost of patient care remains to be explored. We therefore undertook a cost effectiveness analysis in the context of a randomized single blinded clinical trial of Filgrastim versus placebo in post ABMT. A primary endpoint, duration of myelosuppression, and three secondary end points （number of days of fever, length of hospital stay, survival at one hundred days） were used to assess efficacy. Direct costs were evaluated and allowed the calculation of the ICER （incremental cost-effectiveness ratios） for the major endpoint of the trial. Sixteen patients were included in the study. The duration of myelosuppression was significantly decreased in the Filgrastim arm with medians of 15 days vs. 19 days in the placebo arm （p = 0.023）. Cost analysis showed no statistically significant difference between the two arms. According to the calculation of ICER, Filgrastim was more costly and more effective than placebo for the number of days of aplasia avoided and the number of days with fever avoided. Placebo strictly dominated filgrastim for days of hospitalization avoided. Filgrastim has proven effective in reducing the duration of aplasia without increasing costs.
