Optimization of Chromatographic Conditions for Detecting Ellagic Acid in Pomegranate Peels Using HPLC Method

[Objective] This study aimed to optimize the chromatographic conditions for detecting ellagic acid in pomegranate peels using HPLC method. [Method] By using 0.2 mg/ml ellagic acid standard solution, on the basis of single-factor experiment and orthogonal experiment, chromatographic conditions （mobile phase ratio, flow rate, col- umn temperature） for detecting ellagic acid using HPLC were optimized. Based on the optimal chromatographic conditions, the ellagic acid content in experimental pomegranate peels was determined. [Resull] The optimal chromatographic conditions for detecting ellagic acid in pomegranate peels using HPLC method are： 1.2% phos- phoric acid：acetonitrile=85：15, column temperature of 35 ℃, and flow rate of 1.0 ml/min. The linear regression equation of ellagic acid is： y=2.9e＋0.6x＋4.4e＋5 （FF=9 999）. Ac- cording to the standard addition recovery test, the average recovery rate of ellagic acid is 98.20%, and RSD is 0.60%. Under above optimized chromatographic condi- tions, ellagic acid can be well separated from other interfering components in pomegranate peels, with shorter peak time and ideal effect, which is convenient for the detection in production practices. [Conclusion] This study laid the foundation for detecting ellagic acid in pomegranate peels using HPLC method.

让第一线的教师“参政”对优秀教材评头论足

国家教委十分重视教材建设,决定从今年起每四年对高校优秀教材评奖一次,并颁发了评奖试行条例、试行办法,这确是教育界的一件大事、喜事。教材评选工作是件新事物。需要有个好的开始,除各院校申报,各地区、各部委评出或推荐后由国家教委组织的评委会(专家组成)遴选评定等一系列有组织的按部就班的程序外,可否再把听取意见的面扩大点,诸如公告初评结果,让众多的在第一线的执教者也参予意见等等。

是德科技推出业界首款5G综合测试软件,助力研发工程师设计和评测5G候选波形

新闻要点： 简化宽带发射、接收、收发测试系统搭建过程 促进从射频到毫米波测量系统的复杂校准,创建基于任务的测试设置指南,覆盖从信号生成到信号测量整个过程 生成和分析5G候选波形,以确保精确和可重复的测量。

美——我的十二个愿望

引子寻觅乐律与自然的同步追求乐情与理智的平衡宇宙是和谐、稳定而平衡的存在,也是矛盾、竞争而永恒运动着的存在。如果说,美的音乐最初来源于对宇宙大自然的一种模拟,它的本质也是通过对立因素的矛盾运动而达到和谐、稳定和平衡的。有了这种稳定、音乐才能有序地进行。音乐艺术是以一种特殊形式——在与时间同步的乐音流动中表现出人与人之间生活的真情。

A Note of the Uniqueness Criterion for Single Birth Processes

This paper is devoted to studying the si ngle birth processes. The uniqueness criterion for the processes is presented.

爱情与现代化:北京的一项调查报告

中國社會正在經歷着一個現代化過程。儘管人們對這一過程的性質看法各異——有的說,是從封建社會過渡到具有社會主義性質的社會;有的說,是從傳統社會向現代社會的過渡——但沒有人否認這一變化本身。這為檢驗浪漫愛情與現代化過程之間關係的理論,提供了一個絕好的機會。這一理論的要點是,隨着現代化過程的推進,婚姻將會發生變化——從以維持生活基本需要為主到以浪漫愛情為主。

Initial Alignment Technique for SINS of Vehicles in the Moving State

An initial alignment technique for the strapdown inertial navigation system (SINS) of vehicles in the moving state is researched. By selecting an odometer as the system’s external sensor, the mathematical model for the alignment in the moving state is established and the observability of the system is analyzed. The results show that the SINS can successfully achieve the precision alignment in 10 min when the vehicle is moving toward the prearranged place after its staying for several seconds to perform the coarse alignment. The precision of alignment can also be improved in the moving state compared with that in the static state.

爱情急诊

爱情中的无助,婚姻中的迷茫,《女人街》爱情急诊是你的知心朋友……本栏目特约主持:苇虹,时尚、情感编辑MAIL:wwbb2004@sina．com BLOG:weihong．blog．e23．cn Q他为何不想跟我结婚我和男友认识8年了,谈了5年的恋爱,结婚该是很自然的事吧。可他却说不想结婚!现在离婚期还有两个月了,现在我们房子也没装修,婚纱照也没拍,总之一切该准备的都没准备,这些事情都是我提出来的,可他一直说不用急。

浙二打造全国首个全数据互联互通网络医院

日前,浙二国际网络医学中心暨广济网络医院(一期)项目启动。得益于互联网技术,如今我们可以不必再为一张片子奔波:把检查单、化验结果、CT片拍个照上传到网上,就可以找到专家咨询治疗方案。但是,在业内人士看来,这样的'人工数据上传'+网络诊疗,不是真正意义上的网络医院。'对于疾病诊治来说,及时有效的医院影像数据、检验检查报告、病历资料等等完整的信息.

IC Implementation of a Programmable CMOS Voltage Reference

A new approach for the design and implementation of a programmable voltage reference based on an improved current mode bandgap voltage reference is presented. The circuit is simulated and fabricated with Chartered 0. 35μm mixed-signal technology. Measurements demonstrate that the temperature coefficient is ± 36. 3ppm/℃ from 0 to 100℃ when the VID inputs are 11110.As the supply voltage is varied from 2.7 to 5V, the voltage reference varies by about 5mV. The maximum glitch of the transient response is about 20mV at 125kHz. Depending on the state of the five VID inputs,an output voltage between 1.1 and 1.85V is programmed in increments of 25mV.

Analytical Solitary Wave Solutions to a (3+1)-Dimensional Gross—Pitaevskii Equation with Variable Coefficients

A(3+1)-dimensional Gross-Pitaevskii(GP)equation with time variable coefficients is considered,andis transformed into a standard nonlinear Schr(o|¨)dinger(NLS)equation.Exact solutions of the(3+1)D GP equationare constructed via those of the NLS equation.By applying specific time-modulated nonlinearities,dispersions,andpotentials,the dynamics of the solutions can be controlled.Solitary and periodic wave solutions with snaking andbreathing behavior are reported.

Pure quasi-P wave equation and numerical solution in 3D TTI media

Based on the pure quasi-P wave equation in transverse isotropic media with a vertical symmetry axis （VTI media）, a quasi-P wave equation is obtained in transverse isotropic media with a tilted symmetry axis （TTI media）. This is achieved using projection transformation, which rotates the direction vector in the coordinate system of observation toward the direction vector for the coordinate system in which the z-component is parallel to the symmetry axis of the TTI media. The equation has a simple form, is easily calculated, is not influenced by the pseudo-shear wave, and can be calculated reliably when δ is greater than ε. The finite difference method is used to solve the equation. In addition, a perfectly matched layer （PML） absorbing boundary condition is obtained for the equation. Theoretical analysis and numerical simulation results with forward modeling prove that the equation can accurately simulate a quasi-P wave in TTI medium.

0.18μm CMOS programmable frequency divider design for DVB-T

The implementation of a programmable frequency divider, which is one of the components of the phase-locked loop （PLL） frequency synthesizer for digital video broadcastingterrestrial （DVB-T） and other modem communication systems, is presented. By cooperating with a dual-modulus prescaler, this divider can realize an integer frequency division from 926 to 1 387. Besides the traditional standard cell design flow, such as logic synthesis, placement and routing, the interactions between front-end and back-end are also considered to optimize the design flow under deep submicron technology. By back-annotating the back-end information to front-end design, a custom wire-load model is created which is more practical compared with the default model. This divider has been fabricated in TSMC 0. 18μm CMOS technology using Artisan standard cell library. The chip area is 675 μm × 475 μm and the power consumption is about 2 mW under a 1.8 V power supply. Measurement results show that it works correctly and can realize a frequency division with high precision.

Global Well-posedness of the Generalized Long-short Wave Equations

In the present paper, we investigate the well-posedness of the global solutionfor the Cauchy problem of generalized long-short wave equations. Applying Kato＇s methodfor abstract quasi-linear evolution equations and a priori estimates of solution,we get theexistence of globally smooth solution.

Recent results of laparoscopic surgery in inflammatory bowel disease

Inflammatory bowel diseases are an ideal indication for the laparoscopic surgical approach as they are basically benign diseases not requiring lymphadenectomy and extended mesenteric excision;well-established surgical procedures are available for the conventional approach.Inflammatory alterations and fragility of the bowel and mesentery,however,may demand a high level of laparoscopic experience.A broad spectrum of operations from the rather easy enterostomy formation for anal Crohn’s disease(CD)to restorative proctocolectomies for ulcerative colitis(UC)may be managed laparoscopically.The current evidence base for the use of laparoscopic techniques in the surgical therapy of inflammatory bowel diseases is presented.CD limited to the terminal ileum has become a common indication for laparoscopic surgical therapy.In severe anal CD, laparoscopic stoma formation is a standard procedure with low morbidity and short operative time.Studies comparing conventional and laparoscopic bowel resections,have found shorter times to first postoperative bowel movements and shorter hospital stays as well as lower complication rates in favour of the laparoscopic approach.Even complicated cases with previous surgery,abscess formation and enteric fistulas may be op-erated on laparoscopically with a low morbidity.In UC, restorative proctocolectomy is the standard procedure in elective surgery.The demanding laparoscopic approach is increasingly used,however,mainly in major centers; its feasibility has been proven in various studies.An increased body mass index and acute inflammation of the bowel may be relative contraindications.Short and longterm outcomes like quality of life seem to be equivalent for open and laparoscopic surgery.Multiple studies have proven that the laparoscopic approach to CD and UC is a safe and successful alternative for selected patients. The appropriate selection criteria are still under investigation.Technical considerations are playing an important role for the complexity of both diseases.

iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability

Here, we provide data suggesting that the absence of silencing of the ectopic reprogramming factors used to reprogram somatic cells to induced pluripotent stem cells （iPSCs） may predispose iPSCs to genomic instability. We encourage stem cell scientists to undertake an extensive characterization and standardization of much larger cohorts of iPSC lines in order to set up rigorous criteria to define safe and stable bonafide iPSCs.

Inspection Methods and Quality Grading Standards for Codonopsis pilosula Seeds

[Objective] This study aimed to investigate the inspection methods and quality grading standards for Codonopsis pilosula seeds. [Method] A total of 27 shares of C. pilosula seeds were collected and surveyed from six counties in Shanxi, Gansu and Shaanxi provinces. The inspection methods of various indicators, such as purity, 1 000-grain weight, germination rate, vitality and moisture content, were investigated in accordance with Rules for Agricultural Seed Testing （GB/T 3543.1-7, 1995）, to develop the appropriate quality inspection method for C. pilosula seeds. Based on the developed inspection method and procedures, the quality of 27 shares of C. pilosula seed samples from different regions was inspected, thus es- tablishing quality grading standards for C. pilosula seeds with K-center clustering method. [Result] C. pilosula seeds are suitable to be cultivated in cool regions. The optimal germination temperature was 25 ~C; the optimal germination bed was gauze bed; the optimal staining conditions were： staining temperature 40 ~, TTC concen- tration 0.5%, staining time 4 h. On the basis of cluster analysis, the quality of C. pilosula seeds could be divided into three grades according to five indicators, includ- ing the purity, 1 000-grain weight, moisture content, vitality, and germination rate. Specifically, vitality and germination rate were important factors of grading standards due to the significant differences, followed by purity, 1 000-grain weight and mois- ture content. [Conclusion] This study provided an important basis for standardized cultivation and industrial development of C. pilosula.

Treatment of advanced rectal cancer after renal transplantation

Renal transplantation is a standard procedure for endstage renal disease today. Due to immunosuppressive drugs and increasing survival time after renal transplantation, patients with transplanted kidneys carry an increased risk of developing malignant tumors. In this case report, 3 patients with advanced rectal cancer after renal transplantation for renal failure were treated with anterior resection or abdominoperineal resection plus total mesorectal excision, followed by adjuvant chemotherapy. One patient eventually died of metastasized cancer 31 mo after therapy, although his organ grafts functioned well until his death. The other 2 patients were well during the 8 and 21 mo followup periods after rectal resection. We therefore strongly argue that patients with advanced rectal cancer should receive standard oncology treatment, including operation and adjuvant treatment after renal transplantation. Colorectal cancer screening in such patients appears justified.

An Oscillation Criterion for Second Order Superlinear Differential Equations

A new criterion is established for the oscillation of second order superlinear ordinary differential equations of the formx″(t) + p(t)x′(t) + q(t)｜x(t)｜αsgnx(t) = 0, t ≥ t0,where α>1,p and q are continuous functions on[t0,∞). This criterion extends and unifies some of the results obtained in [1]- [5].

Study on control of rock fragmentation at limestone quarry

The size distribution of a muck pile depends not on only the blasting standard but also on the mechanical properties,joint system,and crack density of the rock mass. As,the cracks in the rock masses are especially heavily developed at the limestone quar- ries in Japan,they,along with the joints,have a large impact on the effects of blasting, such as the size of the muck pile.Therefore,if the joint system and/or crack density in a rock mass can be determined and quantitatively evaluated,the blasting operation can be conducted more effectively,efficiently and safely.However,guidelines for designing ap- propriate blasting standards based on the rock mass conditions have not yet been scien- tifically developed.Therefore,blasting tests were conducted on different mines and faces, under different geological conditions and blasting standards,in order to determine the im- pacts of each factor on the effects of blasting.Summarized the results of a series of blast- ing tests and described the impacts of geological conditions on the size of the muck pile produced by blast.