Objective To probe into the impacts on the expression of vascular endothelial growth factor （VEGF） in ischemic brain tissue treated with cluster puncture on scalp acupoints in rats, Methods 128 rats were randomized ...Objective To probe into the impacts on the expression of vascular endothelial growth factor （VEGF） in ischemic brain tissue treated with cluster puncture on scalp acupoints in rats, Methods 128 rats were randomized into pseudo-operation group, model group, scalp-needling group and cluster-needling group, In scalp-needling group, penetration method was used on the focal side from Bǎihuì （百会 GV20） to Qǔbīn （曲鬓 GB7）, and in cluster-needling group, penetration method was used on both sides from GV20 to GB7, and a common needling on GV 20. Needles were punctured 2 mm in depth, constantly rotated for 10min, retained for 2 h. Immunohistrochemical method was applied to determine VEGF expression and microvessel density （MVD）. Results With the intervention of cluster puncture on scalp acupoints, VEGF： expressions on every time-spot after ischemia were enhanced apparently, superior to those in scalp-needling group. On the three time-spots of the 7^th, 14^th and 21^st days, MVD was increased after cluster puncture on scale acupoints, superior to those in scalp-needling group. Conclusion Cluster puncture on scalp acupoints up-regulated VEGF expression and promoted regeneration of microvessel.展开更多
Objective To observe the therapeutic effect of electro acupuncture at QIǖXǖ（丘墟GB40） for treating migraine and provide clinical study for Acupoints Dictionary of People＇s Republic of China. Methods Multi-center ...Objective To observe the therapeutic effect of electro acupuncture at QIǖXǖ（丘墟GB40） for treating migraine and provide clinical study for Acupoints Dictionary of People＇s Republic of China. Methods Multi-center （3 First-Class hospitals） study was adopted, and the involved 3 hospitals did clinical observation according to the requirements of the project. The methods are as follows. All cases were randomized into treatment group and control group according to their sequence. QIǖXǖ（丘墟GB40） was selected in treatment group, while Tiānshū （天枢 ST25） was selected in control group. Both groups were performed electro acupuncture, and syndromes indexes of migraine and 5-HT were observed before and after treatment. All data were analyzed by statistic software SPSS11.5. Results There was significant difference of VAS margin between two groups in each center and the combined center （u= -3. 362, P=0. 001 ）. There was significant difference of therapeutic effect of 4-week treatment between two groups in each clinical center and the combined center. The therapeutic effect of 3-month treatment between two groups in No. 1 and No. 3 hospitals, showed significant difference, the treatment group was better; while that of No. 2 hospital had no obvious difference. The therapeutic effect of 6-month treatment between two groups in each center and the combined center had significant difference, the treatment group was better. Conclusion The therapy of electro acupuncture at QIǖXǖ（丘墟GB40） is effective for migraine.展开更多
Objective To probe into the function mechanism of penetration therapy with head electrical acupuncture on Parkinson＇s disease. Methods Microinjection of 6-hydroxydopamin （6-OHDA） on the left cor- pus striatum was a...Objective To probe into the function mechanism of penetration therapy with head electrical acupuncture on Parkinson＇s disease. Methods Microinjection of 6-hydroxydopamin （6-OHDA） on the left cor- pus striatum was adopted to prepare rotation model of Parkinson^s disease in rat. Penetration therapy with head electrical acupuncture was administered in treatment. Normal group, sham-operation group, model group and penetration therapy group were set up. （1）lmmunohistochemical （IHC） method was used to test the morphology and count of positive cell of tyrosine hydroxylase （TH）. （2）RT-PCR technology was used to detect the expression of nestin mRNA of neural stem cell （NSC）. Results （1）Compared with model group, in pene- tration therapy group, the expressions of TH-positive neurons in immune response were increased in areal density （AD）, numerical density （ND） and integrating optic density （P〈0.05）. （2）Compared with model group, in penetration therapy group, the expression of nestin mRNA was increased （P〈0. 05）. Conclusion Penetration therapy with head electrical acupuncture promotes the proliferation of endogenous neural stem cells in substantia nigra of rat model of Parkinson＇s disease.展开更多
Objective To probe methods and therapeutic effects of Head Acupuncture on ischemic stroke. Methods One hundred and twelve cases were randomly divided into observation group (head acupuncture group) and control group (...Objective To probe methods and therapeutic effects of Head Acupuncture on ischemic stroke. Methods One hundred and twelve cases were randomly divided into observation group (head acupuncture group) and control group (body acupuncture group). After treatment of 28 days, changes of linguistic function and paralysis level of limbs before and after treatment were investigated. Results The total effective rate was 96.6% in the observation group and 90.7%, in the control group, with a significant difference between the two groups (P<0.05). Conclusion The electroacupuncture head point-through-point by penetrating two point therapy is one of effective methods for ischemic stroke.展开更多
In studying the syndrome of yang-hyperactivity, we found that most migraine patients were with hyperactivity of the liver-yang, stagnation of the liver-qiand blood stasis, and stagnation of the liverqi and deficiency ...In studying the syndrome of yang-hyperactivity, we found that most migraine patients were with hyperactivity of the liver-yang, stagnation of the liver-qiand blood stasis, and stagnation of the liverqi and deficiency of the spleen. To evaluate the needling effects on migraine and to approach its mechanism, we have launched a study in 207 cases since 1997. The results were satisfactory and reported as follows.展开更多
In the present paper, the authors in troduce Professor YAN Li’s experie nce on clinical application of elongated needle for the treatment of gastralgia, migraine and hysteria by acupuncture of Zhongwan (中脘 CV 12). ...In the present paper, the authors in troduce Professor YAN Li’s experie nce on clinical application of elongated needle for the treatment of gastralgia, migraine and hysteria by acupuncture of Zhongwan (中脘 CV 12). In addition, the y also introduce its operation methods and some points for attention. During ope ration of the elongated needle, the operator should manipulate it gently, avoidi ng rude insertion and rash withdrawal; rather, utilize the elasticity of the steel wire to press the needle downward slowly, and cause the favorable needlin g sensations to spread slowly downward to the affected region along with the mov ement of the needle body.展开更多
Objective: To observe the therapeutic effect of bloodletting plus point implantation of catgut in the treatment of 67 cases of vascular headache. Methods: A total of 107 cases of vascular headache patients were divide...Objective: To observe the therapeutic effect of bloodletting plus point implantation of catgut in the treatment of 67 cases of vascular headache. Methods: A total of 107 cases of vascular headache patients were divided into treatment group (n=67) and control group (n=40). Bilateral Taiyang (EX-HN 5) and Jiaosun (TE 20) were pricked with a needle to let a little blood out, once every 4 days. Bilateral Fengmen (BL 12) and Ganshu (BL 18) were used for embedding catgut, once every 16 days. Patients of control group were ordered to take Rotunding, Oryzanol and Nimodipine, 3 times daily. Results: After 16 days’ treatment, of the 67 cases in treatment group, 26 were cured, 37 responded with improvement in their symptoms and 4 failed; while of the 40 cases in control group, 10 were cured, 19 responded with improvement in their symptoms and 11 failed. The total effective rate of treatment group was significantly superior to that of control group (P<0.01). In addition, the time of headache disappearance of treatment group was strikingly shorter than that of control group; while the duration of sleep of treatment group was strikingly longer than that of control group (P<0.01). Conclusion: The therapeutic effect of acupoint bloodletting plus acupoint embedding of catgut is superior to that of Western medicine in the treatment of vascular headache.展开更多
Objective: To explore a new effective approach for treatment of the local irritable symptoms and signs resulted from myoporthosis operation. Methods: 263 cases of radial keratotomy outpatients were divided into contro...Objective: To explore a new effective approach for treatment of the local irritable symptoms and signs resulted from myoporthosis operation. Methods: 263 cases of radial keratotomy outpatients were divided into control group (n=49, 90 eyes) and treatment group (n=214, 412 eyes). Patients of control group were treated with 0.5% Chloramphenicol eye drops, 3 times daily, 1-2 drops/time, and with 0.5% Erythromycine eye ointment every night. In treatment group, patients were treated with acupoint and hand reflection area digital pressing method except with the same eye drops and eye ointment. Body acupoints used were Cuanzhu (BL 2), Yuyao (EX HN 4), Sizhukong (TE 23), Sibai (ST 2) and Taiyang (EX HN 5). The hand reflex areas used were Eye Area, Liver Area, Kidney Area, Spleen Area, Heart Area and Lung Area. Five days constituted a therapeutic course. Results: Following 3 courses (15 days) of treatment, the markedly effective rate and total effective rate of treatment group and control group were 74.51% and 38.89%, 94.17% and 66.67% respectively. There was a significant difference between two groups in the total effective rate (P<0.05), showing the therapeutic effect of treatment group being better than that of control group. Conclusion: Acupoint digital pressing is rather effective in treatment of myoporthosis post operation irritable symptoms and signs.展开更多
Objective To observe therapeutic effects of scalp acupuncture at close acupoints combined with rehabilitation training on balance functions of children with cerebral palsy （CP）. Methods Sixty children with CP were r...Objective To observe therapeutic effects of scalp acupuncture at close acupoints combined with rehabilitation training on balance functions of children with cerebral palsy （CP）. Methods Sixty children with CP were randomly divided into a scalp acupuncture combined with rehabilitation training group （group SA＋RT） and a rehabilitation training group （group RT） with 30 cases in each group. Conventional rehabilitation therapy and balance training were applied in group RT, and scalp acupuncture at close acupoints in the parietal region and sub-occipital region was added besides rehabilitation training in group SA＋RT. Balance functions were evaluated by using Berg rating scale, and abilities of daily living were estimated by using rating scale for activities of daily living （ADL）. Results After treatment, both Berg scores for balance and ADL scores were significantly improved in both groups （all P0.05）, and the improvement in group SA＋RT was more obvious than that in group RT （ both P0.05）. Conclusion Combination of scalp acupuncture at close acupoints with rehabilitation training is superior to simple rehabilitation training in improving balance functions and activities of daily living in children with cerebral palsy.展开更多
文摘Objective To probe into the impacts on the expression of vascular endothelial growth factor （VEGF） in ischemic brain tissue treated with cluster puncture on scalp acupoints in rats, Methods 128 rats were randomized into pseudo-operation group, model group, scalp-needling group and cluster-needling group, In scalp-needling group, penetration method was used on the focal side from Bǎihuì （百会 GV20） to Qǔbīn （曲鬓 GB7）, and in cluster-needling group, penetration method was used on both sides from GV20 to GB7, and a common needling on GV 20. Needles were punctured 2 mm in depth, constantly rotated for 10min, retained for 2 h. Immunohistrochemical method was applied to determine VEGF expression and microvessel density （MVD）. Results With the intervention of cluster puncture on scalp acupoints, VEGF： expressions on every time-spot after ischemia were enhanced apparently, superior to those in scalp-needling group. On the three time-spots of the 7^th, 14^th and 21^st days, MVD was increased after cluster puncture on scale acupoints, superior to those in scalp-needling group. Conclusion Cluster puncture on scalp acupoints up-regulated VEGF expression and promoted regeneration of microvessel.
文摘Objective To observe the therapeutic effect of electro acupuncture at QIǖXǖ（丘墟GB40） for treating migraine and provide clinical study for Acupoints Dictionary of People＇s Republic of China. Methods Multi-center （3 First-Class hospitals） study was adopted, and the involved 3 hospitals did clinical observation according to the requirements of the project. The methods are as follows. All cases were randomized into treatment group and control group according to their sequence. QIǖXǖ（丘墟GB40） was selected in treatment group, while Tiānshū （天枢 ST25） was selected in control group. Both groups were performed electro acupuncture, and syndromes indexes of migraine and 5-HT were observed before and after treatment. All data were analyzed by statistic software SPSS11.5. Results There was significant difference of VAS margin between two groups in each center and the combined center （u= -3. 362, P=0. 001 ）. There was significant difference of therapeutic effect of 4-week treatment between two groups in each clinical center and the combined center. The therapeutic effect of 3-month treatment between two groups in No. 1 and No. 3 hospitals, showed significant difference, the treatment group was better; while that of No. 2 hospital had no obvious difference. The therapeutic effect of 6-month treatment between two groups in each center and the combined center had significant difference, the treatment group was better. Conclusion The therapy of electro acupuncture at QIǖXǖ（丘墟GB40） is effective for migraine.
基金the Excellent Discipline Leadership Fund Project of Harbin Science-Technology Administration :2006RFXYS044
文摘Objective To probe into the function mechanism of penetration therapy with head electrical acupuncture on Parkinson＇s disease. Methods Microinjection of 6-hydroxydopamin （6-OHDA） on the left cor- pus striatum was adopted to prepare rotation model of Parkinson^s disease in rat. Penetration therapy with head electrical acupuncture was administered in treatment. Normal group, sham-operation group, model group and penetration therapy group were set up. （1）lmmunohistochemical （IHC） method was used to test the morphology and count of positive cell of tyrosine hydroxylase （TH）. （2）RT-PCR technology was used to detect the expression of nestin mRNA of neural stem cell （NSC）. Results （1）Compared with model group, in pene- tration therapy group, the expressions of TH-positive neurons in immune response were increased in areal density （AD）, numerical density （ND） and integrating optic density （P〈0.05）. （2）Compared with model group, in penetration therapy group, the expression of nestin mRNA was increased （P〈0. 05）. Conclusion Penetration therapy with head electrical acupuncture promotes the proliferation of endogenous neural stem cells in substantia nigra of rat model of Parkinson＇s disease.
基金This Study is one of the preeminent Researches in Chinese Medicine and Pharmacology supported by Jiangxi Health Care Administration. Code :2006A43~~
文摘Objective To probe methods and therapeutic effects of Head Acupuncture on ischemic stroke. Methods One hundred and twelve cases were randomly divided into observation group (head acupuncture group) and control group (body acupuncture group). After treatment of 28 days, changes of linguistic function and paralysis level of limbs before and after treatment were investigated. Results The total effective rate was 96.6% in the observation group and 90.7%, in the control group, with a significant difference between the two groups (P<0.05). Conclusion The electroacupuncture head point-through-point by penetrating two point therapy is one of effective methods for ischemic stroke.
文摘In studying the syndrome of yang-hyperactivity, we found that most migraine patients were with hyperactivity of the liver-yang, stagnation of the liver-qiand blood stasis, and stagnation of the liverqi and deficiency of the spleen. To evaluate the needling effects on migraine and to approach its mechanism, we have launched a study in 207 cases since 1997. The results were satisfactory and reported as follows.
文摘In the present paper, the authors in troduce Professor YAN Li’s experie nce on clinical application of elongated needle for the treatment of gastralgia, migraine and hysteria by acupuncture of Zhongwan (中脘 CV 12). In addition, the y also introduce its operation methods and some points for attention. During ope ration of the elongated needle, the operator should manipulate it gently, avoidi ng rude insertion and rash withdrawal; rather, utilize the elasticity of the steel wire to press the needle downward slowly, and cause the favorable needlin g sensations to spread slowly downward to the affected region along with the mov ement of the needle body.
文摘Objective: To observe the therapeutic effect of bloodletting plus point implantation of catgut in the treatment of 67 cases of vascular headache. Methods: A total of 107 cases of vascular headache patients were divided into treatment group (n=67) and control group (n=40). Bilateral Taiyang (EX-HN 5) and Jiaosun (TE 20) were pricked with a needle to let a little blood out, once every 4 days. Bilateral Fengmen (BL 12) and Ganshu (BL 18) were used for embedding catgut, once every 16 days. Patients of control group were ordered to take Rotunding, Oryzanol and Nimodipine, 3 times daily. Results: After 16 days’ treatment, of the 67 cases in treatment group, 26 were cured, 37 responded with improvement in their symptoms and 4 failed; while of the 40 cases in control group, 10 were cured, 19 responded with improvement in their symptoms and 11 failed. The total effective rate of treatment group was significantly superior to that of control group (P<0.01). In addition, the time of headache disappearance of treatment group was strikingly shorter than that of control group; while the duration of sleep of treatment group was strikingly longer than that of control group (P<0.01). Conclusion: The therapeutic effect of acupoint bloodletting plus acupoint embedding of catgut is superior to that of Western medicine in the treatment of vascular headache.
文摘Objective: To explore a new effective approach for treatment of the local irritable symptoms and signs resulted from myoporthosis operation. Methods: 263 cases of radial keratotomy outpatients were divided into control group (n=49, 90 eyes) and treatment group (n=214, 412 eyes). Patients of control group were treated with 0.5% Chloramphenicol eye drops, 3 times daily, 1-2 drops/time, and with 0.5% Erythromycine eye ointment every night. In treatment group, patients were treated with acupoint and hand reflection area digital pressing method except with the same eye drops and eye ointment. Body acupoints used were Cuanzhu (BL 2), Yuyao (EX HN 4), Sizhukong (TE 23), Sibai (ST 2) and Taiyang (EX HN 5). The hand reflex areas used were Eye Area, Liver Area, Kidney Area, Spleen Area, Heart Area and Lung Area. Five days constituted a therapeutic course. Results: Following 3 courses (15 days) of treatment, the markedly effective rate and total effective rate of treatment group and control group were 74.51% and 38.89%, 94.17% and 66.67% respectively. There was a significant difference between two groups in the total effective rate (P<0.05), showing the therapeutic effect of treatment group being better than that of control group. Conclusion: Acupoint digital pressing is rather effective in treatment of myoporthosis post operation irritable symptoms and signs.
文摘Objective To observe therapeutic effects of scalp acupuncture at close acupoints combined with rehabilitation training on balance functions of children with cerebral palsy （CP）. Methods Sixty children with CP were randomly divided into a scalp acupuncture combined with rehabilitation training group （group SA＋RT） and a rehabilitation training group （group RT） with 30 cases in each group. Conventional rehabilitation therapy and balance training were applied in group RT, and scalp acupuncture at close acupoints in the parietal region and sub-occipital region was added besides rehabilitation training in group SA＋RT. Balance functions were evaluated by using Berg rating scale, and abilities of daily living were estimated by using rating scale for activities of daily living （ADL）. Results After treatment, both Berg scores for balance and ADL scores were significantly improved in both groups （all P0.05）, and the improvement in group SA＋RT was more obvious than that in group RT （ both P0.05）. Conclusion Combination of scalp acupuncture at close acupoints with rehabilitation training is superior to simple rehabilitation training in improving balance functions and activities of daily living in children with cerebral palsy.
