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针灸预处理对阿尔茨海默病大鼠学习记忆行为的影响 被引量:7
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作者 周华 孙国杰 +5 位作者 孔立红 曾晓玲 杜艳军 王述菊 陈邦国 沈峰 《湖北中医学院学报》 2011年第1期3-5,共3页
目的观察针灸预处理对AD大鼠学习记忆行为的影响。方法大鼠随机分为正常组、假手术组、模型组、预艾灸组、预电针组、预电针加灸组,在大鼠双侧海马区注射Aβ25-35,建立AD大鼠模型,通过定位航行实验和空间搜索实验检测针灸预处理对记忆... 目的观察针灸预处理对AD大鼠学习记忆行为的影响。方法大鼠随机分为正常组、假手术组、模型组、预艾灸组、预电针组、预电针加灸组,在大鼠双侧海马区注射Aβ25-35,建立AD大鼠模型,通过定位航行实验和空间搜索实验检测针灸预处理对记忆损害的预防和治疗作用。结果模型组大鼠学习记忆能力有明显损害,其平均潜伏期、经过中心区域的比例、平均游过的路径距离与正常组和假手术组有显著差异(P<0.01),而预电针和预艾灸对其有明显的预防和改善作用,其中以预电针加灸的疗效最好。结论针灸预处理对AD大鼠学习记忆行为具有保护作用。 展开更多
关键词 针灸预处理 AD 定位航行实验 空间搜索实验
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Genetic algorithm for short-term scheduling of make-and-pack batch production process 被引量:1
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作者 Wuthichai Wongthatsanekorn Busaba Phruksaphanrat 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2015年第9期1475-1483,共9页
This paper considers a scheduling problem in industrial make-and-pack batch production process. This process equips with sequence-dependent changeover time, multipurpose storage units with limited capacity, storage ti... This paper considers a scheduling problem in industrial make-and-pack batch production process. This process equips with sequence-dependent changeover time, multipurpose storage units with limited capacity, storage time, batch splitting, partial equipment connectivity and transfer time. The objective is to make a production plan to satisfy all constraints while meeting demand requirement of packed products from various product families. This problem is NP-hard and the problem size is exponentially large for a realistic-sized problem. Therefore,we propose a genetic algorithm to handle this problem. Solutions to the problems are represented by chromosomes of product family sequences. These sequences are decoded to assign the resource for producing packed products according to forward assignment strategy and resource selection rules. These techniques greatly reduce unnecessary search space and improve search speed. In addition, design of experiment is carefully utilized to determine appropriate parameter settings. Ant colony optimization and Tabu search are also implemented for comparison. At the end of each heuristics, local search is applied for the packed product sequence to improve makespan. In an experimental analysis, all heuristics show the capability to solve large instances within reasonable computational time. In all problem instances, genetic algorithm averagely outperforms ant colony optimization and Tabu search with slightly longer computational time. 展开更多
关键词 Genetic algorithm Ant colony optimization Tabu search Batch scheduling Make-and-pack production Forward assignment strategy
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