Basal cell carcinoma (BCC) is the most common tumor in humans and is defined as a slow-growing, locally invasive, epithelial skin tumor which rarely metast asizes.The first line treatment is surgical excisionwith hist...Basal cell carcinoma (BCC) is the most common tumor in humans and is defined as a slow-growing, locally invasive, epithelial skin tumor which rarely metast asizes.The first line treatment is surgical excisionwith histologic examination of the tumormargins, but numerous alternative therapies are available. A 75- ya r old patient with the most destructive form of BCC, ulcusterebrans, involving the scalp and invading the frontal bone. We discuss the problems and therapeu tic limitations for this unusual BCC variant.展开更多
目的:观察本法治疗消化性溃疡急性穿孔并发脓毒症的效果.方法:在常规手术和抗生素治疗基础上,给予中药通腑泻热方治疗本病23例,与常规治疗的 21例作随机对照观察.结果:与对照组比较,治疗组并发症发生率降低(肠梗阻5/23 vs 11/21,P&l...目的:观察本法治疗消化性溃疡急性穿孔并发脓毒症的效果.方法:在常规手术和抗生素治疗基础上,给予中药通腑泻热方治疗本病23例,与常规治疗的 21例作随机对照观察.结果:与对照组比较,治疗组并发症发生率降低(肠梗阻5/23 vs 11/21,P<0.05;MODS: 2/23 vs 7/21,P<0.05),死亡率呈下降趋势,治疗后血浆内毒素(8.7±3.2 kEU/L vs 16.8± 4.5 kEU/L,P<0.01),TNF-α(23.3±8.6 ng/L vs 30.7±8.7 ng/L,P<0.01),IL-6(30.4±13.6 ng/ L vs 51.4±16.2 ng/L,P<0.01),IL-8(20.6± 9.4 ng/L vs 31.7±10.8 ng/L,P<0.01)均显著降低,IL-2(754.8±72.4 ng/L vs 600.8±65.8 ng.L, P<0.01)明显升高.结论:中药通腑泻热方能降低消化性溃疡急性穿孔并发脓毒症患者血中内毒素及促炎细胞因子水平,能提高与机体免疫功能直接相关的细胞因子,防治MODS,降低病死率.展开更多
文摘Basal cell carcinoma (BCC) is the most common tumor in humans and is defined as a slow-growing, locally invasive, epithelial skin tumor which rarely metast asizes.The first line treatment is surgical excisionwith histologic examination of the tumormargins, but numerous alternative therapies are available. A 75- ya r old patient with the most destructive form of BCC, ulcusterebrans, involving the scalp and invading the frontal bone. We discuss the problems and therapeu tic limitations for this unusual BCC variant.
文摘目的:观察本法治疗消化性溃疡急性穿孔并发脓毒症的效果.方法:在常规手术和抗生素治疗基础上,给予中药通腑泻热方治疗本病23例,与常规治疗的 21例作随机对照观察.结果:与对照组比较,治疗组并发症发生率降低(肠梗阻5/23 vs 11/21,P<0.05;MODS: 2/23 vs 7/21,P<0.05),死亡率呈下降趋势,治疗后血浆内毒素(8.7±3.2 kEU/L vs 16.8± 4.5 kEU/L,P<0.01),TNF-α(23.3±8.6 ng/L vs 30.7±8.7 ng/L,P<0.01),IL-6(30.4±13.6 ng/ L vs 51.4±16.2 ng/L,P<0.01),IL-8(20.6± 9.4 ng/L vs 31.7±10.8 ng/L,P<0.01)均显著降低,IL-2(754.8±72.4 ng/L vs 600.8±65.8 ng.L, P<0.01)明显升高.结论:中药通腑泻热方能降低消化性溃疡急性穿孔并发脓毒症患者血中内毒素及促炎细胞因子水平,能提高与机体免疫功能直接相关的细胞因子,防治MODS,降低病死率.