目的:研究短梗五加果多酚(Acanthopanax sessiliflorus fruit polyphenols,ASFP)对大鼠动脉粥样硬化(atherosclerosis,As)的预防作用,并探讨其作用机制。方法:40只雄性SD大鼠随机平均分成4组,每组10只。采用高脂饮食结合腹腔注射VD3的...目的:研究短梗五加果多酚(Acanthopanax sessiliflorus fruit polyphenols,ASFP)对大鼠动脉粥样硬化(atherosclerosis,As)的预防作用,并探讨其作用机制。方法:40只雄性SD大鼠随机平均分成4组,每组10只。采用高脂饮食结合腹腔注射VD3的方法建立As模型,不同剂量ASFP给药组自造模开始之日起分别灌胃150、75 mg/(kg·d)的ASFP,空白组和高脂饮食组大鼠灌胃等量生理盐水,各实验组连续处理12周后,检测大鼠血清生理生化水平并计算As指数;苏木素-伊红染色观察大鼠主动脉As病变情况;Western blot检测主动脉中黏附分子和丝裂原活化蛋白激酶(mitogen-activated protein kinase,MAPK)信号通路关键基因的蛋白表达水平。结果:与高脂饮食组相比,ASFP能显著降低大鼠血清中的血脂、黏附分子和炎症因子水平,减少主动脉中的脂质沉积,改善各层结构排列紊乱,显著降低主动脉中细胞间黏附分子-1、血管细胞黏附分子-1、磷酸化p38和磷酸化细胞外信号调节蛋白激酶1/2(phospho-extracellular signal regulated kinases 1/2,p-ERK1/2)的蛋白表达量。结论:ASFP具有预防As的作用,其作用可能与其降血脂和抑制p38 MAPK和ERK1/2 MAPK信号通路,进而抑制炎症因子的表达有关。展开更多
By using ZHANG Qiao＇s method for identifying fuzzy words （1998）, the present paper makes a statistic analysis of fuzzy words appearing in about 43,000 words of 6 academic research articles in management science. A ...By using ZHANG Qiao＇s method for identifying fuzzy words （1998）, the present paper makes a statistic analysis of fuzzy words appearing in about 43,000 words of 6 academic research articles in management science. A distribution curve of fuzzy words in management research articles is drawn in accordance with the structures of the articles, and it is proved to be reasonable for tile discourse function of each section. Furthermore, the fuzzy words are divided into three categories and eleven sub-categories, including Category Ⅰ-fuzzy words, Category Ⅱ-fuzzy words＋non-fuzzy part / non-fuzzy part＋fuzzy words, Category Ⅲ-approximators＋fuzzy words. Distribution of fuzzy words varies in different sections of research articles in management science, because of different communicative purposes or discourse functions. Introduction section and Conclusion section have a higher occurrence rate of fuzzy words than Abstract section and Methodology and Data section.展开更多
Fouty-eight species of rare and endanged plants in the Fenhe Source,belong to 21 families 37 genera.There were 1specie of national second-class protected plant and 3 species of national third-class plants;4 species of...Fouty-eight species of rare and endanged plants in the Fenhe Source,belong to 21 families 37 genera.There were 1specie of national second-class protected plant and 3 species of national third-class plants;4 species of first-class protected plants,6 species of second-class protected plants and 14 species of third-class protected plants in Shanxi Province.On the basis of analyzing the endanged reasons,related protection countemeasures were put forward in this article.展开更多
Discourse markers have been studied within the relevance theoretical framework in this paper. According to relevance theory, every act of ostensive communication communicates a presumption of its own optimal relevance...Discourse markers have been studied within the relevance theoretical framework in this paper. According to relevance theory, every act of ostensive communication communicates a presumption of its own optimal relevance. The communicator, who is aiming at optimal relevance, must direct the audience to a particular set of assumptions by using discourse markers. Whereas, from the audience＇s point of view, discourse markers can minimize his contextual assumptions in looking for relevance, thus the pragmatic inferential process will be much easier.展开更多
Cracking in concrete occurs from volumetric instability, mechanical loading, and/or environmental attack. Compared to conventional vibrated concrete, self-consolidating concrete often has a higher susceptibility to cr...Cracking in concrete occurs from volumetric instability, mechanical loading, and/or environmental attack. Compared to conventional vibrated concrete, self-consolidating concrete often has a higher susceptibility to crack due to different mixture design, material properties and construction practices. To obtain a better understanding of self-consolidating concrete cracking behaviors for designing and constructing crack-controlled structural elements, reported current research and practices are reviewed and analyzed in this paper. It has been believed that when well designed and welt constructed, high quality self- consolidating concrete can be successfully used in various structures with cracks properly controlled.展开更多
To implement structural hybrid simulation independent of the control system of any testing equipment in civil engineering, an external command control approach is put forward. Several setup technologies and the corres...To implement structural hybrid simulation independent of the control system of any testing equipment in civil engineering, an external command control approach is put forward. Several setup technologies and the corresponding API approaches are investigated to simultaneously combine numerical simulation with physical testing. Hybrid program technology is put forward and described in detail, using Visual C++ program to effectively and accurately control testing equipment and MATLAB program to implement numerical simulation with easy extension. The control program of testing equipment and numerical simulation program are integrated by calling MATLAB engine in Visual C++. A hybrid simulation about a full-scale six-story masonry structure is carried out. The testing results manifest that the external command control approach has the versatility because of simple hardware connection and control program independent on control software of testing equipment; powerful program function of Visual C++ and flexible program of MATLAB are integrated by hybrid program technology; hybrid simulation system provides a realistic and cost-effective testing platform that enables earthquake engineer researchers to accurately and efficiently capture the seismic performance of large or complex structures without having to carry out physical testing of the entire structure.展开更多
文摘目的:研究短梗五加果多酚(Acanthopanax sessiliflorus fruit polyphenols,ASFP)对大鼠动脉粥样硬化(atherosclerosis,As)的预防作用,并探讨其作用机制。方法:40只雄性SD大鼠随机平均分成4组,每组10只。采用高脂饮食结合腹腔注射VD3的方法建立As模型,不同剂量ASFP给药组自造模开始之日起分别灌胃150、75 mg/(kg·d)的ASFP,空白组和高脂饮食组大鼠灌胃等量生理盐水,各实验组连续处理12周后,检测大鼠血清生理生化水平并计算As指数;苏木素-伊红染色观察大鼠主动脉As病变情况;Western blot检测主动脉中黏附分子和丝裂原活化蛋白激酶(mitogen-activated protein kinase,MAPK)信号通路关键基因的蛋白表达水平。结果:与高脂饮食组相比,ASFP能显著降低大鼠血清中的血脂、黏附分子和炎症因子水平,减少主动脉中的脂质沉积,改善各层结构排列紊乱,显著降低主动脉中细胞间黏附分子-1、血管细胞黏附分子-1、磷酸化p38和磷酸化细胞外信号调节蛋白激酶1/2(phospho-extracellular signal regulated kinases 1/2,p-ERK1/2)的蛋白表达量。结论:ASFP具有预防As的作用,其作用可能与其降血脂和抑制p38 MAPK和ERK1/2 MAPK信号通路,进而抑制炎症因子的表达有关。
文摘By using ZHANG Qiao＇s method for identifying fuzzy words （1998）, the present paper makes a statistic analysis of fuzzy words appearing in about 43,000 words of 6 academic research articles in management science. A distribution curve of fuzzy words in management research articles is drawn in accordance with the structures of the articles, and it is proved to be reasonable for tile discourse function of each section. Furthermore, the fuzzy words are divided into three categories and eleven sub-categories, including Category Ⅰ-fuzzy words, Category Ⅱ-fuzzy words＋non-fuzzy part / non-fuzzy part＋fuzzy words, Category Ⅲ-approximators＋fuzzy words. Distribution of fuzzy words varies in different sections of research articles in management science, because of different communicative purposes or discourse functions. Introduction section and Conclusion section have a higher occurrence rate of fuzzy words than Abstract section and Methodology and Data section.
基金Supported by Shanxi Natural Science Foundation(2006011095)~~
文摘Fouty-eight species of rare and endanged plants in the Fenhe Source,belong to 21 families 37 genera.There were 1specie of national second-class protected plant and 3 species of national third-class plants;4 species of first-class protected plants,6 species of second-class protected plants and 14 species of third-class protected plants in Shanxi Province.On the basis of analyzing the endanged reasons,related protection countemeasures were put forward in this article.
文摘Discourse markers have been studied within the relevance theoretical framework in this paper. According to relevance theory, every act of ostensive communication communicates a presumption of its own optimal relevance. The communicator, who is aiming at optimal relevance, must direct the audience to a particular set of assumptions by using discourse markers. Whereas, from the audience＇s point of view, discourse markers can minimize his contextual assumptions in looking for relevance, thus the pragmatic inferential process will be much easier.
基金Funded by National Cooperative Highway Research Program(NCHRP) 18-16 in the US: Self-Consolidating Concrete for Cast-in-Place Bridge Components
文摘Cracking in concrete occurs from volumetric instability, mechanical loading, and/or environmental attack. Compared to conventional vibrated concrete, self-consolidating concrete often has a higher susceptibility to crack due to different mixture design, material properties and construction practices. To obtain a better understanding of self-consolidating concrete cracking behaviors for designing and constructing crack-controlled structural elements, reported current research and practices are reviewed and analyzed in this paper. It has been believed that when well designed and welt constructed, high quality self- consolidating concrete can be successfully used in various structures with cracks properly controlled.
基金Funded by National Natural Science Foundation of China under the Grant No.90715036Open Project of Jiangsu Key Laboratory of Structural Engineering (Grant No.ZD1004)Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
文摘To implement structural hybrid simulation independent of the control system of any testing equipment in civil engineering, an external command control approach is put forward. Several setup technologies and the corresponding API approaches are investigated to simultaneously combine numerical simulation with physical testing. Hybrid program technology is put forward and described in detail, using Visual C++ program to effectively and accurately control testing equipment and MATLAB program to implement numerical simulation with easy extension. The control program of testing equipment and numerical simulation program are integrated by calling MATLAB engine in Visual C++. A hybrid simulation about a full-scale six-story masonry structure is carried out. The testing results manifest that the external command control approach has the versatility because of simple hardware connection and control program independent on control software of testing equipment; powerful program function of Visual C++ and flexible program of MATLAB are integrated by hybrid program technology; hybrid simulation system provides a realistic and cost-effective testing platform that enables earthquake engineer researchers to accurately and efficiently capture the seismic performance of large or complex structures without having to carry out physical testing of the entire structure.
