胆汁肿瘤标志物检测对于胆管远端良恶性狭窄鉴别诊断的价值

目的探讨ERCP中胆汁肿瘤标志物的检测对于胆管远端良恶性狭窄鉴别诊断的价值。方法对经手术或病理学确诊的20例胆管远端恶性狭窄,30例胆管远端良性狭窄患者及13例非胆胰疾病志愿者在ERCP或PTC时提取胆汁,采用免疫放射分析法(IRMA)检测胆汁和血清的CA19-9,CEA,AFP含量,评价其诊断价值。结果当界定值为30000u/ml,胆汁肿瘤标志物CA19-9检测诊断胆管远端恶性狭窄的敏感性为85%,与血清学检测结果比较有差异。血清学联合胆汁中检测肿瘤标志物CA19-9可提高对胆管远端恶性狭窄的诊断的敏感性、特异性、准确性。结论 ERCP中胆汁肿瘤标志物检测可提高对胆管远端恶性狭窄的鉴别诊断。

记日本道端良秀长老的北京之行

在去年岁暮天寒之际,日本日中友好佛教协会理事长道端良秀长老在访问欧洲回国后不久,又于十二月二十六日来我国访问。八十高龄的道端长老是中国人民的老朋友。几年来为促进中日两国的友好事业和佛教文化的交流,作出了不懈的努力。他同赵朴初会长有着深厚诚挚的友谊。这次,他在佛协为他洗尘举行的宴会上说:“今天我看到赵朴初先生,好象回到自己家乡见到久别的亲兄弟一样。日中佛教界的友谊已经有一千多年的历史,我们应当继承和发扬这种友好的传统。

Telomerase Activity in Human Renal Cell Carcinoma with Reference to Clinicopathologic Features

Objective: To study the telomerase activity in human renal cell carcinoma and to evaluate the correlation with the clinicobiologic features of the neogrowth.Methods: The telomerase activity was studied by means of a modified telomeric repeat amplification protocol (TRAP) in 32 renal cell carcinoma tissues, 32 normal renal tissues and 32 paracancer tissues and its correlation with the clinicopathologic features of the tumor was evaluated.Results: Telomerase activity was strongly positive in 17, positive in 12 and negative in 3 cases of renal cell carcinoma tissues, the total positive rate being 91%. Telomerase activity was weakly positive (6%) in only 2 out of 32 samples of normal renal cortex tissues and positive in 6 paracancer tissues (19%), the difference was conspicuous (P<0.01).Conclusion: The positive rate of telomerase activity was significantly higher in renal cell carcinoma tissues and might serve as a prognostic marker for estimating the biologic characteristics of renal cell carcinoma.

Expression of telomerase gene and apoptosis related genes in benign and malignant breast lesion

Objective:To analyse the expression of telomerase and apoptosis related protein,and explore the possible mechanism of breast cancer development.Methods:Immunohistochemistry method(SP)was used to detect the expression of hTERT,p53 and bcl-2 in the tissues of 48 cases of human breast cancer and 42 cases of benign lesions in breast.Results: The positive rates of expression of hTERT,p53 and bcl-2 in breast cancer were 87.50%,56.25%and 54.17%,respectively. Compared with the groups of adjacent noncancerous and benign lesions,there was a significant difference among three types of tissues(P<0.05).The positive rates of expression of p53 and bcl-2 in the group with positive expression of hTERT were 64.28%and 61.90%,respectively,and their difference was significant compared with the negative group(P<0.05). Conclusion:There is a correlation between the activation of telomerases and p53 gene mutation in the development of breast cancer,and they are perhaps relation to the down regulation of bcl-2.

传印法师赴日参加“京都清凉寺释迦旃檀像渡日一千年纪念法会”

本刊讯应日本京都清凉寺住持鹈饲光顺长老的邀请,中国佛协理事传印法师于1986年11月6日至12日赴日参加“京都清凉寺释迦旃檀像渡日一千年纪念法会”,并进行友好访问。清凉寺的这尊释迦旃檀像,是由入宋日僧奝然于公元986年从中国携回日本的,后来一直供奉在清凉寺。现已被定为日本“国宝”。传印法师代表中国佛协向清凉寺赠送了礼品。

日中友好佛教协会第五次访华团来华访问

应中国佛教协会的邀请,日中友好佛教协会第五次友好访华团,在会长道端良秀长老率领下,于四月二十五日至五月八日,由赵朴初会长陪同,访问了北京、成都、重庆、武汉、上海等地,受到我国佛教界和各有关部门的热烈欢迎。四月二十五日,道端长老一行抵达北京时,中国佛教协会赵朴初会长亲自到机场迎接,当晚,设宴为远道而来的朋友们洗尘,国务院宗教事务局乔连升局长等出席了宴会。