目的观察有缺血性脑卒中病史的2型糖尿病(T2DM)患者视网膜血管直径变化,并分析其临床意义。方法T2DM患者480例,根据有无缺血性脑卒中病史分为缺血性脑卒中组73例、非缺血性脑卒中组407例,使用眼底照相机和半自动测量软件ARIA测量视网膜...目的观察有缺血性脑卒中病史的2型糖尿病(T2DM)患者视网膜血管直径变化,并分析其临床意义。方法T2DM患者480例,根据有无缺血性脑卒中病史分为缺血性脑卒中组73例、非缺血性脑卒中组407例,使用眼底照相机和半自动测量软件ARIA测量视网膜动脉和静脉直径,计算视网膜中央静脉等效值(CRVE)、视网膜中央动脉等效值(CRAE)、动静脉比值(AVR)。收集患者的年龄、体质量指数(BMI)、吸烟史、饮酒史、高血压病史、糖尿病视网膜病变(DR)病史、糖尿病肾病(DN)病史等一般资料。将研究对象分别按照CRVE、CRAE、AVR四分位数分为4组,作为等级变量纳入logistic回归分析模型进行趋势性检验,以缺血性脑卒中患病率为因变量,分析T2DM患者视网膜血管直径与缺血性脑卒中患病率的关系。按年龄、性别、糖尿病病程、有无DR病史、有无DN病史、有无高血压病史进行分层,通过在logistic回归模型中包含交叉积交互项来检验CRAE、AVR与每个分层变量之间的交互作用,分析T2DM患者不同分层人群中视网膜血管直径与缺血性脑卒中患病率变化趋势的稳健性。结果缺血性脑卒中组患者CRVE、AVR均低于非缺血性脑卒中组(P均<0.05)。与非缺血性脑卒中组相比,缺血性脑卒中组患者年龄更大,糖尿病病程更长,有高血压、DN、DR病史者更多,SBP、SCr、Cys-C水平更高,TC、LDL-C水平更低(P均<0.05)。T2DM患者缺血性脑卒中的患病率随CRAE、AVR减小而增加(P for trend均<0.05),与CRVE无关(P for trend>0.05)。T2DM患者的CRAE和AVR与年龄、性别、糖尿病病程、有无DR病史、有无DN病史、有无高血压病史均无交互作用(P for interaction均>0.05)。结论与无缺血性脑卒中病史的T2DM患者相比,有缺血性脑卒中病史的T2DM患者CRAE、AVR变小。T2DM患者缺血性脑卒中的患病率随CRAE、AVR减小而增加,与CRVE无关。展开更多
In order to predict the long-term rutting of asphalt pavement, the effective temperature for pavement rutting is calculated using the numerical simulation method. The transient temperature field of asphalt pavement wa...In order to predict the long-term rutting of asphalt pavement, the effective temperature for pavement rutting is calculated using the numerical simulation method. The transient temperature field of asphalt pavement was simulated based on actual meteorological data of Nanjing. 24-hour rutting development under a transient temperature field was calculated in each month. The rutting depth accumulated under the static temperature field was also estimated and the relationship between constant temperature parameters was analyzed. Then the effective temperature for pavement rutting was determined based on the rutting equivalence principle. The results show that the monthly effective temperature is above 40 t in July and August, while in June and September it ranges from 30 to 40 Rutting development can be ignored when the monthly effective temperature is less than 30 t. The yearly effective temperature for rutting in Nanjing is around 38. 5 t. The long-term rutting prediction model based on the effective temperature can reflect the influences of meteorological factors and traffic time distribution.展开更多
Firstly,the common design principles for diversion tunnel plug are generalized,and two kinds of numerical analysis methods are discussed.Then the strength reduction FEM is introduced in numerical model analysis and th...Firstly,the common design principles for diversion tunnel plug are generalized,and two kinds of numerical analysis methods are discussed.Then the strength reduction FEM is introduced in numerical model analysis and the design steps of the plug's length are illustrated.During the progress to determine the plug's length,the equivalent plastic strain on the potential slip surface is assumed as the flag to tell the failure against sliding,and the plug stability is overall estimated from the plastic zone range and connectivity.展开更多
Abstract. In this paper, we discuss the limit behaviour of solutious to equivalued surfaceboundary value problem for parabolic equations when the equivalued surface boundaryshrinks to a point and the space dimension o...Abstract. In this paper, we discuss the limit behaviour of solutious to equivalued surfaceboundary value problem for parabolic equations when the equivalued surface boundaryshrinks to a point and the space dimension of the domain is two or more.展开更多
文摘目的观察有缺血性脑卒中病史的2型糖尿病(T2DM)患者视网膜血管直径变化,并分析其临床意义。方法T2DM患者480例,根据有无缺血性脑卒中病史分为缺血性脑卒中组73例、非缺血性脑卒中组407例,使用眼底照相机和半自动测量软件ARIA测量视网膜动脉和静脉直径,计算视网膜中央静脉等效值(CRVE)、视网膜中央动脉等效值(CRAE)、动静脉比值(AVR)。收集患者的年龄、体质量指数(BMI)、吸烟史、饮酒史、高血压病史、糖尿病视网膜病变(DR)病史、糖尿病肾病(DN)病史等一般资料。将研究对象分别按照CRVE、CRAE、AVR四分位数分为4组,作为等级变量纳入logistic回归分析模型进行趋势性检验,以缺血性脑卒中患病率为因变量,分析T2DM患者视网膜血管直径与缺血性脑卒中患病率的关系。按年龄、性别、糖尿病病程、有无DR病史、有无DN病史、有无高血压病史进行分层,通过在logistic回归模型中包含交叉积交互项来检验CRAE、AVR与每个分层变量之间的交互作用,分析T2DM患者不同分层人群中视网膜血管直径与缺血性脑卒中患病率变化趋势的稳健性。结果缺血性脑卒中组患者CRVE、AVR均低于非缺血性脑卒中组(P均<0.05)。与非缺血性脑卒中组相比,缺血性脑卒中组患者年龄更大,糖尿病病程更长,有高血压、DN、DR病史者更多,SBP、SCr、Cys-C水平更高,TC、LDL-C水平更低(P均<0.05)。T2DM患者缺血性脑卒中的患病率随CRAE、AVR减小而增加(P for trend均<0.05),与CRVE无关(P for trend>0.05)。T2DM患者的CRAE和AVR与年龄、性别、糖尿病病程、有无DR病史、有无DN病史、有无高血压病史均无交互作用(P for interaction均>0.05)。结论与无缺血性脑卒中病史的T2DM患者相比,有缺血性脑卒中病史的T2DM患者CRAE、AVR变小。T2DM患者缺血性脑卒中的患病率随CRAE、AVR减小而增加,与CRVE无关。
基金The National Natural Science Foundation of China(No.51378121)the Fok Ying Tung Education Foundation(No.141076)the Scientific Innovation Research of College Graduates in Jiangsu Province(No.KYLX_0164)
文摘In order to predict the long-term rutting of asphalt pavement, the effective temperature for pavement rutting is calculated using the numerical simulation method. The transient temperature field of asphalt pavement was simulated based on actual meteorological data of Nanjing. 24-hour rutting development under a transient temperature field was calculated in each month. The rutting depth accumulated under the static temperature field was also estimated and the relationship between constant temperature parameters was analyzed. Then the effective temperature for pavement rutting was determined based on the rutting equivalence principle. The results show that the monthly effective temperature is above 40 t in July and August, while in June and September it ranges from 30 to 40 Rutting development can be ignored when the monthly effective temperature is less than 30 t. The yearly effective temperature for rutting in Nanjing is around 38. 5 t. The long-term rutting prediction model based on the effective temperature can reflect the influences of meteorological factors and traffic time distribution.
基金National Natural Science Foundation of China(No.50809051)
文摘Firstly,the common design principles for diversion tunnel plug are generalized,and two kinds of numerical analysis methods are discussed.Then the strength reduction FEM is introduced in numerical model analysis and the design steps of the plug's length are illustrated.During the progress to determine the plug's length,the equivalent plastic strain on the potential slip surface is assumed as the flag to tell the failure against sliding,and the plug stability is overall estimated from the plastic zone range and connectivity.
基金NSF of Shandong Province (No.Y98A09012, No. Q99A05.)
文摘Abstract. In this paper, we discuss the limit behaviour of solutious to equivalued surfaceboundary value problem for parabolic equations when the equivalued surface boundaryshrinks to a point and the space dimension of the domain is two or more.
