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一种新的长效制剂体外释放方法——等距浸出法 被引量:10
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作者 王世亮 储成顶 +2 位作者 刘飞 俞敏 鲍玉婷 《中国新药杂志》 CAS CSCD 北大核心 2003年第8期627-630,共4页
目的 :建立一种适用于长效药物的体外释放新方法。方法 :依据杯法原理 ,以断续浸出的方式进行长效制剂的体外释放试验 (等距浸出法 )并予数学证明。结果 :等距浸出法与杯法的数学模型相吻合 ,对比实验也揭示两法的试验结果呈显著性相关... 目的 :建立一种适用于长效药物的体外释放新方法。方法 :依据杯法原理 ,以断续浸出的方式进行长效制剂的体外释放试验 (等距浸出法 )并予数学证明。结果 :等距浸出法与杯法的数学模型相吻合 ,对比实验也揭示两法的试验结果呈显著性相关。结论 :等距浸出法简单实用 ,是一种较好的长效制剂的体外释放新方法。 展开更多
关键词 长效制剂 体外释放 等距浸出法 等时间距 等释放度距
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Bitmap lattice index in road networks
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作者 Doohee Song Keun-Ho Lee Kwangjin Park 《Journal of Central South University》 SCIE EI CAS 2014年第10期3856-3863,共8页
A novel technique called the bitmap lattice index(BLI) is proposed, which combines the advantages of a wireless broadcasting environment with a road network. Existing road networks are based on the on-demand method: a... A novel technique called the bitmap lattice index(BLI) is proposed, which combines the advantages of a wireless broadcasting environment with a road network. Existing road networks are based on the on-demand method: a server's workload increases as the query request increases when a server sends a client information. To solve this problem, we propose the BLI. The BLI denotes an object and a node as 0 and 1 in the Hilbert curve(HC) map. The BLI can identify the position of a node and an object through bit information; it can also reduce the broadcasting frequency of a server by reducing the size of the index, thereby decreasing the access latency and query processing times. Moreover, the BLI is highly effective for data filtering, as it can identify the positions of both an object and a node. In a road network, if filtering is done via the Euclidean distance, it may result in an error. To prevent this, we add another validation procedure. The experiment is conducted by applying the BLI to kNN query, and the technique is assessed by a performance evaluation experiment. 展开更多
关键词 road network wireless broadcast spatial query bitmap lattice index(BLI)
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