Aim To determine five organic acids in Radix Isatidis . Method The extraction method and the column partition chromatographic conditions were studied. Then a capillary zone electrophoretic method was set up for t...Aim To determine five organic acids in Radix Isatidis . Method The extraction method and the column partition chromatographic conditions were studied. Then a capillary zone electrophoretic method was set up for the determination. Results The linear ranges of quinazolinone acid, n anthranilic acid, benzoic acid, salicylic acid, and syringic acid were 5 52-92 0 μg·mL -1 , 5 12-102 μg·mL -1 , 2 28-84 4 μg·mL-1 , 4 78-159 μg·mL -1 , and 1 74-87 0 μg·mL -1 respectively. Conclusion The established method is accurate and simple.展开更多
A three-dimensional finite element approach based on ABAQUS code was developed to investigate the effect of welding sequence on welding residual stress distribution in a thin-walled 6061 aluminum alloy structure. To o...A three-dimensional finite element approach based on ABAQUS code was developed to investigate the effect of welding sequence on welding residual stress distribution in a thin-walled 6061 aluminum alloy structure. To obtain sound numerical results, the therrno-mechanical behaviour was simulated using a direct-coupled formulation. Nine different simulation sequences were carried out by single-pass TIG welding of an octagonal pipe-plate joint, and the distributions of longitudinal and transverse residual stresses both on the outer and inner surfaces of the pipe were analyzed. The results suggest that the final residual stresses in the weld and its vicinity are not affected by the initial residual stresses of the structure. Selecting a suitable welding sequence can reduce the final residual stress in an octagonal pipe-plate joint.展开更多
In this paper, the measurement of liquid mixing in a downcomer of segmental type of distillation column is presented. The extent of liquid mixing is calculated by means of a mixing pool model. The results indicate tha...In this paper, the measurement of liquid mixing in a downcomer of segmental type of distillation column is presented. The extent of liquid mixing is calculated by means of a mixing pool model. The results indicate that liquid mixing in a downcomer is actually incomplete. It is a significant correction to the assumption of complete downcomer mixing or no downcomer mixing which is generally adopted in many distillation calculations. Besides, the present results are used in a two dimensional eddy diffusion model to calculate the distillation tray efficiency. It is shown that the assumption of complete downcomer mixing is closer to the actual situation than that of no downcomer mixing.展开更多
In an attempt to demonstrate the biological activities of a short peptide.Arg-Gly-Asp- Ser (RGDS) was synthesized and used for bioassay,The data obtained here proved that RGDS ob- viously inhibited PAF- and/or ADP-ind...In an attempt to demonstrate the biological activities of a short peptide.Arg-Gly-Asp- Ser (RGDS) was synthesized and used for bioassay,The data obtained here proved that RGDS ob- viously inhibited PAF- and/or ADP-induced platelet aggregation.The present paper revealed that RG- DS had vasodilative action and the cGMP accumulation may be one of the mechanisms of RGDS exer- ting bioactivities.展开更多
We present a general approach to fabricate metal/TiO2 core/shell nanorod structures by twostep electrodeposition. Firstly, TiO2 nanotubes with uniform wall thickness are prepared in anodic aluminum oxide (AAO) membr...We present a general approach to fabricate metal/TiO2 core/shell nanorod structures by twostep electrodeposition. Firstly, TiO2 nanotubes with uniform wall thickness are prepared in anodic aluminum oxide (AAO) membranes by electrodeposition. The wall thickness of the nanotubes could be easily controlled by modulating the deposition time, and their outer diameter and length are only limited by the channel diameter and the thickness of the AAO membranes, respectively. The nanotubes' tops prepared by this method are open, while the bottoms are connected directly with the Au film at the back of the AAO membranes. Secondly, Pd, Cu, and Fe elements are filled into the TiO2 nanotubes to form core/shell structures. The core/shell nanorods prepared by this two-step process are high density and free-standing, and their length is dependent on the deposition time.展开更多
Temperature distribution over the absorber plate of a parallel flow flat-plate solar collector is numerically analyzed. The governing differential equations with boundary conditions are solved numerically using fluent...Temperature distribution over the absorber plate of a parallel flow flat-plate solar collector is numerically analyzed. The governing differential equations with boundary conditions are solved numerically using fluent software. Effects of the inlet mass flux, inlet temperature and tube spacing on velocity and temperature distributions are discussed. Numerical results show that the distributions of velocity and temperature of fluid is unsymmetrical inside pipe.展开更多
The rockburst of the poal pillar under a thick hard roof stratum is modelled as the instability failure problem of coal pillars under strata subject to elastic support. The instability mechanism of rockburst is studie...The rockburst of the poal pillar under a thick hard roof stratum is modelled as the instability failure problem of coal pillars under strata subject to elastic support. The instability mechanism of rockburst is studied by applying cusp catastrophic theory. The effects of the stiffness ratio of the system and loads imposed on the system on the rockburst are explicated.The factors affecting rockbursts are discussed. Based on them, the evolution process, the forewarning regularity arid forewarning sings of rockbursts are studied. It is indicated that the subsidence velocity of roof stratum, which increases quickly and tends to infinity, is the forewarning measurable signs of the rockbursts of coal pillar.展开更多
Titanium tube and stainless steel tube plate were welded by an innovative friction welding of tube to tube plate using an external tool (FWTPET). Copper was used as an interlayer for joining the dissimilar materials a...Titanium tube and stainless steel tube plate were welded by an innovative friction welding of tube to tube plate using an external tool (FWTPET). Copper was used as an interlayer for joining the dissimilar materials and also to minimize the effect of intermetallics formed at the joint interface. The process parameters that govern FWTPET process are plunge rate, rotational speed, plunge depth, axial load and flash trap profile. Among them, the flash trap profile of the tube has a significant influence on the joint integrity. Various flash trap profiles like vertical slots, holes, zig-zag holes, and petals were made on the titanium tube welded to the stainless steel tube plate. Macroscopic and microscopic studies reveal defect-free joints. The presence of copper interlayer and intermetallics was evident from X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) studies. The microhardness survey was presented across and along the interface. A novel test procedure called “plunge shear test” was developed to evaluate the joint properties of the welded joints. The highest shear fracture load of 31.58 kN was observed on the sample having petals as flash trap profile. The sheared surfaces were further characterized using SEM for fractography.展开更多
Prion diseases are a group of neurodegenerative diseases that are fatal. The study of these unique diseases in China is hampered by a lack of resources. Amongst the most important resources for biological study are mo...Prion diseases are a group of neurodegenerative diseases that are fatal. The study of these unique diseases in China is hampered by a lack of resources. Amongst the most important resources for biological study are monoclonal antibodies. Here, we characterize a panel of monoclonal antibodies specific for cellular prion protein by enzyme-linked immunosorbent assay(ELISA), immunofluorescent staining, flow cytometry, and western blotting. We identify several antibodies that can be used for specific applications and we demonstrate that there is no prion protein expression in human pancreatic ductal epithelial cells(HPDC).展开更多
Described the outcomes of a comprehensive numerical modeling on the rock bolting performance for preventing the deformation of stratified, composite roof structure of drift in a coal mine. The investigation was undert...Described the outcomes of a comprehensive numerical modeling on the rock bolting performance for preventing the deformation of stratified, composite roof structure of drift in a coal mine. The investigation was undertaken in the adverse geological condi- tions, with variation of bolt parameters, including length, density, distribution, pretension, as well as the geometry of opening,so as to determine the effect of bolting parameter variation on roof deformation and stability. The outcomes clearly demonstrated that a sig- nificant improvement of roof stability can be achieved associating with bolting parameters optimization, and indicated the importance of flexible geotechnical designation of rock bolting reinforcement in mining practice.展开更多
H-H joint of "H-jointed SPSP with H-H joint", which is made up of interlocking two H-steel sections of different sizes, is the one of SPSP's joint to improve the hydraulic conductivity. "H-H jointed SPSP with H-H ...H-H joint of "H-jointed SPSP with H-H joint", which is made up of interlocking two H-steel sections of different sizes, is the one of SPSP's joint to improve the hydraulic conductivity. "H-H jointed SPSP with H-H joint" is expected to be applied to a vertical cutoff wall in coastal landfill sites. In H-jointed SPSP with H-H joint, the H-joint is completely imperviousness. H-H joint, however, is pervious at interlocked state because a gap of 8 to 11 mm is left between the interlocking flanges, therefore, a water interception treatment must be conducted to seal the gap. The water shielding treatment of H-H joint is executed by coating the gaps with a water-swelling sheet of paint before its installation. Then, hollow space is generated in H-H joint after treating by water-swelling sheet, and that space can be used effectively. This paper proposes leachate control technologies using H-H joint interior space of SPSP cutoff walls. The possibility of those technologies and hydraulic conductivity of H-jointed SPSP with H-H joints are demonstrated by conducting the hydraulic conductivity test.展开更多
Understanding roof behaviour and immediate roof failure patterns of longwall face is a prerequisite for establishing correct roof control theory and appplying effective roof control measures. Roof behaviour and immedi...Understanding roof behaviour and immediate roof failure patterns of longwall face is a prerequisite for establishing correct roof control theory and appplying effective roof control measures. Roof behaviour and immediate roof failure pattern have a close relationship with upper mining boundary conditions of longwall face. According to actual situation of Datong Mining Area,upper mining boundary conditions of longwall face have been classified into 5 types in this paper.Roof behaviour and immediate roof failure pattern under each upper mining boundary condition are discussed in details.展开更多
A stress analysis is described for a nuclear steam generator tubesheet with a thin, or irregular ligament, associated with a mis-drilled hole using the rules of ASME (American Society of Mechanical Engineers) B & P...A stress analysis is described for a nuclear steam generator tubesheet with a thin, or irregular ligament, associated with a mis-drilled hole using the rules of ASME (American Society of Mechanical Engineers) B & PV Section Ⅲ and non-mandatory Appendix A, Article A-8000 for stresses in perforated flat plates. The analysis demonstrates the proper application of the NB-3200 rules for this special application, with discussion of the differences between an actual tube hole deviation and what is assumed in ASME Appendix A. This is a companion paper to "Technical Justification Supporting Operation with a Tube Installed in a Mis-Drilled Hole of a Steam Generator Tubesheet".展开更多
The run-around of Xiagou subincline bottom is a soft rock roadway, its floor has heaved over 1 m. ln this paper, by electronic microscope scanning and X-ray diffraction analy-sis, the components of the soft rock are d...The run-around of Xiagou subincline bottom is a soft rock roadway, its floor has heaved over 1 m. ln this paper, by electronic microscope scanning and X-ray diffraction analy-sis, the components of the soft rock are determined and the breaking mechanism of roadway is analyzed as well. Through finite element calculation and simulation model test, the reasonable repair support method is put forward.展开更多
This paper briefly introduces the wisdom of management contained in the quintessence of the wisdom of Chinese ancient sages "The quintessence of wisdom in books of all sorts", and explores the application of the tra...This paper briefly introduces the wisdom of management contained in the quintessence of the wisdom of Chinese ancient sages "The quintessence of wisdom in books of all sorts", and explores the application of the traditional Chinese wisdom in resolving vari- ous dilemmas or crisis in today's human society, to help the society, the nation, and the enterprises solve the management problems.展开更多
A novel full color SOP(system on panel) AMOLED display based on the MIUC polycrystalline silicon TFT technique, and a new control circuit for the panel, which can deal with both VGA and DVI input signals have been d...A novel full color SOP(system on panel) AMOLED display based on the MIUC polycrystalline silicon TFT technique, and a new control circuit for the panel, which can deal with both VGA and DVI input signals have been developed. To realize gray-scale a sub-frame technique has been designed and im- plemented by FPGA device, in which an 120 module has been inserted. Through actual circuit, the whole design has been proven and the advantages of the SOP AMOLED display panel have been confirmed.展开更多
To clarify and control the collapse and weighting of main roof in longwall mining is one of the important research problems in ground control. Based on the results of physical model experiment and field measurement, t...To clarify and control the collapse and weighting of main roof in longwall mining is one of the important research problems in ground control. Based on the results of physical model experiment and field measurement, the behaviour of main roof above trapezoidal goaf or with fault is studied in this paper. The fracture and weighting of main roof above trapezoidal goaf are different from those above rectangular goaf. It depends on the mechanical relation between main roof blocks whether the plate blocks of main roof on both sides of fault simultaneously break and collapse.展开更多
This paper presents an experimental study on a flat plate closed loop pulsating heat pipes. It consisted of total 40 channels with square cross section (2 × 2 mm^2, 165 mm long) machined directly on an aluminum...This paper presents an experimental study on a flat plate closed loop pulsating heat pipes. It consisted of total 40 channels with square cross section (2 × 2 mm^2, 165 mm long) machined directly on an aluminum plate(180×120×3 nm^2), which was covered by a transparent plate. The working fluid employed was ethanol. As the results, the influence parameters of thermal performance were investigated, such as filling ratio, heat load and operational orientations etc. Filling ratio was found to be a critical parameter, and its effect was rather complicated. According to its values the PHP plate could have four distinct working zones with different operational characteristics and heat transfer performance. The effect of heat load on thermal performance was found to be positive, and in general, iucrcasing the heat load would improve heat transfer performance. In order to analyze the effect of gravity on thermal performance, three different heat modes and total seven tilt angles were tested and compared. Successful operation at all orientations with respect to gravity was also achieved.展开更多
文摘Aim To determine five organic acids in Radix Isatidis . Method The extraction method and the column partition chromatographic conditions were studied. Then a capillary zone electrophoretic method was set up for the determination. Results The linear ranges of quinazolinone acid, n anthranilic acid, benzoic acid, salicylic acid, and syringic acid were 5 52-92 0 μg·mL -1 , 5 12-102 μg·mL -1 , 2 28-84 4 μg·mL-1 , 4 78-159 μg·mL -1 , and 1 74-87 0 μg·mL -1 respectively. Conclusion The established method is accurate and simple.
基金Project(61075005)supported by the Fund of State Key Laboratory of Advanced Design and Manufacture for Vehicle Body in Hunan University,ChinaProject(09JJ1007)supported by Preeminent Youth Fund of Hunan Province,ChinaProject(51075132)supported by the National Natural Science Foundation of China
文摘A three-dimensional finite element approach based on ABAQUS code was developed to investigate the effect of welding sequence on welding residual stress distribution in a thin-walled 6061 aluminum alloy structure. To obtain sound numerical results, the therrno-mechanical behaviour was simulated using a direct-coupled formulation. Nine different simulation sequences were carried out by single-pass TIG welding of an octagonal pipe-plate joint, and the distributions of longitudinal and transverse residual stresses both on the outer and inner surfaces of the pipe were analyzed. The results suggest that the final residual stresses in the weld and its vicinity are not affected by the initial residual stresses of the structure. Selecting a suitable welding sequence can reduce the final residual stress in an octagonal pipe-plate joint.
文摘In this paper, the measurement of liquid mixing in a downcomer of segmental type of distillation column is presented. The extent of liquid mixing is calculated by means of a mixing pool model. The results indicate that liquid mixing in a downcomer is actually incomplete. It is a significant correction to the assumption of complete downcomer mixing or no downcomer mixing which is generally adopted in many distillation calculations. Besides, the present results are used in a two dimensional eddy diffusion model to calculate the distillation tray efficiency. It is shown that the assumption of complete downcomer mixing is closer to the actual situation than that of no downcomer mixing.
基金This project was supported by the National Natural Science Foundation
文摘In an attempt to demonstrate the biological activities of a short peptide.Arg-Gly-Asp- Ser (RGDS) was synthesized and used for bioassay,The data obtained here proved that RGDS ob- viously inhibited PAF- and/or ADP-induced platelet aggregation.The present paper revealed that RG- DS had vasodilative action and the cGMP accumulation may be one of the mechanisms of RGDS exer- ting bioactivities.
基金This work is supported by the National Natural Science Foundation of China (No.10574122, No.50772110, No.50721091) and the National Basic Research Program of China (No.2011CB921400, No.2007CB925202, No.2009CB939901).
文摘We present a general approach to fabricate metal/TiO2 core/shell nanorod structures by twostep electrodeposition. Firstly, TiO2 nanotubes with uniform wall thickness are prepared in anodic aluminum oxide (AAO) membranes by electrodeposition. The wall thickness of the nanotubes could be easily controlled by modulating the deposition time, and their outer diameter and length are only limited by the channel diameter and the thickness of the AAO membranes, respectively. The nanotubes' tops prepared by this method are open, while the bottoms are connected directly with the Au film at the back of the AAO membranes. Secondly, Pd, Cu, and Fe elements are filled into the TiO2 nanotubes to form core/shell structures. The core/shell nanorods prepared by this two-step process are high density and free-standing, and their length is dependent on the deposition time.
文摘Temperature distribution over the absorber plate of a parallel flow flat-plate solar collector is numerically analyzed. The governing differential equations with boundary conditions are solved numerically using fluent software. Effects of the inlet mass flux, inlet temperature and tube spacing on velocity and temperature distributions are discussed. Numerical results show that the distributions of velocity and temperature of fluid is unsymmetrical inside pipe.
文摘The rockburst of the poal pillar under a thick hard roof stratum is modelled as the instability failure problem of coal pillars under strata subject to elastic support. The instability mechanism of rockburst is studied by applying cusp catastrophic theory. The effects of the stiffness ratio of the system and loads imposed on the system on the rockburst are explicated.The factors affecting rockbursts are discussed. Based on them, the evolution process, the forewarning regularity arid forewarning sings of rockbursts are studied. It is indicated that the subsidence velocity of roof stratum, which increases quickly and tends to infinity, is the forewarning measurable signs of the rockbursts of coal pillar.
基金financial support provided by UGC-DAE-CSR (CSR-KN/CRS-04/201213/738) through fellowship
文摘Titanium tube and stainless steel tube plate were welded by an innovative friction welding of tube to tube plate using an external tool (FWTPET). Copper was used as an interlayer for joining the dissimilar materials and also to minimize the effect of intermetallics formed at the joint interface. The process parameters that govern FWTPET process are plunge rate, rotational speed, plunge depth, axial load and flash trap profile. Among them, the flash trap profile of the tube has a significant influence on the joint integrity. Various flash trap profiles like vertical slots, holes, zig-zag holes, and petals were made on the titanium tube welded to the stainless steel tube plate. Macroscopic and microscopic studies reveal defect-free joints. The presence of copper interlayer and intermetallics was evident from X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) studies. The microhardness survey was presented across and along the interface. A novel test procedure called “plunge shear test” was developed to evaluate the joint properties of the welded joints. The highest shear fracture load of 31.58 kN was observed on the sample having petals as flash trap profile. The sheared surfaces were further characterized using SEM for fractography.
基金the National Natural Sciences Foundation of China(81172376,31270209)the 100 talent-program of the Chinese Academy of Sciencesthe State Key Laboratory of Virology for financial support
文摘Prion diseases are a group of neurodegenerative diseases that are fatal. The study of these unique diseases in China is hampered by a lack of resources. Amongst the most important resources for biological study are monoclonal antibodies. Here, we characterize a panel of monoclonal antibodies specific for cellular prion protein by enzyme-linked immunosorbent assay(ELISA), immunofluorescent staining, flow cytometry, and western blotting. We identify several antibodies that can be used for specific applications and we demonstrate that there is no prion protein expression in human pancreatic ductal epithelial cells(HPDC).
文摘Described the outcomes of a comprehensive numerical modeling on the rock bolting performance for preventing the deformation of stratified, composite roof structure of drift in a coal mine. The investigation was undertaken in the adverse geological condi- tions, with variation of bolt parameters, including length, density, distribution, pretension, as well as the geometry of opening,so as to determine the effect of bolting parameter variation on roof deformation and stability. The outcomes clearly demonstrated that a sig- nificant improvement of roof stability can be achieved associating with bolting parameters optimization, and indicated the importance of flexible geotechnical designation of rock bolting reinforcement in mining practice.
文摘H-H joint of "H-jointed SPSP with H-H joint", which is made up of interlocking two H-steel sections of different sizes, is the one of SPSP's joint to improve the hydraulic conductivity. "H-H jointed SPSP with H-H joint" is expected to be applied to a vertical cutoff wall in coastal landfill sites. In H-jointed SPSP with H-H joint, the H-joint is completely imperviousness. H-H joint, however, is pervious at interlocked state because a gap of 8 to 11 mm is left between the interlocking flanges, therefore, a water interception treatment must be conducted to seal the gap. The water shielding treatment of H-H joint is executed by coating the gaps with a water-swelling sheet of paint before its installation. Then, hollow space is generated in H-H joint after treating by water-swelling sheet, and that space can be used effectively. This paper proposes leachate control technologies using H-H joint interior space of SPSP cutoff walls. The possibility of those technologies and hydraulic conductivity of H-jointed SPSP with H-H joints are demonstrated by conducting the hydraulic conductivity test.
文摘Understanding roof behaviour and immediate roof failure patterns of longwall face is a prerequisite for establishing correct roof control theory and appplying effective roof control measures. Roof behaviour and immediate roof failure pattern have a close relationship with upper mining boundary conditions of longwall face. According to actual situation of Datong Mining Area,upper mining boundary conditions of longwall face have been classified into 5 types in this paper.Roof behaviour and immediate roof failure pattern under each upper mining boundary condition are discussed in details.
文摘A stress analysis is described for a nuclear steam generator tubesheet with a thin, or irregular ligament, associated with a mis-drilled hole using the rules of ASME (American Society of Mechanical Engineers) B & PV Section Ⅲ and non-mandatory Appendix A, Article A-8000 for stresses in perforated flat plates. The analysis demonstrates the proper application of the NB-3200 rules for this special application, with discussion of the differences between an actual tube hole deviation and what is assumed in ASME Appendix A. This is a companion paper to "Technical Justification Supporting Operation with a Tube Installed in a Mis-Drilled Hole of a Steam Generator Tubesheet".
文摘The run-around of Xiagou subincline bottom is a soft rock roadway, its floor has heaved over 1 m. ln this paper, by electronic microscope scanning and X-ray diffraction analy-sis, the components of the soft rock are determined and the breaking mechanism of roadway is analyzed as well. Through finite element calculation and simulation model test, the reasonable repair support method is put forward.
文摘This paper briefly introduces the wisdom of management contained in the quintessence of the wisdom of Chinese ancient sages "The quintessence of wisdom in books of all sorts", and explores the application of the traditional Chinese wisdom in resolving vari- ous dilemmas or crisis in today's human society, to help the society, the nation, and the enterprises solve the management problems.
文摘A novel full color SOP(system on panel) AMOLED display based on the MIUC polycrystalline silicon TFT technique, and a new control circuit for the panel, which can deal with both VGA and DVI input signals have been developed. To realize gray-scale a sub-frame technique has been designed and im- plemented by FPGA device, in which an 120 module has been inserted. Through actual circuit, the whole design has been proven and the advantages of the SOP AMOLED display panel have been confirmed.
文摘To clarify and control the collapse and weighting of main roof in longwall mining is one of the important research problems in ground control. Based on the results of physical model experiment and field measurement, the behaviour of main roof above trapezoidal goaf or with fault is studied in this paper. The fracture and weighting of main roof above trapezoidal goaf are different from those above rectangular goaf. It depends on the mechanical relation between main roof blocks whether the plate blocks of main roof on both sides of fault simultaneously break and collapse.
基金Supported by the Ger man National Science Foundation (DFG)(No. GR412/33)
文摘This paper presents an experimental study on a flat plate closed loop pulsating heat pipes. It consisted of total 40 channels with square cross section (2 × 2 mm^2, 165 mm long) machined directly on an aluminum plate(180×120×3 nm^2), which was covered by a transparent plate. The working fluid employed was ethanol. As the results, the influence parameters of thermal performance were investigated, such as filling ratio, heat load and operational orientations etc. Filling ratio was found to be a critical parameter, and its effect was rather complicated. According to its values the PHP plate could have four distinct working zones with different operational characteristics and heat transfer performance. The effect of heat load on thermal performance was found to be positive, and in general, iucrcasing the heat load would improve heat transfer performance. In order to analyze the effect of gravity on thermal performance, three different heat modes and total seven tilt angles were tested and compared. Successful operation at all orientations with respect to gravity was also achieved.