Objective To determine the safety and efficacy of fresh frozen plasma （FFP） iniusion for the treat- ment of hereditary angioedema （FIAE）. Methods The medical records of patients with HAE admitted to Peking Union ...Objective To determine the safety and efficacy of fresh frozen plasma （FFP） iniusion for the treat- ment of hereditary angioedema （FIAE）. Methods The medical records of patients with HAE admitted to Peking Union Medical College Fiospital who had received FFP infusion during 2004 and 2010 were reviewed and PubMed database iFom 1966 to the present were searched using the following key words： hereditary angioedema and fresh frozen plasma. The patient＇s age, sex, body location of HAE attacks, the dose of FFP infusion, time of beginning to improvenaent, time to complete remission, complication, C 1 inhibitor activity, and outcome were analyzed. Results A total of 13 enrolled patients （7 male and 6 female） received 16 times of FFP infusion, in- cluding 2 patients undergoing FFP infusion in Peking Union Medical College Hospital and 11 patients re- ported in the literature. The mean dosage of FFP infusion was 586±337 mL. Two cases suffered from wors- ening abdominal pain and one case experienced skin rash. Only I patient had no improvement in symptom owing to transfusion related reaction. There was a definite improvement in symptom 49± 19 minutes after beginning FFP infusion. The remission time decreased from 61.7±27.0 hours to 3.3 （2.0, 12.0） hours after FFP infusion. FFP infusion was effective for both type I and type Ⅱ HAE. Conclusion FFP seems to be safe and effective for acute attacks of HAE.展开更多
AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a publi...AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a public hospital,were retrospectively reviewed.Gallbladder pathology was diagnosed by history,physical examination,and laboratory and imaging studies [ultrasonography and computed tomography(CT)].Patients with gallbladder cancer(GBC) were further analyzed for demographic data,and type of operation,surgical morbidity and mortality,histopathological classification,and survival.Incidental GBC was compared with suspected or preoperatively diagnosed GBC.The primary endpoint was diseasefree survival(DFS).The secondary endpoint was the difference in DFS between patients previously treated with laparoscopic cholecystectomy and those who had oncological resection as first intervention.RESULTS:Nineteen patients(11 women and eight men) were found to have GBC.The male to female ratio was 1:1.4 and the mean age was 68 years(range:45-82 years).Preoperative diagnosis was made in 10 cases,and eight were diagnosed postoperatively.One was suspected intraoperatively and confirmed by frozen sections.The ratio between incidental and nonincidental cases was 9/19.The tumor node metastasis stage was:pTis(1),pT1a(2),pT1b(4),pT2(6),pT3(4),pT4(2);five cases with stageⅠa(T1 a-b);two with stageⅠb(T2 N0);one with stage Ⅱa(T3 N0);six with stage Ⅱb(T1-T3 N1);two with stage Ⅲ(T4 Nx Nx);and one with stage Ⅳ(Tx Nx Mx).Eighty-eight percent of the incidental cases were discovered at an early stage(≤Ⅱ).Preoperative diagnosis of the 19 patients with GBC was:GBC with liver invasion diagnosed by preoperative CT(nine cases),gallbladder abscess perforated into hepatic parenchyma and involving the transversal mesocolon and hepatic hilum(one case),porcelain gallbladder(one case),gallbladder adenoma(one case),and chronic cholelithiasis(eight cases).Every case,except one,with a T1b or more advanced invasion underwent Ⅳb + Ⅴ wedge liver resection and pericholedochic/hepatoduodenal lymphadenectomy.One patient with stage T1b GBC refused further surgery.Cases with Tis and T1a involvement were treated with cholecystectomy alone.One incidental case was diagnosed by intraoperative frozen section and treated with cholecystectomy alone.Six of the nine patients with incidental diagnosis reached 5-year DFS.One patient reached 38 mo survival despite a port-site recurrence 2 years after original surgery.Cases with non incidental diagnosis were more locally advanced and only two patients experienced 5-year DFS.CONCLUSION:Laparoscopic cholecystectomy does not affect survival if implemented properly.Reoperation should have two objectives:R0 resection and clearance of the lymph nodes.展开更多
An improved topographic database for King George Island,one of the most frequently visited regions in Antarctica,is presented.A first step consisted in combining data from differential GPS surveys gained during the au...An improved topographic database for King George Island,one of the most frequently visited regions in Antarctica,is presented.A first step consisted in combining data from differential GPS surveys gained during the austral summers 1997～1998 and 1999～2000,with the current coastline from a SPOT satellite image mosaic,topographic information from existing maps and from the Antarctic Digital Database.From this data sets,a digital terrain model (DTM) was generated using Arc/Info GIS.In a second step,a satellite image map at the scale 1∶100 000 was assembled from contour lines derived from the DTM and the satellite mosaic.A lack of accurate topographic information in the eastern part of the island was identified.Additional topographic surveying or SAR interferometry should be used to improve the data quality in that area.The GIS integrated database will be indispensable for glaciological and climatological studies and administrative and scientific purposes.In future,the application of GIS techniques will be mandatory for environmental impact studies and environmental monitoring as well as for management plans on King George Island.展开更多
In order to maintain the health and vigour and to sustain the productivity, a pruning experiment was conducted on four year old ＂Balwant＂ cultivar of aonla grown in laterite soil, planted at a spacing of 5m×5m....In order to maintain the health and vigour and to sustain the productivity, a pruning experiment was conducted on four year old ＂Balwant＂ cultivar of aonla grown in laterite soil, planted at a spacing of 5m×5m. To find out the best pruning method, six levels of pruning was performed i.e., （1） Light judicious pruning, （2） Detopping of primary branches at 8 feet from ground level ＋ removal of all secondary branches, （3） Detopping of primary branches at 8 feet from the ground level ＋ removal of all secondary branches at 2 feet from the base of primary branches, （4） Detopping of primary branches at 8 feet from the ground level ＋ removal of all secondary branches at 1 feet from the base of primary branches, （5） Light judicious pruning ＋ Detopping of plant canopy of at 8 feet from the ground level, （6） No pruning （control）. Results of three consecutive years of investigation revealed that light judicious pruning of thin, overlapping, criss-crossed, dead, unproductive and looping branches gave highest fruit yield in all the three years and resulted 64.4 percent yield increment over control when average of three years was considered. Severe pruning of primary and secondary branches caused drastic reduction of yield for two consecutive years after pruning. Judicious pruning helped to produce better sizeable and quality fruits.展开更多
A dynamic experimental apparatus to measure the instantaneous velocity and pressure in the multi-bypass pulse tube refrigerator (MPTR) was designed and constructed. Some theortant experimental results of the instantan...A dynamic experimental apparatus to measure the instantaneous velocity and pressure in the multi-bypass pulse tube refrigerator (MPTR) was designed and constructed. Some theortant experimental results of the instantaneous measurements of the velocity and the pressure in the MPTR with two-bypass tubes during actual operation are presented. The effects of the middle-bypass version on the dynamic pressure and mass flow rate at the cold end of the pulse tube are evaluated from experimental measurements.DC-flow phenomena are observed in this MPTR. The reasons of the multi-bypass version improved the performance of pulse tube refrigerator are given.展开更多
In this paper, a novel system using direct contact heat transfer between air and water solution was proposed to generate ice slurry. The heat transfer process and the system performance were studied; energy efficiency...In this paper, a novel system using direct contact heat transfer between air and water solution was proposed to generate ice slurry. The heat transfer process and the system performance were studied; energy efficiency coefficients of 0.038, 0.053, and 0.064 were obtained using different solutions. An empirical relationship between the volumetric heat transfer coefficient U v and the main parameters was obtained by fitting the experimental data. The U v calculated from the empirical formula agreed with the experimental U v quite well with a relative error of less than 15%. Based on the empirical formula, a laboratory-scale direct contact ice slurry generator was then constructed, with practical application in mind. If the air flow rate is fixed at 200 m 3 /h, the ice production rate will be 0.091 kg/min. The experimental results also showed that the cold energy consumption of the air compressor accounted for more than half of the total amount. To improve the system energy efficiency coefficient, it is necessary to increase the air pipes insulation and the solution's thermal capacity, and also it is appropriate to utilize the free cold energy of liquefied natural gas (LNG).展开更多
This paper reports the experiments of evaporation study in 6 mm inner copper diamter tubes us-ing HFC-134a, HCFC-22 and CFC-12 as working nuid. The results show that the evaporation heat transfer coefficient increases...This paper reports the experiments of evaporation study in 6 mm inner copper diamter tubes us-ing HFC-134a, HCFC-22 and CFC-12 as working nuid. The results show that the evaporation heat transfer coefficient increases with the decreasing of inner diameter of tubes. A new concept of non-dimensional tube diameter U is proposed in this paper for correction of the influence of the tube diameter on the evaporation heat transfer coefficient. And further, a convnient empirical correction mehod is pented.展开更多
文摘Objective To determine the safety and efficacy of fresh frozen plasma （FFP） iniusion for the treat- ment of hereditary angioedema （FIAE）. Methods The medical records of patients with HAE admitted to Peking Union Medical College Fiospital who had received FFP infusion during 2004 and 2010 were reviewed and PubMed database iFom 1966 to the present were searched using the following key words： hereditary angioedema and fresh frozen plasma. The patient＇s age, sex, body location of HAE attacks, the dose of FFP infusion, time of beginning to improvenaent, time to complete remission, complication, C 1 inhibitor activity, and outcome were analyzed. Results A total of 13 enrolled patients （7 male and 6 female） received 16 times of FFP infusion, in- cluding 2 patients undergoing FFP infusion in Peking Union Medical College Hospital and 11 patients re- ported in the literature. The mean dosage of FFP infusion was 586±337 mL. Two cases suffered from wors- ening abdominal pain and one case experienced skin rash. Only I patient had no improvement in symptom owing to transfusion related reaction. There was a definite improvement in symptom 49± 19 minutes after beginning FFP infusion. The remission time decreased from 61.7±27.0 hours to 3.3 （2.0, 12.0） hours after FFP infusion. FFP infusion was effective for both type I and type Ⅱ HAE. Conclusion FFP seems to be safe and effective for acute attacks of HAE.
文摘AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a public hospital,were retrospectively reviewed.Gallbladder pathology was diagnosed by history,physical examination,and laboratory and imaging studies [ultrasonography and computed tomography(CT)].Patients with gallbladder cancer(GBC) were further analyzed for demographic data,and type of operation,surgical morbidity and mortality,histopathological classification,and survival.Incidental GBC was compared with suspected or preoperatively diagnosed GBC.The primary endpoint was diseasefree survival(DFS).The secondary endpoint was the difference in DFS between patients previously treated with laparoscopic cholecystectomy and those who had oncological resection as first intervention.RESULTS:Nineteen patients(11 women and eight men) were found to have GBC.The male to female ratio was 1:1.4 and the mean age was 68 years(range:45-82 years).Preoperative diagnosis was made in 10 cases,and eight were diagnosed postoperatively.One was suspected intraoperatively and confirmed by frozen sections.The ratio between incidental and nonincidental cases was 9/19.The tumor node metastasis stage was:pTis(1),pT1a(2),pT1b(4),pT2(6),pT3(4),pT4(2);five cases with stageⅠa(T1 a-b);two with stageⅠb(T2 N0);one with stage Ⅱa(T3 N0);six with stage Ⅱb(T1-T3 N1);two with stage Ⅲ(T4 Nx Nx);and one with stage Ⅳ(Tx Nx Mx).Eighty-eight percent of the incidental cases were discovered at an early stage(≤Ⅱ).Preoperative diagnosis of the 19 patients with GBC was:GBC with liver invasion diagnosed by preoperative CT(nine cases),gallbladder abscess perforated into hepatic parenchyma and involving the transversal mesocolon and hepatic hilum(one case),porcelain gallbladder(one case),gallbladder adenoma(one case),and chronic cholelithiasis(eight cases).Every case,except one,with a T1b or more advanced invasion underwent Ⅳb + Ⅴ wedge liver resection and pericholedochic/hepatoduodenal lymphadenectomy.One patient with stage T1b GBC refused further surgery.Cases with Tis and T1a involvement were treated with cholecystectomy alone.One incidental case was diagnosed by intraoperative frozen section and treated with cholecystectomy alone.Six of the nine patients with incidental diagnosis reached 5-year DFS.One patient reached 38 mo survival despite a port-site recurrence 2 years after original surgery.Cases with non incidental diagnosis were more locally advanced and only two patients experienced 5-year DFS.CONCLUSION:Laparoscopic cholecystectomy does not affect survival if implemented properly.Reoperation should have two objectives:R0 resection and clearance of the lymph nodes.
文摘An improved topographic database for King George Island,one of the most frequently visited regions in Antarctica,is presented.A first step consisted in combining data from differential GPS surveys gained during the austral summers 1997～1998 and 1999～2000,with the current coastline from a SPOT satellite image mosaic,topographic information from existing maps and from the Antarctic Digital Database.From this data sets,a digital terrain model (DTM) was generated using Arc/Info GIS.In a second step,a satellite image map at the scale 1∶100 000 was assembled from contour lines derived from the DTM and the satellite mosaic.A lack of accurate topographic information in the eastern part of the island was identified.Additional topographic surveying or SAR interferometry should be used to improve the data quality in that area.The GIS integrated database will be indispensable for glaciological and climatological studies and administrative and scientific purposes.In future,the application of GIS techniques will be mandatory for environmental impact studies and environmental monitoring as well as for management plans on King George Island.
文摘In order to maintain the health and vigour and to sustain the productivity, a pruning experiment was conducted on four year old ＂Balwant＂ cultivar of aonla grown in laterite soil, planted at a spacing of 5m×5m. To find out the best pruning method, six levels of pruning was performed i.e., （1） Light judicious pruning, （2） Detopping of primary branches at 8 feet from ground level ＋ removal of all secondary branches, （3） Detopping of primary branches at 8 feet from the ground level ＋ removal of all secondary branches at 2 feet from the base of primary branches, （4） Detopping of primary branches at 8 feet from the ground level ＋ removal of all secondary branches at 1 feet from the base of primary branches, （5） Light judicious pruning ＋ Detopping of plant canopy of at 8 feet from the ground level, （6） No pruning （control）. Results of three consecutive years of investigation revealed that light judicious pruning of thin, overlapping, criss-crossed, dead, unproductive and looping branches gave highest fruit yield in all the three years and resulted 64.4 percent yield increment over control when average of three years was considered. Severe pruning of primary and secondary branches caused drastic reduction of yield for two consecutive years after pruning. Judicious pruning helped to produce better sizeable and quality fruits.
文摘A dynamic experimental apparatus to measure the instantaneous velocity and pressure in the multi-bypass pulse tube refrigerator (MPTR) was designed and constructed. Some theortant experimental results of the instantaneous measurements of the velocity and the pressure in the MPTR with two-bypass tubes during actual operation are presented. The effects of the middle-bypass version on the dynamic pressure and mass flow rate at the cold end of the pulse tube are evaluated from experimental measurements.DC-flow phenomena are observed in this MPTR. The reasons of the multi-bypass version improved the performance of pulse tube refrigerator are given.
基金Project (No. 51176164) supported by the National Natural Science Foundation of China
文摘In this paper, a novel system using direct contact heat transfer between air and water solution was proposed to generate ice slurry. The heat transfer process and the system performance were studied; energy efficiency coefficients of 0.038, 0.053, and 0.064 were obtained using different solutions. An empirical relationship between the volumetric heat transfer coefficient U v and the main parameters was obtained by fitting the experimental data. The U v calculated from the empirical formula agreed with the experimental U v quite well with a relative error of less than 15%. Based on the empirical formula, a laboratory-scale direct contact ice slurry generator was then constructed, with practical application in mind. If the air flow rate is fixed at 200 m 3 /h, the ice production rate will be 0.091 kg/min. The experimental results also showed that the cold energy consumption of the air compressor accounted for more than half of the total amount. To improve the system energy efficiency coefficient, it is necessary to increase the air pipes insulation and the solution's thermal capacity, and also it is appropriate to utilize the free cold energy of liquefied natural gas (LNG).
文摘This paper reports the experiments of evaporation study in 6 mm inner copper diamter tubes us-ing HFC-134a, HCFC-22 and CFC-12 as working nuid. The results show that the evaporation heat transfer coefficient increases with the decreasing of inner diameter of tubes. A new concept of non-dimensional tube diameter U is proposed in this paper for correction of the influence of the tube diameter on the evaporation heat transfer coefficient. And further, a convnient empirical correction mehod is pented.
