AIM:To describe a modified technique for placement of a tracheobronchial self-expanding plastic stent(SEPS) in patients with benign refractory hypopharyngeal strictures in order to improve dysphagia and allow strictur...AIM:To describe a modified technique for placement of a tracheobronchial self-expanding plastic stent(SEPS) in patients with benign refractory hypopharyngeal strictures in order to improve dysphagia and allow stricture remodeling.METHODS:A case series of four consecutive patients with complex hypopharyngeal strictures after combinedtherapy for laryngeal cancer,previously submitted to multiple sessions of dilation without lasting improvement,is presented.All patients underwent placement of a small diameter and unflared tracheobronchial SEPS.Main outcome measurements were improvement of dysphagia and avoiding of repeated dilation.RESULTS:The modified introducer system allowed an easy and technically successful deployment of the tracheobronchial Polyflex stent through the stricture.All four patients developed complications related to stent placement.Two patients had stent migration(one proximal and one distal),two patients developed phanryngocutaneous fistulas and all patients with stents in situ for more than 8 wk had hyperplastic tissue growth at the upper end of the stent.Stricture recurrence was observed at 4 wk follow-up after stent removal in all patients CONCLUSION:Although technically feasible,placement of a tracheobronchial SEPS is associated with a high risk of complications.Small diameter stents must be kept in place for longer than 3 mo to allow adequate time for stricture remodeling.展开更多
The point under study is the first of such a nature. This paper investigates the management of innovation adopted by the European leader in sports equipment: Decathlon (Oxylane Group). In recent years, vertical int...The point under study is the first of such a nature. This paper investigates the management of innovation adopted by the European leader in sports equipment: Decathlon (Oxylane Group). In recent years, vertical integration push and innovation have secured the company's leadership and success in a number of sports markets throughout Europe. It now has 909 stores located globally. Oxylane Group designs, manufactures, and sells sports products for sports people worldwide. It offers fitness, dance, gymnastics, and combat sports products; bicycles, equipment, and accessories; team sports products; nautical and water sports products (surf sports, diving, sailing, and kayaking products); swimming products; mountain sports products (for hiking, mountain trailing, camping, skiing, and snow shoe hiking); skiing and snowboarding products (for snowboarders and skiers); and climbing and mountaineering products. The company is now a direct challenger for world sports leaders. Since the end of the 1990's, Decathlon different sports brands have not taken a unique and rational path to success. The company has built insights about its customers, identified and evaluated unique market opportunities, and prepared a bold game plan to seize them. By doing so, Decathlon has developed a stream of winning products. The process of new business creation generally splits into two parts: an upstream process (sensing and creating opportunities) and a downstream process (converting the selected opportunities into successful products). Most businesses have a formal process implemented to manage the downstream part. Few that people know of have set up an equivalent process like Oxylane and Decathlon to sense and create new opportunities in the sports equipment industry. The aim of the paper is to examine how the brand has developed two of its successful product: the tent two seconds and the wetsuit "Inergy". These two products are chosen as examples to understand how the upstream process articulate with the downstream one.展开更多
The college textbooks Treasury management is an important part of the whole teaching management. It is not only to thousands of materials properly stored reserves, but also in the warehouse operation planning, strengt...The college textbooks Treasury management is an important part of the whole teaching management. It is not only to thousands of materials properly stored reserves, but also in the warehouse operation planning, strengthen treasury management is important to ensure the stability of school teaching order.展开更多
文摘AIM:To describe a modified technique for placement of a tracheobronchial self-expanding plastic stent(SEPS) in patients with benign refractory hypopharyngeal strictures in order to improve dysphagia and allow stricture remodeling.METHODS:A case series of four consecutive patients with complex hypopharyngeal strictures after combinedtherapy for laryngeal cancer,previously submitted to multiple sessions of dilation without lasting improvement,is presented.All patients underwent placement of a small diameter and unflared tracheobronchial SEPS.Main outcome measurements were improvement of dysphagia and avoiding of repeated dilation.RESULTS:The modified introducer system allowed an easy and technically successful deployment of the tracheobronchial Polyflex stent through the stricture.All four patients developed complications related to stent placement.Two patients had stent migration(one proximal and one distal),two patients developed phanryngocutaneous fistulas and all patients with stents in situ for more than 8 wk had hyperplastic tissue growth at the upper end of the stent.Stricture recurrence was observed at 4 wk follow-up after stent removal in all patients CONCLUSION:Although technically feasible,placement of a tracheobronchial SEPS is associated with a high risk of complications.Small diameter stents must be kept in place for longer than 3 mo to allow adequate time for stricture remodeling.
文摘The point under study is the first of such a nature. This paper investigates the management of innovation adopted by the European leader in sports equipment: Decathlon (Oxylane Group). In recent years, vertical integration push and innovation have secured the company's leadership and success in a number of sports markets throughout Europe. It now has 909 stores located globally. Oxylane Group designs, manufactures, and sells sports products for sports people worldwide. It offers fitness, dance, gymnastics, and combat sports products; bicycles, equipment, and accessories; team sports products; nautical and water sports products (surf sports, diving, sailing, and kayaking products); swimming products; mountain sports products (for hiking, mountain trailing, camping, skiing, and snow shoe hiking); skiing and snowboarding products (for snowboarders and skiers); and climbing and mountaineering products. The company is now a direct challenger for world sports leaders. Since the end of the 1990's, Decathlon different sports brands have not taken a unique and rational path to success. The company has built insights about its customers, identified and evaluated unique market opportunities, and prepared a bold game plan to seize them. By doing so, Decathlon has developed a stream of winning products. The process of new business creation generally splits into two parts: an upstream process (sensing and creating opportunities) and a downstream process (converting the selected opportunities into successful products). Most businesses have a formal process implemented to manage the downstream part. Few that people know of have set up an equivalent process like Oxylane and Decathlon to sense and create new opportunities in the sports equipment industry. The aim of the paper is to examine how the brand has developed two of its successful product: the tent two seconds and the wetsuit "Inergy". These two products are chosen as examples to understand how the upstream process articulate with the downstream one.
文摘The college textbooks Treasury management is an important part of the whole teaching management. It is not only to thousands of materials properly stored reserves, but also in the warehouse operation planning, strengthen treasury management is important to ensure the stability of school teaching order.