Our results show that in liver microsomes from erythromycin,acetylspiramycin and dexamethsone pretreated rats,the rate of praziquantel( PQT)disappearence was increased as compared with control rat When microsomes fro...Our results show that in liver microsomes from erythromycin,acetylspiramycin and dexamethsone pretreated rats,the rate of praziquantel( PQT)disappearence was increased as compared with control rat When microsomes from erythromycin-treated rats were exposed to PQT in the presence of potassium ferricyanide which broke down the cytochrome P-450 Fe(Ⅱ)-metabolite complexes and restored the functional cytochrome P-450,PQT metabolism was further increased. Acetylspiramycin did not form the complexes, so potassium ferricyanide showed no effect on the PQT metabolism in microsomes from acetylspiramycin-treated rats. Triacetyloleandomycin,a specific inhibitor of cytochrome P-450ⅢAI, inhibited PQT metabolism by 53% in liver microsomes from dexamethasone-treated rats.These results indicate the cytochrome P-450ⅢA seems to be involved in metabolism of PQT in rat liver microsomes.展开更多
Supercritical antisolvent (SAS) process is a recently developed technology to produce micro- and nano particles. This paper presents a continuous apparatus to conduct experiment of SAS process. With the apparatus, the...Supercritical antisolvent (SAS) process is a recently developed technology to produce micro- and nano particles. This paper presents a continuous apparatus to conduct experiment of SAS process. With the apparatus, the effects of pressure, temperature and flow ratio of CO2 to the solution on the shape and size of particles are studied for the quercetin-ethanol-CO2 system. Spherical quercetin microparticles with diameters ranging form 1 μm to 6μm can be obtained while ethanol is used as organic solvent. The most effective fact on the shape and size of particles is pressure, the next is temperature and the last is the flow ratio of CO2 to solution.展开更多
An improved FGS (Fine Granular Scalability) coding method is proposed in this letter, which is based on human visual characteristics. This method adjusts FGS coding frame rate according to the evaluation of video sequ...An improved FGS (Fine Granular Scalability) coding method is proposed in this letter, which is based on human visual characteristics. This method adjusts FGS coding frame rate according to the evaluation of video sequences so as to improve the coding efficiency and subject perceived quality of reconstructed images. Finally, a fine granular joint source channel coding is proposed based on the source coding method, which not only utilizes the network resources efficiently, but guarantees the reliable transmission of video information.展开更多
This paper reports a microfluidic method of continuous separation of marine algae and particles by DC dielectrophoresis. The locally non-uniform electric field is generated by an insulating PDMS triangle hurdle fabric...This paper reports a microfluidic method of continuous separation of marine algae and particles by DC dielectrophoresis. The locally non-uniform electric field is generated by an insulating PDMS triangle hurdle fabricated within a PDMS microchannel. Both the particles and algae are subject to negative DEP forces at the hurdle where the gradient of local electric-field strength is the strongest. The DEP force acting on the particle or the algae depends on particles' or algae's volume, shape and dielectric properties. Thus the moving particles and algae will be repelled to different streamlines when passing the hurdle. In this way, combined with the electroosmotic flow, continuous separation of algae of two different sizes, and continuous separation of polystyrene particles and algae with similar volume but different shape were achieved. This first demonstration of DC DEP separation of polystyrene particles and algae with similar sizes illustrates the great influence of dielectric properties on particle separation and potentials for sample pretreatment.展开更多
We discuss the X(5568)particle recently announced by the D0 Collaboration.Several types of models were proposed to explain this structure in the literature.As pointed out by Burns and Swanson(ar Xiv:1603.04366),none o...We discuss the X(5568)particle recently announced by the D0 Collaboration.Several types of models were proposed to explain this structure in the literature.As pointed out by Burns and Swanson(ar Xiv:1603.04366),none of them provides a satisfactory description of the observation.We provide additional arguments using general properties of QCD,and conclude that the observation of the X(5568),if confirmed,poses serious challenges to our understanding of nonperturbative QCD.展开更多
文摘Our results show that in liver microsomes from erythromycin,acetylspiramycin and dexamethsone pretreated rats,the rate of praziquantel( PQT)disappearence was increased as compared with control rat When microsomes from erythromycin-treated rats were exposed to PQT in the presence of potassium ferricyanide which broke down the cytochrome P-450 Fe(Ⅱ)-metabolite complexes and restored the functional cytochrome P-450,PQT metabolism was further increased. Acetylspiramycin did not form the complexes, so potassium ferricyanide showed no effect on the PQT metabolism in microsomes from acetylspiramycin-treated rats. Triacetyloleandomycin,a specific inhibitor of cytochrome P-450ⅢAI, inhibited PQT metabolism by 53% in liver microsomes from dexamethasone-treated rats.These results indicate the cytochrome P-450ⅢA seems to be involved in metabolism of PQT in rat liver microsomes.
文摘Supercritical antisolvent (SAS) process is a recently developed technology to produce micro- and nano particles. This paper presents a continuous apparatus to conduct experiment of SAS process. With the apparatus, the effects of pressure, temperature and flow ratio of CO2 to the solution on the shape and size of particles are studied for the quercetin-ethanol-CO2 system. Spherical quercetin microparticles with diameters ranging form 1 μm to 6μm can be obtained while ethanol is used as organic solvent. The most effective fact on the shape and size of particles is pressure, the next is temperature and the last is the flow ratio of CO2 to solution.
基金Supported by National Natural Science Foundation of China (No.90104013) and 863 project(2001AA121061)
文摘An improved FGS (Fine Granular Scalability) coding method is proposed in this letter, which is based on human visual characteristics. This method adjusts FGS coding frame rate according to the evaluation of video sequences so as to improve the coding efficiency and subject perceived quality of reconstructed images. Finally, a fine granular joint source channel coding is proposed based on the source coding method, which not only utilizes the network resources efficiently, but guarantees the reliable transmission of video information.
基金support from the Fundamental Research Funds for the Central Universities (2011QN105, 2011ZD014)the Dalian Science and Technology Foundation (2011J21DW005) to SONG YongXin+2 种基金National Science & Technology Pillar Program of China in 2010 (2010BAC68B02)Liaoning Science & Technology Program (2007405010) to SUN YeQingthe Natural Sciences and Engineering Research Council of Canada through a research grant to LI DongQing
文摘This paper reports a microfluidic method of continuous separation of marine algae and particles by DC dielectrophoresis. The locally non-uniform electric field is generated by an insulating PDMS triangle hurdle fabricated within a PDMS microchannel. Both the particles and algae are subject to negative DEP forces at the hurdle where the gradient of local electric-field strength is the strongest. The DEP force acting on the particle or the algae depends on particles' or algae's volume, shape and dielectric properties. Thus the moving particles and algae will be repelled to different streamlines when passing the hurdle. In this way, combined with the electroosmotic flow, continuous separation of algae of two different sizes, and continuous separation of polystyrene particles and algae with similar volume but different shape were achieved. This first demonstration of DC DEP separation of polystyrene particles and algae with similar sizes illustrates the great influence of dielectric properties on particle separation and potentials for sample pretreatment.
基金Supported by DFG and National Natural Science Foundation of China Through Funds Provided to the Sino-German CRC 110"Symmetriesthe Emergence of Structure in QCD"(National Natural Science Foundation of China under Grant No.11261130311)+1 种基金the Thousand Talents Plan for Young Professionalsand the Chinese Academy of Sciences President’s International Fellowship Initiative under Grant No.2015VMA076
文摘We discuss the X(5568)particle recently announced by the D0 Collaboration.Several types of models were proposed to explain this structure in the literature.As pointed out by Burns and Swanson(ar Xiv:1603.04366),none of them provides a satisfactory description of the observation.We provide additional arguments using general properties of QCD,and conclude that the observation of the X(5568),if confirmed,poses serious challenges to our understanding of nonperturbative QCD.
