来氟米特联合康痹汤治疗类风湿关节炎临床观察

目的:观察来氟米特联合康痹汤治疗类风湿性关节炎的临床疗效。方法:将52例患者分为治疗组和对照组。治疗组(口服来氟米特和康痹汤)27例,对照组(口服来氟米特)25例,两组均治疗6个月。观察治疗前后临床症状、实验室指标变化和不良反应。结果:两组临床症状、实验室指标均较治疗前有明显改善(P<0.05或P<0.01),治疗组优于对照组(P<0.05或P<0.01);治疗组、对照组不良反应发生率分别为3.7%、20%,两组比较有显著性差异(P<0.05)。结论:来氟米特联合康痹汤治疗类风湿关节炎的临床疗效显著优于单独使用来氟米特,且具有毒副作用小的优点。

幼年型类风湿关节炎患儿外周血中Th_1与Th_2比例失衡探讨

目的:探讨JRA患儿外周血中T辅助细胞(Th_1/Th_2)分布状态。方法:应用三色荧光标记法流式细胞仪检测25例JRA患儿外周血中Th_1和Th_2的百分率,以8位择期小手术儿童作对照。结果:显示JRA患儿外周血中Th_2细胞较正常人少,但Th_1数目则与正常人无异。结论:Th_2细胞减少,可能是JRA致病原理之一。

类风湿性关节炎的肺胸膜表现56例临床分析

目的了解并分析类风湿性关节炎(rheumatoidarthritis,RA)对呼吸系统的影响。方法选择符合诊断标准的RA患者110例,对有肺部表现的56例根据其一般临床表现,呼吸系统症状和体征、胸部X线检查和肺功能检查进行分析。结果110例中56例有明显肺部表现,占50·9%。呼吸系统症状和体征主要为干咳、胸痛、呼吸困难、水泡音。可发生肺间质纤维化,肺功能损害为限制性通气障碍、弥散功能障碍和小气道通气障碍。胸部X线检查表现为肺间质纤维化、胸腔积液、胸膜肥厚、肺结节、肺纹理增多和肺部渗出性病变。结论RA对呼吸系统的影响较常见,应引起重视。

藏医药浴治疗类风湿关节炎

类风湿性关节炎又称类风湿（RA），是一种病因尚未明了的慢性全身性炎症性疾病，以慢性、对称性、多滑膜关节炎和关节外病变为主要临床表现，属于自身免疫炎性疾病。该病好发于手、腕、足等小关节，反复发作，呈对称分布。早期有关节红肿热痛和功能障碍即关节酸痛，麻木，屈伸不利，晚期关节可出现不同程度的僵硬畸形，并伴有骨和骨骼肌的萎缩，极易致残。

金诺芬治疗类风湿关节炎双盲对照28例

选择28例类风湿关节炎(RA)作双盲临床试验,全部完成24wk疗程。金诺芬组18例,3mg,qd×2wk,增至3mg,bid共24wk。在晨僵、握力、关节疼痛数和(或)压痛数、关节肿胀数、血沉和C-反应蛋白指标均比安慰剂组10例改善明显。临床缓解和显效率在金诺芬组占89％,在安慰剂组仅40％。提示金诺芬为一有效、安全和方便的改善RA病情药物。

Clinical observation of warm needling moxibustion for rheumatoid arthritis

Objective： To observe the clinical efficacy of warm needling moxibustion at points on the back in treating rheumatoid arthritis （RA）. Methods： Sixty RA patients were randomized into two groups by the random number table, 30 in each group. The observation group was intervened by warm needling moxibustion at the points from the Governor Vessel on the back and Jiaji （EX-B 2） points, while the control group was by regular acupuncture. Results： After intervention, the morning stiffness, joint pain index, joint swelling index and erythrocyte sedimentation rate （ESR） were significantly improved in both groups （P〈0.01）; the inter-group difference was also statistically significant （P〈0.05）. The total effective rate was 93.3% in the observation group versus 76.6% in the control group, and the difference was statistically significant （P〈0.01）. Conclusion： Warm needling moxibustion at points from the Governor Vessel on the back and Jiaji （EX-B 2） points can produce a higher efficacy than regular acupuncture in treating RA.

Warm Needling Method on Rheumatoid Arthritis

Objective： to observe the clinical effects of warm needling on rheumatoid arthritis. Methods： Patients with rheumatoid were treated with warming needling on the major acupoints of Guanyuan（CV 4）, Qihai（CV 6）, Zusanli（ST 36）, Ganshu（BL 18）, Shenshu（BL 23） and Pishu（BL 20）, in combination with local acupoints and acupoints on the related meridians, meanwhile, other patients were treated with single needling as control. The patients＇ joint pain, tenderness, swelling, dysfunction index, gripping force, morning stiffness, walking time of 20 meters, rheumatoid factor, erythrocyte sedimentation rate, C response protein, IgG, IgA, and IgM were measured before and after treatments. Results： Warm needling could improve the rheumatoid arthritis patients＇ symptoms, and had an effective rate of 86.2%, while the single needling had an effective rate of 57.1%（P〈0.01）. And the therapeutic effects were related to the disease duration and condition. Conclusion： Warm needling has a better clinical effects on rheumatoid arthritis than the single needling, with obvious functions of anti-inflammation, relieving pain and regulating immunity.