软粘土劈裂注浆微观结构的分形特征

利用扫描电镜(SEM)和数字图像技术研究软粘上劈裂注浆过程中微观结构孔隙的变化,采用室内试验和分形理论相结合的方法研究注浆前后孔隙结构的korcak分形特征,结合IPP量测数据得出了描述孔隙结构Korcak分维数.结果表明,劈裂注浆前后的孔隙结构具有明显的分形特征,korcak分维数在0.896～1.552之间,水泥-水玻璃浆体不仅具有细化粗孔的效果,而且孔隙的特征也有了明显的改善.分维数的数值大小反映了软粘土劈裂注浆过程中的孔隙度变化,孔隙度愈小,分维数愈大,分维数与孔隙度、孔隙数量之间存在较为显著的线性回归关系.

Modeling air gun signatures in marine seismic exploration considering multiple physical factors

Based on analyzing the limit of Ziolkowski＇s bubble oscillation formulation,a new model with various physical factors is established to simulate air gun signatures fo marine seismic exploration.The practical effects of physical factors,such as heat transfe across the bubble wall,air gun port throttling,vertical rise of the bubble,fluid viscosity,and the existence of the air gun body were all taken into account in the new model.Compared with Ziolkowski＇s model,the signatures simulated by the new model,with small peak amplitude and rapid decay of bubble oscillation,are more consistent with actual signatures The experiment analysis indicates：（1）gun port throttling controls the peak amplitude of ai gun pulse;（2）since the hydrostatic pressure decreases when the bubble rises,the bubble oscillation period changes;（3）heat transfer and fluid viscosity are the main factors tha explain the bubble oscillation damping.

浅析混凝土中钢筋锈蚀对混凝土结构的影响

简要阐述混凝土结构耐久性研究的意义,介绍混凝土中钢筋锈蚀的机理,并分别介绍钢筋锈蚀对其基本力学性能的影响、钢筋锈蚀对混凝土和钢筋之间粘结性能的影响和钢筋锈蚀对混凝土构件承载力的影响三个方面的研究现状。

脱模剂MK529/11在轮胎生产中的应用

针对轮胎硫化脱模时存在的轮胎粘上模造成的肩部薄胶边、钢丝圈弯曲等问题,研究不同脱模剂在轮胎生产中的应用效果。结果表明:脱模剂MK529/11和进口脱模剂B为水性产品,无胶料隔离问题,对轮胎外观无不良影响,且为中性产品,不腐蚀模具;脱模剂MK529/11每班基本喷涂1次,可解决轮胎粘上模问题,肩部胶边可与轮胎一起脱下,胎肩垫伤缺陷率降低了57.44%。

彩泥变变变——小刺猬

1选一个自己喜欢的颜色的彩泥,搓成圆球,再把一端捏尖。2用剪刀剪出刺。3捏两片白彩泥,上面粘上黑彩泥,做成眼睛。再用黑彩泥捏出鼻子。4把它们组装起来,可爱的小刺猬就出现在你的面前啦。

绳编立体玩具 (封底说明)

材料: 各种颜色皱纹纸、剪刀、胶水、废纸、旧布、球、纸卷等。 制作: 将皱纹纸剪成1厘米宽的带子。三条带子打一个结,用编辫子的方法编成绳子,利用这种绳子便可做各种玩具。

Erythropoietin -induced proliferation of gastric mucosal cells

AIM： To analyze the localization of erythropoietin receptor on gastric specimens and characterize the effects of erythropoietin on the normal gastric epithelial proliferation using a porcine gastric epithelial cell culture model. METHODS： Erythropoietin receptor was detected by RT-PCR, Western blotting and immunohistochermistry. Growth stimulation effects of erythropoietin on cultured gastric mucosal cells were determined by ELISA using bromodeoxyuridine （BrdU）. RESULTS： Erythropoietin receptor was detected on cultured porcine gastric mucosal epithelial cells. Erythropoietin receptor was also detected histochemically at the base of gastric mucosal epithelium. BrdU assay demonstrated a dose-dependent increase in growth potential of cultured porcine gastric mucosal epithelial cells by administration of erythropoietin, as well as these effects were inhibited by administration of antierythropoietin antibody （P〈 0.01）. CONCLUSION： These findings indicate that erythropoietin has a potential to proliferate gastric mucosal epithelium via erythropoietin receptor.

Hydrodynamic Behavior of a Single Bubble Rising in Viscous Liquids

The rising behavior of single bubbles has been investigated in six systems with different viscosity and Morton number(Mo) from 3.21×10-11 to 163. Bubbles with maximum equivalent diameter of up to 16 mm were investigated. The bubble Reynolds number(Re) ranged from 0.02 to 1200 covering 3 regimes in which two func-tions are obtained relating the drag coefficient,CD,with Re and Mo. It has been found that in the high Reynolds number regime the drag coefficient increases until the Reynolds number of about 1200. The classic expression of Jamialahmadi(1994) is improved and extended to high viscosity liquids. A new relationship for the aspect ratio of deformed bubbles in terms of Re,the Etvs number and Mo,applicable to a wide range of system properties,espe-cially in high viscosity liquids,is also suggested.

Diagnosis of gastric epithelial neoplasia:Dilemma for Korean pathologists

The histopathological diagnosis of gastric mucosal biopsy and endoscopic mucosal resection/endoscopic submucosal dissection specimens is important,but the diagnostic criteria,terminology,and grading system are not the same in the East and West.A structurally invasive focus is necessary to diagnose carcinoma for most Western pathologists,but Japanese pathologists make a diagnosis of cancer based on severe dysplastic cytologic atypia irrespective of the presence of invasion.Although the Vienna classification was introduced to reduce diagnostic discrepancies,it has been difficult to adopt due to different concepts for gastric epithelial neoplastic lesions.Korean pathologists experience much difficulty making a diagnosis because we are influenced by Japanese pathologists as well as Western medicine.Japan is geographically close to Korea,and academic exchanges are active.Additionally,Korean doctors are familiar with Western style medical terminology.As a result,the terminology,definitions,and diagnostic criteria for gastric intraepithelial neoplasia are very heterogeneous in Korea.To solve this problem,the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists has made an effort and has suggested guidelines for differential diagnosis:(1) a diagnosis of carcinoma is based on invasion;(2) the most important characteristic of low grade dysplasia is the architectural pattern such as regular distribution of crypts without severe branching,budding,or marked glandular crowding;(3) if nuclear pseudostratification occupies more than the basal half of the cryptal cells in three or more adjacent crypts,the lesion is considered high grade dysplasia;(4) if severe cytologic atypia is present,careful inspection for invasive foci is necessary,because the risk for invasion is very high;and(5) other structural or nuclear atypia should be evaluated to make a final decision such as cribriform pattern,papillae,ridges,vesicular nuclei,high nuclear/cytoplasmic ratio,loss of nuclear polarity,thick and irregular nuclear membrane,and nucleoli.

Non-sequential narrow band imaging for targeted biopsy and monitoring of gastric intestinal metaplasia

AIM： To evaluate the efficacy of non-sequential narrow band imaging （NBI） for a better recognition of gastric intestinal metaplasia （GIM）. METHODS： Previously diagnosed GIM patients underwent targeted biopsy from areas with and without GIM, as indicated by NBI, twice at an interval of 1 year. The authors compared the endoscopic criteria such as light blue crest （LBC）, villous pattern （VP）, and large long crest （LLC） with standard histology. The results from two surveillance endoscopies were compared with histology results for sensitivity, specificity, positive predic-tive value （PPV）, negative predictive value （NPV）, and likelihood ratio of positive test （LR＋）. The number of early gastric cancer cases detected was also reported. RESULTS： NBI targeted biopsy was performed in 38 and 26 patients during the first and second surveillance endoscopies, respectively. There were 2 early gastric cancers detected in the first endoscopy. No cancer was detected from the second study. Surgical and endoscopic resections were successfully performed in each patient. Sensitivity, specificity, PPV, NPV, and LR＋ of all 3 endoscopic criteria during the first/second surveillances were 78.8%/91.3%, 82.5%/89.1%, 72.8%/77.8%, 86.8%/96.1, and 4.51/8.4, respectively. LBC provided the highest LR＋ over VP and LLC. CONCLUSION： Nonequential NBI is useful for GIM targeted biopsy. LBC provides the most sensitive reading. However, the optimal duration between two surveillances requires further study.

Numerical Study of Viscous Wave-Making Resistance of Ship Navigation in Still Water

The prediction of a ship＇s resistance especially the viscous wave-making resistance is an important issue in CFD applications. In this paper, the resistances of six ships from hull 1 to hull 6 with different hull forms advancing in still water are numerically studied using the solver naoe-FOAM-SJTU, which was developed based on the open source code package OpenFOAM. Different components of the resistances are computed and compared while considering two speed conditions （12 kn and 16 kn）. The resistance of hull 3 is the smallest while that of hull 5 is the largest at the same speed. The results show hull 3 is a good reference for the design of similar ships, which can provide some valuable guidelines for hull form optimization.

Starch Modifications to Improve the Paste Stabilities Both in Phase and Viscosity for Warp Sizing

An attempt has been made to improve the paste stabilities both in viscosity of a hot starch paste and in phase of a starch-polyvinyl alcohol blend paste for warp sizing. The phase stability was evaluated in terms of the initial demixing time, and the volume percentage of polyvinyl alcohol separated. It was found that starch cross-linking is harmful to the phase stability of a starch-polyvinyl alcohol blend paste no matter what a type of polyvinyl alcohol is used, although the cross-linking is an effective technique for stabilizing the viscosity of a hot starch paste. The separation rate and extent all increase with the increase in the cross-linking degree of starch. However, this defect can be eliminated through introducing quaternary ammonium groups into crosslinked starch molecules. Evident effect can be achieved when the degree of substitution is as less as 0.021. Generally, increase in the DS reduces the separation rate and extent, and thereby raising the phase stability. Moreover, the effects of both starch content and PVA type on the separation are also considered. Cationization after starch cross-linking shows improved stabilities both in viscosity and phase.

Characterization of hepatic progenitors from human fetal liver during second trimester

AIM： To enrich hepatic progenitors using epithelial cell adhesion molecule （EpCAM） as a marker from human fetal liver and investigate the expression of human leukocyte antigen （HLA） and their markers associated with hepatic progenitor cells. METHODS： EpCAM ＋ve cells were isolated using magnetic cell sorting （MACS） from human fetuses （n = 10） at 15-25 wk gestation. Expression of markers for hepatic progenitors such as albumin, alpha-fetoprotein （AFP）, CD29 （integrin ~1）, CD49f （integrin c^6） and CD90 （Thy 1） was studied by using flow cytometry, immunocytochemistry and RT-PCR; HLA class Ⅰ （A, B, C） and class Ⅱ （DR） expression was studied by flow cytometry only. RESULTS： FACS analysis indicated that EpCAM ＋ve cells were positive for CD29, CD49f, CD90, CD34, HLA class I, albumin and AFP but negative for HLA class Ⅱ （DR） and CD45. RT PCR showed that EpCAM ＋ve cells expressed liver epithelial markers （CK18）, biliary specific marker （CK19） and hepatic markers （albumin, AFP）. On immunocytochemical staining, EpCAM ＋ve cells were shown positive signals for CK18 and albumin. CONCLUSION： Our study suggests that these EpCAM ＋ve cells can be used as hepatic progenitors for cell transplantation with a minimum risk of alloreactivity and these cells may serve as a potential source for enrichment of hepatic progenitor.

Antagomir Dependent MicroRNA-205 Reduction Enhances Adhesion Ability of Human Corneal Epithelial Keratinocytes

Objective To investigate the effect of microRNA-205 reduction by antagomirs on adhesion ability of normal human corneal epithelial keratinocytes(NHCEKs).Methods Antagomir-205,complementary and inhibitory to microRNA-205,was used to suppress endogenous microRNA-205 in NHCEKs.The adhesion ability of treated NHCEKs was then assessed by cell adhesion assay.Immunoblot and immunohistochemistry were conducted to determine the level of two focal adhesion-related proteins,focal adhesion kinase(FAK) and paxillin(Pax).Phalloidin staining was performed to measure the level of filamentous actin in antagomir-treated NHCEKs.Results Antagomir-205 markedly reduced the level of microRNA-205 in NHCEKs and significantly enhanced adhesion ability of NHCEKs(P<0.01).Further protein analysis validated that inhibition of mi-croRNA-205 increased the number of phosphorylated FAK and phosphorylated Pax,and decreased filamen-tous actin.Conclusion Our findings suggest that microRNA-205 has down-regulating effect on cell motility in NHCEKs.

Adherence and invasion of mouse-adapted H pylori in different epithelial cell lines

AIM： To assess the adhesion and invasion abilities of different mouse adapted H py/or/strains in different cell lines in vitro and investigate their effects on the virulence factors cagA and vacA. METHODS： The adherence and invasion abilities of different N pylori strains in different epithelial cell lines were examined by the gentamycin protection assay. The null mutants of cagA and vacA were processed by direct PCR mutation method. The morphologic changes of different cell lines after N pylori attachment were examined by microscopy. RESULTS： The densities of adherence to and invasion into cells in vitro were different from those in the mouse infection experiments. 88-3887 strain could invade and adhere to cells stronger than SS1 and X47. All tested strains had better adhering and invasive abilities in SCG-7901 cell. CagA and vacA minus mutants had the same invasion and adherent abilities as their wild types. In all strains and cell lines tested, only AGS cell had the significant hummingbird phenotype after inoculation with the 88-3887 wild-type. CONCLUSION： Both the host cells and the bacteria play important parts in the invasion and adhesion abilities of Hpylori. CagA and VacA are not related to the ability of invasion and adhesion of Hpylori in different cell lines in vitro.

Modification of HDPE filling with pelagic clay

In order to improve the properties of HDPE, the authors used the method of suspended diffusion for purification the pelagic clay, used silane coupling agent to increase its organic activation, and prepared the composites of organic pelagic clay/HDPE by inching them in different conditions. The affections of process conditions and quantity of pelagic clay to the properties of composites were analyzed by testing their mechanical properties, thermo stability and barrier properties. According to test the structure of composites, it is indicated that pelagic clay has good compatibility with HDPE. The result shows that the pelagic clay can improve mechanical properties, thermo stability and barrier properties of HDPE properties effectively.

Individual detection significances of small breast epithelial mucin (SBEM) and human mammaglobin (hMAM) expressions in peripheral blood of breast cancer patients

Objective： The aim of the study was to explore the individual detection significances of small breast epithelial mucin （SBEM） and human mammaglobin （hMAM） in peripheral blood （PB） of breast cancer patients. Methods： SBEM and hMAM expressions in PB samples of 109 primary breast cancer patients were detected by flow cytometry （FCM） and RT- PCR. Relationship between the biomarkers＇ expression and prognostic parameters were analyzed. Results： SBEM and hMAM expressions in PB of breast cancer patients were much higher than those of healthy donors and other cancer patients. SBEM and hMAM expressed in 53.2% （50/94） and 39.4% （37/94） cases at stages I-III and expressed in 73.3% （11/15） and 46.7% （7/15） cases at stage IV respectively. SBEM and hMAM mRNA were only detected in PB samples of breast cancer patients, while no expression of them was found in that of healthy donors and other cancer patients. Conclusion： hMAM mRNA detection maybe helpful to predict hematogenous micrometastasis in ER-positive, well-differentiated breast cancers and SBEM mRNA detection maybe helpful to predict hematogenous micrometastasis in ER-negative, poody-differentiated breast cancers.

The study on the Psychological motivation of Costs Stickiness --Empirical Evidence from China

This paper studies Whether the managerial overconfidence have any impact on the Cost management （Characterized by the degree of the Costs Stickiness ） .Using the ample of the A-share listed companies between 2007-2011 in China, We document that SG＆A cost stickiness decreases in the degree of overconfidence. The further studies show the negative relation is more significant in the state-owned listed companies,which proved our speculation that the manager will cut expenses avoiding significant decline in performance when the sales decline in the state-owned listed company.