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结肠肿瘤性病变单克隆抗体MC_3的表达及其与异型粘液分泌的关系
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作者 黄卓垣 张亚历 +1 位作者 张素娟 邱红明 《癌症》 SCIE CAS CSCD 北大核心 1991年第4期302-304,共3页
本文应用抗人结肠癌单克隆抗体MC_3对32例结肠腺病性息肉。11例绒毛状腺病,18例结肠腺瘤伴不典型增生和36例结肠腺癌组织进行了PAP免疫组织化学染色,并同时采用醛复红—阿辛蓝(AF/AB)复合染色法,观察了结肠癌异型粘液分泌与MC_3表达的... 本文应用抗人结肠癌单克隆抗体MC_3对32例结肠腺病性息肉。11例绒毛状腺病,18例结肠腺瘤伴不典型增生和36例结肠腺癌组织进行了PAP免疫组织化学染色,并同时采用醛复红—阿辛蓝(AF/AB)复合染色法,观察了结肠癌异型粘液分泌与MC_3表达的关系。结果表明,MC_3主要为结肠肿瘤的标记癌组织MC_3表达有三种类型即腺腔型腔缘型和细胞型、前两型表达亦见于结肠腺瘤,其中腺瘸性息肉和绒毛状腺瘤MC_3表达的阳性率存在差异。本文还观察到癌组织MC_3表达的类型与强度癌细胞分泌非硫酸粘液有一定关系。 本文提示MC_3与结肠肿瘤细胞的分泌有关,并可将其用于结肠癌细胞生物学特性研究及结肠肿瘤的辅助诊断。 展开更多
关键词 结肠肿瘤 粘液反应 单克隆抗体
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Study on seismic response control of a single-tower self-anchored suspension bridge with elastic-plastic steel damper 被引量:12
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作者 WANG Hao ZHOU Rui +2 位作者 ZONG ZhouHong WANG Chen LI AiQun 《Science China(Technological Sciences)》 SCIE EI CAS 2012年第6期1496-1502,共7页
Elastic-plastic steel damper(EPSD) is a new device controlling seismic responses.The mechanical principle of EPSD was presented and a comparison was conducted between the theoretical formulas and finite element(FE) si... Elastic-plastic steel damper(EPSD) is a new device controlling seismic responses.The mechanical principle of EPSD was presented and a comparison was conducted between the theoretical formulas and finite element(FE) simulation of damper units.The verified force-displacement hysteretic curve of the damper system was obtained with reference to tests.The Nanjing Jiangxinzhou Bridge(NJB) was subsequently taken as the case to investigate the seismic response control effect of EPSDs on single-tower self-anchored suspension bridges.A 3-dimensional FE model of the bridge was established in ANSYS and the dynamic and static analyses of the bridge were conducted,the control effect of EPSDs under different seismic waves was further investigated through nonlinear time-history analysis based on the validated model.Results showed that both the simplified theoretical and FE simulation methods can preferable reflect the mechanical performance of EPSD,and that seismic responses of NJB with EPSDs are better than those with elastic connection device or fluid viscous damper.However,the control effect of EPSDs is influenced by seismic wave characteristics. 展开更多
关键词 elastic-plastic steel damper single-tower self-anchored suspension bridge FE model validation nonlinear time-historyanalysis seismic response control
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