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急性脑梗死患者颈动脉粥样硬化斑超声声像图特征回顾分析 被引量:2
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作者 蒋丽娜 刘洪 +4 位作者 张露月 孟青 李嘉舟 程阔菊 郑东 《四川文理学院学报》 2020年第2期91-94,共4页
回顾2019年6月-2020年2月我院住院部神经内科急性脑梗死患者,且有完整的颈动脉超声检查报告资料83例,对其颈动脉粥样硬化斑的形态和类型特征进行回顾分析总结.发现83例急性脑梗死患者中,合并颈动脉粥样硬化斑者76例(约占91.56%),其中稳... 回顾2019年6月-2020年2月我院住院部神经内科急性脑梗死患者,且有完整的颈动脉超声检查报告资料83例,对其颈动脉粥样硬化斑的形态和类型特征进行回顾分析总结.发现83例急性脑梗死患者中,合并颈动脉粥样硬化斑者76例(约占91.56%),其中稳定性斑块17例(约占22.37%),不稳定性斑块59例(约占77.63%).急性脑梗死的发生与颈动脉粥样硬化斑有密切的相关性,不稳定性斑块、低回声斑、混合回声斑易于引起脑梗死. 展开更多
关键词 脑梗死 粥样硬化斑 超声 声像图特征
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冠状动脉粥样硬化斑块破裂与炎症 被引量:2
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作者 付海霞 蒋锡嘉 +1 位作者 许家 李建军 《医学综述》 2001年第3期142-143,共2页
关键词 冠状动脉粥样硬化斑破裂 炎症 治疗
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进展性冠状动脉粥样硬化斑块在心肌梗塞发生中的意义
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作者 马正中 谢春光 +6 位作者 刘冬戈 周季 孙肇武 满开泉 吴淑敏 刘志宏 孙仁俊 《心肺血管学报》 1989年第2期102-104,共3页
作者对41例有Ⅲ级以上狭窄的冠状动脉粥样斑块进行认真的形态学观察和分析,结果发现在心肌梗组(18例)平均每例斑块总数为21.4,其中45.9%为进展性斑块;而15例非冠心病死亡病例平均每例斑块总数为10,其中只有14%为进展性斑块(P<0.001)... 作者对41例有Ⅲ级以上狭窄的冠状动脉粥样斑块进行认真的形态学观察和分析,结果发现在心肌梗组(18例)平均每例斑块总数为21.4,其中45.9%为进展性斑块;而15例非冠心病死亡病例平均每例斑块总数为10,其中只有14%为进展性斑块(P<0.001)。冠心病猝死组则界于两组之间,分别为20.1和34.2%。作者认为当冠状动脉Ⅲ级以上斑块数量多、并有较多的进展性斑块时易于发生心肌梗塞和猝死。 展开更多
关键词 心肌梗塞 冠状动脉 粥样硬化斑
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定向冠状动脉粥样硬化斑块切除术——冠心病治疗新技术
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《吉林医学情报》 1992年第4期64-64,共1页
关键词 冠心病 定向冠脉粥样硬化斑 切除
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多层螺旋CT显像对氟伐他汀逆转冠状动脉粥样斑块的评价
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作者 赵碧琼 李莉 +3 位作者 田美荣 邓晓蕴 姜玉茹 李欣 《中国老年学杂志》 CAS CSCD 北大核心 2005年第7期849-850,共2页
关键词 多层螺旋CT 氟伐他汀 冠状动脉粥样硬化斑
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脉冲超声多普勒对颈动脉粥样硬化病变的诊断意义... 被引量:6
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作者 邹艳秋 吴逊 《中华神经精神科杂志》 CSCD 1991年第6期370-372,8,共4页
关键词 脑血管疾病 劲动脉 粥样硬化斑
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肾病综合征合并股动脉血栓1例报道并文献复习 被引量:1
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作者 董杨 张祥贵 汤杰印 《医学信息(医学与计算机应用)》 2014年第24期640-640,共1页
1临床资料 患者男性,72岁,因颜面部和双下肢浮肿,泡沫尿1个月,于2012年3月在当地医院查:尿蛋白3+,予以保肾药物治疗,症状无明显缓解,3个月后浮肿加重复查血清白蛋白13.58 g/L,24h尿蛋白2.25 g,拟诊:肾病综合征,予强的松60 mg/d顿服等治... 1临床资料 患者男性,72岁,因颜面部和双下肢浮肿,泡沫尿1个月,于2012年3月在当地医院查:尿蛋白3+,予以保肾药物治疗,症状无明显缓解,3个月后浮肿加重复查血清白蛋白13.58 g/L,24h尿蛋白2.25 g,拟诊:肾病综合征,予强的松60 mg/d顿服等治疗,7 d后患者出现右下肢疼痛伴寒冷,次日疼痛加重,肤色发紫,来我院外科就诊。查体:右下肢膝以下为青紫色伴皮温明显下降,腘动脉、足动脉波动消失,左下肢无异常,血管超声示:右侧股动脉粥样硬化斑块形成狭窄,CT示右侧股动脉中远段附壁血栓,即行右股动脉切开取栓术,术中见股动脉多处动脉硬化斑,不能剥出,未予处理,取出三段长共约14 cm的血栓,术后予尿激酶3000 U/d溶栓,华法令2.5 mg,qd抗凝等治疗,为进一步治疗肾病综合征转入肾内科。既往无特殊病史,12年前发现高血压,脑血栓病血液流变学示血液粘稠度增高血小板聚集性增加;血压为198/160 mmHg左右,经硝苯地平,倍他乐克等可控140/80 mmHg左右,家族中无血栓形成等类似病史。 展开更多
关键词 肾病 股动脉血栓 药物治疗 双下肢浮肿 粥样硬化斑 血小板聚集性 尿蛋白 血液粘稠度 血液流变学 血清白蛋白 血压 血栓形成 血管超声 硝苯地平 下肢疼痛 脑血栓病 临床资料 患者 附壁血栓 倍他乐克
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彩色多普勒超声检查诊断脑梗塞的价值
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作者 张静 张伟民 《常州实用医学》 2014年第3期154-156,共3页
目的观察彩色多普勒超声检查诊断脑梗塞的价值。方法应用彩色多普勒超声检查脑梗塞患者(观察组)、健康体检者(对照组)的颈动脉内膜-中层厚度(IMT)与粥样硬化斑的发生率。结果IMT增厚和动脉粥样斑块发生率观察组分别为73.8%和72... 目的观察彩色多普勒超声检查诊断脑梗塞的价值。方法应用彩色多普勒超声检查脑梗塞患者(观察组)、健康体检者(对照组)的颈动脉内膜-中层厚度(IMT)与粥样硬化斑的发生率。结果IMT增厚和动脉粥样斑块发生率观察组分别为73.8%和72.5%,对照组分别11.3%和15.O%,观察组显著高于对照组,差异有统计学意义。结论彩色多普勒超声检查颈动脉内膜中层厚度(IMT)与粥样硬化斑的发生率能为诊断脑梗塞提供重要的价值。 展开更多
关键词 彩色多普勒超声 颈动脉 内膜-中层厚度 粥样硬化斑 脑梗塞 价值
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Beneficial clinical effects of grape seed proanthocyanidin extract on the progression of carotid atherosclerotic plaques 被引量:5
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作者 Ai-Hong CAO Jian WANG +2 位作者 Hai-Qing GAO Ping ZHANG Jie QIU 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2015年第4期417-423,共7页
Background Atherosclerotic plaques indicate the occurrence of ischemia events and it is a difficult task for clinical physicians. Grape seed proanthocyanidin extract (GSPE) has been reported to exert an antiatheroge... Background Atherosclerotic plaques indicate the occurrence of ischemia events and it is a difficult task for clinical physicians. Grape seed proanthocyanidin extract (GSPE) has been reported to exert an antiatherogenic effect by inducing regression of atherosclerotic plaques in animal experimental studies. In this study, the antiatherogenic effect of GSPE has been investigated in clinical use. Methods Consecu- tive 287 patients diagnosed with asymptomatic carotid plaques or abnormal plaque free carotid intima-media thickness (CIMT) were ran- domly assigned to the GSPE group (n = 146) or control group (n = 141). The patients in the GSPE group received GSPE 200 mg per day orally, while patients in the control group were only enrolled in a lifestyle intervention program. Carotid ultrasound examination was per- formed at baseline and 6, 12, 24 months during follow-up. Mean maximum CIMT (MMCIMT), plaque score, echogenicity of plaques and ischemic vascular events were recorded. Results As anticipated, after treatment, GSPE resulted in significant reduction in MMCIMT pro- gression (4.2% decrease after six months, 4.9% decrease after 12 months and 5.8% decrease after 24 months) and plaque score (10.9% de- crease after six months, 24.1% decrease after 12 months and 33.1% decrease after 24 months) for the primary outcome, while MMCIMT and plaque score were stable and even increased with the time going on in control group. The number of plaques and unstable plaques also de- creased after treatment of GSPE. Furthermore, the carotid plaque can disappear after treatment with GSPE. The incidence rate for transitory ischemic attack (TIA), arterial revascularization procedure, and hospital readmission for unstable angina in GSPE group were statistically significant lower (P = 0.02, 0.08, 0.002, respectively) compared with the control group. Conclusions GSPE inhibited the progression of MMCIMT and reduced carotid plaque size in GSPE treated patients, and with extended treatment, the superior efficacy on MMCIMT and carotid plaque occurred. Furthermore, the GSPE group showed lower rates of clinical vascular events. 展开更多
关键词 ATHEROSCLEROSIS Carotid plaque Grape seed proanthocyanidin extract
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Relationship between Framingham risk score and subclinical atherosclerosis in carotid plaques: an in vivo study using multi-contrast MRI 被引量:5
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作者 Feiyu Li Xiaoying Wang 《Science China(Life Sciences)》 SCIE CAS CSCD 2017年第1期23-27,共5页
The assessment and management of early-stage atherosclerosis are important for the prevention of cardiovascular disease(CVD).In this study,we used multi-contrast magnetic resonance imaging(MRI) to investigate the caro... The assessment and management of early-stage atherosclerosis are important for the prevention of cardiovascular disease(CVD).In this study,we used multi-contrast magnetic resonance imaging(MRI) to investigate the carotid plaque feature in asymptomatic,at-risk subjects;we also evaluated the correlation between MRI findings and Framingham risk score(FRS).One hundred sixty-six asymptomatic individuals with risk factors for CVD underwent multi-contrast MRI.After the arterial morphology and plaque components were outlined,the differences in carotid plaque burden among the various risk categories were analyzed.The FRS analysis showed that high-risk individuals had thicker vessel wall and higher plaque lipid content than did low risk participants.A substantial proportion of advanced carotid plaques occurred in low and intermediate-risk groups.Multi-contrast MRI may provide incremental value to the FRS in managing asymptomatic at-risk population. 展开更多
关键词 ATHEROSCLEROSIS carotid artery magnetic resonance imaging Framingham risk score
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Enhanced External Counterpulsation Treatment Inhibitting Advanced Atherosclerotic Plaque Progression by Augmenting the Plaque Wall Stress: An in vivo FSI Study Based on Animal Experiment 被引量:1
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作者 DU Jian-hang HUANG Liang +4 位作者 WU Gui-fu ZHENG Zhen-sheng FENG Ming-zhe DAI Gang WU Fu-jun 《Chinese Journal of Biomedical Engineering(English Edition)》 CSCD 2016年第1期1-11,共11页
Enhance extemal counterpulsation (ECP) procedure has exhbited itself to be an effective therapy for the m anagem entof ischem ic card iovascu lar diseases, However, considering that EECP significantly increases the... Enhance extemal counterpulsation (ECP) procedure has exhbited itself to be an effective therapy for the m anagem entof ischem ic card iovascu lar diseases, However, considering that EECP significantly increases the acute diastolic pressure, whether it will intervene in the chronic progression of advanced plaque causing great concern in clilical applkation, but yet rein ains elusive presently. In the current paper, a flu id-structure interface (FSI) num erical model of artery with p iaque corn ponent w as developed based on in vivo hem odynam ic m easurem entperfotm ed h a porcine model, to caku late the m echanical stresses of the plaque before and during EECP, and h lum to assess the potential effects of long-term EECP treatm ent on plaque progression. The resu Its show that E E C P augm ented the wall shear stress (WSS) and plaque w all stress (PWS) over the card lac cycles, aswell as the spacial oscillatory of W SS (WSSG ). Durhg EECP treatm ent, the PW S level respectively raised 6.82% and 6.07% in two simulation cases. The currentpilot study suggests that E E C P treatm entre ay p lay a positive effect on inh biting the conthued plaque progression by hcreashg the PW S level over the card iac cycles. Meanwhile, the plaque morphology should be taken into consideration while m aking patient- specific plan for Ion g- term E E C P treatment in clinic. 展开更多
关键词 atherosc lerosis placlue progression enhanced extemal counterpulsation (EECP) flow-structure in teraction (FSI)
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