We describe a 74-year-old man with a colonic metastatic squamous cell carcinoma (SCC) from the lung. His chest X-ray revealed an abnormal shadow in the right upper lobe. Computed tomography (CT) of the chest demonstra...We describe a 74-year-old man with a colonic metastatic squamous cell carcinoma (SCC) from the lung. His chest X-ray revealed an abnormal shadow in the right upper lobe. Computed tomography (CT) of the chest demonstrated a large lung tumor in the right upper lobe obstructing the right upper bronchus. Bronchoscopy revealed an easy-bleeding tumor in the right upper bronchus that was diagnosed as poorly differentiated squamous cell lung carcinoma. He underwent colonoscopy because he had a positive fecal occult blood test. Colonoscopy revealed a large protruding lesion with central ulceration in the descending colon. Histological examination of the biopsy specimen obtained from the colonic lesion revealed SCC. The lesion was diagnosed as metastatic colonic SCC. He had no abdominal symptoms. He underwent chemotherapy with an infusion of cisplatin 130 mg i.v. day 1, and docetaxel hydrate 100 mg i.v. day 1, repeated every 4 wk, followed by 4 courses of chemotherapy. The primary lesion shrank by less than 10% and was judged to be "Partial Response" (PR) after 3 courses of treatment. The patient still lived 23 wk after the diagnosis of metastatic colonic SCC. Colonic metastasis of primary SCC of the lung is rare.展开更多
Lebanese marine water is exposed to multi-point source contaminants. Risk assessment associated with deteriorative water quality profile is not only affected by the disposed quantities of specific contaminant, but als...Lebanese marine water is exposed to multi-point source contaminants. Risk assessment associated with deteriorative water quality profile is not only affected by the disposed quantities of specific contaminant, but also its chemical speciated forms. The objective of this study is to quantify the Lebanese chemical marine water profile. Sea water samples were collected based on GIS map. The chemical water quality was assessed by measuring the macro water parameters and potential existing metals. The microbiological profile of water was evaluated by fecal coliform. Results showed contamination by fecal coliform and high levels of toxic metals. However, the actual projected impact of the detected metals on human health were assessed using geochemical models ＂FREEQCE＂ and ＂Mineq＋＂ that predict the metal species forms, mainly, the free aqua-metal ion, most toxic form. Thus, these results necessitate the proposal of integrated intervention plans for the protection of this marine source and consistent with international treaties.展开更多
文摘We describe a 74-year-old man with a colonic metastatic squamous cell carcinoma (SCC) from the lung. His chest X-ray revealed an abnormal shadow in the right upper lobe. Computed tomography (CT) of the chest demonstrated a large lung tumor in the right upper lobe obstructing the right upper bronchus. Bronchoscopy revealed an easy-bleeding tumor in the right upper bronchus that was diagnosed as poorly differentiated squamous cell lung carcinoma. He underwent colonoscopy because he had a positive fecal occult blood test. Colonoscopy revealed a large protruding lesion with central ulceration in the descending colon. Histological examination of the biopsy specimen obtained from the colonic lesion revealed SCC. The lesion was diagnosed as metastatic colonic SCC. He had no abdominal symptoms. He underwent chemotherapy with an infusion of cisplatin 130 mg i.v. day 1, and docetaxel hydrate 100 mg i.v. day 1, repeated every 4 wk, followed by 4 courses of chemotherapy. The primary lesion shrank by less than 10% and was judged to be "Partial Response" (PR) after 3 courses of treatment. The patient still lived 23 wk after the diagnosis of metastatic colonic SCC. Colonic metastasis of primary SCC of the lung is rare.
文摘Lebanese marine water is exposed to multi-point source contaminants. Risk assessment associated with deteriorative water quality profile is not only affected by the disposed quantities of specific contaminant, but also its chemical speciated forms. The objective of this study is to quantify the Lebanese chemical marine water profile. Sea water samples were collected based on GIS map. The chemical water quality was assessed by measuring the macro water parameters and potential existing metals. The microbiological profile of water was evaluated by fecal coliform. Results showed contamination by fecal coliform and high levels of toxic metals. However, the actual projected impact of the detected metals on human health were assessed using geochemical models ＂FREEQCE＂ and ＂Mineq＋＂ that predict the metal species forms, mainly, the free aqua-metal ion, most toxic form. Thus, these results necessitate the proposal of integrated intervention plans for the protection of this marine source and consistent with international treaties.
