期刊文献+
共找到4篇文章
< 1 >
每页显示 20 50 100
黄精改善中年房劳肾精亏虚大鼠免疫功能紊乱的作用研究
1
作者 俞静静 杜宇忠 +6 位作者 苏洁 颜美秋 胡雪灵 潘斌辉 牛壮伟 陈素红 吕圭源 《浙江中医药大学学报》 CAS 2024年第8期895-904,共10页
[目的]研究黄精对中年房劳肾精亏虚模型大鼠免疫功能紊乱的调节作用。[方法]采用“中年雄鼠+雌雄同笼”方法制备中年房劳肾精亏虚大鼠模型,模拟中年男性因房劳致肾精亏虚引起的免疫功能紊乱状态。实验期间测定大鼠脾脏系数;苏木精-伊红(... [目的]研究黄精对中年房劳肾精亏虚模型大鼠免疫功能紊乱的调节作用。[方法]采用“中年雄鼠+雌雄同笼”方法制备中年房劳肾精亏虚大鼠模型,模拟中年男性因房劳致肾精亏虚引起的免疫功能紊乱状态。实验期间测定大鼠脾脏系数;苏木精-伊红(hematoxylin-eosin,HE)染色观察脾组织形态学变化;测定骨髓中性粒细胞和淋巴细胞占比,外周血淋巴细胞数量及其占比和中性粒细胞占比;脾淋巴细胞增殖试验检测脾脏淋巴细胞增殖能力;流式细胞术测定脾组织T淋巴细胞亚群占比;原位末端转移酶标记(terminal-deoxynucleoitidyl transferase mediated nick end labeling,TUNEL)检测脾组织细胞凋亡情况;免疫印迹检测脾组织与增殖相关蛋白磷酸化磷脂酰肌醇3-激酶(phospho-phosphatidylinositol 3-kinase,p-PI3K)、磷酸化蛋白激酶B(phospho-ptotein kinase B,p-AKT)和与凋亡相关蛋白B淋巴细胞瘤-2(B-cell lymphoma-2,Bcl-2)、Bcl-2相关X(Bcl-2 associated X,Bax)蛋白表达。[结结果]黄精可降低中年房劳肾精亏虚模型大鼠骨髓和外周血中性粒细胞占比,升高骨髓淋巴细胞占比,升高外周血淋巴细胞数量及其占比,降低脾组织T淋巴细胞(CD4^(+)/CD8^(+))比值,提高脾组织T淋巴细胞增殖能力,减少脾组织内的细胞凋亡,升高脾组织中与增殖相关蛋白p-PI3K和p-AKT的表达。[结论]黄精通过影响T淋巴细胞及其亚群占比,改善中年大鼠因肾精亏虚引起的免疫功能紊乱,其机制可能与调控脾组织与增殖相关蛋白PI3K/AKT的表达有关。 展开更多
关键词 中年房亏虚模型 免疫功能紊乱 T淋巴细胞 增殖 凋亡 PI3K/AKT
下载PDF
种公畜配种过度引起的两种疾病
2
作者 冀贞阳 《养殖技术顾问》 2002年第6期7-7,共1页
关键词 种公畜 配种过度 精劳 五更泻 症状 治疗
下载PDF
Mechanical behaviors of cross roller bearings with raceway roundness error 被引量:3
3
作者 HUANG Jian LI Chao-yang CHEN Bing-kui 《Journal of Central South University》 SCIE EI CAS CSCD 2021年第7期2091-2104,共14页
Taking the raceway roundness error into account,mechanical characteristics of cross roller bearings(CRBs)were investigated.A static analysis model of CRBs considering the raceway roundness error was established.Based ... Taking the raceway roundness error into account,mechanical characteristics of cross roller bearings(CRBs)were investigated.A static analysis model of CRBs considering the raceway roundness error was established.Based on this model,the rotational accuracy and load distribution of CRBs under constraints of geometry and external loads were derived.The fatigue life of CRBs with roundness error was calculated by applying Palmgren-Miner linear cumulative damage theory.The influence of inner and outer raceway roundness error on the performance of the CRBs,such as rotational accuracy,load distribution,and fatigue life,was studied through the analysis of examples.The results indicate that the influence of roundness error on the rotating inner raceway is more significant than that of roundness error on the nonrotating outer raceway.The roundness error on the rotating inner raceway always degrades the performance of CRBs.However,a proper roundness error on the nonrotating outer raceway can reduce the loads acting on the rollers and thus improve the fatigue life of CRBs.The effect of the roundness error amplitude on the bearing performance is ordinal,whereas the effect of the roundness order on the bearing performance is not in order. 展开更多
关键词 cross roller bearings roundness error load distribution rotational accuracy fatigue life
下载PDF
Spectral Analysis of Blood Pressure Variability as a Quantitative Indicator of Driving Fatigue
4
作者 李增勇 焦昆 +1 位作者 陈铭 王成焘 《Journal of Donghua University(English Edition)》 EI CAS 2004年第1期85-88,共4页
The quantitative detector of driver fatigue presents appropriate warnings and helps to prevent traffic accidents.The aim of this study was to quantifiably evaluate driver mental fatigue using the power spectral analys... The quantitative detector of driver fatigue presents appropriate warnings and helps to prevent traffic accidents.The aim of this study was to quantifiably evaluate driver mental fatigue using the power spectral analysis of the blood pressure variability (BPV) and subjective evaluation. In this experiment twenty healthy male subjects were required to perform a driving simulator task for 3-hours. The physiological variables for evaluating driver mental fatigue were spectral values of blood pressure variability (BPV)including very low frequency (VLF), low frequency (LF),high frequency (HF). As a result, LF, HF and LF/HF showed high correlations with driver mental fatigue but not found in VLF. The findings represent a possible utility of BPV spectral analysis in quantitatively evaluating driver mental fatigue. 展开更多
关键词 Driving fatigue Blood pressure variability Driving simulator
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部