Tobacco-producing field should carry out research oriented by fined technology,fluent work procedure and satisfied effect,reinforce lean management promotion,optimize allocation of tobacco production technologies,empl...Tobacco-producing field should carry out research oriented by fined technology,fluent work procedure and satisfied effect,reinforce lean management promotion,optimize allocation of tobacco production technologies,employees and resources,and improve science and technology research and development in a premise of improving tobacco quality,stable tobacco texture,and increasing tobacco production profit,in order to highlight service function of cooperatives and advance sustainable development.展开更多
AIM:To characterize the inductive effects of isoflurane(ISO) on hepatic heme oxygenase-1(HO-1) in an animal model of hepatic steatosis.METHODS:Lean(LEAN) and obese(FAT) Zucker rats were randomized into 4 groups:1:LEAN...AIM:To characterize the inductive effects of isoflurane(ISO) on hepatic heme oxygenase-1(HO-1) in an animal model of hepatic steatosis.METHODS:Lean(LEAN) and obese(FAT) Zucker rats were randomized into 4 groups:1:LEAN + pentobarbital sodium(PEN);2:LEAN + ISO;3:FAT + PEN;4:FAT + ISO.The animals were mechanically ventilated for 6 h.In vitro analyses of liver tissue included determination of HO-1 mRNA and protein expression as well as measurement of HO enzyme activity and immunohistochemical analyses.RESULTS:Compared to PEN treatment,ISO administration profoundly induced hepatic HO-1 mRNA and protein expression and significantly increased HO enzyme activity in lean Zucker rats.In contrast,no difference in HO-1 gene expression was observed after ISO or PEN anesthesia in obese Zucker rats.CONCLUSION:The present study demonstrates that ISO is an inducer of hepatic HO-1 gene expression in non-steatotic organs but failed to upregulate HO-1 in steatotic livers.展开更多
The traditional prediction methods of element yield rate can be divided into experience method and data-driven method.But in practice,the experience formulae are found to work only under some specific conditions,and t...The traditional prediction methods of element yield rate can be divided into experience method and data-driven method.But in practice,the experience formulae are found to work only under some specific conditions,and the sample data that are used to establish data-driven models are always insufficient.Aiming at this problem,a combined method of genetic algorithm(GA) and adaptive neuro-fuzzy inference system(ANFIS) is proposed and applied to element yield rate prediction in ladle furnace(LF).In order to get rid of the over reliance upon data in data-driven method and act as a supplement of inadequate samples,smelting experience is integrated into prediction model as fuzzy empirical rules by using the improved ANFIS method.For facilitating the combination of fuzzy rules,feature construction method based on GA is used to reduce input dimension,and the selection operation in GA is improved to speed up the convergence rate and to avoid trapping into local optima.The experimental and practical testing results show that the proposed method is more accurate than other prediction methods.展开更多
文摘Tobacco-producing field should carry out research oriented by fined technology,fluent work procedure and satisfied effect,reinforce lean management promotion,optimize allocation of tobacco production technologies,employees and resources,and improve science and technology research and development in a premise of improving tobacco quality,stable tobacco texture,and increasing tobacco production profit,in order to highlight service function of cooperatives and advance sustainable development.
文摘AIM:To characterize the inductive effects of isoflurane(ISO) on hepatic heme oxygenase-1(HO-1) in an animal model of hepatic steatosis.METHODS:Lean(LEAN) and obese(FAT) Zucker rats were randomized into 4 groups:1:LEAN + pentobarbital sodium(PEN);2:LEAN + ISO;3:FAT + PEN;4:FAT + ISO.The animals were mechanically ventilated for 6 h.In vitro analyses of liver tissue included determination of HO-1 mRNA and protein expression as well as measurement of HO enzyme activity and immunohistochemical analyses.RESULTS:Compared to PEN treatment,ISO administration profoundly induced hepatic HO-1 mRNA and protein expression and significantly increased HO enzyme activity in lean Zucker rats.In contrast,no difference in HO-1 gene expression was observed after ISO or PEN anesthesia in obese Zucker rats.CONCLUSION:The present study demonstrates that ISO is an inducer of hepatic HO-1 gene expression in non-steatotic organs but failed to upregulate HO-1 in steatotic livers.
基金Projects(2007AA041401,2007AA04Z194) supported by the National High Technology Research and Development Program of China
文摘The traditional prediction methods of element yield rate can be divided into experience method and data-driven method.But in practice,the experience formulae are found to work only under some specific conditions,and the sample data that are used to establish data-driven models are always insufficient.Aiming at this problem,a combined method of genetic algorithm(GA) and adaptive neuro-fuzzy inference system(ANFIS) is proposed and applied to element yield rate prediction in ladle furnace(LF).In order to get rid of the over reliance upon data in data-driven method and act as a supplement of inadequate samples,smelting experience is integrated into prediction model as fuzzy empirical rules by using the improved ANFIS method.For facilitating the combination of fuzzy rules,feature construction method based on GA is used to reduce input dimension,and the selection operation in GA is improved to speed up the convergence rate and to avoid trapping into local optima.The experimental and practical testing results show that the proposed method is more accurate than other prediction methods.
