An aero-engine is a typically repairable and complex system and its maintenance level has a close relationship with the maintenance cost. The inaccurate measurement for the maintenance level of an aero-engine can indu...An aero-engine is a typically repairable and complex system and its maintenance level has a close relationship with the maintenance cost. The inaccurate measurement for the maintenance level of an aero-engine can induce higher overhaul maintenance costs. Variable precision rough set （VPRS） theory is used to determine the maintenance level of an aero-engine. According to the relationship between condition information and performance parameters of aero-engine modules, decision rules are established for reflecting the real condition of an aeroengine when its maintenance level needs to be determined. Finally, the CF6 engine is used as an example to illustrate the method to be effective.展开更多
In order to improve the performance of the attribute reduction algorithm to deal with the noisy and uncertain large data, a novel co-evolutionary cloud-based attribute ensemble multi-agent reduction（CCAEMR） algorith...In order to improve the performance of the attribute reduction algorithm to deal with the noisy and uncertain large data, a novel co-evolutionary cloud-based attribute ensemble multi-agent reduction（CCAEMR） algorithm is proposed.First, a co-evolutionary cloud framework is designed under the M apReduce mechanism to divide the entire population into different co-evolutionary subpopulations with a self-adaptive scale. Meanwhile, these subpopulations will share their rewards to accelerate attribute reduction implementation.Secondly, a multi-agent ensemble strategy of co-evolutionary elitist optimization is constructed to ensure that subpopulations can exploit any correlation and interdependency between interacting attribute subsets with reinforcing noise tolerance.Hence, these agents are kept within the stable elitist region to achieve the optimal profit. The experimental results show that the proposed CCAEMR algorithm has better efficiency and feasibility to solve large-scale and uncertain dataset problems with complex noise.展开更多
For a special coupled Korteweg de Vries （KdV） system, its similarity solutions and reduction equations are obtained by the Clarkson and Kruskal＇s direct method. In addition, its new explicit soliton solutions and t...For a special coupled Korteweg de Vries （KdV） system, its similarity solutions and reduction equations are obtained by the Clarkson and Kruskal＇s direct method. In addition, its new explicit soliton solutions and traveling wave solutions are found by the deformation and mapping method.展开更多
Applying the Lie group method to the differential-difference equation, the Lie point symmetry of Blaszak- Marciniak four-field Lattice equation is obtained. Using the obtained symmetry, the similarity reduction equati...Applying the Lie group method to the differential-difference equation, the Lie point symmetry of Blaszak- Marciniak four-field Lattice equation is obtained. Using the obtained symmetry, the similarity reduction equations of Blaszak-Marciniak four-field Lattice equation are derived. Solving the reduction, we get the solution of Blaszak-Marciniak four-field Lattice equation which not only recovers one of the solutions obtained by Ma and Hu [J. Math. Phys. 40 （1999） 6071] but also has the singularity when we choose the arbitrary constants accurately.展开更多
AIMTo assess whether surrogate biomarkers of endotoxemia were correlated with the histological features of nonalcoholic fatty liver disease (NAFLD).METHODSOne hundred twenty-six NAFLD patients who had undergone percut...AIMTo assess whether surrogate biomarkers of endotoxemia were correlated with the histological features of nonalcoholic fatty liver disease (NAFLD).METHODSOne hundred twenty-six NAFLD patients who had undergone percutaneous liver biopsy were enrolled. Serum lipopolysaccharide (LPS)-binding protein (LBP) and anti-endotoxin core immunoglobulin G (EndoCab IgG) antibody concentrations at the time of liver biopsy were measured using the enzyme-linked immunosorbent assays to examine for relationships between biomarker levels and histological scores.RESULTSSerum LBP concentration was significantly increased in nonalcoholic steatohepatitis (NASH) patients as compared with nonalcoholic fatty liver (NAFL) subjects and was correlated with steatosis (r = 0.38, P < 0.0001) and ballooning scores (r = 0.23, P = 0.01), but not with the severity of lobular inflammation or fibrosis. Multivariate linear regression analysis revealed that LBP was associated with steatosis score and circulating C-reactive protein, aspartate aminotransferase, and fibrinogen levels. Serum EndoCab IgG concentration was comparable between NASH and NAFL patients. No meaningful correlations were detected between EndoCab IgG and histological findings.CONCLUSIONLBP/EndoCab IgG were not correlated with lobular inflammation or fibrosis. More accurate LPS biomarkers are required to stringently assess the contribution of endotoxemia to conventional NASH.展开更多
Using the machinery of Lie group analysis,the nonlinear system of coupled Burgers-type equations is studied.Using the infinitesimal generators in the optimal system of subalgebra of the said Lie algebras,it leads to t...Using the machinery of Lie group analysis,the nonlinear system of coupled Burgers-type equations is studied.Using the infinitesimal generators in the optimal system of subalgebra of the said Lie algebras,it leads to two nonequivalent similarity transformations by using it we obtain two reductions in the form of system of nonlinear ordinary differential equations.The search for solutions of these systems by using the G'/G-method has yielded certain exact solutions expressed by rational functions,hyperbolic functions,and trigonometric functions.Some figures are given to show the properties of the solutions.展开更多
Viral entry into the host is the earliest stage of infection in the viral life cycle in which attachment proteins play a key role. VP31(WSV340/WSSV396), an envelope protein of white spot syndrome virus(WSSV), contains...Viral entry into the host is the earliest stage of infection in the viral life cycle in which attachment proteins play a key role. VP31(WSV340/WSSV396), an envelope protein of white spot syndrome virus(WSSV), contains an Arg-Gly-Asp(RGD) peptide domain known as a cellular attachment site. At present, the process of VP31 interacting with shrimp host cells has not been explored. Therefore, the VP31 gene was cloned into p ET30a(+), expressed in Escherichia coli strain BL21 and purifi ed with immobilized metal ion affi nity chromatography. Four gill cellular proteins of shrimp( Fenneropenaeus c hinensis) were pulled down by an affi nity column coupled with recombinant VP31(r VP31), and the amino acid sequences were identifi ed with MALDI-TOF/TOF mass spectrometry. Hemocyanin, beta-actin, arginine kinase(AK), and an unknown protein were suggested as the putative VP31 receptor proteins. SDS-PAGE showed that AK is the predominant binding protein of VP31. An i n vitro binding activity experiment indicated that recombinant AK's(r AK) binding activity with r VP31 is comparable to that with the same amount of WSSV. These results suggested that AK, as a member of the phosphagen kinase family, plays a role in WSSV infection. This is the fi rst evidence showing that AK is a binding protein of VP31. Further studies on this topic will elucidate WSSV infection mechanism in the future.展开更多
文摘An aero-engine is a typically repairable and complex system and its maintenance level has a close relationship with the maintenance cost. The inaccurate measurement for the maintenance level of an aero-engine can induce higher overhaul maintenance costs. Variable precision rough set （VPRS） theory is used to determine the maintenance level of an aero-engine. According to the relationship between condition information and performance parameters of aero-engine modules, decision rules are established for reflecting the real condition of an aeroengine when its maintenance level needs to be determined. Finally, the CF6 engine is used as an example to illustrate the method to be effective.
基金The National Natural Science Foundation of China(No.61300167)the Open Project Program of State Key Laboratory for Novel Software Technology of Nanjing University(No.KFKT2015B17)+3 种基金the Natural Science Foundation of Jiangsu Province(No.BK20151274)Qing Lan Project of Jiangsu Provincethe Open Project Program of Key Laboratory of Intelligent Perception and Systems for High-Dimensional Information of Ministry of Education(No.JYB201606)the Program for Special Talent in Six Fields of Jiangsu Province(No.XYDXXJS-048)
文摘In order to improve the performance of the attribute reduction algorithm to deal with the noisy and uncertain large data, a novel co-evolutionary cloud-based attribute ensemble multi-agent reduction（CCAEMR） algorithm is proposed.First, a co-evolutionary cloud framework is designed under the M apReduce mechanism to divide the entire population into different co-evolutionary subpopulations with a self-adaptive scale. Meanwhile, these subpopulations will share their rewards to accelerate attribute reduction implementation.Secondly, a multi-agent ensemble strategy of co-evolutionary elitist optimization is constructed to ensure that subpopulations can exploit any correlation and interdependency between interacting attribute subsets with reinforcing noise tolerance.Hence, these agents are kept within the stable elitist region to achieve the optimal profit. The experimental results show that the proposed CCAEMR algorithm has better efficiency and feasibility to solve large-scale and uncertain dataset problems with complex noise.
基金Supported by Natural Science Foundations of Jiangxi Province under Grant Nos. 2008GZS0045 and 2009GZW0026
文摘For a special coupled Korteweg de Vries （KdV） system, its similarity solutions and reduction equations are obtained by the Clarkson and Kruskal＇s direct method. In addition, its new explicit soliton solutions and traveling wave solutions are found by the deformation and mapping method.
基金Supported by the National Natural Science Foundation of China under Grant No.10735030the National Natural Science Foundation of China under Grant No.90718041+1 种基金Shanghai Leading Academic Discipline Project under Grant No.B412Program for Changjiang Scholars and Innovative Research Team in University under Grant No.IRT0734
文摘Applying the Lie group method to the differential-difference equation, the Lie point symmetry of Blaszak- Marciniak four-field Lattice equation is obtained. Using the obtained symmetry, the similarity reduction equations of Blaszak-Marciniak four-field Lattice equation are derived. Solving the reduction, we get the solution of Blaszak-Marciniak four-field Lattice equation which not only recovers one of the solutions obtained by Ma and Hu [J. Math. Phys. 40 （1999） 6071] but also has the singularity when we choose the arbitrary constants accurately.
文摘AIMTo assess whether surrogate biomarkers of endotoxemia were correlated with the histological features of nonalcoholic fatty liver disease (NAFLD).METHODSOne hundred twenty-six NAFLD patients who had undergone percutaneous liver biopsy were enrolled. Serum lipopolysaccharide (LPS)-binding protein (LBP) and anti-endotoxin core immunoglobulin G (EndoCab IgG) antibody concentrations at the time of liver biopsy were measured using the enzyme-linked immunosorbent assays to examine for relationships between biomarker levels and histological scores.RESULTSSerum LBP concentration was significantly increased in nonalcoholic steatohepatitis (NASH) patients as compared with nonalcoholic fatty liver (NAFL) subjects and was correlated with steatosis (r = 0.38, P < 0.0001) and ballooning scores (r = 0.23, P = 0.01), but not with the severity of lobular inflammation or fibrosis. Multivariate linear regression analysis revealed that LBP was associated with steatosis score and circulating C-reactive protein, aspartate aminotransferase, and fibrinogen levels. Serum EndoCab IgG concentration was comparable between NASH and NAFL patients. No meaningful correlations were detected between EndoCab IgG and histological findings.CONCLUSIONLBP/EndoCab IgG were not correlated with lobular inflammation or fibrosis. More accurate LPS biomarkers are required to stringently assess the contribution of endotoxemia to conventional NASH.
文摘Using the machinery of Lie group analysis,the nonlinear system of coupled Burgers-type equations is studied.Using the infinitesimal generators in the optimal system of subalgebra of the said Lie algebras,it leads to two nonequivalent similarity transformations by using it we obtain two reductions in the form of system of nonlinear ordinary differential equations.The search for solutions of these systems by using the G'/G-method has yielded certain exact solutions expressed by rational functions,hyperbolic functions,and trigonometric functions.Some figures are given to show the properties of the solutions.
基金Supported by the National Science Foundation for Post-Doctoral Scientists of China(No.2013M541965)the International Postdoctoral Academic Exchange Program+2 种基金the Qingdao Postdoctoral Science Foundation Funded Projectthe Construction Program for“Taishan Scholarship”of Shandong Province of Chinathe Program for Chinese Outstanding Talents in Agricultural Scientific Research
文摘Viral entry into the host is the earliest stage of infection in the viral life cycle in which attachment proteins play a key role. VP31(WSV340/WSSV396), an envelope protein of white spot syndrome virus(WSSV), contains an Arg-Gly-Asp(RGD) peptide domain known as a cellular attachment site. At present, the process of VP31 interacting with shrimp host cells has not been explored. Therefore, the VP31 gene was cloned into p ET30a(+), expressed in Escherichia coli strain BL21 and purifi ed with immobilized metal ion affi nity chromatography. Four gill cellular proteins of shrimp( Fenneropenaeus c hinensis) were pulled down by an affi nity column coupled with recombinant VP31(r VP31), and the amino acid sequences were identifi ed with MALDI-TOF/TOF mass spectrometry. Hemocyanin, beta-actin, arginine kinase(AK), and an unknown protein were suggested as the putative VP31 receptor proteins. SDS-PAGE showed that AK is the predominant binding protein of VP31. An i n vitro binding activity experiment indicated that recombinant AK's(r AK) binding activity with r VP31 is comparable to that with the same amount of WSSV. These results suggested that AK, as a member of the phosphagen kinase family, plays a role in WSSV infection. This is the fi rst evidence showing that AK is a binding protein of VP31. Further studies on this topic will elucidate WSSV infection mechanism in the future.
