An optimization method of variant step length based on precision and two new concepts “variant step length based on precision” and “one dimensional search based on the sorting” are presented.They make the optimum...An optimization method of variant step length based on precision and two new concepts “variant step length based on precision” and “one dimensional search based on the sorting” are presented.They make the optimum design closely combined with precision of every design variable.In addition,the authors propose that for a multi peaked one dimensional search problem its optimum solution can be obtained by ordinary optimization methods only when the convexity or concavity of the objective function matches the step length determining the one dimensional search region and the method of finding the optimum step length factor.展开更多
BNCT is finally becoming ＂a new option against cancer＂. The difficulties for its development progress of that firstly is to improve the performance of boron compounds, secondly, it is the requirements of quantificat...BNCT is finally becoming ＂a new option against cancer＂. The difficulties for its development progress of that firstly is to improve the performance of boron compounds, secondly, it is the requirements of quantification and accuracy upon radiation dosimetry evaluation in clinical trials. Furthermore, that is long anticipation on hospital base neutron sources. It includes dedicated new NCT reactor, accelerator based neutron sources, and isotope source facilities. In ad- dition to reactors, so far, the technology of other types of sources for clinical trials is not yet completely proven. The In- Hospital Neutron lrradiator specially designed for NCT, based on the MNSR successfully developed by China, can be installed inside or near the hospital and operated directly by doctors. The Irradiator has two neutron beams for respective treatment of the shallow and deep tumors. It is expected to initiate operation in the end of this year. It would provide a safe, low cost, and effective treatment tool for the NCT routine application in near future.展开更多
文摘An optimization method of variant step length based on precision and two new concepts “variant step length based on precision” and “one dimensional search based on the sorting” are presented.They make the optimum design closely combined with precision of every design variable.In addition,the authors propose that for a multi peaked one dimensional search problem its optimum solution can be obtained by ordinary optimization methods only when the convexity or concavity of the objective function matches the step length determining the one dimensional search region and the method of finding the optimum step length factor.
文摘BNCT is finally becoming ＂a new option against cancer＂. The difficulties for its development progress of that firstly is to improve the performance of boron compounds, secondly, it is the requirements of quantification and accuracy upon radiation dosimetry evaluation in clinical trials. Furthermore, that is long anticipation on hospital base neutron sources. It includes dedicated new NCT reactor, accelerator based neutron sources, and isotope source facilities. In ad- dition to reactors, so far, the technology of other types of sources for clinical trials is not yet completely proven. The In- Hospital Neutron lrradiator specially designed for NCT, based on the MNSR successfully developed by China, can be installed inside or near the hospital and operated directly by doctors. The Irradiator has two neutron beams for respective treatment of the shallow and deep tumors. It is expected to initiate operation in the end of this year. It would provide a safe, low cost, and effective treatment tool for the NCT routine application in near future.
