期刊文献+
共找到6篇文章
< 1 >
每页显示 20 50 100
植物的伤卫信号分子——系统素
1
作者 刘福春 霍玉琴 《安徽农业科学》 CAS 2012年第7期3856-3857,共2页
综述了植物体内信号分子系统素(STM)的分子结构、生物活性、生理功能及其作用机理。
关键词 系统 系统素原 茉莉酸 伤卫信号分子
下载PDF
白细胞介素-33及其受体基质裂解素2信号通路在哮喘小鼠气道中的作用机制研究 被引量:2
2
作者 唐斌 李秋根 +3 位作者 李凡 尹祖安 王少华 黄丹 《实用医技杂志》 2020年第11期1429-1431,F0003,共4页
目的探讨白细胞介素(IL)-33及其受体基质裂解素2(ST2)信号通路在哮喘小鼠气道中的表达、激活及其相关机制。方法将36只小鼠随机分为正常对照组12只、哮喘未干预组12只和u0126干预组12只。建立卵清蛋白(OVA)致敏的小鼠哮喘模型。收集支... 目的探讨白细胞介素(IL)-33及其受体基质裂解素2(ST2)信号通路在哮喘小鼠气道中的表达、激活及其相关机制。方法将36只小鼠随机分为正常对照组12只、哮喘未干预组12只和u0126干预组12只。建立卵清蛋白(OVA)致敏的小鼠哮喘模型。收集支气管肺泡灌洗液(BALF),并对炎症细胞进行分类和计数。用酶联免疫吸附试验(ELISA)法检测BALF中IL-33和ST-2的水平。苏木精-伊红(HE)染色光镜下观察肺组织的病理变化。结果哮喘未干预组BALF中IL-33、ST2水平高于正常对照组(P<0.05),u0126干预组低于未干预组(P<0.05)。与正常对照组相比,未干预组小鼠肺组织病理学损伤及气道重塑明显加重,而u0126干预组小鼠肺组织病理学损伤及气道重塑较干预组缓解。结论IL-33/ST2信号通路参与哮喘小鼠气道炎症与气道重塑的分子机制。 展开更多
关键词 哮喘 气道重塑 促分裂素原活化蛋白(MAP)激酶信号系统
下载PDF
A Control Algorithm Derived from Immune Principle
3
作者 LIU Jian-hua YAN De-kun WU Li-bo 《Journal of China University of Mining and Technology》 2006年第3期344-348,共5页
Artificial immune systems (AIS) are biologically inspired problem solvers having been successfully applied in many fields. A controller was designed according to the interactive mechanism between immune molecules. Mul... Artificial immune systems (AIS) are biologically inspired problem solvers having been successfully applied in many fields. A controller was designed according to the interactive mechanism between immune molecules. Multiform antigens were constructed and corresponding antibodies designed. The concept of “antibiotic” is presented, whose features and injection time as well as construction method discussed. Based on biological immune mechanism, some fuzzy rules are summarized and used in constructing the controller. The result shows that this controller is simple in structure and can be easily computed, so it is suitable for real time control. The control variable can change adaptively according to the error and its change tendency. Therefore the controller is very flexible and can be directly used in controlling some nonlinear plants. To test the validity of the algorithm, two simulation examples are given, one is linear, and the other is nonlinear. The Simulation results indicate that the control performance of this algorithm is better than that of the conventional PID. 展开更多
关键词 artificial immune system CONTROL ANTIGEN ANTIBODY antibiotic
下载PDF
Influence of Isotope Substitution Helium Atom on Partial Cross Sections in He-HF Collisions
4
作者 YU Chun-Ri ZHANG Jie CHEN Li JIANG Gui-Sheng HUANG Guo-Dong 《Communications in Theoretical Physics》 SCIE CAS CSCD 2009年第11期924-928,共5页
Close-coupling equation and anisotropic potential developed in our previous research are applied to HE-SHe (4He, 6He, 8He,10He) collision system, and partial cross sections (PCSs) at the incident energy of 40 me V... Close-coupling equation and anisotropic potential developed in our previous research are applied to HE-SHe (4He, 6He, 8He,10He) collision system, and partial cross sections (PCSs) at the incident energy of 40 me V are calculated. By analyzing the differences of these PCSs, change rules of PCSs with the increase of partial wave number, and with the change of the mass of isotope substitution helium atom are obtained. The results show that excitation PCSs converge faster than elastic PCSs for collision energy and each of systems considered here. Also excitation PCSs converge more rapidly for high-excited states. Tail effect is present only in elastic scattering and low-excited states but not in high- excited states. With the increase of the mass of isotope substitution helium atom, converging speed of elastic, total inelastic, and state-to-state excitation PCS slows down, and the maxima of these PCSs undergoes a regular change. 展开更多
关键词 isotope substitution partial cross section close-coupling equation He-HF collision
下载PDF
血管紧张素原基因单倍型与原发性高血压的关联研究 被引量:7
5
作者 孔祥东 张思仲 +6 位作者 杨宇霞 郑克勤 童煜 施佳军 张克兰 苏智广 陈炜 《中华医学遗传学杂志》 EI CAS CSCD 2002年第6期488-490,共3页
目的 研究中国人群中血管紧张素原 (angiotensinogen,AGT)基因多态性及单倍型与原发性高血压的关系。方法 在 335例高血压患者与 196名血压正常人中采用 PCR-限制性酶切片段长度多态性法检测血管紧张素原基因的多态性 ,同时用最大期... 目的 研究中国人群中血管紧张素原 (angiotensinogen,AGT)基因多态性及单倍型与原发性高血压的关系。方法 在 335例高血压患者与 196名血压正常人中采用 PCR-限制性酶切片段长度多态性法检测血管紧张素原基因的多态性 ,同时用最大期望值方法进行两位点连锁不平衡和三位点的单倍型分析。结果 在 M2 35 T和 A- 2 0 C,M2 35 T和 A- 6 G,A- 2 0 C和 A- 6 G位点观察到了连锁不平衡 (P<10 - 4 )。病例 -对照检验显示 T2 35等位基因频率在高血压组中高于对照组 ,但所有单倍型频率分布在高血压组和正常对照组间差异无显著性。结论 受检人群中 AGT基因各单倍型与高血压未见关联 ,但 AGT基因T2 35位点可能是一种重要的高血压风险因子。 展开更多
关键词 肾素-血管紧张素原系统 连锁不平衡 单倍型 限制性片段长度多态性
原文传递
Compound-specific hydrogen isotopes of long-chain n-alkanes extracted from topsoil under a grassland ecosystem in northern China 被引量:4
6
作者 RAO ZhiGuo ZHU ZhaoYu +2 位作者 JIA GuoDong ZHANG Xiao WANG SuPing 《Science China Earth Sciences》 SCIE EI CAS 2011年第12期1902-1911,共10页
To investigate characteristics of H isotope variation in long-chain n-alkanes (δDn-alkanes) from higher plants in surface soils under a single ecosystem, 12 samples from a basalt regolith were randomly collected fr... To investigate characteristics of H isotope variation in long-chain n-alkanes (δDn-alkanes) from higher plants in surface soils under a single ecosystem, 12 samples from a basalt regolith were randomly collected from Damaping in Wanquan County of Zhangjiakou in North China. Molecular distribution and C (δ^13Cn-alkanes) and H isotopes of long-chain n-alkanes, as well as C isotopes of TOC (δ^13CTOC), were analyzed. Both δ^13CTOC and δ^13Cn-alkanes values from four representative dominant long-chain n-alkanes (n-C27, n-C29, n-C31, n-C33) derived from terrestrial higher plants show minor variations among the 12 samples, indicating the major contributor is from local grasses with a uniform C3 photosynthetic pathway. In contrast, variations in δ^13Cn-alkanes values of the four long-chain n-alkanes are relatively large, with the more abundant homologs generally showing more negative δDn-alkanes values and less variation. However, variation of 〈30‰ among weighted averaged δDn-alkanes values of the four long-chain n-alkanes is not only less than that among δDn-alkanes values for different modern terrestrial C3 grasses from the specific locations, but also less than the literature values of δDn-alkanes of long-chain n-alkanes for single species over different seasons. Thus, because the sources of long-chain n-alkanes in surface soils and sediments are similarly from multiple individual plants, our results are significant in confirming that paleoclimatic, paleoenvironmental and paleohydrological information can be interpreted more accurately from δDn-alkanes values of long-chain n-alkanes from sediments, particularly terrestrial sediments with organic matter derived from in-situ plants. 展开更多
关键词 C3 grassland surface soil long-chain n-alkanes compound-specific hydrogen isotope
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部