Experimental evidence indicates that chronic mechanical sub-occlusion of the intestine may damage the enteric nervous system (ENS), although data in humans are lacking. We here describe the first case of enteric deg...Experimental evidence indicates that chronic mechanical sub-occlusion of the intestine may damage the enteric nervous system (ENS), although data in humans are lacking. We here describe the first case of enteric degenerative neuropathy related to a congenital obstruction of the gut. A 3-year and 9-mo old girl began to complain of vomiting, abdominal distension, constipation with air-fluid levels at plane abdominal radiology. Her subsequent medical history was characterized by 3 operations: the first showed dilated duodeno-jejunal loops in the absence of occlusive lesions; the second (2 years later) was performed to obtain full-thickness biopsies of the dilated intestinal loops and revealed hyperganglionosis at histopathology; the third (9 years after the hyperganglionosis was identified) disclosed a Ladd's band which was removed and the associated gut malrotation was corrected. Repeated intraoperative full-thickness biopsies showed enteric degenerative neuropathy along with reduced interstitial cells of Cajal network in dilated loops above the obstruction and a normal neuromuscular layer below the Ladd's band. One year after the latest surgery the patient tolerated oral feeding and did well, suggesting that congenital (partial) mechanical obstruction of the small bowel in humans can evoke progressive adaptive changes of the ENS which are similar to those found in animal models of intestinal mechanical occlusion. Such ENS changes mimic neuronal abnormalities observed in intestinal pseudoobstruction.展开更多
The iteration-stopping scheme of turbo receiver, consisting of an inner multiple-input multiple-output (MIMO) detector and an outer turbo decoder, was studied in this paper. In the inner MIMO detector, only the reli...The iteration-stopping scheme of turbo receiver, consisting of an inner multiple-input multiple-output (MIMO) detector and an outer turbo decoder, was studied in this paper. In the inner MIMO detector, only the reliabilities of bits in those channel slots which included unreliable information bits were updated when the outer turbo code was a systematical one. In conjunction with the trigger events for stopping the turbo decoding, an iteration-stopping scheme of turbo receiver was proposed. Simulation results show that the proposed scheme has lower complexity, but almost the same error performance compared to the scheme with predetermined maximum iterations.展开更多
基金Supported by the Italian Ministry of Education, University and Research (CCOFIN Project No. 2004062155 to RDeG,2004055120 to GB and 2003064378 to RDeG, GB and VS)
文摘Experimental evidence indicates that chronic mechanical sub-occlusion of the intestine may damage the enteric nervous system (ENS), although data in humans are lacking. We here describe the first case of enteric degenerative neuropathy related to a congenital obstruction of the gut. A 3-year and 9-mo old girl began to complain of vomiting, abdominal distension, constipation with air-fluid levels at plane abdominal radiology. Her subsequent medical history was characterized by 3 operations: the first showed dilated duodeno-jejunal loops in the absence of occlusive lesions; the second (2 years later) was performed to obtain full-thickness biopsies of the dilated intestinal loops and revealed hyperganglionosis at histopathology; the third (9 years after the hyperganglionosis was identified) disclosed a Ladd's band which was removed and the associated gut malrotation was corrected. Repeated intraoperative full-thickness biopsies showed enteric degenerative neuropathy along with reduced interstitial cells of Cajal network in dilated loops above the obstruction and a normal neuromuscular layer below the Ladd's band. One year after the latest surgery the patient tolerated oral feeding and did well, suggesting that congenital (partial) mechanical obstruction of the small bowel in humans can evoke progressive adaptive changes of the ENS which are similar to those found in animal models of intestinal mechanical occlusion. Such ENS changes mimic neuronal abnormalities observed in intestinal pseudoobstruction.
基金the National Natural Science Foundation of China(No.60472098,60502046 and 60496316)
文摘The iteration-stopping scheme of turbo receiver, consisting of an inner multiple-input multiple-output (MIMO) detector and an outer turbo decoder, was studied in this paper. In the inner MIMO detector, only the reliabilities of bits in those channel slots which included unreliable information bits were updated when the outer turbo code was a systematical one. In conjunction with the trigger events for stopping the turbo decoding, an iteration-stopping scheme of turbo receiver was proposed. Simulation results show that the proposed scheme has lower complexity, but almost the same error performance compared to the scheme with predetermined maximum iterations.