期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
黄芩苷-小檗碱复合物及纳米晶在Caco-2细胞单层模型的吸收特性研究 被引量:1
1
作者 王继林 冯晓姣 +3 位作者 党文利 李紫微 刘志东 皮佳鑫 《天津中医药大学学报》 CAS 2023年第1期87-94,共8页
[目的]研究黄芩苷(BA)-小檗碱(BBR)复合物及纳米晶的吸收特性,探讨纳米晶技术对BA-BBR复合物吸收特性的改善。[方法]利用Cell Counting Kit-8(CCK-8)法筛选BA-BBR复合物及纳米晶对人结肠腺癌细胞系(Caco-2)细胞的给药浓度,构建Caco-2细... [目的]研究黄芩苷(BA)-小檗碱(BBR)复合物及纳米晶的吸收特性,探讨纳米晶技术对BA-BBR复合物吸收特性的改善。[方法]利用Cell Counting Kit-8(CCK-8)法筛选BA-BBR复合物及纳米晶对人结肠腺癌细胞系(Caco-2)细胞的给药浓度,构建Caco-2细胞单层模型探究BA-BBR复合物及纳米晶的跨膜转运方式,并且加入P-糖蛋白(P-gp)抑制剂维拉帕米研究对其累积转运量和表观渗透系数(Papp)的影响。[结果]复合物组中BA和BBR的Papp值均低于物理混合物组;与复合物组相比,纳米晶组中BA和BBR的累积转运量和Papp值均提高,Papp值为复合物组的1.3倍和2.3倍。加入维拉帕米后,复合物组BA和BBR的Papp值分别提高1.5倍和2.0倍,而纳米晶组Papp值无明显提高。[结论]BA-BBR复合物不同于物理混合物,具有低渗透性,同时易受到P-gp外排影响。纳米晶技术可以显著改善BA-BBR复合物的渗透性,并且减弱外排作用对其的影响。 展开更多
关键词 黄芩苷 小檗碱 人结肠腺癌细胞系细胞单层模型 累积转运量 表观渗透系数
下载PDF
Effects of Intercropping Patterns on Dry Matter Accumulation and Transportation of Maize(Zea mays L.) and Soybean[Glycine max(L.) Merrill] 被引量:3
2
作者 杨升辉 邱家训 +4 位作者 徐长帅 李洪杰 唐汝友 王素阁 李强 《Agricultural Science & Technology》 CAS 2013年第11期1545-1549,共5页
[Objective] The aim was to discuss the group dry matter accumulation and economic benefits under the patterns of intercropping maize (Zea mays L.) with soy-bean [Glycine max (L.) Merril ]. [Methods] Zhengdan-958 a... [Objective] The aim was to discuss the group dry matter accumulation and economic benefits under the patterns of intercropping maize (Zea mays L.) with soy-bean [Glycine max (L.) Merril ]. [Methods] Zhengdan-958 and Luhuang-1 were used as the testing breeds to study the effects of intercropping patterns on dry matter accumulation and transportation of maize and soybean in Huang-huai-hai. [Results] For maize, the dry matter accumulation amounts per hectare of intercropping was significant higher than that of the monoculture patterns, especial y after silking, when it reached extremely level; while for soybean, the dry matter accumulation amounts before flowering and after flowering of monocropping were al significantly higher than that of the intercropping patterns. For both maize and soybean, the transfer amounts of monocropping were al significantly or extremely significantly higher than that of intercropping; and the transfer ratio of maize intercropping was 0.59% higher than that of maize monocropping, while for soybean, it was 4.74% higher. Fitted dry matter accumulation with Logistic equation, it showed that the difference in maximum dry matter accumulation rate between maize monocropping and intercropping reached significant level, while for soybean, the maximum dry matter accumulation rate and its appearance time as wel as duration time between intercropping and monocropping were al reached significant level. The total land equivalent ratio of intercropping was 1.30. From yield and output value, the total yield of intercropping were 10.97 t/hm2, 0.64% and 326.85% higher than monocropping of maize and soy-bean, respectively. The total output value of intercropping was 25 796.23 yuan/hm2, respectively 12.67% and 104.68% higher than of maize and soybean monocropping. [Conclusion] The study lays a basis for improving grain yield and economic benefits. 展开更多
关键词 MAIZE SOYBEAN INTERCROPPING Dry matter accumulation and transportation Yield
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部