近日,SEGA Games Co.,Ltd.宣布将于2018年12月13日推出PlayStation4专用游戏《审判之眼:死神的遗言》繁体中文版,本作为法庭剧动作游戏,并由知名演员/艺人木村拓哉担纲主演。《审判之眼:死神的遗言》是一款以现代东京作为舞台的法庭剧...近日,SEGA Games Co.,Ltd.宣布将于2018年12月13日推出PlayStation4专用游戏《审判之眼:死神的遗言》繁体中文版,本作为法庭剧动作游戏,并由知名演员/艺人木村拓哉担纲主演。《审判之眼:死神的遗言》是一款以现代东京作为舞台的法庭剧动作游戏,玩家须抽丝剥茧追查连续残酷命案之谜。另外,本作的开发团队是由SEGA Games Co.,Ltd.董事CPO名越稔洋所率领的“人中之龙工作室”。工作室一路追求的目标就是“制作出能够满足成人的娱乐作品”,游戏的主线剧情从构想到完成脚本共花了三年的漫长时光,更加入与《人中之龙》系列大相径庭的全新要素“调查动作”,让玩家随着剧情一步步追查命案的真相。展开更多
从WinXP开始，微软的操作系统就支持多语种解决方案，用户通过微软推出的Windows XP Multilingual User Interface Pack(微软多语种用户界面软件包)可以将英文版本的操作系统转变成简体中文、繁体中文、德语，日语等多达33种语言中的任...从WinXP开始，微软的操作系统就支持多语种解决方案，用户通过微软推出的Windows XP Multilingual User Interface Pack(微软多语种用户界面软件包)可以将英文版本的操作系统转变成简体中文、繁体中文、德语，日语等多达33种语言中的任何一种。近日，基于WinXP64的Multilingual User Interface Pack也推出了。如果你手上还只有英文版的WinXP64，那就可以用它来完成中文版的“变身”了。展开更多
Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popu...Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popular complementary and alternative medicine modalities worldwide for the treatment of AP.The current evidence from basic research and clinical studies has shown that TCM has good therapeutic effects on AP.This review summarizes the widely used formulas,single herbs and monomers that are used to treat AP and the potential underlying mechanisms of TCM.Because of the abundance,low cost,and safety of TCM as well as its ability to target various aspects of the pathogenesis,TCM provides potential clinical benefits and a new avenue with tremendous potential for the future treatment of AP.展开更多
Background: There is increasing evidence showing the health benefits of various forms of traditional Chinese exercises(TCEs) on the glycemic profile in people with type 2 diabetes. However, relatively little is known ...Background: There is increasing evidence showing the health benefits of various forms of traditional Chinese exercises(TCEs) on the glycemic profile in people with type 2 diabetes. However, relatively little is known about the combined clinical effectiveness of these traditional exercises.This study was designed to perform a systematic review and meta-analysis of the overall effect of 3 common TCEs(Tai Ji Quan, Qigong, Ba Duan Jin) on glycemic control in adults with type 2 diabetes.Methods: We conducted an extensive database search in Cochrane Library, EMBASE, Pub Med, Web of Science, EBSCO, and China National Knowledge Infrastructure on randomized controlled trials published between April 1967 and September 2017 that compared any of the 3 TCEs with a control or comparison group on glycemic control. Data extraction was performed by 2 independent reviewers. Study quality was evaluated using the Cochrane Handbook for Systematic Reviews of Interventions, which assessed the risk of bias, including sequence generation, allocation concealment, blinding, completeness of outcome data, and selective outcome reporting. The resulting quality of the reviewed studies was characterized in 3 grades representing the level of bias: low, unclear, and high. All analyses were performed using random effects models and heterogeneity was quantified. We a priori specified changes in biomarkers of hemoglobin A1 c(in percentage) and fasting blood glucose(mmol/L) as the main outcomes and triglycerides, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein-cholesterol, 2-h plasma glucose, and fasting plasma glucose as secondary outcomes.Results: A total of 39 randomized, controlled trials(Tai Ji Quan = 11; Qigong = 6; Ba Duan Jin = 22) with 2917 type 2 diabetic patients(aged41à80 years) were identified. Compared with a control or comparison group, pooled meta-analyses of TCEs showed a significant decrease in hemoglobin A1 c(mean difference(MD) = ?0.67%; 95% confidence interval(CI): ?0.86% to ?0.48%; p < 0.00001) and fasting blood glucose(MD = ?0.66 mmol/L; 95%CI: ?0.95 to ?0.37 mmol/L; p < 0.0001). The observed effect was more pronounced for interventions that were medium range in duration(i.e., >3à<12 months). TCE interventions also showed improvements in the secondary outcome measures. A high risk of bias was observed in the areas of blinding(i.e., study participants and personnel, and outcome assessment).Conclusion: Among patients with type 2 diabetes, TCEs were associated with significantly lower hemoglobin A1 c and fasting blood glucose.Further studies to better understand the dose and duration of exposure to TCEs are warranted.展开更多
文摘近日,SEGA Games Co.,Ltd.宣布将于2018年12月13日推出PlayStation4专用游戏《审判之眼:死神的遗言》繁体中文版,本作为法庭剧动作游戏,并由知名演员/艺人木村拓哉担纲主演。《审判之眼:死神的遗言》是一款以现代东京作为舞台的法庭剧动作游戏,玩家须抽丝剥茧追查连续残酷命案之谜。另外,本作的开发团队是由SEGA Games Co.,Ltd.董事CPO名越稔洋所率领的“人中之龙工作室”。工作室一路追求的目标就是“制作出能够满足成人的娱乐作品”,游戏的主线剧情从构想到完成脚本共花了三年的漫长时光,更加入与《人中之龙》系列大相径庭的全新要素“调查动作”,让玩家随着剧情一步步追查命案的真相。
文摘从WinXP开始，微软的操作系统就支持多语种解决方案，用户通过微软推出的Windows XP Multilingual User Interface Pack(微软多语种用户界面软件包)可以将英文版本的操作系统转变成简体中文、繁体中文、德语，日语等多达33种语言中的任何一种。近日，基于WinXP64的Multilingual User Interface Pack也推出了。如果你手上还只有英文版的WinXP64，那就可以用它来完成中文版的“变身”了。
基金National Natural Science Foundation of China,No.30171167,No.30901945Specialized Research Fund for the Doctoral Program of Higher Education,No.20130201130009+1 种基金Science and Technology Program of Shaanxi Province,No.2012KTCQ03-15Science Research Foundation of the Second Affiliated Hospital of Xi'an Jiaotong University,No.YJ(QN)201311)
文摘Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popular complementary and alternative medicine modalities worldwide for the treatment of AP.The current evidence from basic research and clinical studies has shown that TCM has good therapeutic effects on AP.This review summarizes the widely used formulas,single herbs and monomers that are used to treat AP and the potential underlying mechanisms of TCM.Because of the abundance,low cost,and safety of TCM as well as its ability to target various aspects of the pathogenesis,TCM provides potential clinical benefits and a new avenue with tremendous potential for the future treatment of AP.
基金supported by the National Natural Science Foundation of China(No.81501956)Fok Ying-Tong Education Foundation of China(No.161092)Shanghai Key Lab of Human Performance(Shanghai University of Sport,No.11DZ2261100)
文摘Background: There is increasing evidence showing the health benefits of various forms of traditional Chinese exercises(TCEs) on the glycemic profile in people with type 2 diabetes. However, relatively little is known about the combined clinical effectiveness of these traditional exercises.This study was designed to perform a systematic review and meta-analysis of the overall effect of 3 common TCEs(Tai Ji Quan, Qigong, Ba Duan Jin) on glycemic control in adults with type 2 diabetes.Methods: We conducted an extensive database search in Cochrane Library, EMBASE, Pub Med, Web of Science, EBSCO, and China National Knowledge Infrastructure on randomized controlled trials published between April 1967 and September 2017 that compared any of the 3 TCEs with a control or comparison group on glycemic control. Data extraction was performed by 2 independent reviewers. Study quality was evaluated using the Cochrane Handbook for Systematic Reviews of Interventions, which assessed the risk of bias, including sequence generation, allocation concealment, blinding, completeness of outcome data, and selective outcome reporting. The resulting quality of the reviewed studies was characterized in 3 grades representing the level of bias: low, unclear, and high. All analyses were performed using random effects models and heterogeneity was quantified. We a priori specified changes in biomarkers of hemoglobin A1 c(in percentage) and fasting blood glucose(mmol/L) as the main outcomes and triglycerides, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein-cholesterol, 2-h plasma glucose, and fasting plasma glucose as secondary outcomes.Results: A total of 39 randomized, controlled trials(Tai Ji Quan = 11; Qigong = 6; Ba Duan Jin = 22) with 2917 type 2 diabetic patients(aged41à80 years) were identified. Compared with a control or comparison group, pooled meta-analyses of TCEs showed a significant decrease in hemoglobin A1 c(mean difference(MD) = ?0.67%; 95% confidence interval(CI): ?0.86% to ?0.48%; p < 0.00001) and fasting blood glucose(MD = ?0.66 mmol/L; 95%CI: ?0.95 to ?0.37 mmol/L; p < 0.0001). The observed effect was more pronounced for interventions that were medium range in duration(i.e., >3à<12 months). TCE interventions also showed improvements in the secondary outcome measures. A high risk of bias was observed in the areas of blinding(i.e., study participants and personnel, and outcome assessment).Conclusion: Among patients with type 2 diabetes, TCEs were associated with significantly lower hemoglobin A1 c and fasting blood glucose.Further studies to better understand the dose and duration of exposure to TCEs are warranted.
